• 제목/요약/키워드: Composition methods

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위치 종속 유사도 스펙트럼을 이용한 단백질 서열의 아미노산 조성 추정 (Estimating Amino Acid Composition of Protein Sequences Using Position-Dependent Similarity Spectrum)

  • 지상문
    • 한국정보과학회논문지:소프트웨어및응용
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    • 제37권1호
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    • pp.74-79
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    • 2010
  • 단백질의 아미노산 조성은 생물정보학의 여러 문제를 해결하기 위한 기초적인 정보로 자주 활용된다. 본 논문에서는 아미노산간의 진화적인 연관성을 정의한 BLOSUM 행렬에서 유도한 유사도 함수를 사용하여 아미노산 조성을 결정한다. 이러한 방법은 생물학적인 연관성이 있는 단백질 서열일수록 비슷한 아미노산 조성을 갖도록 한다. 또한 단백질의 구조와 기능에 중요한 역할을 하는 위치-특이적인 아미노산의 분포를 추정하기 위해서 레이더나 음성 신호의 스펙트럼 분석에 사용되는 개념인 시간-종속 분석, 시간 해상도와 주파수 해상도의 개념을 적용하였다. 제안한 방법을 단백질의 세포내 위치예측에 적용하여 기존의 아미노산 조성 추정 방법을 사용하는 것보다 크게 향상된 성능을 보임을 확인하였다.

Prediction of Protein Secondary Structure Content Using Amino Acid Composition and Evolutionary Information

  • Lee, So-Young;Lee, Byung-Chul;Kim, Dong-Sup
    • 한국생물정보학회:학술대회논문집
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    • 한국생물정보시스템생물학회 2004년도 The 3rd Annual Conference for The Korean Society for Bioinformatics Association of Asian Societies for Bioinformatics 2004 Symposium
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    • pp.244-249
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    • 2004
  • There have been many attempts to predict the secondary structure content of a protein from its primary sequence, which serves as the first step in a series of bioinformatics processes to gain knowledge of the structure and function of a protein. Most of them assumed that prediction relying on the information of the amino acid composition of a protein can be successful. Several approaches expanded the amount of information by including the pair amino acid composition of two adjacent residues. Recent methods achieved a remarkable improvement in prediction accuracy by using this expanded composition information. The overall average errors of two successful methods were 6.1% and 3.4%. This work was motivated by the observation that evolutionarily related proteins share the similar structure. After manipulating the values of the frequency matrix obtained by running PSI-BLAST, inputs of an artificial neural network were constructed by taking the ratio of the amino acid composition of the evolutionarily related proteins with a query protein to the background probability. Although we did not utilize the expanded composition information of amino acid pairs, we obtained the comparable accuracy, with the overall average error being 3.6%.

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Effect of Proximate Composition Ratios for Biogas Production

  • Kim, Min-Jee;Kim, Soo-Ah;Kim, Sang-Hun
    • Journal of Biosystems Engineering
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    • 제42권3호
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    • pp.155-162
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    • 2017
  • Purpose: The objective of this study was to evaluate the biogas productivity of agricultural by-products (ABPs) based on their proximate composition. Specifically, the effects of proximate composition were investigated, and a new mixing method was developed using various ABPs that are difficult to digest for biogas production. Methods: Experiments were conducted to compare the biogas productivity between a single ABP and a mixture of ABPs that had the same proximate composition as the single ABP. To match the proximate compositions of radish waste and corn distiller's dried grains with solubles (DDGS), mixed ABPs were made from various ABPs. Biogas potential tests (BMP tests) were performed at an organic loading rate (OLR) of 2.5 g VS/L and a feed to microorganism ratio (F/M) of 0.5 under the mesophilic condition. Results: The individual ABPs (radish and corn DDGS) and the mixed ABPs (cabbage waste with skim milk waste, bean-curd waste with skim milk waste, and some others) produced similar amounts of biogas. Conclusions: The new mixing method based on proximate composition can be applied to other ABPs and organic wastes from factories and municipal waste treatment plants to develop renewable energy and effective waste treatment methods.

