• Title/Summary/Keyword: Compound action potential

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Effect of Electromyographic Biofeedback Training on the Muscle Activities of Unilateral Facial Palsy (근전도 바이오피드백을 이용한 훈련이 안면신경마비 환자의 운동학습에 미치는 영향)

  • Kim, Won-Ho;Park, Eun-Young;Chang, Ki-Yeon;Lee, Young-Jung
    • Physical Therapy Korea
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    • v.9 no.3
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    • pp.101-111
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    • 2002
  • The purpose of this study was to determine EMG biofeedback training effect on the muscle activities in 3 unilateral facial palsy patients along with multiple baseline design across subjects. The auditory feedback about facial muscles (orbicularis oris, orbicularis oculi, frontalis) was provided with each patient during facial exercise training. Electromyographic (EMG) activity during maximal voluntary contraction and maximal compound muscle action potential (CMAP) amplitude elected by supramaximal electrical stimulation on facial nerve of facial muscles were measured pre- and post- EMG biofeedback training to evaluate motor learning. EMG activity during maximal voluntary contraction was increased after EMG biofeedback training and CMAP amplitude elected by supramaximal electrical stimulation was not changed in all subjects. The results indicate that EMG biofeedback training is useful method to improve motor learning of facial excercise training in unilateral facial palsy patients.

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Therapeutic Functor that calls semantic Argument -Focusing on the compound nouns in Sijo

  • Park, In-Kwa
    • International Journal of Advanced Culture Technology
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    • v.5 no.3
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    • pp.35-39
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    • 2017
  • The human body is structured as sentence of healing. This study examines how the mechanism of healing works in the human body by the narrative relation of functor and argument. So, we predict the way of extreme healing by literary or human narrative. For this purpose, we analyze the principle that the emotional and semantic arguments are called by the functor set by the sentences containing the fingerprints of mind in Gosijo and the mechanism of healing works extensively. We analyze the process of the transition from the narrative of the literary to the narrative of the human body. Thus, the barcode of the healing, which is made up of the relationship between the functor of the literature and the argument, is transferred to the human body and it is judged that the fingerprint of the human mind is operated through the stage of encoding and re-encoding due to the action potential. In addition, it was predicted that the neurotransmitters such as dopamine and the secretion of hormones would be promoted and the healing level would be increased. In results, we conclude that the function of argument and functor which contains the fingerprint of the mind in the third sound step on the last sentence of Gosijo is transferred to the human body and is especially heavily focused and operate with healing.

Segmental Sensory Nerve Conduction Study in Vibration Exposed Subjects

  • Kim Mi-Jung;Yoon Cheol-In;Choi Hyun-Ju
    • Biomedical Science Letters
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    • v.11 no.2
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    • pp.193-199
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    • 2005
  • The present study was performed to assess peripheral neural involvement by exposure to hand-arm vibration. Segmental sensory nerve conduction in the median and ulnar nerves were measured in shipyard workers exposed to vibration. The subjects were 47 male adults exposed to hand-arm vibration and 7 healthy male controls. The subjects underwent an extensive bilateral neurophysiological examination. Sensory compound nerve action potential (SNAP) of the median and ulnar nerves in palm-finger and wrist-palm segments were measured by antidromic method. And SNAP of the median and ulnar nerves in wrist-proximal finger and wrist-distal finger segments were measured by orthodromic method. Result of sensory nerve conduction study was abnormal in 31 patients $(66\%)$ and normal in 16 patients $(34\%)$ of subjects. The pathological pattern in the hand-arm vibration exposed group was 13 patients $(28\%)$ of carpal tunnel syndrome, 18 patients $(38\%)$ of distal sensory neuropathy, 7 patients $(15\%)$ of multifocal and 1 patient $(2\%)$ of Guyon syndrome. The present study indicates that vibration-induced nerve impairments exist both in the finger-palm and palm-wrist segment of median and ulnar sensory nerves. The results suggest that segmental sensory nerve conduction study would be useful as objective indication of peripheral nerve impairment induced by the hand-arm vibration.

