• Title/Summary/Keyword: Complex Damage

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Efficient membrane element for cyclic response of RC panels

  • Tesser, Lepoldo;Talledo, Diego A.
    • Computers and Concrete
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    • v.20 no.3
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    • pp.351-360
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    • 2017
  • This paper presents an efficient membrane finite element for the cyclic inelastic response analysis of RC structures under complex plane stress states including shear. The model strikes a balance between accuracy and numerical efficiency to meet the challenge of shear wall simulations in earthquake engineering practice. The concrete material model at the integration points of the finite element is based on damage plasticity with two damage parameters. All reinforcing bars with the same orientation are represented by an embedded orthotropic steel layer based on uniaxial stress-strain relation, so that the dowel and bond-slip effect of the reinforcing steel are presently neglected in the interest of computational efficiency. The model is validated with significant experimental results of the cyclic response of RC panels with uniform stress states.

A Study on the Reliability and Reproducibility of 571 CMP process (STI CMP 공정의 신뢰성 및 재현성에 관한 연구)

  • 정소영;서용진;김상용;이우선;장의구
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2001.07a
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    • pp.25-28
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    • 2001
  • Recently, STI(Shallow Trench Isolation) process has attracted attention for high density of semiconductor device as a essential isolation technology. Without applying the conventional complex reverse moat process, CMP(Chemical Mechanical Polishing) has established the Process simplification. However, STI-CMP process have various defects such as nitride residue, torn oxide defect, damage of silicon active region, etc. To solve this problem, in this paper, we discussed to determine the control limit of process, which can entirely remove oxide on nitride from the moat area of high density as reducing the damage of moat area and minimizing dishing effect in the large field area. We, also, evaluated the reliability and reproducibility of STI-CMP process through the optimal process conditions.

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A Study on the Flexural Damage of RC Beams Under Fatigue Loading Using A Cyclic Creep Characteristics (반복크리프 특성을 이용한 피로하중을 받는 RC 보의 휨손상 연구)

  • 오병환;김동욱;홍경옥
    • Proceedings of the Korea Concrete Institute Conference
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    • 1998.04a
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    • pp.365-370
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    • 1998
  • The creep strain of the compression zone of concrete beams subjected to cyclic loading should be a significant factor in increasing strain and deflections. An analytical model which is similar to a previous one is presented to predict the increase in cyclic creep strain and the damage using the properties of the constituent materials: concrete and steel. The analytical expressions are compared with our experimental data. The effect of concrete-creep is accounted by the term En, Icr,n, and Mcr,n. In this study, it is proved that cyclic creep exponents 'n' in Cyclic Creep Model, according to the parameters -strength, range of stress- have the various values. It is hoped that with the availability of more experimental data and better understanding of some of the complex behavior, the model could be further improved.

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Influences of Prolonged Extracorporeal Circulation on Organ Function in Dogs (장시간의 체외순환이 생체에 미치는 영향)

  • 김의윤
    • Journal of Chest Surgery
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    • v.7 no.1
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    • pp.73-78
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    • 1974
  • Influences on organ function were studied in animals during prolonged extracorporeal circulation with a bubble type of oxygenator. More than six hours of total cardiopulmonary bypass was performed under mild hypothermia by means of an extracorporeal circulation system in five dogs. Obtained results were summarized as follows. 1. The renal function was not so impaired seriously until four hours of extracorporeal circulation. However, there was more serious impairment of renal function in this study when extracorporeal circulation was carried out for a period of five hours or more. 2. There was gradual hepatic damage during extracorporeal circulation and the damage was more significant after bypass for a period of five to six hours. 3. There was a significant decrease in serum K during bypass, irrespective of the pump oxygenator prime with a high K solution. The reason for this is complex and due to many factors, however, it was evidently related to serum glucose levels during extracorporal circulation.

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Blast Damage Assessment to a Modern Steel Structures

  • Mestreau Eric;Baum Joseph D.;Charman Chuck;Lee Seung;Sohn Young
    • 한국전산유체공학회:학술대회논문집
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    • 2006.05a
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    • pp.292-295
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    • 2006
  • The terrorist attack of September $11^{th}$ 2001 has enforced a new examination of the response of modern steel structures, such as those found in large warehouses, auditoriums and airport terminals, to terrorist bomb attack. The effort described in this paper assesses the potential damage to such a newly designed structure form a medium-size car bomb. The structure is mostly composed of a lightweight complex beam structure with large windows and skylights piercing through a corrugated roof. The structural response to the terrorist attack requires the modelling of various physics phenomena including bomb detonation, blast wave propagation, reflections, and refractions and resulting blast impact on the structure. Hence, a fluid/structure coupled methodology is used to perform the assessment.

