Structure Study of Inclusion Complex of ${\beta}-Cyclodextrin$ and Aspirin

${\beta}$-시클로덱스트린과 아스피린의 포접화합물의 구조에 관한 연구

  • Choi, Hee-Sook (Department of Medicinal Chemistry Purdue University)
  • Published : 1991.12.20

Abstract

The structural specificity and the chemical dynamics between ${\beta}-cyclodextrin$ and aspirin were studied by FT-IR UN, $^1H$ NMR. $^{13}C NMR$. and FAB-MS spectroscopy in solution and solid state, A stable solid inclusion complex was prepared by the recrystallization method, From the spectral changes of the host and guest molecules, orientational preference for binding in the cyclodextrin cavity was determined.

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