• Title/Summary/Keyword: Complementarity Structure

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Plant RNA Virus-Host Interaction: Potato virus X as a model system

  • Kim, Kook-Hyung
    • Proceedings of the Korean Society of Plant Pathology Conference
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    • 2003.10a
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    • pp.14-14
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    • 2003
  • Potato virus X (PVX), the type member of Potexvirus genus, is a flexuous rod-shaped virus containing a single-stranded (+) RNA. Infection by PVX produces genomic plus- and minus-strand RNAs and two major subgenomic RNAs (sgRNAs). To understand the mechanism for PVX replication, we are studying the cis- and/or trans-acting elements required for RNA replication. Previous studies have shown that the conserved sequences located upstream of two major sgRNAs, as well as elements in the 5' non-translated region (NTR) affect accumulation of genomic and sg RNAs. Complementarity between sequences at the 5' NTR and those located upstream of two major sgRNAs and the binding of host protein(s) to the 5' NTR have shown to be important for PVX RNA replication. The 5 NTR of PVX contains single-stranded AC-rich sequence and stem-loop structure. The potential role(s) of these cis-elements on virus replication, assembly, and their interaction with viral and host protein(s) during virus infection will be discussed based on the data obtained by in vitro binding, in vitro assembly, gel shift mobility assay, host gene expression profiling using various mutants at these regions.

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A PID Controller Design for an Attracton Type Magnetic Levitation System Considering $H_{\infty}$ Performance ($H_{\infty}$ 성능을 고려한 흡인식 자기부상 시스템의 PID 제어기 설계)

  • Kim, Seog-Joo;Kim, Chun-Kyung;Kim, Jong-Moon;Park, Min-Kook
    • Proceedings of the KIEE Conference
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    • 2001.07d
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    • pp.2120-2122
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    • 2001
  • This paper describes a PID controller for an attraction type magnetic levitation system considering $H^{\infty}$ performance. PID controllers are a kind of fixed structure reduced order controllers. Using change of variables a reduced order control problem can be recast into a static output feedback control problem and can be solved efficiently by LMI(Linear Matrix Inequality) method. In this paper, cone complementarity method is adopted and the simulation shows good results.

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Comparison of Breeding System Between Single Population and Two Sub-population Scheme by Computer Simulation II. Different genetic level for Sub-populations

  • Oikawa, T.;Matsura, Y.;Sato, K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.10 no.4
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    • pp.428-434
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    • 1997
  • The effect of genetic diversity in sub-populations on breeding efficiency was examined with prospect of potential crossbreeding. Simulation study of selection was performed for 20 generations with 20 replications each, comparing average breeding values and inbreeding coefficients between the two breeding systemes; single population scheme and two population scheme. The different genetic levels were assumed to be caused by different gene frequencies. Phenotypes of two traits generated polygenic effect with additive 36 loci and residuals distributed normally were selected by selection index procedure. High genetic gain with less inbreeding was clearly recognized in the single population scheme, independently of difference in genetic level, economic weight and genetic correlation. Genetic correlation after selection in the single population scheme was lower than the two population scheme. When crossbreeding between the sub-population was taken into account, superiority of the two population scheme was suggested under those restrictions; difference in genetic level is moderate, selection criterion for the two traits is not far from even economic weight, and genetic correlation is positive with low to moderate value. The use of complementarity increased the possibility of the two population scheme.

Recent Advances in Structural Studies of Antifreeze Proteins (구조 생물학을 이용한 Antifreeze protein의 최근 연구동향)

  • Lee, Jun-Hyuck;Lee, Sung-Gu;Kim, Hak-Jun
    • Ocean and Polar Research
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    • v.33 no.2
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    • pp.159-169
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    • 2011
  • Antifreeze proteins (AFPs) have ice binding affinity, depress freezing temperature and inhibit ice recystallization which protect cellular membranes in polar organisms. Recent structural studies of antifreeze proteins have significantly expanded our understanding of the structure-function relationship and ice crystal growth inhibition. Although AFPs (Type I-IV AFP from fish, insect AFP and Plant AFP) have completely different fold and no sequence homology, they share a common feature of their surface area for ice binding property. The conserved ice-binding sites are relatively flat and hydrophobic. For example, Type I AFP has an amphipathic, single ${\alpha}$-helix and has regularly spaced Thr-Ala residues which make direct interaction with oxygen atoms of ice crystals. Unlike Type I AFP, Type II and III AFP are compact globular proteins that contain a flat ice-binding patch on the surface. Type II and Type III AFP show a remarkable structural similarity with the sugar binding lectin protein and C-terminal domain of sialic acid synthase, respectively. Type IV is assumed to form a four-helix bundle which has sequence similarity with apolipoprotein. The results of our modeling suggest an ice-binding induced structural change of Type IV AFP. Insect AFP has ${\beta}$-helical structure with a regular array of Thr-X-Thr motif. Threonine residues of each Thr-X-Thr motif fit well into the ice crystal lattice and provide a good surface-surface complementarity. This review focuses on the structural characteristics and details of the ice-binding mechanism of antifreeze proteins.

