• Journal of Preventive Medicine and Public Health
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• 제35권1호
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• pp.41-48
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• 2002

Objectives : To review the drug prescription pattern of antiulcerative agents for elderly inpatients, Methods : The study population comprised inpatients of community hospitals who were members of the Korean Elderly Pharmacoepidemiologic Cohort (KEPEC), aged 65 years or over, beneficiaries of the Korea Medical Insurance Corporation (KMIC) and residing in Busan city in 1993. The drug prescription information was collected from the claims data of hospitals where the cohort members received medical care between January 1993 and December 1594. The information included personal identification, age, gender, diagnosis, drug dosage, date of hospital admission and name of medical institutions where the study subjects received drug prescriptions. The data analysis produced outcomes in terms of distribution of antiulcerative agents by class and by medical institution and trend of relative prescription, Analysis was also performed in terms of combined prescriptions of antiulceratives and drugs that could induce risk from drug interaction with antiulceratives. Results : The number of patients prescribed antiulcerative agents was 1,059 (64,9%) male and 1,724 (65.5%) female among the total inpatients. An antacid and composite agent was the most frequently prescribed antiulcerative agent (70.8%), followed by $H_2$ antagonist (16.0%), Among the potential drugs that could induce risk from drug interaction with the antiulcerative agents, diazepam was the most frequently prescribed. The proportion of diazepam co-prescription was 22.5% of the total cimetidine prescriptions and 14.5% of the fetal omeprazole prescriptions. Conclusions : Antiulcerative drugs were frequently prescribed in the elderly inpatients. The adverse drug reaction could possibly be due to drug interaction. The study results could be used as fundamental data for further drug utilization review of antiulceratiye agents.

• Tuberculosis and Respiratory Diseases
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• 제67권3호
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• pp.249-253
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• 2009

On 7 December 2007, the Hebei Spirit ran aground near Taean and released approximately 10,900 tons of oil into the sea. Crude oil on the coastal areas and fumes in the air increased the number of health problems among the local population. We report a case of respiratory failure after the oil spill clean-up work. A 66-year-old female was admitted to hospital with cough, sputum, and dyspnea of 1-month duration after the oil spill clean-up. She was diagnosed with community-acquired pneumonia and treated with empirical antibiotics. However, she had progressive respiratory failure without identification of the pathogen. Respiratory failure due to chronic inhalation of hydrocarbons from the crude oil spill clean-up was suspected. After mechanical ventilation care, she recovered from respiratory failure and was discharged. We report a case of severe respiratory toxic effects after an oil spill clean-up. We concluded that long-term hydrocarbon inhalation during the oil spill clean-up may have induced respiratory failure in this case.

• 융합정보논문지
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• 제7권4호
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• pp.27-38
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• 2017

본 연구는 국내 의료기관인증제도와 미국과 호주의 의료기관인증제도 및 국제의료질향상학회의 국제인증프로그램에 대해 비교 고찰함으로써 우리나라 의료기관인증제도의 발전을 위한 시사점을 제시하고자 시도되었다. 본 연구에서 도출된 시사점은 다음과 같다. 첫째, 환자 및 지역사회 중심의 관점 강화, 인력배치 기준 강화 등 의료기관 인증기준의 개선이 필요하다. 둘째, 의료기관인증제도를 통한 환자안전의 강화가 필요하다. 셋째, 의료기관인증제도와 임상질지표 및 환자경험평가 연계를 강화해야 한다. 넷째, 조사위원의 역량을 강화해야 한다. 다섯째, 중소병원의 인증제도 참여 활성화가 필요하다. 여섯째, 의료 질 평가 결과 공개의 강화가 요구된다. 본 연구 결과는 우리나라 의료기관인증제도의 개선을 위한 기초자료로 활용될 수 있을 것이다.

• 농촌계획
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• 제18권3호
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• pp.91-101
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• 2012

The purposes of this study were to identify the living environment in rural fishing area and to suggest checking methods for implementation performance. Rural service standard is the key factor of rural development in Korea. In 2012. The first Implementations of performance was announced. The results were presented to the unit by the City and the County. Because of Fishing villages exists as a unit by the haengjeongri. It is difficult to know the status of the fishing villages by the Rural service standard. In order to look for the actual conditions in rural fishing village it was investigated in the 100 Eochongye. The data used in the analysis is 577 questionnaires. Analysis showed that rural fishing areas were superior to general state of rural in the 8 items of rural service standard. Especially housing, transportation and health care sector in rural fishing area wes better than general state of rural. But Public safety and order is relatively poor. This is because Fishing village contains islands. Presenting to improve rural service standard based on the results of research. The items of rural service standard should be measured the actual residents' accessibility than opportunity of the public service, and after setting the rural service standard clearly related to the quality of life of residents in each sector. Accessibility aspects of the customer for the public services should be considered. Checking the performance for the unit by the City and the County should be replaced as a living zone in order to consider the facilities using nearby.