인쇄 모틀의 방지를 위한 제지도공 기술개발 (제2보)-도공안료 조성과 도공량에 따른 도공지의 광학적 특성 변화 (Development of Paper Coating Technologies to Prevent Print Mottle (II)-Optical Properties of Coated Papers Affected by Coating Pigment Composition and Coat Weight)

  • 정준경;신동소;이학래
    • 펄프종이기술
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    • 제29권1호
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    • pp.26-35
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    • 1997
  • A study was carried out to investigate such optical properties of coated papers as brightness, opacity and gloss affected by the coating pigment composition and coat weight using clay, ground calcium carbonate, precipitated calcium carbonate, and plastic pigment as pigments. The effects of drying methods and supercalendering on optical properties were also evaluated. Gloss increased abruptly while brightness and opacity decreased slightly by supercalendering due to surface smoothing and consolidating effects of the coating layers. Optical properties changed little by drying methods. Pigment composition showed significant influences on optical properties. Brightness of coated papers decreased or increased linearly as the coat weight was increased depending on the pigment composition, while opacity increased linearly for all formulations. Gloss increased abruptly at low coat weights for all formulations and approached a plateau value at coat weight of 15-20g/$m^2$. Third order polynomial regression equations relating the coat weight with gloss have been derived and tabulated.

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요리 방법이 쇠고기의 지방산 조성에 미치는 영향 (Effect of Cooking Method to Fatty Acid Composition of Ground Beef)

  • 곽순미;이숙미;조정순
    • 한국응용과학기술학회지
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    • 제9권2호
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    • pp.181-187
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    • 1992
  • This study was designed evaluate the change of fat content according to cooking methods of ground beef. The results are summarized as follows. 1. The fat content of ground beef is the lowest in boiling cooking method. 2. The fatty-acids composition of ground beef is mainly palmitic and oleic acids. The fatty acids hardly change according to cooking methods. 3. P/S ratio is inclined to increase a bit after cooking than pre-cooking. From all the results obtained in this study it can be conclude that fat content is the lowest in boiling and microwaving cooking methods and fatty acid composition is mainly palmitic and oleic acids.

구성형태(構成形態)에 따른 파티클과 파이버로 제조(製造)한 패널의 물리적 및 기계적 성질 (Physical and Mechanical Properties of Panels Fabricated with Particle and Fiber by Composition Types)

  • 윤형운;이필우
    • Journal of the Korean Wood Science and Technology
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    • 제20권2호
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    • pp.9-22
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    • 1992
  • The aim of this research was to investigate physical and mechanical properties of various composition panels, each fabricated with a ratio of fiber to particle of 2 to 10. Type A consisted of fiber-faces and particle-core in layered-mat system. Type B consisted of fiberboard-faces on particleboard-core. Type C consisted of fibers and particles in mixed-mat system. The results obtained from tests of bending strength, internal bond, screw holding strength and stability were as follows: 1. The bending strength and internal bonding of both the Type A panel and the Type B panel were higher than those of the Type C panel and three-layered particle board. 2. The mechanical properties of the Type C panel showed the lowest values of all composition methods. It seems that the different compression ratios of the particle and fiber interrupted the densification of the fibers when hot pressed. 3. The dimensional stability of layered-mat system panels consising of fiber-faces and particle-core was better the than control particleboard. 4. In composition methods of particle and fiber, layered-composition method was more resonable than mixed-composition. The Type B panel had the highest mechanical properties of all the composition types. 5. The Type A panel was considered the ideal composition method because of its resistance to delamination between the particle-layer and the fiber-layer and because of its lower adhesive content and more effective manufa cturing process.

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Food Composition Database in Korea

  • Chun, Hye-Kyung;Park, Hong-Ju;Lee, Sung-Hyeon
    • Nutritional Sciences
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    • 제7권1호
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    • pp.47-52
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    • 2004
  • The food composition database is used to evaluate the nutritional value of foods in Korea. It is used as a source for basic data in many fields, not only for the establishment of the National Food Supply Plan but also for nutritional research, to aid in the drafting of the National Food Policy, and in clinical and epidemiological research. The database is also used by institutional and commercial food services and by the food processing industry among others. In 1970, the Rural Development Administration(RDA) published the "Korean Food Composition Table" for the first time and it has since become the established authority on food composition for the entire nation. The latest published food composition table (the 6th edition, published by the National Rural Living Science Institute, KDA) covers 2,337 kinds of foods and consists of two volumes. The National Rural Living Science Institute, the Korea Food and Drug Administration, and the National Fisheries Research and Development Institute have continuously improved production of food composition data in Korea. As consumers have grown more interested in the quality and safety of foods and raw agricultural products, we can expect even further development of food composition data through improvements in quality and increases in quantity. We need to develop more comprehensive food composition data by diversifying the kinds of foods that are included, unifying analytical methods, and increasing the number of nutrients covered. Moreover, food composition data must be modified in other ways to make for a better food composition database for the convenience of users. of users.

