• 제목/요약/키워드: Complete response

검색결과 1,062건 처리시간 0.031초

IMPACT OF UV RADIATION SENSITIVITY ON DERMATOPHYTES (Microsporum boullardii)

  • Shrivastava, J.N.;Satsangi, G.P.;Jain, Shradha
    • Journal of Photoscience
    • /
    • 제9권2호
    • /
    • pp.466-469
    • /
    • 2002
  • An experiment has been conducted to measure the impact of UV radiation sensitivity on dermatophytes (Microsporum boullardii) by different UV radiation exposure time interval (1 min, 2 min 5 min, 10 min and 20 min) in degradation of keratin (Feather) in growth promoting substances of protein, cysteine, cystine and methionine from 7 to 28 days of incubation period. Mutant strain caused maximum weight loss with 1 minutes of UV radiation exposure at 21 day and mutant strain became immune in sensitivity at 14 days for decomposition of feathers. Maximum protein caused at 21st days with 20 minutes U.V radiation exposure and immune sensitivity had deducted with other UV radiation exposure time. On 28 days, mutant strains became immune with all exposure times, Whereas maximum methionine caused at 21st days with 20 minutes UV radiation exposure. Maximum cysteine caused at $14^{th}$ day with 5 minutes UV radiation exposure and mutant strain showed immune response at all time periods. Cystine production was also followed by cysteine at 21 day and also showed complete immune response with 1 and 2 minutes UV radiation exposure at7 and 14 days. Thus mutant strain of Microspornm boullardii can be used as a biotechnological tool for production of growth promoting substances.

  • PDF

Interaction of Nitric Oxide and Renin Angiotensin System in Pulmonary Arterial Circulation of RHR

  • Lee, Byung-Ho;Shin, Hwa-Sup
    • Archives of Pharmacal Research
    • /
    • 제20권5호
    • /
    • pp.389-395
    • /
    • 1997
  • We investigated the interaction between nitric oxide and the renin angiotensin system in regulating isolated pulmonary arterial tension and pulmonary arterial pressure (PAP) in renal hypertensive rats (RHR) made by complete ligation of left renal artery. Losartan induced a depressor response that was smaller in RHR than in normotensive rats (NR) (3.3 and 7.0 mmHg, respectively, at 3.0 mg/kg, p<0.05), and the response was significantly reduced by $N^{G}$-nitro-Larginine methyl ester (L-NAME). Angiotensin II elevated the PAP (7.6 and 10.8 mmHg at $0.1 {\mu}g/kg$; 20.3 and 23.6 mmHg at $1.0{\mu}g/kg$, respectively) and contracted the isolated pulmonary artery ($pD_2$: 8.79 and 8.71, respectively) from both NR and RHR with similar magnitude, and these effects were significantly enhanced by L-NAME in NR, but not in RHR. Acetylcholine lowered the PAP slightly less effectively in RHR than in NR (3.8 and 6.0 mmHg at 10 .mu.g/kg, respectively) and relaxed the pulmonary artery precontracted with norepinephrine in both rats with similar magnitude ($E_max$: 60.8 and 63.6%, respectively), and the effect being completely abolished after pretreatment.with L-NAME or removal of endothelial cells. These results suggest that nitric oxide interacts with renin angiotensin system to control the pulmonary vascular tension and pulmonary arterial circulation of RHR.R.

  • PDF

Toward Functional Genomics of Plant-Pathogen Interactions: Isolation and Analysis of Defense-related Genes of Rot Pepper Expressed During Resistance Against Pathogen

  • Park, Do-Il;Lee, Sang-Hyeob
    • The Plant Pathology Journal
    • /
    • 제18권2호
    • /
    • pp.63-67
    • /
    • 2002
  • To understand plant-pathogen interactions, a complete set of hot pepper genes differentially expressed against pathogen attack was isolated. As an initial step, hundreds of differentially expressed cDNAS were isolated from hot pepper leaves showing non-host resistance against bacterial plant pathogens (Xanthomonas campestris pv. glycines and Pseudomonas syringae pv. syringae) using differential display reverse transcription polymerase chain reaction (DDDRT-PCR) technique. Reverse Northern and Northern blot analyses revealed that 50% of those genes were differentially expressed in pepper loaves during non-host resistance response. Among them, independent genes without redundancy were micro-arrayed for further analysis. Random EST sequence database were also generated from various CDNA libraries including pepper tissue specific libraries and leaves showing non-host hypersensitive response against X. campestris pv. glycines. As a primary stage, thousands of cDNA clones were sequenced and EST data were analyzed. These clones are being spotted on glass slide to study the expression profiling. Results of this study may further broaden knowledge on plant-pathogen interactions.

