• Title/Summary/Keyword: Component development

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Consideration of Urgent Facing Strategies for the Designation of Customs Free Zone of Incheon City (인천항 관세자유지역 지정시 당면과제 고찰)

  • 박창호;이기철;노흥승;여기태
    • Journal of Korea Port Economic Association
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    • v.17 no.2
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    • pp.183-204
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    • 2001
  • This study is intended for the development of urgent facing strategies for the designation of a CFZ(Customs Free Zone) in Incheon city. First, it analyzes the current status of the Incheon CFZ. Next, it suggests several strategies for successfully growing the CFZ of Incheon City. Finally, it develops and proposes a method for establishing an integrated management system for the effective management of the CFZ. The key findings of this study are as follows: First, the CFZ should provide state-of-the-art movement of port logistics, create new added value caused by the movement of logistics, and provide other public support. The Incheon CFZ should be developed in three stages: an inducement stage in 2002-2005, a growth stage in 2005-2008, and an implementation stage in 2008-2011. Second, The parties responsible for the management of the CFZ would be as follows: for the port area, the Ministry of Maritime and Fisheries; for the back space of CFZ, Incheon City; and for port management, port management companies. However, a committee for CFZ management is strongly suggested for the improved efficiency and effectiveness of CFZ management. Furthermore, additional regulations ensuring the role of local government will likely be necessary for the sucessful designation and sustainable management of the CFZ. Third, For the creation of additional revenue, reformation of the current laws of the CFZ are recommended in the area of business administration. Fourth, A strategic marketing plan that supports the successful management of the companies of the CFZ will be a key component in the success of the CFZ. Thus, the new marketing plan should be developed in the near future based on case studies of other CFZs. Fifth A method for an integrated CFZ management system was developed and suggested for the comprehensive and transparent management of port logistics.

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Comparison of Chemical Components among varieties of Elephant-food (Amorphophallus konjac, K.) (수집종긴의 구약감자 성분비교)

  • HeDuckLee
    • Korean Journal of Plant Resources
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    • v.9 no.3
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    • pp.218-223
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    • 1996
  • This study was carried out to obtain a basic information for the improvement of human health and the development of variety through the analysis of inorganic compounds. contents of amino acids and polysaccarides on three elephant foods, Amorphophallus konjac, collected from Kumsan, Japan and China. The contents of mannan as a carbohydrate of a major component in an elephant food was slightly high in Kumsan than that of Japan and China variety. Degree of VIscosity of an elephant food depends upon the contents of soluble free sugars and amino acids contents of these free sugars were high in the order of Japan, China and Kumsan variety. The analytical results on inorganic compounds in an elephant food were shown as follows; The contents of potasium, phosphate and ferrin of Kumsan variety were shown to be higher than those of China and Japan, while sodium and caleium were appeared to be highter in China chip

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Effects of 3-Phenyl-1-isoquinolinamine on the Metabolism of ${\beta}$-Amyloid Precursor Protein in Neuroblastoma Cells (3-페닐-1-이소퀴놀린아민이 신경세포에서 베타 아밀로이드 전구단백질의 대사에 미치는 영향)

  • Leem, Jae-Yoon;Cho, Won-Jea
    • YAKHAK HOEJI
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    • v.54 no.6
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    • pp.529-534
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    • 2010
  • Alzheimer's disease (AD) is characterized pathologically by the presence of intracellular neurofibrillary tangles and deposition of ${\beta}$-amyloid ($A{\beta}$) peptides, which are generated by processing of amyloid precursor protein (APP). It is urgent to develop effective therapies for the treatment of AD, since our society rapidly accelerate aging. $A{\beta}$ peptides have been believed to be neurotoxic and now are also considered to have effects on the mechanism of memory formation. Recently, we investigated that a quinoline compound from natural product reduced the secretion of $A{\beta}$ from the neuroblastoma N2a cells (NL/N cell line) overexpressing APPswe. In this study, 3-phenyl-1-isoquinolinamine, a synthetic isoquinoline compound was analyzed to determine its effects on the metabolism of APP. It inhibited the secretion of $A{\beta}$ peptides from the N2a NL/N cell line. Beta-site APP cleaving enzyme (BACE) fluorescence resonance energy transfer (FRET) assay revealed that it inhibited BACE activity in a dose dependent manner. Immunoblotting study showed that it inhibited APP stabilization and expression and it slightly increased the stablization and the expression of ${\gamma}$-secreatase component from the N2a NL/N cell line. We suggest that 3-phenyl-1-isoquinolinamine inhibits APP metabolism and $A{\beta}$ generation by the means of BACE inhibitory mechanism. This is the first report that 3-phenyl-1-isoquinolinamine inhibits the secretion of $A{\beta}$ peptides from neuroblastoma cells.

