• Transactions of the Korean Society of Mechanical Engineers B
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• v.41 no.4
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• pp.257-268
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• 2017

This paper proposes an efficient two-dimensional simulation model for solid oxide fuel cells (SOFCs) based on the electrochemical effectiveness model. The effectiveness model is known to accurately predict the current generation performance of SOFC electrodes, by considering the complex reaction/transport processes that occur within thin active functional layers near the electrolyte. After validation tests, the two-dimensional simulation model was used to calculate the distribution of current density and oxygen concentration transverse to the flow channel in anode-supported SOFCs, with which the oxygen depletion characteristics were investigated in detail. In addition, simulations were also conducted to determine the minimum number of grids required in the transverse direction to efficiently obtain accurate results.

• Journal of Information Processing Systems
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• v.8 no.3
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• pp.495-520
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• 2012

A secure Electronic Payment System (EPS) is essential for the booming online shopping market. A successful EPS supports the transfer of electronic money and sensitive information with security, accuracy, and integrity between the seller and buyer over the Internet. SET, CyberCash, Paypal, and iKP are the most popular Credit Card-Based EPSs (CCBEPSs). Some CCBEPSs only use SSL to provide a secure communication channel. Hence, they only prevent "Man in the Middle" fraud but do not protect the sensitive cardholder information such as the credit card number from being passed onto the merchant, who may be unscrupulous. Other CCBEPSs use complex mechanisms such as cryptography, certificate authorities, etc. to fulfill the security schemes. However, factors such as ease of use for the cardholder and the implementation costs for each party are frequently overlooked. In this paper, we propose a Web service based new payment system, based on ANSI X9.59-2006 with extra features added on top of this standard. X9.59 is an Account Based Digital Signature (ABDS) and consumer-oriented payment system. It utilizes the existing financial network and financial messages to complete the payment process. However, there are a number of limitations in this standard. This research provides a solution to solve the limitations of X9.59 by adding a merchant authentication feature during the payment cycle without any addenda records to be added in the existing financial messages. We have conducted performance testing on the proposed system via a comparison with SET and X9.59 using simulation to analyze their levels of performance and security.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.10 no.1
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• pp.18-26
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• 1998

In order to find out hydrodynamic changes due to huge complex constructions in the Keum River Estuary, two-dimensional finite element model is applied. Model results show that gate closing of the estuary dam yields tide amplifications at Kunsan Inner Port to 17 cm and 6 cm of M$_2$ and S$_2$, while 5 cm and 3 cm of amplification at Kunsan Outer Port. Tidal currents in the main channel due to stepwise flow-guide dikes construction have been simulated and show that dynamic equilibrium bottom shear stress is 0.4 N/m$\^$2/ on this Keum River Estuary. Sedimentation rates R have correlation with maximum bottom shear stress (equation omitted), R=-0.37-0.40 ln $\tau$.

• The Korean Journal of Physiology and Pharmacology
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• v.2 no.3
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• pp.287-295
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• 1998

Diazepam is known to have cardiovascular depressive effects through a combined action on benzodiazepinergic receptor and the GABA receptor-chloride ion channel complex. Moreover, it is known that barbiturates also have some cardiovascular regulatory effects mediated by the central GABAergic system. Therefore, this study was undertaken to delineate the regulatory actions and interactions of these systems by measuring the responses of the cardiovascular system and renal nerve activity to muscimol, diazepam and pentobarbital, administered intracerebroventricularly in rabbits. When muscimol $(0.03{\sim}0.3\;{\mu}\;g/kg)$, diazepam $(10{\sim}100\;{\mu}\;g/kg)$ and pentobarbital $(1{\sim}10\;{\mu}\;g/kg)$ were injected into the lateral ventricle of the rabbit brain, there were similar dose-dependent decreases in blood pressure (BP) and renal nerve activity (RNA). The relative potency of the three drugs in decreasing BP and RNA was muscimol ＞ pentobarbital ＞ diazepam. Muscimol and pentobarbital also decreased the heart rate in a dose-dependent manner; however, diazepam produced a trivial, dose-independent decrease in heart rate. Diazepam $(30\;{\mu}g/kg)$ augmented the effect of muscimol $(0.1\;{\mu}g/kg)$ in decreasing blood pressure and renal nerve activity, but pentobarbital $(3\;{\mu}g/kg)$ did not. Bicuculline $(0.5\;{\mu}g/kg)$, a GABAergic receptor blocker, significantly attenuated the effect of muscimol in decreasing BP and RNA, either alone or with diazepam, and that of pentobarbital in decreasing BP and RNA, either alone or with muscimol. We inferred that the central benzodiazepinergic and barbiturate systems help regulate peripheral cardiovascular function by modulating the GABAergic system, which adjusts the output of the vasomotor center and hence controls peripheral sympathetic tone. Benzodiazepines more readily modulate the GABAergic system than barbiturates.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.50 no.3
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• pp.233-243
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• 2014

