• Structural Monitoring and Maintenance
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• v.8 no.4
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• pp.379-402
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• 2021

Traditional approaches for structural health monitoring (SHM) seldom take ambient uncertainty (temperature, humidity, ambient vibration) into consideration, while their impacts on structural responses are substantial, leading to a possibility of raising false alarms. A few predictors model-based approaches deal with these uncertainties through complex numerical models running online, rendering the SHM approach to be compute-intensive, slow, and sometimes not practical. Also, with model-based approaches, the imperative need for a precise understanding of the structure often poses a problem for not so well understood complex systems. The present study employs a data-based approach coupled with Empirical mode decomposition (EMD) to correlate recorded response time histories under varying temperature conditions to corresponding damage scenarios. EMD decomposes the response signal into a finite set of intrinsic mode functions (IMFs). A two-dimensional Convolutional Neural Network (2DCNN) is further trained to associate these IMFs to the respective damage cases. The use of IMFs in place of raw signals helps to reduce the impact of sensor noise while preserving the essential spatio-temporal information less-sensitive to thermal effects and thereby stands as a better damage-sensitive feature than the raw signal itself. The proposed algorithm is numerically tested on a single span bridge under varying temperature conditions for different damage severities. The dynamic strain is recorded as the response since they are frame-invariant and cheaper to install. The proposed algorithm has been observed to be damage sensitive as well as sufficiently robust against measurement noise.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.8
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• pp.3085-3090
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• 2015

The telomeric end structures of the DNA are known to contain tandem repeats of TTAGGG sequence bound with specialised protein complex called the "shelterin complex". It comprises six proteins, namely TRF1, TRF2, TIN2, POT1, TPP1 and RAP1. All of these assemble together to form a complex with double strand and single strand DNA repeats at the telomere. Such an association contributes to telomere stability and its protection from undesirable DNA damage control-specific responses. However, any alteration in the structure and function of any of these proteins may lead to undesirable DNA damage responses and thus cellular senescence and death. In our review, we throw light on how mutations in the proteins belonging to the shelterin complex may lead to various malfunctions and ultimately have a role in tumorigenesis and cancer progression.

• Journal of The Korean Society of Agricultural Engineers
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• v.52 no.3
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• pp.47-55
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• 2010

Investigations on the inundation damage and improvement measures were carried out centering around the protected horticultural complex concentrated in lowlands on the side of Geum river, in Nonsan and Buyeo, Chungnam. Most greenhouses were single-span plastic houses in this area, and tomato, strawberry and watermelon were cultivated mainly. 45.8 % of whole farmhouse were experienced in damage by inundation, and a frequency of the damage was average once in 11 years. The most urgent problem at the greenhouse culture in this area was showed in order of drainage improvement, irrigation water resources and energy saving. Consideration items in drainage improvement project for protected horticulture were showed in order of extending drain pumps, extending drain canals, using concrete flume in drain ditch. It needs to consider systematic plans that can restrain new establishment of greenhouses on the lowland paddy field in drainage area. It is difficult to remove greenhouses which are already established or prohibit cultivation. Therefore we should impose minimum duty items so that greenhouse tillers can cope with inundation. And it is thought that managing agency need to minimize farmers damage by improving drainage ability and introducing maintenance pattern that is different from rice cropping.

• Journal of the Society of Disaster Information
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• v.18 no.4
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• pp.908-921
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• 2022

Purpose: As the connection between physical and non-physical structures in cities is expanding and becoming more complex, the risk of complex disaster which causes damage in a complex way is increasing. Preparing for these complex disasters, it is important to preemptively identify and manage disasters that can develop into complex disasters. Therefore, this study analyzes the disaster types studied as complex disasters by analyzing the trends of domestic and international studies related to complex disasters, and presents the direction of complex disaster management in the future. Method: We first established co-occurrence networks between disaster types based on 993 articles related to complex disasters published in disaster-related journals for the last 20 years (2002-2021). Then, through network analysis, domestic and international complex disaster research trends were compared and analyzed. Result: Research on complex disasters related to storm and flood damage, infrastructure failure and fire was high in domestic studies, and it was analyzed that research on complex disasters related to earthquakes and landslides has recently increased. However, in international studies, the proportion of studies on infrastructure failure along with storm and flood damage and earthquake was high, and various types of disasters such as tsunami and drought appeared. Conclusion: The results of this study are expected to increase the understanding of the trends in complex disaster research and provide suggestions of domestic complex disaster research in the future.

• Journal of Ocean Engineering and Technology
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• v.14 no.1
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• pp.80-87
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• 2000

Despite many combined research efforts outstanding needs exist to develop robust safety-estimation methods for large complex structures. This paper presents a practical damage identification scheme which can be applied to truss structures using only limited modal responses. firstly a theory of pattern recognition (PR) is described. Secondly existing damage-detection algorithms are outlined and a newly-derived algorithms for truss structures. Finally the feasibility of the proposed scheme is evaluated using numerical examples of plane truss structures.

