• Tuberculosis and Respiratory Diseases
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• v.46 no.6
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• pp.869-878
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• 1999

Intravesical instillation of the bacillus Calmentte-Gu$\acute{e}$rin(BCG), an attenuated strain of Mycobacterium bovis, is an approved method for the treatment of superficial bladder cancer. Because BCG is a living organism, the potential for infection exists. BCG is generally well tolerated, with complications in less than 5% of those treated with use of current practices. The most frequent symptoms of toxicity associated with intravesical BCG immunotherapy include bladder irritation, frequency, and dysuria. Systemic reactions are less common but more serious than local side effects, and include fever, chills, malaise, rash, hepatitis, pneumonitis, arthritis and sepsis. In rare cases, BCG treatment can result in a systemic infection that requires antituberculous therapy. The pulmonary toxicity that results from intravesical BCG treatment is generally characterized by one of two types : systemic allergic reaction with pulmonary reticulonodular opacities depicted on chest radiographs with cellular findings consisting of activated lymphocytes, and actual BCG mycobacteremia with a miliary pattern depicted on chest radiographs and granuloma formation which rarely results in positive acid-fast stain or culture results. Recently we experienced two types of pulmonary complications following intravesical BCG immunotherapy in patients with superficial bladder cancer. We report two cases with a review of literatures.

• Parasites, Hosts and Diseases
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• v.34 no.1
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• pp.15-20
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• 1996

Cysts of Entamoebn histoIMtica are still found from humans in Korea, but notall of the cysts are known as pathogenic. The non-pathogenic strain is regarded as a differenL species, E. nispnr. In this study, Korean isolates of conventional E. histolvticn were subjected for the differentiation by polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP) analysis. Human stools were screened by routine microscopic examination, and cyst or trophozoite positive stools were inoculated into Robinson media. The cultivated trophozoites were prepared for DNA extraction, and the DNAs were used for PCR with common primers of Pl gene. The PCR products were divested with 3 restriction enzymes and RFLP was observed. Also anti-sense primers containing the cleavage site of each restriction eWe were designed for differentiation only by PCR. The PCR products of Korean isolates 59,512, YS-6, and YS-27 were spliced by Taq I and Xmnl but not byAccl, and the isolates S1, S3, S11, S15, S16, S17, S20, YS- l7, and YS-44 were spliced by Acc I but not by Taq I and Xmn I. These RFLP pattern correlated well with PCR products by the species specific primers. The findings confirm that the Korean isolates 59,512, YS-6, and YS-27 are E. histolwtico and others are E. dispar. In Korea, most of the asymptomatic cyst carriers are infected by E. dispar, not by E. histolytica. Key words: Entcmoebc histolytica, Entcmoebn dispar Korean isolates, polymerase chain reaction (PCR), restriction fragment length polymorphism (RFLP)

• Clinical and Experimental Reproductive Medicine
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• v.1 no.1
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• pp.1-14
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• 1974

Data from this study support the View that the following factors are not sufficiently important in Korea to invalidate the relationships observed between age of marriage and fertility: (1) Premarital pregnancy and common law marriage, (2) shortening of birth intervals in late marriages, (3) adverse effects of very eary marriage in reproductive capacity, and (4) postponement of first pregnancy among early marriages. Thirteen variables which were considered to be potential predictors of fertility were studied to determine their influence on three indices of fertility. Age of marriage and family planning praetice are the strongest predictors and account for about 10% and 7% of the total variance, respectively. Seven other factors each account for an intermediate amount of variability; these are ideal number of children, rural versus urban study area, education, aspiration for daughter, index of exposure to mass media, economic index of respondent's home at survey, and residence before marriage. The remaining variables have no consistently significant relationship to fertility. Most of the relationships appear to be stable and consistent over time; others appear to be changing. The latter group include those variables which are associated with modernization indices of family planning practice, mass media exposure. and aspiration for daughters. Thus, the index of family planning practice is of limited significance for the $40{\sim}49$ age group but is the most important variable for the $20{\sim}29$ year women. The relationship is a direct one for the two age groups between 30 and 49 years which suggests that these groups already had high fertility when family planning services became available and that this high fertility then became an inducement to acccept contraception. The pattern of relationship is not yet clear for the $20{\sim}29$ year group. Similar interactions are observed for the other indices of modernity and are discussed. The thirteen variables together can account for a maximum of about 40% of the variance in the number of live births in the age group $30{\sim}39$, and for lesser amounts of variance in other age and fertility groupings.

