• Asian-Australasian Journal of Animal Sciences
• /
• v.14 no.9
• /
• pp.1342-1351
• /
• 2001

Over the years, the embryo transfer industry has grown from the simple collection & transfer of embryos into an advanced field of embryo biotechnology. Currently a large demand exists for bovine oocytes and early embryos in both research and commercial settings. Bovine embryos can now be produced in-vitro. Primary oocytes collected from antral follicles of abattoir - obtained ovaries can be induced to undergo the maturation process. In-vitor maturation system, however must ensure that the resulting oocyte is capable of undergoing normal fertilization and yields a zygote competent of developing to term after embryo transfer. Sperm preparation for IVF has improved with the use of heparine. The use of co-culture system has proved beneficial in circumventing the developmental block in IVM/IVF bovine embryos.

• Proceedings of the KSME Conference
• /
• 2003.11a
• /
• pp.974-979
• /
• 2003

This study aimed to analyze spray characteristics and the ambient flow field in the mixture preparation state of the premixed combustion stage. It is very important to understand the spray characteristics and the fuel injection conditions in direct injection diesel engine because the emission gas compositions from diesel engines are related to spray formation processes of the premixed combustion stage. The numerical simulation was performed using the STAR-CD which is a commercial CFD code. Computed results of the transient high pressure diesel spray were compared with experimental results of the same spray injection condition in the constant volume chamber. The results show that spray patterns of numerical simulation agree with this experimental results comparatively.

• 한국정보디스플레이학회:학술대회논문집
• /
• 2002.08a
• /
• pp.788-791
• /
• 2002

The phosphors of high luminous efficiency for PDP application must have high purity, single phase, and dense surface. In this work, the polymeric reaction was applied to preparation of spherical phosphor by aerosol pyrolysis in order to enhance mechanical and optical characteristics. The red phosphor of (Y,Gd)$BO_3$:Eu was prepared from polymeric precursor, in which citric acid and ethylene glycol were used as ion carriers, i.e monomers. For enhancing the luminescence intensity and mechanical characteristics. optimum synthesizing condition were investigated through concentration of monomers, synthetic temperature. doped activator concentrations, and annealing process. The phosphors synthesized with monomers showed quite different morphology from those without monomers. It was observed that polymeric precursor made an effect on particle formation mechanism and status of particles surface. The resultant spherical phosphors show the comparable luminescent properties to the commercial product (product by Nichia co.). Also, they were observed to have the rigid surface.

• Journal of Powder Materials
• /
• v.22 no.4
• /
• pp.260-265
• /
• 2015

Spherical fine cobalt powders were fabricated by new liquid reduction method. Commercial cobalt sufate heptahydrate was used as raw material. Also ethylene glycol was used as solvent and hydrazine-sodium hypophosphite mixture was used as reduction agent for the new liquid reduction method. A plate shaped cobalt powders with an approximately 300 nm were prepared by a traditional wet ruduction method using distilled water as solvent and hydrazine. Spherical fine cobalt powders with an average size of $1-3{\mu}m$ were synthesized by a new liquid reduction method in 0.3M cobalt sulfate and 1.5M hydrazine-0.6M sodium hypophosphite mixture at 333K.

• Journal of Pharmaceutical Investigation
• /
• v.40 no.5
• /
• pp.297-304
• /
• 2010

The present work focuses on preparation of olanzapine, orally dispersing tablets by direct compression method. Effect of super disintegrant crospovidone, disintegration time, drug content on in vitro release has been studied. A factorial design was employed in formulating a prompt dispersible tablet. The selected independent variables crospovidone and fmelt showed significant effect on dependent variables i.e. disintegration time and percent drug dissolved. Disintegration time and percent drug dissolved decreased with increase in the level of crospovidone. The similarity factor $f_2$ was found to be 97.48 for the developed formulation indicating the release was similar to that of the marketed formulation. Pharmacokinetics of olanzapine after single-dose oral administration of orally disintegrating tablet in normal volunteers were evaluated and the results showed that PK parameters (Cmax, Tmax, AUC) of the designed ODT matrix were similar to those of commercial product, Zyprexa Zydis$^{(R)}$ as a reference.