선행조건이 명세되어 있지 않은 복합 리팩토링에 대한 조립성 검사 (A Composition Check of Composite Refactorings Not Having a Specification of Precondition)

  • 김경민;장필재;김태공
    • 정보처리학회논문지D
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    • 제18D권1호
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    • pp.23-34
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    • 2011
  • 최근의 소프트웨어 개발에서는 리팩토링이 활발하게 이용되고 있다. 리팩토링에 대한 관심이 높아지면서 요소 리팩토링을 정의해서 이들의 조립을 통해 더 큰 종류의 복합 리팩토링을 처리하려는 연구들이 많이 진행되고 있다. 복합 리팩토링은 조합된 요소 리팩토링의 순서대로 처리되기 때문에 프로그램에 실제 적용하기에 앞서 적용 가능성을 판단하는 것이 중요하다. 기존 연구들에서는 요소 리팩토링들의 선 후행조건들로부터 복합 리팩토링에 대한 선행조건을 계산하여 적용 가능성을 판단하고 있다. 이것은 선행조건이 정의되어 있는 복합 리팩토링만 판별할 수 있으며 선행조건이 정의되어 있지 않은 복합 리팩토링에 대해서는 적용 가능성을 판단할 수 없는 문제점이 있다. 본 연구에서는 복합 리팩토링의 명세를 추가로 정의 하지 않고 요소 리팩토링만으로 조립 가능 여부를 판단하고자 한다. 이를 위해 요소 리 팩토링을 명세하는 방법과 조립성 검사 방법을 제안한다. 이를 기반으로 프로토타입 도구를 개발해 보고, 적용사례를 통해 선행조건이 명세되어 있지 않은 복합 리팩토링들의 조립성 검사를 확인해봄으로써 본 연구의 효용성을 검토해본다.

의료시설 내 건축공간구성을 통한 치유환경 조성에 관한 연구 - 소우 후지모토 의료시설 사례들의 공간분석을 중심으로 (A Study on the Healing Environment with Architectural Spatial Composition in Healthcare Facilities - Focused on the Space Analysis of Sou Fujimoto's Healthcare Projects)

  • 정태종
    • 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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    • 제25권2호
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    • pp.17-25
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    • 2019
  • Purpose: The analysis of spatial composition is required for the creation of healing environment in healthcare facilities. This study has been accomplished to provide basic data for the planning and design of hospital architecture. Methods: Literature review of healing environment and investigation on characteristics of spatial composition in healthcare facilities have been conducted. The architectural plans of four Sou Fujimoto's healthcare projects have been analyzed with space syntax. Results: The result of this research can be summarized as followed. First of all, the healing environments are consisted with architectural composition in addition to physical and psychological factors for healing environment. The second one is that the characteristics of spatial composition in Sou Fujimoto's healthcare projects are different private/public/corridor relationships in program configuration, loop or one direction circulation, combined or independent corridor with program, and radical or linear connection in spatial connection methods. The third one is that the characteristics of spatial composition in selected cases through space syntax are high variation on integration, low variation on connectivity, and high distribution in main circulation on ERAM(3). Implications: In addition to the specific spatial composition in healthcare facilities of the architect's project, it is necessary to analyze the relationship with other factors and facilities to develop the planning of hospital architecture.

The Effects of Circuit Weight Training Programs including Aquatic Exercises on the Body Composition and Serum Lipid Components of Women with Obesity

  • Kim, Gi-Won;Hwang, Ryong
    • The Journal of Korean Physical Therapy
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    • 제23권6호
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    • pp.61-69
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    • 2011
  • Purpose: This study investigated the changes in body composition and serum lipid composition in obese women that were caused by a 12-week circuit exercise regime including both field and aquatic activities. Methods: Subjects comprised a total of 36 women who had a BMI of more than $25kg/m^2$. The simple obesity group (n=17) had no current or past record of medical complications, whereas the group with complications (n=19) also suffered from hypertension and/or diabetes. The circuit exercise program consisted of 12 weeks of 60%HRmax exercise sessions, five days a week. Results: While changes in every variable of body composition were significant, there was no statistically significant difference in the changes in serum lipid composition variables. With the exception of BMI, the correlation between the simple/complicated groups and exercising was statistically insignificant. Conclusion: These findings suggest that while a complex circuit weight exercise program that includes aquatic exercises significantly and positively alters obese patients' body composition it does not create statistically significant changes in their serum lipid composition. It can still be concluded, however, that increasing the duration of the exercise program would be effective to influence this. Moreover, personalized exercise programs that fit the needs of the individual participants seem necessary, given that the effect of exercise on body composition and serum lipid composition was greater in patients with simple obesity than in those with complications.