An Analysis of LCL Export Freight by Transportation Mode in Busan Area (부산지역 수송수단별 LCL 수출화물 특성 분석)

  • Cho, Yeong-Kyu;Lee, Gyeong-Gu;Kwak, Kyu-Seok;Nam, Ki-Chan
    • Journal of Navigation and Port Research
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    • v.33 no.6
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    • pp.409-414
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    • 2009
  • As Korea has the economic structure heavily depending on exporting commodities, the importance of both maritime and air transportation mode is significant. Accordingly, for the sustainable and stable export the freight transportation market by mode needs to be developed complementarity each other. This paper, therefore, aims at analysing the LCL commodities transported by the two mode in terms of unit price, freight charge bearability and price structure. For this around 500 bill of lading(B/L) are collected and analysed resulting in deriving the distinctive characteristics of commodities by mode and the implication for price policy.

Korea-China FTA and Trade Competitiveness of Agricultural.Fisheries Industry to China in Jeonnam Province: Comparative Advantage and Intra-Industry Trade (한.중 FTA와 전남의 대중국 농수산업 무역경쟁력: 비교우위와 산업내무역)

  • Kim, Chang-Beom
    • International Commerce and Information Review
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    • v.15 no.3
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    • pp.333-352
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    • 2013
  • Various trade competitiveness-related indices such as TSI, CACI, MCAI, and IITI are applied to examine the trade structure of comparative advantage and complementarity between Jonnama and Chinese on agricultural and Fisheries industry using the data of years 2000-2012 of KITA. The result show that Joennam has specialized in the product of other products of animal origin and preparations of vegetables, fruit, nuts, other par. The Intra-Industry trade level of Korean agricultural and Fisheries industry were in the trend of uprising with vertical intra-industry pattern dominant among them in the product live trees other live plants, edible vegetables roots, oil seeds oleaginous fruit, other vegetable saps extracts, preparations of cereals flour starch. As expected, Jeonnam region show that the high quality vertical IIT, indicating that Jeonnam export high-priced high quality products to China and import cheap low quality items from China. Finally, the innovation of production system, distribution modernization, value-maximizing strategies were suggested as a strengthening method of competitiveness.

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A Method of Coupling Expected Patch Log Likelihood and Guided Filtering for Image De-noising

  • Wang, Shunfeng;Xie, Jiacen;Zheng, Yuhui;Wang, Jin;Jiang, Tao
    • Journal of Information Processing Systems
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    • v.14 no.2
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    • pp.552-562
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    • 2018
  • With the advent of the information society, image restoration technology has aroused considerable interest. Guided image filtering is more effective in suppressing noise in homogeneous regions, but its edge-preserving property is poor. As such, the critical part of guided filtering lies in the selection of the guided image. The result of the Expected Patch Log Likelihood (EPLL) method maintains a good structure, but it is easy to produce the ladder effect in homogeneous areas. According to the complementarity of EPLL with guided filtering, we propose a method of coupling EPLL and guided filtering for image de-noising. The EPLL model is adopted to construct the guided image for the guided filtering, which can provide better structural information for the guided filtering. Meanwhile, with the secondary smoothing of guided image filtering in image homogenization areas, we can improve the noise suppression effect in those areas while reducing the ladder effect brought about by the EPLL. The experimental results show that it not only retains the excellent performance of EPLL, but also produces better visual effects and a higher peak signal-to-noise ratio by adopting the proposed method.