A CYBER SECURITY RISK ASSESSMENT FOR THE DESIGN OF I&C SYSTEMS IN NUCLEAR POWER PLANTS

  • Song, Jae-Gu;Lee, Jung-Woon;Lee, Cheol-Kwon;Kwon, Kee-Choon;Lee, Dong-Young
    • Nuclear Engineering and Technology
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    • v.44 no.8
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    • pp.919-928
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    • 2012
  • The applications of computers and communication system and network technologies in nuclear power plants have expanded recently. This application of digital technologies to the instrumentation and control systems of nuclear power plants brings with it the cyber security concerns similar to other critical infrastructures. Cyber security risk assessments for digital instrumentation and control systems have become more crucial in the development of new systems and in the operation of existing systems. Although the instrumentation and control systems of nuclear power plants are similar to industrial control systems, the former have specifications that differ from the latter in terms of architecture and function, in order to satisfy nuclear safety requirements, which need different methods for the application of cyber security risk assessment. In this paper, the characteristics of nuclear power plant instrumentation and control systems are described, and the considerations needed when conducting cyber security risk assessments in accordance with the lifecycle process of instrumentation and control systems are discussed. For cyber security risk assessments of instrumentation and control systems, the activities and considerations necessary for assessments during the system design phase or component design and equipment supply phase are presented in the following 6 steps: 1) System Identification and Cyber Security Modeling, 2) Asset and Impact Analysis, 3) Threat Analysis, 4) Vulnerability Analysis, 5) Security Control Design, and 6) Penetration test. The results from an application of the method to a digital reactor protection system are described.

Somatotype of Women's Upper Body through a Development Figure of the Surface of the Body (체표면 전개도에 의한 여자 상반신의 유형분석 -20대 여성을 중심으로-)

  • 최은주
    • Journal of the Korean Society of Clothing and Textiles
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    • v.20 no.1
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    • pp.170-182
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    • 1996
  • The purpose of this study is to classify the upper body of women into several kind.; of somatotypes, using the method of Surgical Tape and making their shells. The subjects are 50 females 20 to 29 years-old. Fifty-one anthropometric data are measured per shell of body surface : eight somatotype factors are obtained through principal component analysis and orthogonal rotation by the method of Varimax, Somatotype of women's upper body is achieved by cluster analysis, using the standardized factor score a.: an independent variable and the FASTCLUS of SAS by Kmeans. The results are as follows : 1. The number of the factors which explain the somatotype is eight and these factors comprise 81.63 percent of total variance. Factor 1 related to the degree of fatness in the front of upper body Factor 2 related to the degree of fatness in the back of upper body Factor 3 . related to the length of the upper body Factor 4 : related to the type of the upper chest over the chest circmference line Factor 5 : related to the armhole and neck Factor 6 : related to the type of lower chest under the chest circumference line Factor 7: related to the part of the back shoulder Factor 8: related to the depth of front neck and side dart of front independently 2. Cluster analysis results in classification of upper body into five clusters. Cluster 1 : the of circumference i.: lager and that of length is longer than the average The louver part of chest is the lagest and widest among surface areas. Cluster 2 : the circumference is the smallest , the length and surface area are small. The upper and lower chest is small Cluster 3 : the length and surface area are the smallest , the circumference is average. The body line (silhouette) from chest to waist is curved slightly.

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Rad51 Regulates Reprogramming Efficiency through DNA Repair Pathway

  • Lee, Jae-Young;Kim, Dae-Kwan;Ko, Jeong-Jae;Kim, Keun Pil;Park, Kyung-Soon
    • Development and Reproduction
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    • v.20 no.2
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    • pp.141-147
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    • 2016
  • Rad51 is a key component of homologous recombination (HR) to repair DNA double-strand breaks and it forms Rad51 recombinase filaments of broken single-stranded DNA to promote HR. In addition to its role in DNA repair and cell cycle progression, Rad51 contributes to the reprogramming process during the generation of induced pluripotent stem cells. In light of this, we performed reprogramming experiments to examine the effect of co-expression of Rad51 and four reprogramming factors, Oct4, Sox2, Klf4, and c-Myc, on the reprogramming efficiency. Co-expression of Rad51 significantly increased the numbers of alkaline phosphatase-positive colonies and embryonic stem cell-like colonies during the process of reprogramming. Co-expression ofRad51 significantly increased the expression of epithelial markers at an early stage of reprogramming compared with control cells. Phosphorylated histone H2AX (${\gamma}H2AX$), which initiates the DNA double-strand break repair system, was highly accumulated in reprogramming intermediates upon co-expression of Rad51. This study identified a novel role of Rad51 in enhancing the reprogramming efficiency, possibly by facilitating mesenchymal-to-epithelial transition and by regulating a DNA damage repair pathway during the early phase of the reprogramming process.

What factors reduce the yield potentiality in high-yielding rice?

