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http://dx.doi.org/10.7314/APJCP.2015.16.9.4003

Radioactive Seed Implantation and Lobaplatin Chemotherapy Are Safe and Effective in Treating Patients with Advanced Lung Cancer  

Li, Jia-Rui (Invasive Technology Department, The First Hospital of Jilin University)
Sun, Yu (Invasive Technology Department, The Third Hospital of Jilin University)
Liu, Lin (Invasive Technology Department, The Third Hospital of Jilin University)
Publication Information
Asian Pacific Journal of Cancer Prevention / v.16, no.9, 2015 , pp. 4003-4006 More about this Journal
Abstract
Objecive: To investigate the clinical safety and efficacy of CT-guided $^{125}iodine$ (125I) seed implantation combined with percutaneous intra-tumor injection of chemotherapy emulsion of lobaplatin and lipiodol in treating patients with advanced lung cancer. Materials and Methods: Patients with advanced lung cancer and treated with spiral CT-guided $^{125}I$ seed implantation combined with percutaneous intra-tumor injection of chemotherapy emulsion of lobaplatin and lipiodol were recruited. Results: Of the 36 patients, there were 40 nidi in total. The contrast-enhanced CT evaluation was conducted 60 d after treatment. Response evaluation suggested that 4 patients achieved complete remission (CR), 24 partial remission (PR), 4 stable disease (SD) and 4 progression disease (PD), with a total response rate of 77.8% (28/36). Conclusions: CT-guided $^{125}I$ seed implantation combined with percutaneous intra-tumor injection of chemotherapy emulsion of lobaplatin and lipiodol are safe and effective in treating patients with advanced lung cancer.
Keywords
Advanced lung cancer; radioactive seed; chemotherapy emulsion of lobaplatin and lipiodol;
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Times Cited By KSCI : 7  (Citation Analysis)
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