• Asian Pacific Journal of Cancer Prevention
• /
• v.17 no.5
• /
• pp.2597-2603
• /
• 2016

Ovarian cancer is a highly malignant neoplasm with high mortality rates. Research to identify markers facilitating early detection has been pursued for many years. Currently, diagnosis is based on the CA 125 and HE4 markers, as well as the ROMA algorithm. The search continues for new proteins that meet the criteria of good markers A total of 90 patients were included in the present study, allocated into: group 1, ovarian cancer, with 29 patients; group 2, endometrial cysts, with 30s; and group 3, simple ovarian cysts, with 31. Following histopathological verification, the CA 125, HE4, and metalloproteinase 3 (MMP3) levels were determined and the ROMA algorithm was calculated for all patients. The mean concentrations of all determined proteins, CA 125, HE4, and MMP3, as well as the ROMA values, were significantly higher in group 1 (ovarian cancer) compared to group 3 (simple ovarian cysts). The highest significant differences for the CA 125 levels (p<0.000001) and ROMA (p<0.000001) values were observed in postmenopausal women. For HE4, statistical significance was at the level of p=0.00001 compared to p=0.002 for MMP3. For the differentiation between ovarian cancer and endometrial cysts, the respective AUC ratios were obtained for CA 125, HE4, and MMP3 levels, as well as the ROMA values ( 0,93 / 0,96 / 0,75 / 0,98). After removing the post-menopausal patients, the MMP3 AUC value for ovarian cancer vs. benign ovarian cysts increased to 0.814. For post-menopausal women, the MMP3 AUC value for ovarian cancer vs. endometrial cysts was 0.843. As suggested by the results above, both the CA 125 and HE4 markers, as well as the ROMA algorithm, meet the criteria of a good diagnostic test for ovarian cancer. MMP3 seems to meet the criteria of a good diagnostic test, particularly in postmenopausal women; however, it is not superior to the tests used to date.

• Journal of Food Hygiene and Safety
• /
• v.33 no.1
• /
• pp.65-70
• /
• 2018

Monitoring of Listeria monocytogenes, the causative agent of listeriosis, in food is inportant for public health. The Korean Food Standards Codex has adopted a 'zero-tolerance' policy for L. monocytogenes. The standard detection method of L. monocytogenes is based on enrichment. Thus, proper enrichment methods need to be instituted to ensure quality control of the detection procedures. In this study, the growth of L. monocytogenes and Listeria innocua as a mixed culture in Listeria enrichment broth (LEB) was monitored during artificial contamination of enrichment culture. We confirmed competitive growth or interspecies inhibitory activity of L. monocytogenes and L. innocua. Interspecies growth differences and the inhibitory activity of different inoculation and mixtures L. innocua against L. monocytogenes were examined. The concentration of L. monocytogenes must be 2.0 log CFU/mL or more than L. innocua to grow better than L. innocua. It is known that Listeria spp. and L. monocytogenes show growth difference during LEB, resulting in the risk of false-negative results. The inhibition of L. monocytogenes by L. innocua was always observed when present at lower concentrations. However, it was confirmed that L. innocua suppressed when L. monocytogenes was present at a higher concentration. Therefore if a mixture of Listeria spp. is present, detecting L. monocytogenes is difficult. Thus, a new enrichment broth to improve the detection rate of L. monocytogenes is needed.

• Journal of Environmental Health Sciences
• /
• v.44 no.4
• /
• pp.340-347
• /
• 2018

Objectives: This study was performed to determine environmental hazard factors and provide more eco-friendly child activity spaces within children's playgrounds installed in Gyeonggi-do Province. Methods: Basic (XRF) and precise (ICP, UV) inspections were conducted. The test items examined were heavy metals and parasite eggs. As a sampling point, painted finish materials (180), synthetic rubber (50), and sand (50) were selected. Results: The total excess rate of heavy metals in the XRF was found to be 7.4% (17/230 points). In a comparison between the basic and precise inspections with 17 excess points, the concentration deviation between the two tests was found to be from 0.01 to 7.7 times, resulting in a large difference. Furthermore, all the excess samples were dual samples. However, the contribution rates of Pb and $Cr^{6+}$ to combined concentration were found to be 85.1 and 14.9% for basic inspection and 91.9 and 8.1% for precise inspections, so there is a similar tendency between the two tests. The excess rate of parasite eggs in sand was expressed at 6%. The excess rate of heavy metals in synthetic rubber was found to be 0%. Conclusion: The reliability of the XRF is low. However, considering the contribution rate of Pb and $Cr^{6+}$ between the two tests, it is likely to be applicable for screening. Dual samples provided high concentrations and excess samples and care should be taken when managing them.

