• 대한핵의학회지
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• 제32권1호
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• pp.99-108
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• 1998

Intraperitoneal administration of radioisotopes is suggested to treat the metastatic ovarian cancer in the peritoneal cavity. Administering beta-emitting radioisotopes into the peritoneal cavity allows the maximum energy delivery to the cancerous cells of the peritoneal wall surface while sparing the normal cells located in deep site of the peritoneal wall. In this study, dose estimates of the peritoneal wall are provided to be used for prescribing the amount of $^{166}Ho$-chitosan complex administered. The $^{166}Ho$-chitosan complex diffused in the peritoneal fluid may attach to the peritoneal wall surface. The attachment fraction of $^{166}Ho$-chitosan complex to the peritoneal wall surface is obtained by simulating the ascites with Fischer rats. Both volume source in the peritoneal fluid and the surface source over the peritoneal wall surface are counted for the contribution to the peritoneal wall dose. The Monte Carlo code EGS4 is used to simulate the energy transfer of the beta particles emitted from $^{166}Ho$. A plane geometrical model of semi-infinite volume describes the peritoneal cavity and the peritoneal wall. A semi-infinite plane of $10{\mu}m$ in thickness at every 1 mm of depth in the peritoneal wall is taken as the target in dose estimation. Greater than 98 percents of attachment fraction has been observed from the experiments with Fischer rats. Given $1.3{\mu}Ci/cm^2$ and $2.4{\mu}Ci/ml$ of uniform activity density, absorbed dose is 123 Gy, 8.59 Gy, 3.00 Gy, 1.03 Gy, and .327 Gy at 0 mm, 1 mm, 2 mm, 3 mm, and 4 mm in depth to the peritoneal wall, respectively.

• 한국전자파학회논문지
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• 제25권8호
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• pp.872-878
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• 2014

본 논문은 새로운 캐비티 공진기 구조를 이용한 반고체 상태 물질의 복소 비유전율 측정 방법을 제안하고 있다. 윗면에 개구면이 존재하고, Ground 판이 분리되어 있는 구조를 이용하여 반고체 상태 물질도 캐비티 내부에 위치할 수 있도록 했다. 공진주파수의 변화와 Critical-Points Method를 이용해 실험적으로 증류수와 0.9 % 식염수의 복소 비유전율을 측정하였으며, 측정값을 Cole-Cole Equation을 통해 이론값과 비교했다.

• 한국전산유체공학회지
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• 제13권1호
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• pp.35-40
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• 2008

Generally flight vehicles have many cavities such as wheel wells, bomb bays and windows on their external surfaces and the flow around these cavities makes separation, vortex, shock and expansion waves, reattachment and other complex flow phenomenon. The flow around the cavity makes abnormal and three-dimensional noise and vibration even thought the aspect ratio (L/D) is small. The cavity giving large effects to the flow might make large noise, cause structural damage or breakage, harm the aerodynamic performance and stability, or damage the sensitive devices. In this study, numerical analysis was performed for cavity flows by the unsteady compressible three dimensional Reynolds-Averaged Navier-Stokes (RANS) equations with Wilcox's $\kappa-\omega$ turbulence model. The MPI(Message Passing Interface) parallelized code was used for calculations by PC-cluster. The cavity has the aspect ratios of 2.5, 3.5 and 4.5 with the W/D ratio of 2 for three-dimensional cavities. The Sound Pressure Level (SPL) analysis was done with FFT to check the dominant frequency of the cavity flow. The dominant frequencies were analyzed and compared with the results of Rossiter's formula and Ahuja& Mendoza's experimental datum.

• Nuclear Engineering and Technology
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• 제48권1호
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• pp.189-199
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• 2016

Fast neutrons with a broad energy spectrum, with which it is possible to evaluate nuclear data for various research fields such as medical applications and the development of fusion reactors, can be generated by irradiating proton beams on target materials such as beryllium. To generate short-pulse proton beam, we adopted a deflector and slit system. In a simple deflector with slit system, most of the proton beam is blocked by the slit, especially when the beam pulse width is short. Therefore, the available beam current is very low, which results in low neutron flux. In this study, we proposed beam modulation using a buncher cavity to increase the available beam current. The ideal field pattern for the buncher cavity is sawtooth. To make the field pattern similar to a sawtooth waveform, a multiharmonic buncher was adopted. The design process for the multiharmonic buncher includes a beam dynamics calculation and three-dimensional electromagnetic simulation. In addition to the system design for pulsed proton generation, a test bench with a microwave ion source is under preparation to test the performance of the system. The design study results concerning the pulsed proton beam generation and the test bench preparation with some preliminary test results are presented in this paper.