The difference of mooring tension by type of buoy was investigated in the circulating water channel and the wave tank for deducting the most stable buoy from the current and the wave condition. 5 types of buoy made up of short cylinder laid vertically (CL-V), short cylinder laid horizontally (CL-H), capsule (CS), sphere (SP) and long cylinder (CL-L) were used for experiments. A mooring line and a weight were connected with each buoy. A tensile gauge was installed between a mooring line and a weight. All buoy's mooring tension was measured at the same time for the wave test with periods of 1.5~3.0 sec and wave heights of 0.1~0.3 m, and the current test with flow speeds of 0.2~1.0 m/sec. As a result, the order of tension value in the wave test was CL-H > CL-V > SP > CS > CL-L. In the current test CL-V and CL-H were recorded in the largest tension value, whereas SP has the smallest tension value. So it seems that SP buoy is the most effective in the location affected by fast current. CS is predicted to be suitable for a location that influence of wave is important more than that of current if practical use in the field is considered. And it was found that the difference of mooring tension among buoys in wave is related to the product of the cross sectional area and the drag coefficient for the buoy's bottom side in high wave height. The factor for the current condition was not found. But it was supposed to be related to complex factors like a dimension and a shape by buoy's posture to flow.

• Journal of the Society of Naval Architects of Korea
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• v.31 no.4
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• pp.66-72
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• 1994

For the reliable prediction of maneuverability of a ship, lots of captive model tests have been carried out for over 10 years. But the parameters appearing in the mathematical model are so versatile and showing complex characteristics, and it is still hard to establish the useful formulae that we can adopt directly in the design stage. In this paper, the most important parameters in the mathematical model. i.e.($1-\omega_P$) the effective wake fraction at propeller, and $\delta_R(\beta_R)$), the effective rudder inflow angles are investigated by the captive model tests at the circulating water channel. The model is tested at designed speed and at low speed, and the drafts at both full load and ballast load conditions are taken. Propeller thrusts and rudder normal forces are measured at the given drift angle and propeller revolution. These forces are used for the analysis of the effective flow velocity or flow direction, to the propeller or rudder.

• Archives of Pharmacal Research
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• v.18 no.2
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• pp.105-112
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• 1995

In ordedr to gain insight into the mechanisms byl which erythropoietin promotes erythropoiesis, effects of various inhibitors on the erythropoietin-propmoted differentiation of erythroid progenitor cells and on the erythroid progenitor cells and on the erythropoietin-promoted $Ca^{++}$ uptake in the progenitor cells were determined, and the relationship between the inhibitory activity of each inhibitor cells were determined, and he relationship between the inhibitory activity of each inhibitor toward the differentiation and channel blocker (varapamil), a $Ca^{++}$ chelator (EDTA) and a protein kinase C inhibitor (stauroporine). All of these agents inhibited both the erythropoietin-mediated differentiation of the erythroid progenitor cells, as determined by the incroporation of $^{59}Fe$ into heme, and $Ca^{++}$ uptake in a concentrtion dependent manner. In the cases of varapamil and EDTA, the half-miximal inhibitory concentration $(IC_{50})$ values for differentiation of the progenitor cells may be theconsequence of the inhibition of the $Ca^{++}$ uptake in a concentration dependent manner. In the cases of varapamil and EDTA, the half-miximal inhibitory concentration dependent manner. In the cases of verapamil and EDTA, the half-miximal inhibitory concentration $(IC_{50})$ values for differentiation of the progenitor cells may be the consequence of the inhibition of the $Ca^{++}$ uptake by the inhibitor. On the other hand, in the cases of genistein and stauroporine, the $IC_{50}$ values for inhibition of differentitation were significantly different from that for inhibition of $Ca^{++}$uptake. These results suggest that the mechanism of inhibition of differentiation by these two inhibitors in complex. However, taken all together, the above results support the proposition that $Ca^{++}$ uptake may play a role in the erythropoietin-mediated differentiation of erythoid progenitor cells.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.1
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• pp.470-476
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• 2019