  • Kobata, Tohru;Yoshida, Haruka;Masiko, Uukina;Honda, Tohru;Ishi, Hibiki;Iwasaki, Hiroyuki
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2017.06a
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    • pp.19-19
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    • 2017
  • The indica ${\times}$ japonica rice (Oryza sativa L.) cultivars released in Japan since 1980 are high-yielding. However, occasionally in these cultivars their high yield potentials cannot be realized, particularly depending on climate conditions. The objectives of this study were to identify the reason for yield instability and the critical yield component factor causing lower grain yield in these high-yielding cultivars. Standard-yield japonica, high-yielding japonica-dominant, and indica-dominant cultivars were grown in western Japan. Rough grain yield (RY) in these high-yielding cultivars ranged from 450 to $980g\;m^{-2}$, and was positively correlated with potential grain yield (PRY). By fluctuations of solar radiation, RY changed with spikelet number (SNO), and SNO was correlated with cumulative radiation during the panicle formation period of 30 days before heading. Even if higher SNO was achieved under higher radiant conditions, RY was lower than PRY. The lower grain-filling in plants bearing higher SNO resulted from a lower filling percentage of spikelets (%F, RY/PRY), and %F was strongly correlated with spikelet fertility (%S) across all cultivars. %S was highly influenced by cumulative radiation per PRY during pollen development and establishment around heading. Inhibition of assimilation by leaf removal lowered %S. Conversely, stem thinning and removal of upper panicles around heading increased %S in spikelets of the lower part of the panicle in which sterility was higher. These results suggest that limitation of assimilate-supply due to low irradiance at the spikelet-formation and flowering stages restrains the potential of the high-yielding cultivars, depending on reduction of SNO and %S, respectively.

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Cost Structure of Medical Services in Korean National Health Insurance (건강보험 의료행위의 비용구조)

  • Oh, Young-Sook;Kang, Gil-Won
    • Health Policy and Management
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    • v.20 no.2
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    • pp.40-52
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    • 2010
  • Health insurance fees are set by relative value scales and conversion factors. Since 2008 the conversion factor has been classified into 7 according to the provider type, and a separate contract has been made respectively. As such classification of the conversion factor reflects only the different characteristics of providers, however, further classification to reflect the different cost structures of providers is proposed. Cost varies according to the type of not only providers but also services each provider supply. In fact different cost structures of providers are the result of their different services. This study analyzed the cost structure of medical services to propose a new approach to the classification of the conversion factor. This study analyzed the cost structure of medical services using cost data constructed in the revision study of relative value scales. The cost data consist of doctor's fee, support staff's fee, cost of medical equipments, cost of medical supplies and indirect cost. The proportion of each cost component to the total cost was analyzed in terms of service department and service type. 72 service groups are defined in terms of the combination of service department and service type. Through cluster analysis, 72 service groups were reduced into 7 clusters each of which has a similar cost structure. Conversion factor is contracted annually to reflect the change in the cost of providing medical services. So the classification of conversion factor has to be based on the cost structures of medical services, not the characteristics of providers. Service clusters derived in this study can be used as a new classification for health insurance fee contract.

Development of a Computer Program for Thermal Sizing of a Copper Bonded Steam Generator (구리밀봉 증기발생기의 열적크기 계산을 위한 프로그램 개발)

  • 김의광;김연식;어재혁;김성오;백병준
    • Journal of Energy Engineering
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    • v.12 no.2
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    • pp.84-92
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    • 2003
  • A one-dimensional thermal-hydraulic analysis computer program is developed for thermal sizing of a copper bonded steam generator. It is assumed that the conduction heat transfer of copper region between the hot side and the cold side tube is one-dimensional and its thermal resistance is derived as a function of a tube pitch. The flow regions of the water/steam side are divided into four regions: subcooled, saturated, film boiling, and super-heated. The number of tube selected ranges from 250 to 3500 and the pitch to tube diameter (P/D) ratios are 1.4, 1.6 and 1.8 for the parametric study calculation. The calculation results showed that when the number of tube was 2500, the length of the heating tube was about 12 m and the outside diameter of the steam generator was about 3 m. If the P/D ratio increases, the thermal resistance of copper component also increases, however the length of the heating tube is not so much increased.

The Analysis of Optimal Site Condition for Photovoltaic System and Green Roof Planting through Sunlight Component Simulation of Rooftop Area (옥상공간의 태양광 자원 해석을 통한 PV 시스템 및 녹화식재에 대한 적지조건분석)

  • Kim, Tae Han;Park, Dae Keun;Kwan, Ji Young
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.16 no.4
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    • pp.27-40
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    • 2013
  • These day morden cities have serious climatic problems due to enviornmental load caused by excessive development of urbanization. As technological improvement to answer to various ecological disasters and climate changes are also called on the field of construction, inter-disciplinary studies linked to the estabilishment of sustainable energy generation systems and enviornmental control is needed in a consilient point of view. This study aims to analyse optimal site conditions for photovoltaic system and green roof planting through solar radiation simulation in a integrated perspective. In so doing, it seeks to proffer basic study for developing a sound use of roof area that is sustainable in environmental and resources aspects. A computer simulation showed that, in the case of total seasonal solar radiation, summer season resulted 312.5kWh in 35% of total annual solar radiation. This season indicated the lowest radiation rate of the year for direct sunlight in 45.8% of total seasonal solar radiation. Due to such solar radiation simulation, at the largest optimal planting area, Glechoma hederacea var. longituba secured $719.16m^2$ of gross roof area.