• 대한기계학회논문집B
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• 제26권6호
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• pp.811-816
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• 2002

For the first time, airflow in the nasal cavity of a normal Korean adult is investigated experimentally by PIV measurement. Nasal airflow can be subdivided into two interrelated categories; nasal airflow resistance and heat and mass transfer between the air stream and the walls of the nasal cavity. In this study, thanks to a new method for the model casting by a combination of the rapid prototyping and curing of clear silicone. a transparent rectangular box containing the complex nasal cavity can be made fur PIV experiments. The CBC PIV algorithm is used for analysis. Average and RMS distributions are obtained for inspirational and expiration nasal airflows. Data fer the airflow at the end of meatuses are obtained for the first time. Comparisons between western and Korean nasal airflows are appreciated. Due to the difference in geometry of the frontal part of nasal cavity, the flow near nares shows the difference.

• 한국자동차공학회논문집
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• 제7권6호
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• pp.82-90
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• 1999

Numerical analysis of the three dimensional flow in a bus engine room is carried out through this study. The radiator and the fan modeling rare carried out to simulate the flow in an engine room, and the results are focused on the flow in the cavity located in front of the radiator. The numerical simulation results are compared with the experiment . To improve the cooling performance in the bus engine room, the flow inside the cavity is inspected in detail. The complex flow features are found in this region , and the suggestion are made to improve the radiators cooling performance.

• Structural Engineering and Mechanics
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• 제35권4호
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• pp.409-430
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• 2010

The present paper will be concerned to the investigation of the stress-strain field around the cavity that is loaded or partially loaded at the inner surface by the rotationally symmetric loading. The cavity of the spherical, cylindrical or elliptical shape is situated in a stressed elastic continuum, subjected to the gravitation field. As the contribution to the similar investigations, the paper introduces the new function of loading in the form of the infinite sine series. Besides, in this paper the solution of stresses around an oblong ellipsoid cavity, has been obtained using appropriate curvilinear elliptical coordinates. This analytical approach avoids the solutions of the same problem that lead to expressions that contain rather complex integrations. Thus the presented solutions provide the applicable and explicit expressions for stresses and strains developed in infinite series with easily determinable coefficients by the use of contemporary mathematical packages. The numerical examples are also included to confirm the convergence of the obtained solutions.

• 한국마린엔지니어링학회:학술대회논문집
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• 한국마린엔지니어링학회 2005년도 전기학술대회논문집
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• pp.1149-1154
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• 2005

The finite difference lattice Boltzmann method(FDLBM) is a quite recent approach for simulating fluid flow, which has been proven as a valid and efficient tool in a variety of complex flow problems. It is considered an attractive alternative to conventional FDM and FVM, because it recovers the Navier-Stokes equations and is computationally more stable, and easily parallelizable to simulate for various laminar flows and a direct simulation of aerodynamics sounds. However, the research of a numerical simulation of turbulent flow by FDLBM, which is important to analyze the structure of turbulent flow in engineering fields, is not carried out. In this research, the FDLBM built in the turbulent model is applied, and a flowfield around 2-dimensional square to validate the applied model with 2D9V is simulated. Besides, 2D computation of the cavity noise generated by flow over a cavity at a Mach number of 0.1 and a Reynolds number based on cavity depth of 5000 is calculated. The computation result is well presented a understanding of the physical phenomenon of tonal noise occurred primarily by well-jet shear layer and vortex shedding and an aeroacoustic feedback loop.

• Journal of Pharmaceutical Investigation
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• 제21권4호
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• pp.223-230
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• 1991

The structural specificity and the chemical dynamics between ${\beta}-cyclodextrin$ and aspirin were studied by FT-IR UN, $^1H$ NMR. $^{13}C NMR$. and FAB-MS spectroscopy in solution and solid state, A stable solid inclusion complex was prepared by the recrystallization method, From the spectral changes of the host and guest molecules, orientational preference for binding in the cyclodextrin cavity was determined.

• Journal of applied mathematics & informatics
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• 제7권3호
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• pp.801-812
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• 2000

Two-dimensional slow viscous flow on infinite half-plane past a perpendicular infinite cavity is considered on the basis of the Stokes approximation. Using complex representation of the two-dimensional Stokes flow, the problem is reduced to solving a set of Fredholm integral equations of the second kind. The streamlines and the pressure and vorticity distribution on the wall are numerically determined.