• Biomolecules & Therapeutics
• /
• v.16 no.1
• /
• pp.28-33
• /
• 2008

Atorvastatin calcium salt (1) was obtained through the preparation of lactone compound (8) from 2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-ethyl)-2-phenyl-1,3,2-dioxaborinan-4-yl)acetic acid tert-butyl ester (9) by hydrolysis in basic condition. Efficient hydrolysis of boronate compound 9 aimed at the viable synthesis for commercial production and purification of Atorvastatin calcium is reported. Detail studies of evaluation procedure are also reported.

• Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
• /
• 1999.11b
• /
• pp.84-89
• /
• 1999

Treatment with the enzyme pectinase has been reported to lower the cationic demand of thermomechanical pulp(TMP) bleached with alkaline peroxide in the laboratory. We have extended this discovery to bleached TMP produced industrially, and shown that commercial enzyme preparations can treat pulp within 15 minutes at the at the temperature and pH values prevalent in paper mills. About half of the cationic demand in the bleached pulp can be destroyed by pectinase. Dynamic drainage jar experiments show that the enzyme treatment improves the effectiveness of several cationic polymers to increase retention in the absence of retention aids or with non-ionic polymers, and does not damage the strength properties of the pulp. Pectinase could be easily incorporated into paper machine stock preparation systems to lower the charges of cationic retention aids needed in furnishes containing peroxide-bleached mechanical pulp.

• Journal of Powder Materials
• /
• v.6 no.2
• /
• pp.139-144
• /
• 1999

The pure Ti, Ni and carbon powders were reaction milled to synthesize the TiC-Ni based cermet powders with ultrafine microstructures. After milling, the ultrafine TiC or amorphous Ti-Ni phase was obtained, respectively, according to the milling condition. The effects of milling variables on the synthesizing behavior of the powders were investigated in detail. The sintered TiC-Ni based cermet of the reaction milled powders consisted of very fine TiC of 0.2~1.5$\mu$m, as compared with that of a commercial cermet of 3~5$\mu$m. This demonstrates the potenial of reaction milling as an effective processing route for the preparation of cermet materials.

• Journal of Embryo Transfer
• /
• v.6 no.2
• /
• pp.18-29
• /
• 1991

Nuclear transplantation technique is known as the most potential and efficient method for producing a large number of genetically identical animals from a single embryo. The technical development of nuclear transplantation in mammals and its application to the production of cloned animals are described. For the efficient and successful production of cloned embryos by nuclear transplantation, the right selection and micromanipulation of recipient eggs or embryos as capacious recipient cytoplasm, the adequate and benefitlal preparation of multiple totipotent embryonic cells as donor nuclei, and also the fusion technique are very critical. Recent studies approaching to these critical points are introduced and discussed. Up to date, the overall efficiency of production of cloned embryos and offspring in livestock is estimated to be low. Further technical development of nuclear transplantation will enable large-scale production of cloned livestock and in near future the commercial cloning of animals will become a reality.

• The Korean Journal of Food And Nutrition
• /
• v.10 no.1
• /
• pp.122-126
• /
• 1997

Bifidobacteria have been known as beneficial inhabitant of human intestine. Therefore, bifidobacteria began to be noticed as a starter in the manufacture of fermented dairy products. Perhaps the key for effective use of bifidobacteria in commercial dairy products is the maintenance of viability of bifidobacteria during large scale preparation of starter culture and distribution of products. So we tried to obtain the bifidobacteria having suitable characteristics for using as a starter in the manufacture of fermented dairy products. Among bifidobacteria isolated from Korean, E-4 strain showed the highest resistance to oxygen. To know whether the selected strain will be fit for manufacture of fermented dairy products, we also investigated resistance of the selected strain to HCI. The selected strain, E-4, was more resistant to environmental stresses such as oxygen, H2O2 and HCI than Bifidobacterium longum known as resistant strain to environmental stresses. According to carbohydrate fermentation patterns and morphological characteristics, E-4 strain was identified as B. bifidum. In conclusion, the selected strain, E-4, was thought to be fit for manufacture of fermented dairy products.