• Child Health Nursing Research
• /
• 제8권1호
• /
• pp.55-66
• /
• 2002

It is an important task to give adequate nutritions to infants and to wean properly for rapid growth. This study was conducted to survey on doing the weaning activities of the first-time mother. This study was to provide basic data of health teaching and nursing intervention for the promotion of ideal weaning activities. Survey was done from January to February in 2001. Total 444 mothers who have first-time baby under twelve month old were interviewed in five community health center around contry (Seoul, Choung-ju, Asan, Cheon-an, Jeju). The results are summarized as follows; Starting time of weaning was common in four month old(40.4%). Most common daily weaning times by age showed once(under 3 months), twice(4 to 7 months), three times(8 to 12 months). The younger, the more commercial weaning products(p<0.01). Education level showed relatively positive relation with home-made weaning food(p<0.05). Items showed low scores in 4 to 7 months group were starting new food item, waiting at least one week interval to new food, feeding by milk bottle, allowing grasping spoon, consulting pediatrician for problems after weaning, starting from morning, regular schedule. Items showed low scores in 8 to 12 months group were feeding whole egg rather than yolk only up to 12 months, keeping weaning interval were increased, feeding by milk bottle, trying various cooking method, not giving commerical cooking and instant food and unproper raw milk feeding. In weaning activities by general factors, mother age, health status, marriage duration, monthly income were statistically significant (p<0.05). To improve good weening activities, targetting on low maternal age and poor health status, and low income group, developing teaching materials and training program for items showed low scores and proper weaning time, type of easy home-made food and easy cooking method should be provided. Further study on effect of nursing intervention to improve weaning activities are needed.

• KSBB Journal
• /
• 제22권5호
• /
• pp.351-355
• /
• 2007

포도즙 착즙 후 폐기되는 포도송이가지를 재활용하여 항산화 물질로 잘 알려진 resveratrol을 80% 에탄올로 초음파 추출기를 이용하여 60분 동안 추출한 후 실리카겔 컬럼을 적용시켜 99% 이상의 순도로 정제하였다. 정제된 resveratrol의 안정성은 4$^{\circ}C$에서는 반감기가 90일이었으며, 25$^{\circ}C$에서는 60일로 조사되었다. 또한 고순도 resveratrol 추출물을 적용하여 기존의 식품에 포함된 양의 2$\sim$10배 정도 강화시킨 포도즙의 관능평가를 수행한 결과 전반적인 기호도가 높았으며, 색, 향 및 당도는 일반 포도즙에 비해 유의적인 차이가 없었다. 앞으로 포도착즙의 부산물인 포도송이가지에서 추출된 resveratrol은 건강보조식품, 기능성 향장품 소재 등으로 활용가치가 높을 것으로 사료된다.

• Journal of Oral Medicine and Pain
• /
• 제41권4호
• /
• pp.155-160
• /
• 2016

Purpose: It has been reported that xylitol and sorbitol affect antifungal activities by enhancing antimicrobial activities of other substances. The purpose of this study was to investigate the direct candidacidal activities of xylitol and sorbitol at a wide range of concentration. Methods: Xylitol and sorbitol solubilized with simulated salivary buffer at a range of $0.8{\mu}M$ to 1.05 M were used. Candida albicans strains, ATCC strains 10231, 11006, and 18804 were used for the candidacidal assay. The candidacidal activities of xylitol and sorbitol were determined by comparing the numbers of colony forming units between in the presence and absence of xylitol or sorbitol and calculating the percent loss of cell viability. Results: There were some differences in the candidacidal activities according to the types of sugar alcohols and C. albicans strains. The candidacidal activity of more than 10% was observed when a final concentration of 32.9 mM in xylitol or sorbitol was maintained and that of about 20% was observed when a final concentration of 131 mM was maintained. Even at a high concentration of 1.05 M, the candidacidal activity of xylitol or sorbitol was about 20%. Conclusions: Xylitol and sorbitol at the concentrations used in commercial oral health care products had some levels of candidacidal activities.