호텔개발사업의 불확실성에 전략적으로 대응하기 위한 실물옵션 적용 연구 (A Study on Application of Real Option for Strategic Response to Uncertainty in Hotel Development Project)

  • 권태인;이상효;김재준
    • 한국디지털건축인테리어학회논문집
    • /
    • 제10권2호
    • /
    • pp.5-12
    • /
    • 2010
  • Unlike housing development project that can ensure profit by selling built units, a hotel development depends on long-term business operation to be profitable due to characteristics of service industry. The expected cash flow has substantial uncertainty depending on room occupancy rate and room charge. Thus, even after construction is complete, business risk tends to rise. It is necessary to ensure strategic response to uncertainty in future value of a hotel. The objective of the study is to explore strategic measures to deal with risk and uncertain future value in hotel development project by adopting abandonment option, which is a type of real options. The case in analysis had sevenyears of project period: Two years for construction, and five years for operation; a plan was made to sell the hotel after five years' of operation. For the research purpose, option value ofrecoverable investment amount was estimated, and value of abandonment option was KRW 124.921 billion. When abandonment option is applied, the project value was deemed to be KRW 120.592 billion. Generally, the amount of loss is enormous when a real estate project like a hotel development fails, and therefore, application of option is expected to be an effective measure to leverage uncertainty of a project.

Performance Test of Asynchronous Process of OGC WPS 2.0: A Case Study for Geo-based Image Processing

  • Yoon, Gooseon;Lee, Kiwon
    • 대한원격탐사학회지
    • /
    • 제33권4호
    • /
    • pp.391-400
    • /
    • 2017
  • Geo-based application services linked with the Open Geospatial Consortium (OGC) Web Processing Service (WPS) protocol have been regarded as an important standardized framework for of digital earth building in the web environments. The WPS protocol provides interface standards for analysis functionalities within geo-spatial processing in web-based service systems. Despite its significance, there is few performance tests of WPS applications. The main motivation in this study is to perform the comparative performance test on WPS standards. Test system, which was composed of WPS servers, WPS framework, data management module, geo-based data processing module and client-sided system, was implemented by fully open source stack. In this system, two kinds of geo-based image processing functions such as cloud detection and gradient magnitude computation were applied. The performance test of different server environments of non-WPS, synchronous WPS 1.0 and asynchronous WPS 2.0 was carried out using 100 threads and 400 threads corresponds client users on a web-based application service. As the result, at 100 threads, performance of three environments was within an adjacent range in the average response time to complete the processing of each thread. At 400 threads, the application case of WPS 2.0 showed the distinguished characteristics for higher performance in the response time than the small threads cases. It is thought that WPS 2.0 contributes to settlement of without performance problems such as time delay or thread accumulation.

Electromagnetic Model to Estimate the Vibrations of a Switched Reluctance Machine on the Basis of the Eelctric Power Supply

  • Badreddine, Benabdallah Mohammed
    • Journal of Electrical Engineering and Technology
    • /
    • 제3권1호
    • /
    • pp.60-67
    • /
    • 2008
  • The vibrations and noise origin in electric material is due to several coupled physical phenomena. The revolving electric machine complete modeling is complex; it does not allow simple parametric machine structure studies for various operation modes. This work presents a simple electromagnetic model which makes possible the machine principal parts flow estimation from flux density. Special interest is given in determining Switched Reluctance Machine (S.R.M) radial acceleration in accordance with the current supply. Our focus will be only on the magnetic origin efforts that are dominating in the S.R.M. The efforts calculation versus the current is presented in the case of a machine with a linearized rate. These efforts are considered as a tangential force producing the torque and a radial force that generates no torque. The application is realized on a 6/4 low power S.R.M type (6 stator teeth and 4 teeth rotor). The mechanical response is substituted in a transfer function. The model takes account of the power supply of the machine, the relation between the current supply and the efforts as well as the vibratory response of the machine to these efforts. Finally, the model is validated by comparison with similar experimental results within the framework of the definite assumptions.

