• Genomics & Informatics
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• 제18권1호
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• pp.11.1-11.3
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• 2020

In genome-wide association studies, pathway-based analysis has been widely performed to enhance interpretation of single-nucleotide polymorphism association results. We proposed a novel method of hierarchical structural component model (HisCoM) for pathway analysis of common variants (HisCoM for pathway analysis of common variants [HisCoM-PCA]) which was used to identify pathways associated with traits. HisCoM-PCA is based on principal component analysis (PCA) for dimensional reduction of single nucleotide polymorphisms in each gene, and the HisCoM for pathway analysis. In this study, we developed a HisCoM-PCA software for the hierarchical pathway analysis of common variants. HisCoM-PCA software has several features. Various principle component scores selection criteria in PCA step can be specified by users who want to summarize common variants at each gene-level by different threshold values. In addition, multiple public pathway databases and customized pathway information can be used to perform pathway analysis. We expect that HisCoM-PCA software will be useful for users to perform powerful pathway analysis.

• Bulletin of the Korean Chemical Society
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• 제24권9호
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• pp.1345-1350
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• 2003

Principal component analysis based two-dimensional (PCA-2D) correlation analysis is applied to FTIR spectra of polystyrene/methyl ethyl ketone/toluene solution mixture during the solvent evaporation. Substantial amount of artificial noise were added to the experimental data to demonstrate the practical noise-suppressing benefit of PCA-2D technique. 2D correlation analysis of the reconstructed data matrix from PCA loading vectors and scores successfully extracted only the most important features of synchronicity and asynchronicity without interference from noise or insignificant minor components. 2D correlation spectra constructed with only one principal component yield strictly synchronous response with no discernible a asynchronous features, while those involving at least two or more principal components generated meaningful asynchronous 2D correlation spectra. Deliberate manipulation of the rank of the reconstructed data matrix, by choosing the appropriate number and type of PCs, yields potentially more refined 2D correlation spectra.

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2002년도 봄 학술발표논문집 Vol.29 No.1 (A)
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• pp.247-249
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• 2002

본 논문에서는 주성분 분석(principal component analysis; 이하 PCA) 및 독립성분분석(independent component analysis; 이하 ICA)을 이용, 이차원 영상을 분류하여 다중해상도에서 영상간의 거리를 측정하여 PCA 와 ICA 중에서 어느 것이 영상간의 상대적 식별을 용이하게 하는지 모의 실험을 통하여 확인하고자 한다. 모의 실험 결과로부터, ICA가 PCA에 비하여 영상간의 상대적 식별이 용이하여 빨리 수렴이 되는 것을 모의 실험을 통하여 확인하였다.

• 한국콘텐츠학회:학술대회논문집
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• 한국콘텐츠학회 2003년도 추계종합학술대회 논문집
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• pp.213-217
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• 2003

이 논문에서는 MLP(Multilayer Perceptron)가 지닌 잡음 강건성에 대한 통계학적 분석을 하였다. 또한, MLP의 잡음 강건성을 향상시키기 위한 선형적 전처리 단계로써, ICA(independent component analysis)와 PCA(principle component analysis)를 고려하여, 이들이 지닌 잡음처리 효과를 분석한후, MLP와 접목시 나타나는 잡음 강건성의 향상 여부를 필기체 숫자 인식의 시뮬레이션으로 확인하였다.

• 한국통계학회:학술대회논문집
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• 한국통계학회 2004년도 학술발표논문집
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• pp.79-84
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• 2004

We use principal component analysis (PCA) to identify exons of a gene and further analyze their internal structures. The PCA is conducted on the short-time Fourier transform (STFT) based on the 64 codon sequences and the 4 nucleotide sequences. By comparing to independent component analysis (ICA), we can differentiate between the exon and intron regions, and how they are correlated in terms of the square magnitudes of STFTs. The experiment is done on the gene F56F11.4 in the chromosome III of C. elegans. For this data, the nucleotide based PCA identifies the exon and intron regions clearly. The codon based PCA reveals a weak internal structure in some exon regions, but not the others. The result of ICA shows that the nucleotides thymine (T) and guanine (G) have almost all the information of the exon and intron regions for this data. We hypothesize the existence of complex exon structures that deserve more detailed analysis.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2018년도 학술발표회
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• pp.276-276
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• 2018

In this paper the potential of the Principle Component Analysis(PCA) technique that can be used to detect leaks in water pipe network blocks was evaluated. For this purpose the PCA was conducted to evaluate the relevance of the calculated outliers of a PCA model utilizing the recorded pipe flows and the recorded pipe leak incidents of a case study water distribution system. The PCA technique was enhanced by applying the computational algorithms developed in this study. The algorithms were designed to extract a partial set of flow data from the original 24 hour flow data so that the variability of the flows in the determined partial data set are minimal. The relevance of the calculated outliers of a PCA model and the recorded pipe leak incidents was analyzed. The results showed that the effectiveness of detecting leaks may improve by applying the developed algorithm. However, the analysis suggested that further development on the algorithm is needed to enhance the applicability of the PCA in detecting leaks in real-world water pipe networks.