• 대한의생명과학회지
• /
• 제4권2호
• /
• pp.103-112
• /
• 1998

과산화 효소와 포도당 산화효소의 효소반응을 이용하여 혈액 중 당을 측정하는 혈당 측정 용 스트립을 개발하였다. 멤브레인에 포도당 산화효소와 과산화 효소, 색원체를 건조처리하면 혈당이 멤브레인에 처리된 포도당 산화효소와 즉각 반응하여 과산화 수소를 발생하고 발생된 과산화 수소가 과산화 효소와 반응하여 착색물을 형성한다. 제조된 스트립은 혈액과 접촉하면 반응시간 2∼3분 이내에 0∼800mg/d1의 혈당에 대하여 농도에 따라 연 녹, 청 녹, 짙은 청색을 나타내며 이때 민감도는 40 mg/dl이었다. 육안용 혈당 스트립을 이용하여 정상을 포함한 당뇨 환자의 혈당 농도를 측정한 결과 Ames사와 BM사에서 시판하고 있는 제품과 유사한 결과를 얻을 수 있었다. 본 연구에서 개발된 스트립이 자동 분석기기의 재료로 활용될 수 있는지 여부를 알아보기 위하여 분광 비색계로 발색 반응의 최적 파장을 분석하고 최적 파장에서 각 혈당 농도별 반사 밀도를 측정하여 검정선을 얻었다. 이 검정선에 의해 임상 혈청시료의 혈당 농도를 측정한 결과 일본의 Kyoto Daiichi사의 혈액 분석시스템과 유사한 결과를 얻었다. 이로서 본 연구에서 개발한 혈당 스트립을 이용하여 혈액 중 혈당량을 육안으로 측정할 수 있음은 물론 자동 분석기기의 기본 시료로 이용될 수 있음을 확인할 수 있었다.

• 한국버섯학회지
• /
• 제1권1호
• /
• pp.1-8
• /
• 2003

한국의 버섯재배는 1960년대 초에 정부에서 농산물 수출과 농민의 소득을 증대시키기 위하여 양송이와 표고의 증산계획을 세워 시작하였다. 농촌진흥청 산림청 등 국가 연구기관에서는 유전적 소질이 우수한 품종의 육성, 양질의 종균보급, 고품질 버섯을 대량생산하는 기술을 개발하고 농민에게 재배기술을 교육하고 현지 지도를 하였으며, 재배시설비 등을 정책적으로 지원하였다. 재배방법이 개발되어 농가에서 대량으로 생산하기 시작한 버섯종류는 표고, 양송이, 느타리버섯, 팽이, 영지, 큰느타리버섯 등이다. 현재 버섯을 재배하는 농가는 약 2만호, 생 버섯의 총 생산량은 약 17만톤으로 느타리버섯이 가장 많고 다음이 팽이, 표고, 양송이 순으로 많다. 버섯의 총 농업생산액은 7,000억원을 넘으며, 연중생산이 가능한 농가의 중요한 소득작목으로 발전하였다.

• Fisheries and Aquatic Sciences
• /
• 제18권1호
• /
• pp.13-20
• /
• 2015

Calculated chemical scores (computed in relation to the FAO/WHO reference protein) for salmon liver protein hydrolysates indicated that all amino acids (other than methionine and threonine) were present in adequate or excess quantities; thus, the raw liver material is a good source of essential amino acids. The hydrophobic amino acids contents in hydrolysates prepared from Oncorhynchus keta and O. gorbuscha were 38.4 and 39.1%, respectively. The proportion of released peptides exceeding 500 kDa was reduced when hydrolysates were treated with the commercial enzyme Alcalase, although proportions in the following MW ranges were elevated: 100-500 kDa and <50 kDa. The optimal conditions for enzymatic hydrolysis were as follows: pH 7.0, $50^{\circ}C$, and a reaction time of 1 h. Of the different proteases tested, Alcalase was the most efficient for production of salmon liver hydrolysate with the highest 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging activity. The hydrolysates prepared from salmon liver had a balanced amino acid composition. The liver protein hydrolysates contained low molecular weight peptides, some of which may be bio-active; this bio-active potential should be investigated. Inhibition of the DPPH radical increased with increased degree of hydrolysis (DH), regardless of protease type. DPPH radical scavenging abilities, antithrombotic effects and ${\alpha}$-glucosidase enzyme inhibition effects of O. keta liver hydrolysate increased in a dose-dependent manner. Thus, salmon liver hydrolysate may be useful in functional food applications and as a source of novel products.