• Korean Journal of Plant Resources
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• v.17 no.2
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• pp.107-115
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• 2004

To develop universal primers for phylogenetic analysis and species-specific marker for breeding program of kiwifruit, eighteens primers were designed from kiwifruit genome-specific repeat sequences. Seven species including twenty two varieties collected from native eastern Asia were examined using 18 to 22 mer kiwifruit target(KT) primers. among eighteen primers, we selected seven primers for phylogenetic relationship. The genus Actinidia was divided into two large groups; group I,A. arguta, A. melanandra, A. kolomikta, and A. marcrosperma, characterized by the non-hair in fruits and loaves or a few pubescences only in young stage, which belongs to the section Leiocarpae, and group II, A. chinensis, A. deliciosa, and A. eriantha, characterized by a lot of hairs only in young fruit stage and with a lot of hairs or fuzzes in leaves and branches, which belongs to the section Stellatae. Group II especially belongs to the series Perfectae of the section Stellatae and was divided into two subgroups; subgroup I containing A. chinensis and A. deliciosa, and subgroup II containing A. eriantha. In contrast, the two species, A. chinensis and A. deliciosa, which are known to have common parents, were divided into two independent subgroups with 80％ of a similarity value. On the other hand, we selected KT6F for variety specific bands, KT12E primers for 'Hayward' and 'Tomuri'. KT7F or KT12F primers were useful for analysis of inheritance pattern in kiwifruit cross-breeding. We suggest that these primers will be a powerful tool for elucidating phylogenetic relationship and selection of novelty kiwifruit in a breeding program.

• Journal of KIISE
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• v.42 no.12
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• pp.1535-1543
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• 2015

The brain-computer interface obtains a user's electroencephalogram as a replacement communication unit for the disabled such that the user is able to control machines by simply thinking instead of using hands or feet. In this paper, we propose a feature extraction method based on a non-selected filter by SBCSP to classify motor imagery EEG. First, we divide frequencies (4~40 Hz) into 4-Hz units and apply CSP to each Unit. Second, we obtain the FLD score vector by combining FLD results. Finally, the FLD score vector is projected onto the optimal plane for classification using PCA. We use BCI Competition III dataset IVa, and Extracted features are used as input for LS-SVM. The classification accuracy of the proposed method was evaluated using $10{\times}10$ fold cross-validation. For subjects 'aa', 'al', 'av', 'aw', and 'ay', results were $85.29{\pm}0.93%$, $95.43{\pm}0.57%$, $72.57{\pm}2.37%$, $91.82{\pm}1.38%$, and $93.50{\pm}0.69%$, respectively.

• Korea journal of population studies
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• v.21 no.1
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• pp.105-128
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• 1998

There are about 5,300,000 overseas Koreans in the world. This is about 11.8 percent of the total population of the Korean peninsular. They reside in more than one hundred nations. This exodus occurred due to forced emigration, escape from oppressive regimes, and economic opportunity. Most of them are living in the four regions, that is, China, Japan, America, and Central Asia. The purpose of this paper is to examine the pattern of Korean migration to overseas and to compare the life style of overseas Koreans. The data are taken from a sample survey, which was conducted in China, Japan, America, and Central Asia. A total of 300 respondents were interviewed in each country. The result shows that there are some differences in the lives of overseas Koreans. For example, the Koreans in Central Asia may have suffered the greatest hardship, the similar case was found in the Koreans in China. By contrast, the issue of ethnic conflict becomes the most serious problem in the Koreans in Japan. This study also shows many aspects of common Korean heritage, that is, hard work, diligence, and high level of education. In addition, the study indicates that overseas Koreans are trying to retain Korean traditional values and relationships in their families.

• Conservation Science in Museum
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• v.19
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• pp.53-68
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• 2018

Hanging scrolls and handscrolls are common mounting for East Asian painting and calligraphy in which wooden Chukmok with Chukdu of various materials are attached either at the top and bottom or at each side of a work. Hanging scroll paintings or calligraphy can be hung for appreciation and rolled up for preservation. The Chukmok and Chukdu of a hanging scroll were made from different materials and were known by distinct names in Korea, China, and Japan. In Korea, the wooden Chukmok were called sanghachukhoengmok(上下軸橫木), which means horizontal wooden bars for the top and bottom axes. The wooden Chukdu were called Chukdu(軸頭), meaning the head of an axis. These Chukmok and Chukdu were made of Korean red pine, nut pine, or shiny xylosma. In China, the rod was called zhougan(軸杆) and zhoutou(軸頭), and they were made of Japanese cedar, sappan wood, or red sandalwood. In Japan, the top rod was called hassou(八双; 八裝) and the bottom jikugi(軸木), and they were made of Japanese cedar, red sandalwood, or crystal. In Korean hanging scrolls, the cross section of a Chukdu is either flat or round, and it can be either patterned or patternless. The designs include concentric circles, two circles, and three circles. Among the portraits of meritorious subjects analyzed in this study, three examples feature concentric circles on Chukdu with a flat cross section, which coincides with most of the king's instructions housed at the Jangseogak Archives. This suggests that flat Chukdu with a concentric circle pattern were used for binding most of the paintings of meritorious subjects commissioned by the royal court.

