• Journal of the Korean housing association
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• v.20 no.4
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• pp.79-88
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• 2009

A planned access method on constantly-changing-community unit plan changes and develops based on the periodical situation and also plan theory. In this research, it is to present the link between the theory of complex city change and the plan factor of it, and to show how Korean residential complex plan has changed as time passed and how new concept of city plan came up and by applying new methods how can this affect our real world and the past plan. In the phase of analysis, it analyzed the flow of 'community unit plan' and its theory and investigated the factor of compositional space and built a analysis frame. The factors of community unit plan are space structure, size and shape of block, population, distribution of facilities and movement system. It chose the place that can represent the flow of community unit plan trand and that indicates the obvious development leading to Jamsil (1975), Gwa Chun (1980), Mok Dong (1983), Sang Ge (1985), Ilsan (1989), Dong tan (2001) and Eun Jung (2003) total of 7 places. And to compare a similar size of the city, it selected a small community unit. Based on the result of theoretical study and prior research, it can be said that the space composition style has change from a whole complete complex area to a linked-cross over community unit and the access of urban level was on set. Also, a pedestrian walking area was secured and the dense of building structure and pleasant environment wanting need was in balance. For facility plans, the usage of facility and functional change brought change of type, size and disposition. The walking area for pedestrian became a huge matter. Therefore, market, education, public facilities and green system collaborated to co-build a whole community unit and activated the walking environment. Also, public transportation, environment friendly city organization was built.

• Journal of the Korean Institute of Rural Architecture
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• v.9 no.2
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• pp.87-94
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• 2007

The recent change of social environment has influence on the configuration of space for the community social welfare center. And so the relation of space and the service function required the change of spatial configuration. The social welfare center fills the role of family welfare, domiciliary care, community service etc. In such sense, this research explore the conditions of spatial configuration for the community welfare service unit of social welfare center in small city. For this study, it was investigated the space role and service function, the service program, the usage characteristics, the room satisfaction of social workers. In sum, the useful data were collected, analyzed, and colligated by case study. It could be used in the basic design criteria of community service unit for the social welfare center in small city.

• Journal of Korean Home Economics Education Association
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• v.2 no.1
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• pp.101-110
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• 1990

The purpose of this study is to survey the learner’s need achievement, interest and practical level of the learning objectives according to the teacher’s teaching method in home economics of middle school(Dietary Life Unit), to examine the differences according to the local situation, and to get some information to improve the teaching method. This study surveyed the eight units of dietary life with 459 students in the rural community (224 students) and Seoul(235 Students). The collected data were analyzed by T-test, F-test. To sum up this study are as follows: 1. When the need, achievement, interest and practical level of unit “food”are compared the students of seoul with those of rural community, the student of Seoul show high in “The use of Processed Foodstuffs” and low in “Cooking the Processed Foodstuffs.”The student of rural community show in “A kind of Cooking Method”and low in “Environment and Food Life”. 2. The need, achievement, interest, practical level of the whole unit in rural community is higher than those is Seoul. 3. According to teaching method, comparison Seoul with rural community is revealed as follows. Seoul region is revealed significance to discovery learning in “Cooking Foodstuffs(The achievement and interest level) and ”Environment and Food Life”(interest level). Rural community is revealed significance to discussion learning in “The constituent and Food Life”(The need level, interest level). Rural community is revealed significance to explanation learning in “Environment and Food Life”(The achievement level).

• Mass Spectrometry Letters
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• v.11 no.4
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• pp.113-117
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• 2020

Cytochrome P450 2J2 (CYP2J2) is a member of the cytochrome P450 superfamily, and is known to be arachidonic acid epoxygenase that mediates the formation of four bioactive regioisomers of epoxyeicosatrienoic acids (EETs). CYP2J2 is also involved in the metabolism of drugs such as albendazole, astemizole, danazol, ebastine, and terfenadine. CYP2J2 is highly expressed in the heart and cancer tissues. In this study, the inhibitory potential of ten natural products against CYP2J2 activity was evaluated using human liver microsomes and tandem mass spectrometry. Among them, bilobetin, which is a kind of biflavonoid, exhibits a strong inhibitory effect against the CYP2J2-mediated astemizole O-demethylation (IC50 = 0.73 μM) and terfenadine hydroxylation (IC50 = 0.89 μM). This result suggests that bilobetin can be used as strong CYP2J2 inhibitor in drug metabolism study.