• KDI Journal of Economic Policy
• /
• v.31 no.2
• /
• pp.195-234
• /
• 2009

This paper examines relative contributions of extensive margin and intensive margin of Korean exports growth to China after 1990s', based on an analytical approach proposed by the Hummels and Klenow(2005). In this paper, extensive margin is defined as a weighted count of Korean exports categories relative to the rest of world's export categories to China. On the other hand, intensive margin refers to Korean exports to China relative to the rest of the world's exports to China, exclusively in those product categories that Korea exports to China. According to the results of the analysis, the expansion of Korean exports to China was induced mainly by the increase of intensive margin. This result is consistent with $Besede{\check{s}}$ and Prusa(2007) as well as the Helpman, Melitz and Rubinstein(2007) who suggest that intensive margin is a more important factor than extensive margin for sustaining growth of export in the long term. In addition, this paper shows that the survival rates of exports of parts and components and capital goods is relatively higher in comparison to those of primary and consumption goods. This implies that the expansion of international division of labor under the global production network could substantially affect the survival of exports.

• Journal of the HCI Society of Korea
• /
• v.1 no.2
• /
• pp.19-26
• /
• 2006

This paper presents a novel pneumatic tactile display that can deliver some useful information. The air-jet display forms 5 by 5 arrays and features air nozzles with an external diameter of 2.4mm and internal diameter of 1.5 mm. In comparison with other tactile displays such as vibrotactile, there is little concrete psychophysical data relating to pneumatic displays, a fact which hinders their adoption. This paper addresses this challenge, and presents brief psychophysical studies examining localization rate, the two point threshold, stimulus intensity and the temporal threshold of cues produced by pneumatic air jets. Two groups of subjects were used in these studies, subsequently termed groups A and B. Both were comprised of eight participants. In the case of localization study we obtained 58.13% and 85.9% of localization rates each for dense display and sparse display. Two-points threshold test showed the length of gap between two air-jet stimuli which subjects can detect. However, it was formidable to find out precise temporal resolution of PTI owing to the limitation of capability of the pneumatic valves. Lastly, the results of stimulus intensity study suggest that by varying the size of a pneumatically created tactile stimulus, we can effectively vary its perceived magnitude.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
• /
• v.4 no.3
• /
• pp.237-245
• /
• 1999

Rates of photosynthesis and respiration of Laminaria japonica sporophytes cultivated on the southeastern coast of Korea were monthly measured in situ and under constant temperature and nitrogen concentration in laboratory from February to July 1996 in order to understand the seasonal photosynthetic performance of this alga. P-I (the relationship between photosynthsis and irradiance) parameters measured in situ varied seasonally. Photosynthetic capacity ($P_{max}$) reached its maximum in March (6.64 mg $O_2{\cdot}gdw^{-1}{\cdot}h^{-1}$) and gradually decreased thereafter. Photosynthetic efficiency (${\alpha}$), which ranged from 0.026 to 0.106, generally showed a similar pattern with the $P_{max}$, curve. Correlation between respiration and $P_{max}$, was not significant (Spearman's rank correlation, p>0.05); respiration rate, which varied between 0.25 and 0.83 mg $O_2{\cdot}gdw^{-1}{\cdot}h^{-1}$, showed no gradual decline from March. $P_{max}$ in situ significantly correlated with the relative growth rate of frond weight (Spearman's rank correlation, p<0.01) and this result means that the amount of accumulated materials in body increased with the increment of $P_{max}$. Compared $P_{max}$, in situ with that in the laboratory. The lower $P_{max}$ in February was probably caused by the effect of lower seawater temperature at this time. The decrease in $P_{max}$ after March, however, was primarily attributable to the thickness of blade as the plants got old. Comparison of P-I parameters measured for different size groups in April, explained the negative relationship between $P_{max}$ and frond thickness.

• Parasites, Hosts and Diseases
• /
• v.29 no.2
• /
• pp.139-148
• /
• 1991

Cryptosporidium, a coccidian protozoa, commonly causes a self-limiting diarrheal illness in humans and animals. Fecal samples from various animals in Chonbuk district were observed using Sheather's aoatation technique, Kinyoun's modified acid-fast staining, and osmic acid pre-fixed Giemsa staining. The oocysts were detected in 74 cages(29.6%) out of 250 cages of mature mice, 26 (13.3%) out of 195 mature house rats, 75 (15.0%) out of 4-week-old 500 fowls, 98(19.9%) out of 6 to 8-month-old 500 pigs, and 111(22,2%) out of 2 to 5-year-old 500 dairy cattle, respectively. The degree of prevalence was slight in general, but actual prevalence was higher than infection rate because the detection rates were higher in repeated-preparation examinations in comparison to the first examination. Meanwhile, large and small types of oocysts were detected from mice, house rats, pigs, and cattle, and midium type from fowls.