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Gomisin G Suppresses the Growth of Colon Cancer Cells by Attenuation of AKT Phosphorylation and Arrest of Cell Cycle Progression

  • Maharjan, Sony;Park, Byoung Kwon;Lee, Su In;Lim, Yoongho;Lee, Keunwook;Lee, Younghee;Kwon, Hyung-Joo
    • Biomolecules & Therapeutics
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    • v.27 no.2
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    • pp.210-215
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    • 2019
  • Colorectal cancer is one of the leading causes of cancer related death due to a poor prognosis. In this study, we investigated the effect of Gomisin G on colon cancer growth and examined the underlying mechanism of action. We found that Gomisin G significantly suppressed the viability and colony formation of LoVo cells. Gomisin G reduced the phosphorylation level of AKT implying that Gomisin G suppressed the PI3K-AKT signaling pathway. Gomisin G also induced apoptosis shown by Annexin V staining and an increased level of cleaved poly-ADP ribose polymerase (PARP) and Caspase-3 proteins. Furthermore, Gomisin G remarkably triggered the accumulation of cells at the sub-G1 phase which represents apoptotic cells. In addition, the level of cyclin D1 and phosphorylated retinoblastoma tumor suppressor protein (Rb) was also reduced by the treatment with Gomisin G thus curtailing cell cycle progression. These findings show the suppressive effect of Gomisin G by inhibiting proliferation and inducing apoptosis in LoVo cells. Taken together, these results suggest Gomisin G could be developed as a potential therapeutic compound against colon cancer.

The Effect of Diabetes Mellitus on Postoperative Electrodiagnostic Outcomes of Carpal Tunnel Syndrome (손목터널증후군 환자에서 당뇨병이 수술 후 전기생리학적 결과에 미치는 영향)

  • Kwak, Jung Min;Jeong, Young Ha;Kang, Seok;Yoon, Joon Shik
    • Journal of Electrodiagnosis and Neuromuscular Diseases
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    • v.20 no.2
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    • pp.91-97
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    • 2018
  • Objective: The aim of this study was to compare the electrodiagnostic outcomes of carpal tunnel release in patients with and without diabetes with carpal tunnel syndrome (CTS), and to evaluate the effect of diabetes mellitus (DM) on electrodiagnostic outcomes. Method: We conducted a retrospective analysis of 67 patients with electro-diagnostic evidence of CTS. Patients were classified into two groups according to the presence of DM. Both groups were evaluated using nerve conduction studies preoperatively and 3 weeks and 3 months postoperatively. Results: There were no statistical differences in any of the electrodiagnostic parameters between groups 3 weeks postoperatively. However, there were statistical differences in the amplitude and the latency of compound muscle action potential, and sensory nerve conduction velocity 3 months postoperatively. Conclusion: Patients with DM did not show a significantly different outcome 3 weeks after surgery but showed a worse electrodiagnostic outcome 3 months after surgery than those without DM.

The Effect of Irradiation During Resistance Exercise Using a Diagonal Pattern on the Excitability of Nerves (대각선 패턴에서 저항운동 시 발생한 방산의 효과가 신경의 흥분성에 미치는 영향)

  • Rhee, Min-Hyung;Choi, Su-Hong;Ha, Kyung-Jin;Lee, Sang-Yeol
    • PNF and Movement
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    • v.19 no.1
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    • pp.97-104
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    • 2021
  • Purpose: The human body can experience a variety of injuries. As a result, it may be difficult to directly treat the damaged area. In such a case, indirect treatment is required. Indirect treatment is typically PNF treatment. Morphological changes in muscle have been confirmed through several previous studies; however, few studies have analyzed neurological changes. Therefore, the purpose of this study was to determine how irradiation during resistance exercise using a diagonal pattern effects neurological excitability. Methods: Electromyography was performed on 13 healthy adults. A compound muscle action potential (CMAP) was obtained through a median motor nerve conduction velocity test, which was conducted before and after performing the irradiation exercise and general exercise. Results: Compared to baseline measurements, there was no significant difference in the latency of the irradiation exercise and general exercise. The amplitude of the CMAP measured after the irradiation exercise was significantly higher than after general exercise. Conclusion: Neurological excitability was high in irradiation during resistance exercise using a diagonal pattern. When clinically direct treatment is difficult, it is thought that irradiation can be used indirectly as a technique to induce nerve excitability.

Lipid oxidation and antioxidant mechanisms in different matrix (매질(matrix)에 따른 지방산화 및 산화방지능 메커니즘)

  • Yi, BoRa;Kim, Mi-Ja;Lee, JaeHwan
    • Food Science and Industry
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    • v.51 no.2
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    • pp.127-135
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    • 2018
  • The action of antioxidants was different depending on the environments where antioxidants were located. Although basic mechanisms of lipid oxidation and antioxidants were related each other, their contribution on the degree of oxidation was different. In thisreview, terminology on antioxidant properties were defined such as antioxidant activity and antioxidant capacities. In addition, antioxidant mechanisms including primary and secondary antioxidants or hydrogen donating or electron transferring antioxidants were introduced. Also, the impact of physical points of view and antioxidant polar paradox were introduced. Depending on the types of food matrice including bulk oil, oil-in-water emulsion (O/W), or solid state, antioxidant actions showed different degree and this point was explained in detail.