Bounds on plastic strains for elastic plastic structures in plastic shakedown conditions

  • Giambanco, Francesco;Palizzolo, Luigi;Caffarelli, Alessandra
    • Structural Engineering and Mechanics
    • /
    • 제25권1호
    • /
    • pp.107-126
    • /
    • 2007
  • The problem related to the computation of bounds on plastic deformations for structures in plastic shakedown condition (alternating plasticity) is studied. In particular, reference is made to structures discretized by finite elements constituted by elastic perfectly plastic material and subjected to a special combination of fixed and cyclic loads. The load history is known during the steady-state phase, but it is unknown during the previous transient phase; so, as a consequence, it is not possible to know the complete elastic plastic structural response. The interest is therefore focused on the computation of bounds on suitable measures of the plastic strain which characterizes just the first transient phase of the structural response, whatever the real load history is applied. A suitable structural model is introduced, useful to describe the elastic plastic behaviour of the structure in the relevant shakedown conditions. A special bounding theorem based on a perturbation method is proposed and proved. Such theorem allows us to compute bounds on any chosen measure of the relevant plastic deformation occurring at the end of the transient phase for the structure in plastic shakedown; it represents a generalization of analogous bounding theorems related to the elastic shakedown. Some numerical applications devoted to a plane steel structure are effected and discussed.

Comparative study on response of thiocyanate shock load on continuous and fed batch anaerobic-anoxic-aerobic sequential moving bed reactors

  • Sahariah, B.P.;Chakraborty, S.
    • Environmental Engineering Research
    • /
    • 제20권1호
    • /
    • pp.65-72
    • /
    • 2015
  • A comparative study on response of a toxic compound thiocyanate ($SCN^-$) was carried out in continuous and fed batch moving bed reactor systems. Both systems had three sequential anaerobic, anoxic and aerobic reactors and operated at same hydraulic retention time. Feed $SCN^-$ was first increased from 600 mg/L to 1,000 mg/L for 3 days (shock 1) and then from 600 to 1,200 mg/L for 3 days (shock 2). In anaerobic continuous reactor, increase of effluent COD (chemical oxygen demand) due to shock load was only 2%, whereas in fed batch reactor it was 14%. In anoxic fed batch reactor recovery was partial in terms of $SCN^-$, phenol, COD and $NO{_3}{^-}$-N and $NO{_2}{^-}$-N removals and in continuous reactor complete recovery was possible. In both systems, inhibition was more significant on aerobic reactors than anaerobic and anoxic reactors. In aerobic reactors ammonia removal efficiency deteriorated and damage was irreversible. Present study showed that fed batch reactors showed higher substrate removal efficiency than continuous reactors during regular operation, but are more susceptible to toxic feed shock load and in nitrifying reactor damage was irreversible.

Natural frequency characteristics of composite plates with random properties

  • Salim, S.;Iyengar, N.G.R.;Yadav, D.
    • Structural Engineering and Mechanics
    • /
    • 제6권6호
    • /
    • pp.659-671
    • /
    • 1998
  • Exercise of complete control on all aspects of any manufacturing / fabrication process is very difficult, leading to uncertainties in the material properties and geometric dimensions of structural components. This is especially true for laminated composites because of the large number of parameters associated with its fabrication. When the basic parameters like elastic modulus, density and Poisson's ratio are random, the derived response characteristics such as deflections, natural frequencies, buckling loads, stresses and strains are also random, being functions of the basic random system parameters. In this study the basic elastic properties of a composite lamina are assumed to be independent random variables. Perturbation formulation is used to model the random parameters assuming the dispersions small compared to the mean values. The system equations are analyzed to obtain the mean and the variance of the plate natural frequencies. Several application problems of free vibration analysis of composite plates, employing the proposed method are discussed. The analysis indicates that, at times it may be important to include the effect of randomness in material properties of composite laminates.

Radioactive Seed Implantation and Lobaplatin Chemotherapy Are Safe and Effective in Treating Patients with Advanced Lung Cancer

  • Li, Jia-Rui;Sun, Yu;Liu, Lin
    • Asian Pacific Journal of Cancer Prevention
    • /
    • 제16권9호
    • /
    • pp.4003-4006
    • /
    • 2015
  • Objecive: To investigate the clinical safety and efficacy of CT-guided $^{125}iodine$ (125I) seed implantation combined with percutaneous intra-tumor injection of chemotherapy emulsion of lobaplatin and lipiodol in treating patients with advanced lung cancer. Materials and Methods: Patients with advanced lung cancer and treated with spiral CT-guided $^{125}I$ seed implantation combined with percutaneous intra-tumor injection of chemotherapy emulsion of lobaplatin and lipiodol were recruited. Results: Of the 36 patients, there were 40 nidi in total. The contrast-enhanced CT evaluation was conducted 60 d after treatment. Response evaluation suggested that 4 patients achieved complete remission (CR), 24 partial remission (PR), 4 stable disease (SD) and 4 progression disease (PD), with a total response rate of 77.8% (28/36). Conclusions: CT-guided $^{125}I$ seed implantation combined with percutaneous intra-tumor injection of chemotherapy emulsion of lobaplatin and lipiodol are safe and effective in treating patients with advanced lung cancer.