• Title/Summary/Keyword: Comparison analysis

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Gene Set Analyses of Genome-Wide Association Studies on 49 Quantitative Traits Measured in a Single Genetic Epidemiology Dataset

  • Kim, Jihye;Kwon, Ji-Sun;Kim, Sangsoo
    • Genomics & Informatics
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    • v.11 no.3
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    • pp.135-141
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    • 2013
  • Gene set analysis is a powerful tool for interpreting a genome-wide association study result and is gaining popularity these days. Comparison of the gene sets obtained for a variety of traits measured from a single genetic epidemiology dataset may give insights into the biological mechanisms underlying these traits. Based on the previously published single nucleotide polymorphism (SNP) genotype data on 8,842 individuals enrolled in the Korea Association Resource project, we performed a series of systematic genome-wide association analyses for 49 quantitative traits of basic epidemiological, anthropometric, or blood chemistry parameters. Each analysis result was subjected to subsequent gene set analyses based on Gene Ontology (GO) terms using gene set analysis software, GSA-SNP, identifying a set of GO terms significantly associated to each trait ($p_{corr}$ < 0.05). Pairwise comparison of the traits in terms of the semantic similarity in their GO sets revealed surprising cases where phenotypically uncorrelated traits showed high similarity in terms of biological pathways. For example, the pH level was related to 7 other traits that showed low phenotypic correlations with it. A literature survey implies that these traits may be regulated partly by common pathways that involve neuronal or nerve systems.

Comparison of the Stress Concentration Factors for GFRP Plate having Centered Circular Hole by Three Resource-Conserving Methods

  • Gao, Zhongchen;Park, Soo-Jeong;Kim, Yun-Hae
    • Composites Research
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    • v.29 no.6
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    • pp.388-394
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    • 2016
  • Fiber reinforced plastic (FRP) composites have drawn increasing attentions worldwide for decades due to its outstanding properties. Stress concentration factor (SCF) as an essential parameter in materials science are critically considered in structure design and application, strength assessment and failure prediction. However, investigation of stress concentration in FRP composites has been rarely reported so far. In this study, three resource-conserving analyses (Isotropic analysis, Orthotropic analysis and Finite element analysis) were introduced to plot the $K_T^A-d/W$ curve for E-glass/epoxy composite plate with the geometrical defect of circular hole placed centrally. The plates were loaded to uniaxial direction for simplification. Finite element analysis (FEA) was carried out via ACP (ANSYS composite prepost module). Based on the least squares method, a simple expression of fitting equation could be given based on the simulated results of a set of discrete points. Finally, all three achievable solutions were presented graphically for explicit comparison. In addition, the investigation into customized efficient SCFs has also been carried out for further reference.

An Improvement of Evaluation Items for a Subjective Workload Assessment in Nuclear Power Plants (원자력발전소의 주관적 업무량 평가를 위한 평가 항목 개선)

  • Park, Jae-kyu;Lee, Yong-Hee
    • Journal of the Ergonomics Society of Korea
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    • v.29 no.4
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    • pp.687-691
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    • 2010
  • Workload assessment is one of the important elements of the human factors evaluation for the nuclear power plants in operation. This paper describes a further study upon the additional elements of the workload which elements should be considered in the subjective workload assessment. We have tried to predict the burden of the work and to improve the work through a comparison of the objective workload and the subjective workload in the previous studies in nuclear power plants. However, there is a restriction to perform a precise assessment because of the limitations of the method itself. The objective workload assessment is performed by relative comparison using the quadrant analysis with objective workload and subjective workload because there were no clear criteria of objective workload assessment. And the subjective workload assessment is performed by NASA-TLX (NASA Task Load Index) which includes six evaluation dimensions of subjective workload. NASA-TLX is difficult to grasp the other aspects that could influence on the subjective workload because the analysis relies on predetermined assessment items. We conduct a factor analysis between the factors that affect the workload and the assessment adopted from ISO 10075 and NASA-TLX. At the same time, this study suggests other evaluation elements which can be added for subjective workload assessment except for evaluation elements of NASA-TLX.