Guillain-Barre Syndrome after Minimally Invasive Lumbar Procedure: A Case Report (요추부 최소침습적 시술 후 길랑-바레 증후군: 증례보고)

  • Lee, Bong-Yeon;Yoon, Seo-Ra;Ryu, Su-Ra;Choe, Yu-Ri
    • Journal of Electrodiagnosis and Neuromuscular Diseases
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    • v.20 no.2
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    • pp.159-163
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    • 2018
  • Guillain-Barre syndrome (GBS) after trauma and general orthopedic surgery is rare. A 74-year-old woman showed ascending paralysis symmetrically, dysarthria, dysphagia and areflexia on 14 days after minimally invasive endoscopic thermoannuloplasty on L4-5 level. Brain and lumbar magnetic resonance imaging demonstrate no abnormal findings. The electrodiagnostic study showed prolonged distal motor, sensory latencies and F-wave latencies and reduced amplitude of compound muscle action potential in nerves of upper and lower extremities. In the cerebrospinal fluid (CSF) examination, total protein and IgG were increased. We diagnosed Guillain-Barre Syndrome based on clinical features, electrodiagnostic study and CSF examination and the patient improved symptoms after immunoglobulin injection and rehabilitation. Because the occurrence of GBS after minimally invasive procedure has not been reported, we report a case of GBS after minimally invasive procedure with literature review.

Effects of Inhibitors on Corrosion Resistance of Steel in CaCl2 Solution Based on Response Surface Analysis

  • Park, Tae-Jun;Jang, HeeJin
    • Corrosion Science and Technology
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    • v.20 no.3
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    • pp.129-142
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    • 2021
  • Effects of corrosion inhibitors (i.e., sodium nitrite, sodium hexametaphosphate, trimethylamine (TEA), sugar, and urea) on the corrosion resistance of carbon steel in CaCl2 solution were investigated. The test solution was designed with response surface methodology of design of experiments (DOE) in the range of 0 ~ 50 ppm for NaNO2, 0 ~ 200 ppm for (NaPO3)6, 0 ~ 2000 ppm for TEA, 0 ~ 3000 ppm for sugar, 0 ~ 200 ppm for urea with 3 wt% CaCl2. The corrosion potential and the corrosion rate were measured with potentiodynamic polarization tests and analyzed statistically to find main effects of inhibitor concentrations and interactions between them. As a result, hexametaphosphate was the most effective compound in reducing the corrosion rate. Sugar also reduced the corrosion rate significantly possibly because it covered the surface effectively with a high molecular weight. The inhibiting action of sugar was found to be enhanced by adding trimethylamine into the solution. Nevertheless, trimethylamine did not appear to be effective in inhibiting corrosion by itself. However, urea and sodium nitrite showed almost no inhibition on corrosion resistance of steel.

Antioxidant Activities and the Effect of Reducing Serum Alcohol Concentration of Lentinus edodes (표고버섯의 항산화능과 알코올분해능에 미치는 영향)

  • Kim, Chae-Hyun;Jeong, Jong-Gil
    • The Korea Journal of Herbology
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    • v.24 no.4
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    • pp.159-164
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    • 2009
  • Objectives : The purpose of this study is to evaluate antioxidant activities and reducing serum alcohol concentration of extract of Lentinus edodes on the alcohol administered rats. Methods : Antioxidant effect was measured by total phenolic compound and DPPH-radical scavenging activity of extract of Lentinus edodes in vitro. Blood alcohol concentration, aldehyde concentration, malondialdehyde concentration, glutathion concentration were measured in vivo. Results : The extract of Lentinus edodes increased DPPH-radical scavenging activity dose-dependently. The water extract with boiling water showed lower antioxidant activity and phenolic content than 70% ethanol extract in vitro. Blood alcohol concentration was significantly reduced by pre-treatment of ethanol extract of Lentinus edodes. The effect was more significant than commercial product used as a positive control. Conclusions : This study suggest that Lentinus edodes can be a potential nature resource for the management of ethanol toxicity although the mechanism of action involved in the treatment remains to be explored.