• Molecules and Cells
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• v.42 no.7
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• pp.546-556
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• 2019

Protein phosphatase 4 (PP4) is a crucial protein complex that plays an important role in DNA damage response (DDR), including DNA repair, cell cycle arrest and apoptosis. Despite the significance of PP4, the mechanism by which PP4 is regulated remains to be elucidated. Here, we identified a novel PP4 inhibitor, protein phosphatase 4 inhibitory protein (PP4IP) and elucidated its cellular functions. PP4IP-knockout cells were generated using the CRISPR/Cas9 system, and the phosphorylation status of PP4 substrates (H2AX, KAP1, and RPA2) was analyzed. Then we investigated that how PP4IP affects the cellular functions of PP4 by immunoprecipitation, immunofluorescence, and DNA double-strand break (DSB) repair assays. PP4IP interacts with PP4 complex, which is affected by DNA damage and cell cycle progression and decreases the dephosphorylational activity of PP4. Both overexpression and depletion of PP4IP impairs DSB repairs and sensitizes cells to genotoxic stress, suggesting timely inhibition of PP4 to be indispensable for cells in responding to DNA damage. Our results identify a novel inhibitor of PP4 that inhibits PP4-mediated cellular functions and establish the physiological importance of this regulation. In addition, PP4IP might be developed as potential therapeutic reagents for targeting tumors particularly with high level of PP4C expression.

• Smart Structures and Systems
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• v.24 no.5
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• pp.597-606
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• 2019

Damage detection based on dynamic characteristics of a structure is one of important roles in structural damage identification. It is difficult to detect local structural damage using traditional dynamic experimental methods due to a limited number of sensors used in an experiment. In this work, a non-contact test stand of fan blades is established, and a full-field noncontact test method, combined with three-dimensional digital image correlation, Bayesian operational modal analysis, and damage indices, is used to detect local damage of a fan blade under ambient excitation without use of baseline information before structural damage. The methodology is applied to detect invisible local damage on the fan blade. Such a method has a seemingly high potential as an alternative to detect local damage of blades with complex high-precision surfaces under extreme working conditions because it is a noncontact test method and can be used under ambient excitation without human participation.

• Coupled systems mechanics
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• v.12 no.5
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• pp.445-459
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• 2023

In this study, a cyclic tensile test on a notched butterfly specimen made of woven glass fiber composite was performed on a modified Arcan fixture. During the mechanical test, the sample was monitored with a hybrid stereoscopic system comprised of two visible lights and one infrared camera. The visible light cameras were employed for kinematic measurements using a finite-element-based multiview correlation technique. A semi-hybrid correlation approach was followed, providing Lagrangian temperature fields of the Region of Interest. Due to the complex composite architecture and specimen shape, localized shearing was observed during the tensile loading. Furthermore, asymmetrical damage developed around the notches as revealed by localized strains and thermal hot spots.

• Journal of the Korean Institute of Landscape Architecture
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• v.22 no.3
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• pp.121-135
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• 1994

The Purpose of this study was to obtain data about management of the landscape plants and facility in APT. complex. Because of be completed 2 years ago, landscape plants ware damaged by transplantation and lost the nature tree shape. As well, the management conditions of plants and facility were wholly bad. In details, tree-species consisted of 52 species arbors and 35 species shrubs in APT. complex. The high rank 5 species were planted as main plants. The rates were 45.6-62.8% in arbors and 81.8-97.0% in shrubs. In the degree of tree shape and damage by diseuse and pest, the bad level of 1-2points were ranked highly as 13.9% and 10.4%. In the degree of tree shape and damage by disease and pest, the bad level of 1-2points were showed as 5.1% and 4.7%. In the interview Survey, the main problems of management-maintenance were expressed deficiency of budget, specialist and concern of residents. In the future, methods for the intensive management of APT. complex; First, the management of landscape plants and facility should be attained by a expert and need to establishment of maintenance scheme thoroughly. Above all, for improvement of residential life, we should be lead to convert of a resident recognition in the management -maintenance of exterior space.

• Korean Journal of Remote Sensing
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• v.36 no.5_4
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• pp.1255-1266
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• 2020

In this study, a complex simulation prototype was developed for rapid and accurate prediction of chemical dispersion range in order to reduce human casualties caused by chemical accidents. Complex simulation considered the leakage momentum during the near-field dispersion to take into account the leakage characteristics of the chemical. In the far-distance dispersion process, the wind distribution of the existing model, which was presented uniformly, was improved using weather and topographical information around the accident site, to realize a wind field similar to the actual one. Finally, the damage range was more precise than the existing model in line with the improved near- and far-distance dispersion process. Based on the results of damage range prediction of the complex simulation, it is expected that it will be highly utilized as a system to support policy decision-making such as evacuation and return of residents after a chemical accident.