• 한국환경과학회:학술대회논문집
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• 한국환경과학회 2003년도 International Symposium on Clean Environment
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• pp.33-36
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• 2003

Principal component analysis (PCA) was used to improve image classification by the unsupervised classification techniques, the K-means. To do this, I selected a Landsat TM scene of Jeju Island, Korea and proposed two methods for PCA： unstandardized PCA (UPCA) and standardized PCA (SPCA). The estimated accuracy of the image classification of Jeju area was computed by error matrix. The error matrix was derived from three unsupervised classification methods. Error matrices indicated that classifications done on the first three principal components for UPCA and SPCA of the scene were more accurate than those done on the seven bands of TM data and that also the results of UPCA and SPCA were better than those of the raw Landsat TM data. The classification of TM data by the K-means algorithm was particularly poor at distinguishing different land covers on the island. From the classification results, we also found that the principal component based classifications had characteristics independent of the unsupervised techniques (numerical algorithms) while the TM data based classifications were very dependent upon the techniques. This means that PCA data has uniform characteristics for image classification that are less affected by choice of classification scheme. In the results, we also found that UPCA results are better than SPCA since UPCA has wider range of digital number of an image.

• 한국지능시스템학회:학술대회논문집
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• 한국퍼지및지능시스템학회 2000년도 추계학술대회 학술발표 논문집
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• pp.305-309
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• 2000

In this paper, we presents a new methodology for face recognition after analysing conventional ICA(Independent Component Analysis) based approach. In the literature we found that ICA based methods have followed the same procedure without any exception, first PCA(Principal Component Analysis) has been used for feature extraction, next ICA learning method has been applied for feature enhancement in the reduced dimension. However, it is contradiction that features are extracted using higher order moments depend on variance, the second order statistics. It is not considered that a necessary component can be located in the discarded feature space. In the new methodology, features are extracted using the magnitude of kurtosis(4-th order central moment or cumulant). This corresponds to the PCA based feature extraction using eigenvalue(2nd order central moment or variance). The synergy effect of PCA and ICA can be achieved if PCA is used for noise reduction filter. ICA methodology is analysed using SVD(Singular Value Decomposition). PCA does whitening and noise reduction. ICA performs the feature extraction. Simulation results show the effectiveness of the methodology compared to the conventional ICA approach.

• 한국정보통신학회논문지
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• 제14권5호
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• pp.1093-1102
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• 2010

주성분 분석(PCA)은 데이터의 차원을 줄이면서 최대의 데이터 변이를 보존하는 기법으로 차원 축소나 피처 추출을 위해 널리 사용되고 있다. 하지만 PCA는 잡음에 민감한 단점이 있으며, 이러한 잡음 민감성을 해결하기 위해 여러 가지 PCA 변형이 제안되었다. 그 중 robust fuzzy PCA(RF-PCA)는 퍼지 소속도를 사용하여 잡음의 영향을 효과적으로 줄일 수 있음이 입증되었다. 하지만 RF-PCA 역시 몇 가지 문제점이 있고, 수렴성이 그 중 하나이다. RF-PCA는 소속도와 주성분을 갱신할 때 서로 다른 목적 함수를 사용하므로 수렴 속도가 느리고 구해지는 해가 국부 최적 해임을 보장하지 않는다. 이 논문에서는 RF-PCA의 문제점을 해결하기 위해 하나의 목적 함수를 이용해 소속도와 주성분을 갱신할 수 있는 방법을 제안한다. 제안한 방법, RF-PCA2는 반복 최적화를 이용함으로써 국부 최적해에 수렴함을 보장하며, RF-PCA에 비해 빠른 수렴 속도를 가지고, 잡음 민감성이 줄어든다. 이러한 사실들은 실험 결과를 통해 확인할 수 있다.

• 한국컴퓨터정보학회논문지
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• 제16권4호
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• pp.15-22
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• 2011

주성분 분석(PCA)은 데이터의 차원을 줄이면서 최대의 데이터 변이를 보존하는 기법으로 차원 축소나 특징 추출을 위해 널리 사용되고 있다. 하지만 PCA는 잡음에 민감하며 가우스 분포에 대하여만 유효하다는 단점이 있다. 잡음 민감성의 개선을 위해 다양한 방법이 제시되었고 그 중 퍼지 소속도를 이용한 반복적 최적화 기법인 RF-PCA2가 다른 방법에 비해 우수한 성능을 보였다. 하지만 RF-PCA2는 가우스 분포에만 사용할 수 있는 선형 알고리듬이라는 한계가 있다. 이 논문에서는 RF-PCA2와 커널 주성분 분석(kernel PCA, K-PCA)을 결합하여 가우스 분포 이외의 분포들도 다룰 수 있는 비선형 알고리듬인 improved robust kernel fuzzy PCA (RKF-PCA2)를 제안한다. RKF-PCA2는 RF-PCA2 알고리듬의 잡음 강건성과K-PCA의비선형성을 통해 기존알고리듬에 비해 잡음민감성이 적으며 가우스분포 한계를 효과적으로 극복할 수 있다. 이러한 사실은 실험 결과를 통해 확인할 수 있다.