• 기본간호학회지
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• 제5권2호
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• pp.257-268
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• 1998

The purpose of this study were to identify the characteristics of urinary incontinence in adult women and to identify it's relating factors, daily living and sexual problem related urinary incontinence. Subjects were 60 community dwelling women in the age of 25-60 years old at 1 cities in Korea. The data were collected from January 1988 to May. 1998. Subject were interviewed with structured questionnaire. Questionaire was composed of item of general characteristics, obstetrical characteristics, measuring tool of severity of urinary incontinence, discomfort due to urinary incontinence. The data were analyzed with SAS program, descriptive statistics, T-test, ANOVA test. The results of study were as followings. 1) Most of incontinence women were mildly incontinent subjects(mean=7.40). 2) The common activity related to the urinary incontinence were coughing, sneezing, laughing aloudly exercising. 63.5% of women reported small volume accidents of only 1 to 2 drops. 3) The incidence of urinary incontinence was significantly higher in woman who had more pariety and older age of last delivery, menopause, itching sense of vagina. 4) 73.3% of the episodic urinary incontinence were not treated because the felt that urinary incontinence was not disease(70.4%) was shamful(18.1%), was incurable inspite of treatement attempt(4.5%). 5) Daily living problem related to urinary incontinence were as follows : Voiding before going out(66.6%), odor of urine(10.0), frequent underwear change.(88.3%). 6) Sexual intercourse problem related to urinary incontinence were as follows : Pain during sexual intercourse(30.0%), sexual life trouble,(8.3%), urine leakage.(11.7%) The results indicate that urinary incontinence is common in adult women. Health care provider should develop and provide adequate nursing intervention for prevention and early treatment of urinary incontinence.

• 국제지역연구
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• 제16권3호
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• pp.367-390
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• 2012

본 논문은 20대 병영생활을 하는 인적자원들이 2년의 복무기간동안 보다 효율적인 시간관리와 정신적 육체적 건강관리를 통해 사회에 환원될 수 있도록 군복무에 대한 만족도에 군 인트라넷이 어떤 영향을 미치는 지에 대한 실상을 분석하는데 목적이 있다. 이는 개인적으로나 국가적인 차원에 있어 군복무의 효율적인 운영이라는 차원에서 시사하는 바가 매우 클 뿐만 아니라 향후 신세대 예비 군복무자들에게 있어 자기관리에 필요한 유용한 정보를 제공할 수 있는 지침이 되기 때문이다. 본 연구는 인터넷 세대로 이루어진 20대 초반의 신세대 장병들에게 군 인트라넷이 군복무 만족에 어떤 영향을 미치는지 그 요인을 분석하는 동시에 아울러 이것을 군조직 차원에서 효율적인 활용을 위해 정보를 제시하는데 그 의의를 두고자 한다. 결론적으로 인트라넷은 복무만족에 효과적으로 영향을 미치는 중요한 요인이자, 수단이라는 것이 입증되었으며 나아가 군조직에서 적용되고 있는 인트라넷 망을 단순업무나 전파수단이 아닌 조직의 전략과 목표달성을 위해 보다 한 차원 높은 군 인트라넷 활용으로 발전시켜야 한다는 시사점이 도출되었다.

• 노인간호학회지
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• 제20권sup1호
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• pp.119-126
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• 2018

Purpose: The aim of this study was to describe problems and solutions for older adults living alone and using wearable devices to report depressive moods in daily life. In addition, gerontology nurses' competencies and strategies were discussed based on lessons learned from the observational study. Methods: A hybrid method was used, combining literature review and content analyses based on interviews with 53 participants and observations done by the research team. Results: Main issues and relevant strategies were identified in terms of (1) applicability of information and communications technology (ICT) devices for older adults, (2) feasibility of older adults' use of ICT devices, (3) integration of ICT devices into daily life, and (4) relevant issues when older adults use ICT. Important roles and competencies were discussed regarding general and gerontology aspects of ICT. Conclusion: Findings indicate that a wearable device is feasible to measure daily depressive moods in older adults living alone in community settings. To extend our research protocol to practice, gerontology nurses must adequately prepare to meet emerging health care trends and end users' needs for ICT-based nursing. It is necessary to develop diverse educational programs and active involvement in research and design of relevant devices and programs.