A Double Helix DNA Structure Based on Block Circulant Matrix (II) (블록순환 행렬에 의한 이중나선 DNA 구조 (II))

  • Park, Ju-Yong;Kim, Jeong-Su;Lee, Moon-Ho
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.16 no.5
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    • pp.229-233
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    • 2016
  • In this paper, we present the four genetic nitrogenous bases of C, U(T), A, G to matrices and describe the structures from $4{\times}4$ RNA(ribose nucleic acid) to $8{\times}8$ DNA((deoxyribose nucleic acid) matrices. we analysis a deoxyribose nucleic acid (DNA) double helix based on the block circulant Hadamard-Jacket matrix (BCHJM). The orthogonal BCHJM is anti-symmetric pair complementary of the core DNA. The block circulant ribonucleic acid (RNA) repair damage reliability is better than the conventional double helix. In case of k=4 and N=1, the reliability of block circulant complementarity is 93.75%, and in case of k=4 and N=4, it is 98.44%. Therefore it improves 4.69% than conventional case of double helix.

A negative stiffness inerter system (NSIS) for earthquake protection purposes

  • Zhao, Zhipeng;Chen, Qingjun;Zhang, Ruifu;Jiang, Yiyao;Pan, Chao
    • Smart Structures and Systems
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    • v.26 no.4
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    • pp.481-493
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    • 2020
  • The negative stiffness spring and inerter are both characterized by the negative stiffness effect in the force-displacement relationship, potentially yielding an amplifying mechanism for dashpot deformation by being incorporated with a series tuning spring. However, resisting forces of the two mechanical elements are dominant in different frequency domains, thus leading to necessary complementarity in terms of vibration control and the amplifying benefit. Inspired by this, this study proposes a Negative Stiffness Inerter System (NSIS) as an earthquake protection system and developed analytical design formulae by fully utilizing its advantageous features. The NSIS is composed of a sub-configuration of a negative stiffness spring and an inerter in parallel, connected to a tuning spring in series. First, closed-form displacement responses are derived for the NSIS structure, and a stability analysis is conducted to limit the feasible domains of NSIS parameters. Then, the dual advantageous features of displacement reduction and the dashpot deformation amplification effect are revealed and clarified in a parametric analysis, stimulating the establishment of a displacement-based optimal design framework, correspondingly yielding the design formulae in analytical form. Finally, a series of examples are illustrated to validate the derived formulae. In this study, it is confirmed that the synergistic incorporation of the negative stiffness spring and the inerter has significant energy dissipation efficiency in a wide frequency band and an enhanced control effect in terms of the displacement and shear force responses. The developed displacement-based design strategy is suitable to utilize the dual benefits of the NSIS, which can be accurately implemented by the analytical design formulae to satisfy the target vibration control with increased energy dissipation efficiency.

Bridging the Gap Between Science and Industry: The Fraunhofer Model

  • Klingner, Raoul;Behlau, Lothar
    • STI Policy Review
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    • v.3 no.2
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    • pp.130-151
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    • 2012
  • Fraunhofer was founded in 1949 and grew into Europe's largest application-oriented research organization. Fraunhofer currently employs over 20,000 members in Germany, is internationally networked, and manages an R&D budget of over 1,8 Billion Euros per year. An important step for Fraunhofer to become an integral component of the German innovation system was the introduction of the Fraunhofer Model of financing based on a performance-related system of financial management. The underlying model of the allocation and distribution of public funding to Fraunhofer that is subsequently allotted to specific research groups is one of the success factors of Fraunhofer. Fraunhofer is proud of its decentralized organizational model. Fraunhofer is comprised of 60 Institutes in Germany working in different fields, under one legal framework, and with a strong brand value. Every Fraunhofer Institute is affiliated with a German University and every institute director simultaneously holds a chair at the affiliated university. It is a challenge for the headquarter organization to balance the intended competition of individual Fraunhofer Institutes with complementarity cooperation in science among Fraunhofer-Institutes, especially when coming from different knowledge domains; however, this goal results in a significant advantage. The unique strengths of Fraunhofer offer system solutions in a world with increasingly complex R&D challenges. While growing to become the largest organization on Europe to focus on applied research it is the challenge to remain an agile organization that is flexible in organizational structure. Fraunhofer has reached a well-recognized position in the European innovation landscape. It is often referred to by science and governments as a role model for innovation policy and a key element of the latest successes in the German economy that has recovered quicker from the latest economic crisis than most other western economies. The paper explains Fraunhofer as an organizational paradigm and its underlying management model to elaborate on the challenges of managing a research organization. We wish to show how it is possible to transfer the management model and philosophy of Fraunhofer to innovation systems with different framework conditions and challenges. A universal conclusion may be drawn based on the description of Fraunhofer; however, changes in existing structures and innovation systems cannot be implemented over night.