• Korean Journal of Weed Science
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• v.18 no.1
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• pp.12-19
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• 1998

The pattern of rice cultivation in Korea is changing from hand transplanting and machine transplanting into direct-seeding for low input and cost-down practices. However, there are still some obstacles to establish the direct-seeding cultural practices because of poor seedling stand, lodging, and weed infestation. In particular, there were much more and wide weed occurrence in direct-seeding rice as compared with the transplanted rice. Weed occurrence in terms of dry weight of weeds was highest in dry direct-seeded rice followed by sowing an puddled soil, sowing on submerged soil in order as compared with transplanting with infant rice seedling. Echinochloa crux-galli was a common dominant weed with 35~44% distribution in any direct-seeding methods. The dominant weed species were E. crux-galli, Cyperus difformis, C. serotinus, and Ludwigia prostrata in dry-seeded rice. The dominant weed species in water-seeded rice were E. crus-galli, Eleocharis kuroguwai, Scirpus juncoides, and Monochoria vaginalis. Yield loss of rice due to weeds at weedy condition was 96% in dry direct-seeded rice. In water-seeded rice, yield loss was 61%, whereas yield loss was 40% in machine transplanting with infant rice seedling.

• Food Science of Animal Resources
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• v.36 no.6
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• pp.779-786
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• 2016

This study aimed to evaluate the prevalence of Listeria monocytogenes on livestock farms in Korea and determine their serotypes and genetic correlations. Twenty-five livestock farms in Korea (central: 15, south west: 7, south east: 3) were visited 2-3 times, and 2,018 samples (feces: 677, soil: 680, silage: 647, sludge: 14) were collected. Samples were enriched in LEB (Listeria enrichment broth) and Fraser broth media, and then plated on Palcam agar. The isolates were identified by PCR and 16S rRNA gene sequencing. Then, the sero-types, presence of virulence genes (actA, inlA, inlB, plcB, and hlyA), and antibiotic resistance were determined. Genetic correlations among the isolates were evaluated by analyzing the restriction digest pattern with AscI. Of the 2,018 samples, only 3 (0.15%) soil samples (FI-1-FI-3) from 1 farm in the south east region were positive for L. monocytogenes. Based on biochemical tests and multiplex PCR, the serotype of the isolates were 4ab (FI-1 and FI-3) and 3a (FI-2), which are not common in foodborne L. monocytogenes. The 3a sero-type isolate was positive for all tested virulence genes, whereas the 4ab serotype isolates were only positive for hlyA, actA, and inlA. The isolates were resistant to all 12 tested antibiotics, especially FI-3. The genetic correlations among the isolates were 100% for those of the same serotype and 26.3% for those of different serotypes. These results indicate that the prevalence of L. monocytogenes on livestock farms in Korea is low; however, the isolates are pathogenic and antibiotic resistant.

• The Korean Journal of Quaternary Research
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• v.5 no.1
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• pp.15-31
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• 1991

A total of 90 surface sediment samples, collected from the continental margin area bordering east and southeast coast of Korea, were subject to the geochemical analyses with the aim of filling the gap in our knowledge of this environment. The analyzed items included the major elements (Al, Fe, Mg, Ca, K, Na, p and Mn), organic carbon, and some trace metals (Ba, Co, Cu, Sr and Zn). The sediment grain-size exerted a predominant influence on the contents of most elements, with the exceptions of Ca, K, Sr and Ba. The Ca and Sr contents, being closely interrelated each other, were mainly controlled by the calcium carbonate content. The K content, on the other hand, appeared to be influenced by both illite and feldspar. The Ba content showed a certain relationship with that of K, suggesting a common source of these two elements; potassium feldspar. The R-mode factor analysis result also reaffirmed the above-mentioned controlling factors on the sediment geochemistry. The grain-size dependency of trace metals obscures their areal distribution pattern from the total contents. However, with the metal/aluminum ratios we could differentiate the subtle difference in the metal enrichment. Hence, sediments of the southern coastal area appear to receive some anthropogenic inputs of metals, though the effect is still negligible.