• 제목/요약/키워드: Complex I

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카드뮴 이온으로 완전히 치환한 제올라이트 A를 진공 탈수한 구조와 이것에 요오드를 흡착한 결정구조 (Crystal Structures of Vacuum Dehydrated Fully $Cd^{2+}$-Exchanged Zeolite A and of Its iodine Sorption Complex)

  • 장세복;한영욱;김양
    • 한국결정학회지
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    • 제4권2호
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    • pp.54-62
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    • 1993
  • Cd2+ 이온으로 이온교환된 제올라이트 A를 650℃에서 2 ×10-6 T orr의 진공하에서 탈수한 구조 (a:l2.189(2)A)와 이 결정에 요오드가 흡착된 구조 (a:l2.168(2) A)를 21℃에서 입방공간군 Pm3m를 사용하여 단결정 X-선회절법으로 해석하고 정밀화하였다. 탈수한 가In-A의 구조 는 Full-rmoix 최소자승법 정밀화 계산에서 I > 3σ(I)인 186개의 독립반사를 사용하여 최종오차인자를 Rl:0.057, Ra:0.003 까지 정밀화 계산하였고, 이 결정을 요오드로 흡착시킨 구조는 181 개의 독립 반사를 사용하려 Rl = 0.082, R2 : 0.085가지 정밀화시켰다. 두 결정에서 단위세포당 6개의 Cd2+ 이온은 서로 다른 2개의 3회 회전축상에 위치 하고 있었다. 요오드가 흡착된 구조에서 4개의 Cd2+ 이온 은 0(3)의 (111) 평면에서 큰 동공쪽으로 약 0.68(1) A 들어간 I3- 이온이 결합하고 있고 나머지 2개의 Cd2+ 이온은 0(3)의 (111) 평면에서 소다라이트 동공 깊숙히 약 0.68(1) A 들어간 자리에 위치 하고 있다. 단위세포당 약 4개의 I이온이 큰 동공내에 흡착되었다. 각각의 I-는 6-링 Cd2+와 골조의 8-링 산소에 다리를 놓고 있으며 0(1)-I(1)-I(2) 각도는 172(1)˚로써 거의 선형이고 약한 전 하이동 착물을 골조의 8-링 산소와 이루고 있다. 큰 동공 내에 존재하는 I이온은 부분적으로 탈수된 효In-A에서 요오드 증기와 물분자가 반응하여 H+이온과 I-이온이 생성된 후 다시 I이온과 l2 분자와 반응하여 생성되었을 것이다.

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익모초, 어성초, 진피 복합 추출물의 항염증 및 항산화 평가 (Evaluation of Anti-inflammatory and Antioxidant Abilities of Complex Extracts Produced from Leonurus japonicus Houtt., Houttuynia cordata Thunberg, and Citrus unshiu Markovich)

  • 이훈규;지중구
    • 한국응용과학기술학회지
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    • 제40권1호
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    • pp.35-47
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    • 2023
  • 본 연구는 복합추출물(익모초, 어성초, 진피)의 생리활성을 측정하여 식·의약품, 화장품 등의 소재로서의 가능성을 확인하고자 하였다. 복합추출물은 열수 추출하였으며, 세포독성, 항산화, 항염증, MAPKs 등의 평가는 ELISA 및 western blot을 통해 확인하였다. 그 결과, 총 폴리페놀 함량은 35.53±0.48 mg GAE/g, 플라보노이드 함량은 8.18±0.16 mg QE/g으로 나타났으며, DPPH 와 ABTS radical 소거능은 농도 의존적으로 증가하였다. 대조군과 비교하여 세포독성은 400 ㎍/㎖ 농도까지 100% 이상의 생존율이 나타났으며, NO 및 염증성 사이토카인을 유의하게 감소시켰다. 또한, 복합추출물은 MAPKs(ERK, JNK, p38) 단백질 발현을 유의하게 억제시켰다. 이러한 결과는 복합추출물이 산화적 손상 및 염증에 사용될 수 있음을 나타낸다. 따라서 본 연구 결과는 식·의약품, 화장품용 복합소재의의 기초자료로 활용될 수 있을 것이다.