Aluminum Wire Bonding by Longitudinal Vibration of Ultrasonic Transducer (초음파 트랜스듀서의 종진동을 이용한 알루미늄 와이어 용접)

  • Lee, G.B.;Kim, H.S.
    • Journal of the Korean Society for Precision Engineering
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    • v.13 no.11
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    • pp.38-45
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    • 1996
  • In recent years, ultrasonic has been widely applied in measurement and industrial fields and its application range has been expanded as a result of continuous research and development. Wire Bonding Machine, an instrument fabricating semi-conductor, makes use of ultrasonic bonding method. Specially, the method utilizes the longitudinal vibration of ultrasonic transducer composed of piezoelectric vibrator and horn. This work investigates the design conditions affecting the dynamic characteristics through the theretical and experimental analysis. It conducts separately the system identification of piezoelectric vibrator in time domain and the modal analysis of horn in frequency domain. The integrated modeling is conducted via a combbination of dynamic identification of piezoelectric vibrator and theroretical analysis of horn. Then comparison is made for theroretical and experimental results of the dynamic characteristics of the ultrasonic transducer comprised of piezoelectric vibrator and horn. Form the results of the comparison we develop the design technique of ultrasonic transducer using dynamic characteristics analysis and propose the possibility of ultrasonic bonding considering the optimal conditions for the longitudinal vibration of ultrasonic transducer and other conditions.

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Analysis for foundation moments in space frame-shear wall-nonlinear soil system

  • Jain, D.K.;Hora, M.S.
    • Earthquakes and Structures
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    • v.10 no.6
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    • pp.1369-1389
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    • 2016
  • The soil-structure interaction effect significantly influences the design of multi-storey buildings subjected to lateral seismic loads. The shear walls are often provided in such buildings to increase the lateral stability to resist seismic loads. In the present work, the nonlinear soil-structure analysis of a G+5 storey RC shear wall building frame having isolated column footings and founded on deformable soil is presented. The nonlinear seismic FE analysis is carried out using ANSYS software for the building with and without shear walls to investigate the effect of inclusion of shear wall on the moments in the footings due to differential settlement of soil mass. The frame is considered to behave in linear elastic manner, whereas, soil mass to behave in nonlinear manner. It is found that the interaction effect causes significant variation in the moments in the footings. The comparison of non-interaction and interaction analyses suggests that the presence of shear wall causes significant decrease in bending moments in most of the footings but the interaction effect causes restoration of the bending moments to a great extent. A comparison is made between linear and nonlinear analyses to draw some important conclusions.

Analysis of Papers Published in Thirty Years of the Journal History of The Journal of Korean Acupuncture and Moxibustion Medicine (${\ll}$대한침구의학회지${\gg}$에 30년간 게재된 논문에 대한 관찰)

  • Jang, Su Hee;Oh, Deuk Ju;Park, Jung Ha;Yoon, Myoung Hwan;Choe, Ick Seon
    • Journal of Acupuncture Research
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    • v.31 no.1
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    • pp.35-42
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    • 2014
  • Objectives : Type analysis and comparison among three decades are done on papers published in The Journal of Korean Acupuncture and Moxibustion from the inaugural issue to the last issue of 2013, Vol 30(5). Methods : Journal search engine at 'theacpuncture' and 'kamms' were used. Issues not searched in these two search engines were not included in the analysis. Results : The number of journals in the thirty years of the journal history included 2081 articles. For type analysis of the articles, experiment articles outnumbered other types with 743 papers followed by 564 review articles, 601 clinical articles, and 156 case articles. In comparison among three decades, recent ten years outnumbered the other types with 1060 papers followed by 853 papers in the middle decade and 168 papers at the initial decade. Conclusion : In the thirty years of the journal history, the research has become more actively done in the recent decade.

Comparison of the seismic performance of existing RC buildings designed to different codes

  • Zeris, Christos A.;Repapis, Constantinos C.
    • Earthquakes and Structures
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    • v.14 no.6
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    • pp.505-523
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    • 2018
  • Static pushover analyses of typical existing reinforced concrete frames, designed according to the previous generations of design codes in Greece, have established these structures' inelastic characteristics, namely overstrength, global ductility capacity and available behaviour factor q, under planar response. These were compared with the corresponding demands at the collapse limit state target performance point. The building stock considered accounted for the typical variability, among different generations of constructed buildings in Greece, in the form, the seismic design code in effect and the material characteristics. These static pushover analyses are extended, in the present study, in the time history domain. Consequently, the static analysis predictions are compared with Incremental Dynamic Analysis results herein, using a large number of spectrum compatible recorded base excitations of recent destructive earthquakes in Greece and abroad, following, for comparison, similar conventional limiting failure criteria as before. It is shown that the buildings constructed in the 70s exhibit the least desirable behaviour, followed by the buildings constructed in the 60s. As the seismic codes evolved, there is a notable improvement for buildings of the 80s, when the seismic code introduced end member confinement and the requirement for a joint capacity criterion. Finally, buildings of the 90s, designed to modern codes exhibit an exceptionally good performance, as expected by the compliance of this code to currently enforced seismic provisions worldwide.