The braking force for a train is generally provided by compressed air. The pressure valve system that is used to apply appropriate braking forces to trains has a complex flow circuit. It is possible to make a channel shape that can increase the flow efficiency by 3D printing. There are restrictions on the flow shape design when using general machining. Therefore, in this study, the compressed air flow was analyzed in a pressure valve system by comparing flow paths made with conventional manufacturing methods and 3D printing. An analysis was done to examine the curvature magnitude of the flow path, the diameter of the flow path, the magnitude of the inlet and reservoir pressure, and the initial temperature of the compressed air when the flow direction changes. The minimization of pressure loss and the uniformity of the flow characteristics influenced the braking efficiency. The curvilinear flow path made through 3D printing was advantageous for improving the braking efficiency compared to the rectangular shape manufactured by general machining.

• Journal of Aerospace System Engineering
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• v.13 no.2
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• pp.19-25
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• 2019

To detect the impact location of a structure, the authors' group conducted a study on piezoelectric paint sensor. The piezoelectric paint sensors are used for impact detection due to their inherent characteristics: sensitivity to high-frequency signal and impact. Additionally, the paint sensor can be applied on curved and complex structures where ceramic sensor would not be applicable. Moreover it is a self-powered sensor therefore no need for an external power source. For impact localization, mosaic pattern electrodes were coated on the specimen and the impact signal obtained from any part of the electrode where the impact occurred. If we more precise impact localization is required, the electrodes should be divided into more parts and impact data acquisition conducted in all the points of the electrode. In this paper, we developed a light, cheap and simple multi-channel data acquisition system to aid in data gathering. In total four channels data acquisition have been tested using the ARM Cortex-M3.

• BMB Reports
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• v.54 no.9
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• pp.464-469
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• 2021

Cardiomyocyte differentiation occurs through complex and finely regulated processes including cardiac lineage commitment and maturation from pluripotent stem cells (PSCs). To gain some insight into the genome-wide characteristics of cardiac lineage commitment, we performed transcriptome analysis on both mouse embryonic stem cells (mESCs) and human induced PSCs (hiPSCs) at specific stages of cardiomyocyte differentiation. Specifically, the gene expression profiles and the protein-protein interaction networks of the mESC-derived platelet-derived growth factor receptor-alpha (PDGFRα)⁺ cardiac lineage-committed cells (CLCs) and hiPSC-derived kinase insert domain receptor (KDR)⁺ and PDGFRα⁺ cardiac progenitor cells (CPCs) at cardiac lineage commitment were compared with those of mesodermal cells and differentiated cardiomyocytes. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway analyses revealed that the genes significantly upregulated at cardiac lineage commitment were associated with responses to organic substances and external stimuli, extracellular and myocardial contractile components, receptor binding, gated channel activity, PI3K-AKT signaling, and cardiac hypertrophy and dilation pathways. Protein-protein interaction network analysis revealed that the expression levels of genes that regulate cardiac maturation, heart contraction, and calcium handling showed a consistent increase during cardiac differentiation; however, the expression levels of genes that regulate cell differentiation and multicellular organism development decreased at the cardiac maturation stage following lineage commitment. Additionally, we identified for the first time the protein-protein interaction network connecting cardiac development, the immune system, and metabolism during cardiac lineage commitment in both mESC-derived PDGFRα⁺ CLCs and hiPSC-derived KDR⁺PDGFRα⁺ CPCs. These findings shed light on the regulation of cardiac lineage commitment and the pathogenesis of cardiometabolic diseases.