Nutritional Studies on Production of Antibacterial Activity by the Zebra Mussel Antagonist, Pseudomonas fluorescens CL0145A

  • Polanski-Cordovano, Grace;Romano, Lea;Marotta, Lauren L.C.;Jacob, Serena;Hoo, Jennifer Soo;Tartaglia, Elena;Asokan, Deepa;Kar, Simkie;Demain, Arnold L.
    • Journal of Microbiology and Biotechnology
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    • 제23권5호
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    • pp.656-660
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    • 2013
  • Pseudomonas fluorescens strain CL0145A was discovered at the New York State Museum Field Research Laboratory as an effective agent against the environmentally destructive zebra mussel, which has contaminated US waters. Dried cells of the microbe are being commercialized as an environmentally friendly solution to the problem. We found that antibiotic activity against the Gram-positive bacterium Bacillus subtilis is produced and excreted by this strain. We have carried out studies to optimize production of the antibiotic. Studies were begun in a complex corn meal medium. Activity was found in both cells and culture supernates and was maximal after one day of fermentation. Static fermentation conditions were found to be superior to shaken culture. Production of extracellular antibiotic in complex medium was found to be dependent on the content of sucrose and enzyme-hydrolyzed casein. Indeed, production was greater in sucrose plus enzyme-hydrolyzed casein than in the complex medium. Of a large number of carbon sources studied as improvements over sucrose, the best was glycerol. An examination of nitrogen sources showed that production was improved by replacement of enzyme-hydrolyzed casein with soy hydrolysates. Production in the simple glycerol-Hy-Soy medium was not improved by addition of an inorganic salt mixture or by complex nitrogen sources, with the exception of malt extract. In an attempt to keep the medium more defined, we studied the effect of amino acids and vitamins as replacements for malt extract. Of 21 amino acids and 7 vitamins, we found tryptophan, glutamine, biotin, and riboflavin to be stimulatory. The final medium contained glycerol, Hy-Soy, tryptophan, glutamine, biotin, and riboflavin.

공연문화공간의 복합기능 -예르바 부에나 센터와 토가무라 공연문화공간의 사례연구- (A Study on The Multi-Function of The Complex Cultural Center)

  • 김선영
    • 한국실내디자인학회논문집
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    • 제25호
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    • pp.84-93
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    • 2000
  • This study examines multiple functions of the complex cultural center. Recently, the importance of the complex cultural center has been growing, as peoples desire for cultural activities diversified. In order to effectively accommodate the general publics interests in various cultural activities, the complex cultural center tended to be multi-functional. At the same time, I argue that it is necessary to reexamine its functions in terms of how the multi-complex cultural center fits into local environment. Only when both peoples demand and local environment are fully integrated into its design, can the multi-complex cultural center accomplish the goal of multiple functions in a true sense.

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REAL HYPERSURFACES WITH MIAO-TAM CRITICAL METRICS OF COMPLEX SPACE FORMS

  • Chen, Xiaomin
    • 대한수학회지
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    • 제55권3호
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    • pp.735-747
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    • 2018
  • Let M be a real hypersurface of a complex space form with constant curvature c. In this paper, we study the hypersurface M admitting Miao-Tam critical metric, i.e., the induced metric g on M satisfies the equation: $-({\Delta}_g{\lambda})g+{\nabla}^2_g{\lambda}-{\lambda}Ric=g$, where ${\lambda}$ is a smooth function on M. At first, for the case where M is Hopf, c = 0 and $c{\neq}0$ are considered respectively. For the non-Hopf case, we prove that the ruled real hypersurfaces of non-flat complex space forms do not admit Miao-Tam critical metrics. Finally, it is proved that a compact hypersurface of a complex Euclidean space admitting Miao-Tam critical metric with ${\lambda}$ > 0 or ${\lambda}$ < 0 is a sphere and a compact hypersurface of a non-flat complex space form does not exist such a critical metric.