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CHEMOPREVENTION OF SMOKE-RELATED DNA DAMAGE AND CANCER

  • Flora, Silvio-De;Roumen Balansky;Carlo Bennicelli;Anna Camoirano;Maria Bagnasco;Cristina Cartiglia;Elena Tampa;Mariagrazia Longobardi;Alberto Izzotti;Fransesco D Agostini
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2001.10a
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    • pp.50-51
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    • 2001
  • DNA damage is an essential step in the pathogenesis of cancer and probably of other chronic degenerative conditions related to cigarette smoke (CS), such as atherosclerosis, cardiomyopathies, etc. Although the major goal of primary prevention is to refrain from smoking, chemoprevention by means of dietary and pharmacological agents provides a complementary preventive strategy. In spite of its overwhelming epidemiological importance, experimental studies evaluating CS as a complex mixture are relatively scanty.(omitted)

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CHEMOPREVENTION OF SMOKE-RELATED DNA DAMAGE AND CANCER

  • Flora, Silvio-De;Roumen Balansky;Carlo Bennicelli;Anna Camoirano;Maria Bagnasco;Cristina Cartiglia;Elena Tampa;Elena Tampa;Mariagrazia Longobardi;Alberto Izzotti
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2001.10b
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    • pp.7-8
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    • 2001
  • DNA damage is an essential step in the pathogenesis of cancer and probably of other chronic degenerative conditions related to cigarette smoke (CS), such as atherosclerosis, cardiomyopathies, etc. Although the major goal of primary prevention is to refrain from smoking, chemoprevention by means of dietary and pharmacological agents provides a complementary preventive strategy. In spite of its overwhelming epidemiological importance, experimental studies evaluating CS as a complex mixture are relatively scanty.(omitted)

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DA-9601, a Phytomedicine Derived from Artemisia asiatica, Blocks the Increased Susceptibility of Portal Hypertensive Gastropathy to Ethanol Damage

  • Oh, Tae-Young;Ahn, Byoung-Ok;Ryu, Byung-Kweon;Kim, Soon-Hoe;Kim, Won-Bae;Lee, Eun-Bang
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1998.11a
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    • pp.124-124
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    • 1998
  • Portal hypertensive gastropathy (PHG) is part of a complex syndrome which occurs as a complication of chronic liver disease and portal hypertension. The gastric mucosa in these patients shows typical congestion of ‘mosaic-like’ pattern and vulnerable to various noxious agents such as NSAIDs and ethanol. We previously reported that DA-9601, a quality-controlled extract from Artemisia asiatica, exhibits cytoprotection against various gastritis models. In the present study we investigated the effect of DA-9601 on ethanol-induced gastric damage in PHG rats. Experimental PHG was produced by CBD ligation in SD rats. DA-9601 was orally administered at a dose of 30 mg/kg or 100 mg/kg daily for 2 weeks.

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Seismic Design and Isolation Design for Highway Bridges (교량구조물의 내진설계 및 면진설계(교량 받침을 중심으로))

  • 전규식
    • Proceedings of the Earthquake Engineering Society of Korea Conference
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    • 1998.04a
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    • pp.115-122
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    • 1998
  • Earthquake damage civil engineering structures every year in the world and bridges are no exception. Bridge structures have proven to be vulnerable to earthquake, sustaining damage to substructure and foundation and being totally destroys as superstructures collapse from their supporting elements. The poor seismic performance of bridge structures is surprising in view of the substantial advance made in design and construction for vertical load. Recently, bridge spans have been pushed further than before, alignment has become increasingly complex and aesthetic requirement have been become more demanding. To reduce the seismic force and to improve the safety of the advanced bridges, the bridge bearings which are the substructures and foundations and their connections to the superstructure become more important and critical elements. Therefore, the functions about seismic devices to be using as bridge bearing are discussed.

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DNA Repair of Eukaryotes Associated with Non-coding Small RNAs

  • Kang, Han-Chul;Yoon, Sang-Hong;Lee, Chang-Muk;Roh, Kyung Hee
    • Journal of Applied Biological Chemistry
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    • v.56 no.1
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    • pp.37-42
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    • 2013
  • In eukaryotes, most of the genome are transcribed, however only a small proportion of total transcripts encodes for protein, thus resulting in many of noncoding RNAs. In order to recover DNA damage including DNA double-strand breaks (DSBs) eukaryotes have evolved complex mechanisms and these are processed through coordinated mechanisms of protein sensors, transducers, and effectors including RNAs. During recent years, small RNAs have been increasingly studied and gradually considered as key regulators in various aspects of biology. Upon DNA damage, small RNAs including diRNAs (DSB induced RNA) are generated in both plant and human cell lines. Inhibition of their biogenesis has severe influence on DSB repair system.