• 대한의생명과학회지
• /
• 제24권1호
• /
• pp.30-34
• /
• 2018

Silver (Ag) has been widely used in commercial products and medical fields since ancient times because of its antibacterial effect. It is harmless and non-toxic to the human body. For this reason, recent research has actively evaluated antimicrobial activity using silver (Ag). In this study, we investigated the inhibitory effect of a silver-based compound, silver phosphate ($Ag_3PO_4$) on the growth of Staphylococcus aureus and the activation of human immunity. First, the inhibitory effect of $Ag_3PO_4$ on the growth of Staphylococcus aureus was confirmed by a growth curve and a colonyounting method. As a result, the growth inhibitory effect increased as the concentration of $Ag_3PO_4$ increased. Specifically, treatment with $5{\mu}g/mL$ of $Ag_3PO_4$ resulted in no bacteria growth, and the colony-counting method showed a remarkable inhibition. In addition, the expression of cytokine IL-8 by $Ag_3PO_4$ was examined to investigate the cellular immune system activation by $Ag_3PO_4$. After pretreatment of Staphylococcus aureus for 1 hour with $50{\mu}g/mL$ $Ag_3PO_4$, an increased IL-8 mRNA expression resulted. In cells treated with $Ag_3PO_4$, we found that the expression of IL-8 was enhanced in a time-dependent fashion compared to non-treated cells. These results indicate that $Ag_3PO_4$ induces antimicrobial activity against Staphylococcus aureus and activates human immunity. These results are expected to contribute to the future study of the mechanism of silver (Ag) and silver-based compounds in relation to antibacterial activity.

• 한국의류산업학회지
• /
• 제18권4호
• /
• pp.412-423
• /
• 2016

This paper explores the possibility, and suggests an experimental procedure, of industrial application of traditional textile design techniques, such as hand silkprinting and natural dyeing. Theoretical and traditional background of this study is William Morris and his followers' Arts and Crafts Movement from the late 19th century to the early 20th century, which laid the philosophical as well as technical foundations of modern textile design tradition. Based on the basic understanding of the design philosophy, and starting from the design techniques of Morris and his successors, I made some experimental and systematic color plans reflecting and exploiting the physical traits and structure of jacquard woven silk material fabrics. And I applied hand silkscreen printing techniques on the jacquard silk fabrics of my own making, while testing various color combinations of natural dyes. After finishing final processing of design samples, I could get textile design products which met the criteria of my original expectation, i.e., eco-friendly and aesthetic design samples that can also be produced in automatized mass production system of contemporary textile industry. The conclusion of this experimental study is that I can expect the natural dyeing techniques, jacquard silk fabrics design techniques, silkprinting techniques, and the basic processes used in this study to be safely applied for contemporary commercial textile industry utilizing automatized silkscreen printing system and digital printing devices.

• 한국의류산업학회지
• /
• 제17권6호
• /
• pp.988-995
• /
• 2015

Gaps between the upper edges of brassiere mold cups and the breasts are one of the most serious issues in realizing comfort wearing of commercial brassieres for small-breasted women. The surplus ease amounts causing the fit problem were measured from 3D wearing images of the small-breasted women's brassieres. The effect after the removing the surplus ease amounts from the upper edge of mold cup was approved by subjective wearing evaluation. Since the volume distribution of mold cup can also affect the wearing sensation of brassiere, the subjective wearing sensation was compared for two brassieres of different volume distributions, V_L, of which volume was concentrated at the lower cup, and V_C, which has the thickest part at the nipple. As the results, the suitable sensation for cup volume and the natural wearing silhouette could be accomplished by removing the surplus ease amounts from the upper edge of mold cup to reduce the gaps between brassieres and the breasts, which could be accomplished through an approach reducing the volume near the upper edge of mold brassiere cup and making the volume concentrated at the lower cup. These works provide a useful information on the design of the brassiere mold cups for small-breasted women. Moreover, modeling methods of 3D scan data and 3D printing technique for making more accurate mold cases used in this research can be helpful to develop and evaluate clothing products in future.

• 대한토목학회논문집
• /
• 제33권4호
• /
• pp.1559-1569
• /
• 2013

본 연구는 지역적 범위에 따른 화물자동차의 통행발생 특성을 비교 분석함으로써 지역간 및 대도시 화물수요모형 추정의 차이점을 도출하고 지역적 범위에 적합한 화물수요모형 개발의 필요성을 제시하고자 하였다. 지역간 및 대도시 화물자동차의 통행발생 특성을 분석하기 위하여 화물자동차 속성, 출발지 특성, 도착지 특성, 적재품목을 고려한 서열로짓모형을 구축하였으며, 이를 통하여 다양한 특성이 화물자동차의 통행발생에 미치는 영향을 정량적으로 분석하였다. 분석결과, 지역간 화물자동차와 대도시 화물자동차의 통행발생 특성은 화물자동차 속성, 출발지 특성, 도착지 특성, 적재품목에서 모두 서로 상이한 것으로 나타났다. 특히 지역간 화물자동차는 대도시와 달리 출발지 및 도착지 유형이 제조업이고, 출발지 및 도착지의 산업단지 생산액이 클수록 통행수가 많은 것으로 나타났다.