양하지 이상감각을 호소하는 다발신경병증 환자에 대한 침구-한약 복합한방 치료 치험 1례 (A Case Report of Lower Extremity Paresthesia with Polyneuropathy Treated with Traditional Korean Complex Treatment)

  • 이현규;김세원;서유나;배인후;박호정;조기호;문상관;정우상;권승원
    • 대한한방내과학회지
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    • 제41권2호
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    • pp.256-266
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    • 2020
  • Objectives: This report presents the case of a 21-year-old woman with lower extremity paresthesia in both feet due to polyneuropathy. Methods: The patient was treated using a Korean traditional complex treatment approach that included herbal medication, acupuncture, electroacupuncture, and moxibustion. We evaluated the improvements in the pain symptoms in both feet using the numeric rating scale (NRS); we also assessed for gait disturbance and used Digital Infrared Thermographic Imaging (D.I.T.I.) to evaluate minute changes in body temperature in diseased areas. Results: After administering the Korean traditional complex treatment, we observed a decrease in pain levels in both feet based on the NRS scores. We also observed improvements in gait disturbance and D.I.T.I. Conclusions: This case showed that the use of a Korean traditional complex treatment approach, consisting of herbal medication, acupuncture, electroacupuncture, moxibustion, had a positive effect on decreasing polyneuropathy symptoms.

Preparation and Crystal Structures of Silver(I), Mercury(II), and Lead(II) Complexes of Oxathia-Tribenzo-Macrocycles

  • Siewe, Arlette Deukam;Ju, Huiyeong;Lee, Shim Sung
    • Bulletin of the Korean Chemical Society
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    • 제34권3호
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    • pp.725-730
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    • 2013
  • An investigation of the coordination behavior of sulfur-containing mixed-donor tribenzo-macrocycles $L^1-L^3$ ($L^1$: 20-membered $O_3S_2$, $L^2$: 20-membered $O_2S_3$, and $L^3$: 23-membered $O_4S_2$) with $d^{10}$-metal ($Ag^+$, $Hg^{2+}$, and $Pb^{2+}$) salts is reported. The X-ray structures of five complexes (1-5) with different structural types and stoichiometries, including mono- to dinuclear species have been determined. Reactions of $L^2$ and $L^3$ with the silver(I) salts ($PF_6{^-}$ and $SCN^-$) afforded two dinuclear 2:2 (metal-to-ligand) complexes with different arrangements: a sandwich-type cyclic dinuclear complex $[Ag_2(L^2)_2](PF_6)_2{\cdot}3CH_2Cl_2$ (1) and a linear dinuclear complex $[Ag_2(L^3)_2(SCN)_2]$ (2), in which two monosilver(I) complex units are linked by an Ag-Ag contact. Reactions of $L^1$ and $L^2$ with mercury(II) salts ($SCN^-$ and $Cl^-$) gave a mononuclear 1:1 complexes $[Hg(L^1)(SCN)_2]$ (3) and $[Hg(L^2)Cl_2]$ (4) with anion coordination in both cases. $L^2$ reacts with lead(II) perchlorate to yield a mononuclear sandwich-type complex $[Pb(L^2)_2(ClO_4)_2]$ (5), giving an overall metal coordination geometry of eight with a square antiprism arrangement. From these results, the effects of the donor variation and the anioncoordination ability on the resulting topologies of the soft metal complexes are discussed.