• Mass Spectrometry Letters
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• v.13 no.4
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• pp.152-157
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• 2022

Schisandra chinensis and its fruits have been used as a traditional herbal medicine to treat liver dysfunction, fatigue, and chronic coughs. Several in vitro and in vivo studies suggested that dibenzocyclooctadiene lignans present in Schisandra fruits strongly inhibit CYP3A4 activity. However, reports on the inhibitory potential of dietary Schisandra supplements against CYP3A activity are limited despite their increasing consumption as dietary supplements. In this study, we evaluated the CYP3A-inhibitory potential of four dietary Schisandra supplements in human liver microsomes. At a concentration of 0.05 mg/mL, Schisandra supplements from Nature's Way, Swanson, Planetary Herbals, and Only Natural inhibited CYP3A activity by 93.9, 70.8, 33.6, and 24.8%, respectively. Nature's Way, which exhibited the strongest inhibition against CYP3A, had the highest contents of gomisin B and gomisin C, which potently inhibit CYP3A activity. The in vivo pharmacokinetics of this product should be examined to determine whether the clinical relevance of inhibiting CYP3A activity by dietary Schisandra supplementation.

• Mass Spectrometry Letters
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• v.12 no.2
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• pp.53-58
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• 2021

Previous in vitro studies have demonstrated that ginsenoside Rc inhibits UGT1A9, but there are no available data to indicate that ginsenoside Rc inhibits UGT1A9 in vivo. The effect of single and repeated intravenous injection of ginsenoside Rc was evaluated on the pharmacokinetics of mycophenolic acid. After injection of ginsenoside Rc (5 mg/kg for one day or 3 mg/kg for five days), 2-mg mycophenolic acid was intravenously injected, and the pharmacokinetics of mycophenolic acid and mycophenolic acid-β-glucuronide were determined. Concentrations of mycophenolic acid and its metabolite from rat plasma were analyzed using a liquid chromatography-triple quadrupole mass spectrometry. Single or repeated pretreatment with ginsenoside Rc had no significant effects on the pharmacokinetics of mycophenolic acid (P > 0.05): The mean difference in maximum plasma concentration (C_max) and area under the concentration-time curve (AUC_inf) were within 0.83- and 0.62-fold, respectively, compared with those in the absence of the ginsenoside Rc. These results indicate that ginsenoside Rc has a negligible effect on the disposition of mycophenolic acid in vivo despite in vitro findings indicating that ginsenoside Rc is a selective UGT1A9 inhibitor. As a result, ginsenoside Rc has little possibility of interacting with drugs that are metabolized by UGT1A9, including mycophenolic acid.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.9
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• pp.4801-4805
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• 2012

This qualitative research within the project entitled "Multiprofessional Intervention and training for Ongoing Volunteer-based Community Health Programs in the Northeast of Thailand (MITV-NET)" was aimed at explaining changes of health behavior of community people in the Northeast after the intervention. The participants comprised 15 community volunteers and 27 villagers. Data were collected by indepth interview, focus group discussion, participation and non-participation observation, and note taking. Analyses were conducted in parallel with data collection, through content and comparative analysis. It was found that the health behavior fell into 2 categories: easy-to-change. The former involved fun activities joined by community people that improved their health or made them recover from illnesses after a short period without becoming addicted. These activities could be done by themselves, for example, exercising and cooking. The difficult-to-change health behavior is habitual, for example, chewing betel nuts or eating uncooked food. The following factors were found affecting behavioral changes: 1) underlying disease; 2) enjoyment in doing activities; 3) habitual behaviour; 4) improved health in a short period; 5) ability of community leaders and volunteers; and 6) community health-supporting resources. It is suggested that improving people's health requires cooperation of community people through fun activities and some initial external support. People who persist in bad habits should be encouraged to stop by showing them health deteriorating effects.