• Journal of the Korean Society of Fisheries and Ocean Technology
• /
• v.52 no.3
• /
• pp.183-190
• /
• 2016

This study carried out an experiment to find out the reaction of hairtail, Trichinus lepturus to the colors of LED light as a basic study on the development of the trolling gear and a method to enable the day-night operation. We used hairtails caught around Seongsan-po, Jeju Island by set nets and hairtail angling. The seven hairtails of the average length 68.9 cm (SD 9.2 cm) and the average weight 135.9 g (SD 47.9 g) were adapted themselves in the experimental water tank, 15 m Self-Governing 1.7 m in height and 1.5 m in depth, and then they were studied. We conducted experiment at the Ocean and Fisheries Research Institute in Jeju Special Self-Governing Province, from November to December 2015, and the sea surface temperature was between 16.5 and $19.5^{\circ}C$. The four colors of LED light, blue, white, green and red, were set up to transmit downward from the marginal area of tank. The 1 meter depth light intensity of LED colors is as follows: $0.09w/m^2/s$ (blue), $0.18w/m^2/s$ (white), $0.04w/m^2/s$ (green) and $0.007w/m^2/s$(red) To know the optimum LED color light, we selected one with better reaction rate after comparison of two colors simultaneously and the selected color was again compared to the other color in a tournament style two times a day (day and night) and ten times totally. The reaction rates were shown as the frequencies of hairtail appearance for 5 minutes in the lighting zone after turning on the LED lights. The reaction rate of the blue was at 97% unlike the red 3% (p < 0.001). The blue was at 75% unlike the green at 25% (p < 0.001). The blue was at 67% unlike the white at 33% (p < 0.001). Therefore, the color of light source showing the highest reaction rate was the blue.

• Journal of Acupuncture Research
• /
• v.25 no.4
• /
• pp.51-58
• /
• 2008

Objectives : Sypsun-points are located at the tips of all fingers, 0.1 chon(寸) from the finger nails, totaling 10 points on both hands. These points have been used for emergency care, fainting, epilepsy, cerebrovascular accidents, hypertension, unconsciousness, high fever etc. in oriental medicine. The most common technique is bleeding with a needle at these points. We investigated whether Venesection at the Sybsun-points has effects on blood pressure and body temperature and pulse rate in humans aged from 20 to 30 who had no specific past history and whose vital signs are in normal range. Methods : 67 persons were studied from March to June 2008. They were composed of Sample group(n=36) and Normal group(n=31). Both two groups kept a steady state an hour before venesection. In both group, we checked blood pressure and body temperature and pulse rates 6 times( 30min. before and just before treatment, and just after, 30, 60, 90min after treatment). All study environments were same between sample and normal group. But only, normal group didn't carry out venesection at the Sybsun-points. Results : In a comparison of before and after venesection at the Sybsun-points, any Statistical significance was not evaluated. Though pulse rate in sample group was significantly decreased after venesection(p<0.05), it has no statistical significance because normal group's pulse rate was also significantly decreased and between two groups had no statistical difference. Conclusions : Though further study is needed, our findings suggest that venesection at the Sybsun-points has no significant effect on blood pressure and body temperature, and pulse rate in humans who had no specific past history and whose vital signs are in normal range. Also in that case, we may know that pain and tension result from venesection at the Sybsun-points have no significant effect on blood pressure and body temperature and pulse rate.

• Journal of Korean Society of Occupational and Environmental Hygiene
• /
• v.31 no.1
• /
• pp.60-72
• /
• 2021

Objectives: This study was performed to investigate the level of participation in and satisfaction with training courses at job training institutions and to improve participation and satisfaction through changes in the training method for industrial ventilation subjects. Methods: The results were analyzed for the mean and standard deviation by t-test and ANOVA, (p=0.05). Participation rates were examined for three courses: specialization, job training, and supervisory. The participation inthe education was 428 people, and the result of satisfaction with the change of education method was 878 people. Satisfaction was investigated for the specialized curriculum and job training curriculum,but not the supervisor curriculum. The satisfaction results for six items(contents, quality, skill, level, degree of understanding, degree of practical) were analyzed according to the change in the training medium and the method among people in one occupational ventilation subject. Results: The participation rate was similar in the job training and specialized training courses, but the lowest rate was in supervisory courses(p=0.05). In general, there was the lowest participation on the first day of education, and the participation rate improved after the second day. Satisfaction with the course was high for the specialized education course with a number of practical education assignments(p=0.278). The satisfaction level for the teaching method in the industrial ventilation subjects was high in a mixed group which combined lecture and practice. The industrial ventilation course in the basic job training course showed a difference between lecture and mixed education(p=0.111), but there was no significant difference. However, the industrial ventilation course in the advance job training course showed a clear difference between lecture and the mixed education(p=0.036). Conclusions: Therefore, the first day of training should start in the afternoon so that more trainees can participate, and it is recommended to assign important subjects after two days. In addition, it is suggested that job competency-enhancing education utilize various educational methods and media.