환경친화적 산업단지 조성을 위한 환경성 평가 지표개발에 관한 연구 (Development of Environmental Evaluation Indicators for Environmentally Friendly Industrial Estate)

  • 구본학;이은엽
    • 한국환경복원기술학회지
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    • 제3권4호
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    • pp.22-32
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    • 2000
  • Development of index for evaluation of environmental nature and its application for the purpose of construction of industrial complex with environmentally friendly. Industrial complex comes to be recognized as a disgusting zone according to the increasing environment consciousness of residents. And the objection about the exploitation of geographically unwanted land site is increased during development process and it is possible to cause Nimby phenomenon. Therefore, ecology and environment-oriented strategies tends to be adopted for industrial complex development. Furthermore, the maximization of profit mainly directed by enterprises as of today cannot guarantee its future and the efforts of adopting environmental constancy and harmony as a new objective are made progressively. For the development of city and region, in particular such as residence complex, farming and special city, the discussion of environmental consistency, new paradigm with environmentally friendly is briskly under progress, but the relevant discussion for the development of industrial estate is not done so much. Just only few studies are realized from the viewpoint of industrial ecology but its level remains in the understanding of the concepts and presentation of development direction. This study is to prepare for the foundation of the construction of industrial estate with environmentally friendly under the current condition of Korea against coming future environment era and to try to develop of evaluation range and index which are the basis of evaluation of environment. I applied the above evaluation index to the residents of actual industrial estate to understand their consciousness of decreased environment. And I obtained 7 evaluation ranges and 37 evaluation indexes for the relevant residents. Among them, I get the value less than the average in 19 index items. And they represent very sensible reaction about environment pollution including decrease of waste materials. This study has several limits but is meaningful in that the development of evaluation index for environmental nature in industrial complex is done, and that the basic discussion of the plan and design for environmentally friendly industrial estate is made under the above evaluation and that 37 evaluation items are applied to the reality.

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미토콘드리아내 결정함유물의 미세구조 및 면액황금표식법 (Fine Structure and Immunogoldlabeling of Crystalline Inclusion Bodies in Mitochondria)

  • 김수진;이근옥
    • 한국동물학회지
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    • 제31권1호
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    • pp.62-70
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    • 1988
  • 미토콘드리아가 포함하고있는 결정한유물의 미새구조와 면역황금표식법에 의한 분석을 위하여 우심근 세포의 미토콘드리아에서 전자전달체에 관여하는 효소를 분리하였다. 우심근 미토콘드리아에서 분리된 효소는 실험토끼에 주사하여 (복합체I,NADH-conezyme Q reductase; 복합체 III,Ubiquinol-cytochrome-c-oxldoreductase; 복합체 IV, Cytochrome-c-oxidase)들에 대한 면역항체를 얻었다. 이들 면역항체들은 우심근과 정상인의 골격근 미토콘드리아와 미토콘드리아에 결정함유물을 포함하는 mitochondrical myopathy환자의 골격근 미토콘드리아에 반응시켜 황금입자를 표식하고 전자현미경을 이용하여 이들 면역항체반응을 관찰하였다. 미토콘드리아가 포함하는 결정함유물의 미세구조에는 paracrystalline inclusions body와 multilamellar strudure inclusion body그리고 구형결정함유물(globular crystalline inclusions body) 및 윤형구조 (whirl shaped structure)의 크리스테 중심에 있는 구형결정함유물 등의 4종류로관찰되었다. 복합체 I,복합체 Iv의 효소에 대한 항체를 우심근과 정상인 골격근 그리고 mitochondrical myopathy환자의 골격근에 동일한 면역반응을 시켰을때 미토콘드리아 크리스테에 부착하는 황금입자의 표식 정도는 각각의 근조직에서 유사한 반응이 관찰되었다. 복합체 III의 효소에 대한 항체는 우심근과 정상인의 골격근에서는 유사한 반응이 나타났으나 mitochondrical myopathy환자의 골격근에서는 극히 소수의 황금입자가 관찰되었다. 구형결정함유물은 복합체 I,III,IV의 3종류의 효소에 대한 면역반응 결과 황금입자표식은 관찰되지 않았다. 따라서 mitochondrical myopathy환자의 미토콘드리아에는 복합에 III의 효소가 결핍되었으며 구형결정함유물은 전자전달체 효소들인 복합체 I,III,Iv 효소단백질과는 상관없는 물질로 생각된다.

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