• 한국융합학회논문지
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• 제11권12호
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• pp.309-317
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• 2020

포스트코로나 시대를 맞이하여 원격의료의 중요성이 커지고 있다. 이에, 본 연구는 우리나라와 의료체계가 비슷하고 이미 시행하고 있는 일본의 원격의료에 관한 추진과정, 현황 및 과제 등을 분석 하였다. 더불어 향후 국내 원격의료의 도입 확대를 위한 실효성 있는 방안마련과 정책적 시사점을 모색함에 있다. 일본은 의료계에서 원격의료도입의 필요성을 주장함에도 원격의료 정착화까지 신중한 태도로 제도화하고 있다. 반면 우리나라는 원격의료의 진료수가에 대한 명확한 규정 및 의료과실에 대한 책임소재에 관한 법적인 조치가 부족한 상황이다. 따라서 원격의료의 주체에 대한 명확한 법적인 해석이 필요하며, 의사와 환자의 법적 책임과 한계에 대한 지침 및 대책을 강구하는 등 전략적 접근이 우선적으로 필요할 것이다.

• BMB Reports
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• 제55권11호
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• pp.547-552
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• 2022

Sorafenib, originally identified as an inhibitor of multiple oncogenic kinases, induces ferroptosis in hepatocellular carcinoma (HCC) cells. Several pathways that mitigate sorafenib-induced ferroptosis confer drug resistance; thus strategies that enhance ferroptosis increase sorafenib efficacy. Orphan nuclear receptor estrogen-related receptor γ (ERRγ) is upregulated in human HCC tissues and plays a role in cancer cell proliferation. The aim of this study was to determine whether inhibition of ERRγ with DN200434, an orally available inverse agonist, can overcome resistance to sorafenib through induction of ferroptosis. Sorafenib-resistant HCC cells were less sensitive to sorafenibinduced ferroptosis and showed significantly higher ERRγ levels than sorafenib-sensitive HCC cells. DN200434 induced lipid peroxidation and ferroptosis in sorafenib-resistant HCC cells. Mechanistically, DN200434 increased mitochondrial ROS generation by reducing glutathione/glutathione disulfide levels, which subsequently reduced mTOR activity and GPX4 levels. DN200434 induced amplification of the antitumor effects of sorafenib was confirmed in a tumor xenograft model. The present results indicate that DN200434 may be a novel therapeutic strategy to re-sensitize HCC cells to sorafenib.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제49권1호
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• pp.21-29
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• 2023

Objectives: Dental or maxillofacial emergencies are uncommon during pregnancy, but if they occur, they are challenging to treat due to potential risks. The mother should not be denied necessary medical or dental care because of pregnancy. The aim of the study is to observe outcomes of pregnancy in patients requiring emergency minor oral surgical procedures during gestation and to determine the safety of the pregnant woman undergoing the procedure and the fetus. Materials and Methods: The study was conducted on 52 pregnant women requiring emergency oral surgical procedures. A standard treatment protocol for treatment of specific entities was followed. Close monitoring and observation were the primary goal of treatment. All patients were followed postoperatively until complete recovery from the surgical procedures and then until birth of the baby. A control group of 52 healthy pregnant patients who did not require oral surgical procedures was considered for statistical analysis. The measurements to calculate observation were fetal loss (spontaneous abortion), preterm birth, low-birth weight, or incidence of any congenital anomalies in the baby and its association with surgical procedures. Results: No fetal loss occurred in any of the cases. However, four patients experienced preterm birth and seven neonates exhibited low birth weights. No congenital abnormalities were discovered. In one instance, a patient who underwent surgery for a mandibular symphysis fracture under general anesthesia in the 31st week of pregnancy experienced labor pain on the fourth postoperative day, requiring an emergency Caesarean section. Conclusion: The results of our study demonstrate that, compared to the control group, minor emergency surgeries performed during pregnancy have no discernible negative effects on the fetus. These procedures can safely be performed by adhering to our described protocols.