Management Evaluation on the Regional Fisheries Cooperatives using Data Envelopment Analysis Model (DEA모형에 의한 지역수협의 경영평가)

  • Lee, Kang-Woo
    • The Journal of Fisheries Business Administration
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    • v.42 no.2
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    • pp.15-30
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    • 2011
  • This study is designed to measure the relative efficiency of regional fishery cooperatives based on Data Envelopment Analysis(DEA) methods. Selecting 40 regional fishery cooperatives in Busan as Decision Making Units (DMUs), the study uses their panel data from 2007 to 2008 to rank the relative efficiency of the DMUs. First, the efficiency score of the DMUs are calculated using CCR, SBM, and super-SMB model. Within the model, input variables are the number of employees and area of fishery cooperatives. Output variables are the amount of deposit money, loan and profit. Based on the efficiency scores calculated from super-SMB model, the efficiency ranking of the DMUs is determined. Second, the differences in average efficiency calculated from the three DEA models are tested using a pair-wise mean comparison test. The results based on the efficiency scores evaluated from super-SMB model show that seven out of the forty DMUs are efficient; among the efficient DMUs, the DMUs that can be benchmarked for inefficient DMUs through the frequency analysis of reference set being identified. Third, the differences in average efficiency of the three DEA models between 2007 and 2008 are tested using pair-wise mean comparison test and the study estimates the efficiency change of the DMUs between 2007 and 2008 using Malmquist productivity index(MPI). Finally, the paper suggests an improved composite DMU superior to the inefficient DMUs evaluated by Super-SBM model.

Effects of Sling Exercise on Balance and Gait in Patients with Stroke: Meta-Analysis of Studies in Korea

  • Cho, Woonsu;Lee, Seongjin;Kim, Byeonggeun
    • Journal of International Academy of Physical Therapy Research
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    • v.11 no.3
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    • pp.2164-2172
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    • 2020
  • Background: Stroke patients have multiple disorders, but most have problems with balance and gait. Post-stroke rehabilitation exercise has been shown to be very important for functional recovery. Objectives: To systematically review and meta-analyze the effects of sling exercise (SE) on patients with stroke in studies published in Korea. Design: Meta-analysis. Methods: Five databases, namely, RISS, KISS, NDSL, DBpia and Earticle, were used to collect articles on vibration. Keywords such as "Stroke," "Hemiplegia," "Sling," and "Sling Exercise" were used in the search for published articles. Interventions and comparisons were SE and other exercise (OE). Outcome measures were berg balance scale (BBS) and timed up and go (TUG). Consequently, eight studies were selected in the second screening using meta-analyses. Results: Based on the results of the meta-analysis, SE was effective for BBS in the comparison of SE and OE [2.71, 95% CI (1.42, 4.01)]. It was effective for TUG in the comparison of SE and OE [-1.89, 95% CI (-3.01, -0.77)]. Conclusion: Based on eight limited studies, SE improved BBS and TUG over OE, suggesting improved stroke balance and gait. Therefore, more studies and large-scale sample randomized controlled trials are needed to confirm clinical application.

Face recognition rate comparison using Principal Component Analysis in Wavelet compression image (Wavelet 압축 영상에서 PCA를 이용한 얼굴 인식률 비교)

  • 박장한;남궁재찬
    • Journal of the Institute of Electronics Engineers of Korea CI
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    • v.41 no.5
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    • pp.33-40
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    • 2004
  • In this paper, we constructs face database by using wavelet comparison, and compare face recognition rate by using principle component analysis (Principal Component Analysis : PCA) algorithm. General face recognition method constructs database, and do face recognition by using normalized size. Proposed method changes image of normalized size (92${\times}$112) to 1 step, 2 step, 3 steps to wavelet compression and construct database. Input image did compression by wavelet and a face recognition experiment by PCA algorithm. As well as method that is proposed through an experiment reduces existing face image's information, the processing speed improved. Also, original image of proposed method showed recognition rate about 99.05%, 1 step 99.05%, 2 step 98.93%, 3 steps 98.54%, and showed that is possible to do face recognition constructing face database of large quantity.