• Korean Journal of Environment and Ecology
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• v.31 no.2
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• pp.202-219
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• 2017

The purpose of this study was to analyze the community structure of forest vegetation in Mt. Geumsusan belong to Woraksan National Park for providing basic information of ecological management. Data were collected by 41 plots from June to November in 2016 using Z-M phytosociology method, which was analyzed with vegetation types, mean importance value and coincidence method. As the results, the forest vegetation was classified into Quercus mongolica community group including Cornus controversa community, Castanea crenata community(Vegetation unit 3), Quercus variabilis community(Vegetation unit 4) and Q. mongolica community(Vegetation unit 5). C. controversa community was divided into two groups such as Ulmus davidiana var. japonica group(Vegetation unit 1) and Parthenocissus tricuspidata group(Vegetation unit 2). Mean importance percentage of vegetation unit 1 was showing Fraxinus rhynchophylla 14.9%, Morus bombycis 8.7% and Acer pictum subsp. mono 8.3%, that of unit 2 was Larix kaempferi 23.2%, C. controversa 20.1% and P. tricuspidata 6.5%, that of unit 3 was Q. mongolica 15.8%, C. crenata 13.4% and F. rhynchophylla 9.8%, that of unit 4 was Q. mongolica 26.6%, Q. variabilis 20.8% and Pinus densiflora 16.7%, that of unit 5 was Q. mongolica 48.3%, Styrax obassia 7.5%, F. rhynchophylla 5.3% in the order, respectively. Each vegetation unit was classified with dependance on environmental factors as 700m of altitude, $20^{\circ}$ of slope degree, middle slope of topography, 20% of bare rock, 30 taxa of present species, 80% of tree layer coverage rate and 20m of tree layer height. In conclusion, it was preferentially considered that development of peculiar and specific management methods with vegetation unit classified above should be needed for ecological and sustainable forest vegetation management.

• Research in Community and Public Health Nursing
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• v.11 no.1
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• pp.67-79
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• 2000

In recent years, the recipients of the services of the health centers in Korea have been shifted from individual sick persons to families as a unit. As a result, the home visiting care records which are all filled out manually, will be increased. Since there is virtually no increase in the number of community health nurses, the CHNs are required to work more efficiently. One of the ways to make the CHNs' work more efficient is to reduce recording time by using a computer. However, a computer system that can manage the families as a unit has not yet been developed. In response to this need, we developed a database system that can be utilized in home visiting care service. The family assessment data is collected. diagnosed. and evaluated according to the family diagnosis classification. The system for family diagnosis consists of seven areas. Those areas are family structure. maintenance of the family system, interaction and interchange. support. coping and adaptation, health management. and housing environment. The areas of the family diagnosis consists of 99 items in all. We expect the following from this system. First. the CHNs will be able to identify family problems more easily. Second. the community's health level can be confirmed by the statistics the system produces. Thirdly, the CHNs' nursing services will be cost effective via reduced recording time. Finally, the family problems of the sick individuals which have been neglected under the health system oriented on individual persons can be effectively managed.

• Journal of The Korean Society of Agricultural Engineers
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• v.63 no.4
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• pp.97-104
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• 2021

Despite the practical limitations of calculating the amount of inflow and supply related to the operation of agricultural reservoirs, the role of agricultural reservoirs is gradually being emphasized. In particular, as interest in disaster safety has increased, the demand for preliminary measures to prepare for disasters has been rising, for instance, pre-discharging agricultural reservoirs for flood control. The aim of this study is to analyze the plans for the flood season reservoir operation considering pre-discharge period and water level limit. Accordingly, we optimized the simulation of daily storage using the ratio correction factor (RCFs) and analyzed the amount of inflow and supply using K-HAS. In addition we developed the drought determination coefficient (k) as a indicator of water availability and applied it for supplementing the risk level criteria in the Drought Crisis Response Manual. The results showed that it would be difficult to set the water level limit during the flood period in the situation of little water supply for flood control in agricultural reservoirs. Therefore, it is necessary to operate the reservoir management regulations after measures such as securing additional storage water are established in the future.