• CELLMED
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• v.2 no.2
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• pp.18.1-18.16
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• 2012

An oncology-specific database called OncoRx (http://bit.ly/cancerRx) was previously set up in cyberspace to aid clinicians in identifying interactions of anticancer drugs (ACDs) and chemotherapy regimens with traditional Chinese medicines (TCMs) and complementary and alternative medicines (CAMs). Since then, users have requested the drug-CAM interactions (DCIs) of 5 specific CAMs (cranberry, melatonin, co-enzyme Q10, huachansu, reishi mushroom) to be updated in the database. Pharmacokinetic properties (metabolism, enzyme induction/inhibition, elimination), TCM properties and DCIs of each CAM were collated with 117 ACDs using 9 hardcopy compendia and online databases as resources. Additionally, individual ACDs and CAMs were used as keywords for PubMed searches in combination with the terms 'anticancer drugs', 'drug interactions', 'herb-drug/drug-herb interactions', 'pharmacokinetic interactions' and 'pharmacodynamic interactions'. DCI parameters consisted of interaction effects, evidence summaries, proposed management plans and alternative non-interacting CAMs, together with relevant citations and update dates of the DCIs. OncoRx is also used as a case to introduce the "Four Pharmaco-cybernetic Maxims" of quality, quantity, relationship and manner to developers of digital healthcare tools. Its role in Hayne's "5S" hierarchy of research evidence is also presented. OncoRx is meant to complement existing DCI resources for clinicians and alternative medicine practitioners as an additional drug information resource that provides evidence-based DCI information for ACD-CAM interactions.

• Korean Journal of Artificial Intelligence
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• v.9 no.2
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• pp.23-28
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• 2021

In this paper, we studied a system that can efficiently build security management for single-person households using Arduino, ESP32-CAM and PIR sensors, and proposed an Android app with an internet connection. The ESP32-CAM is an Arduino compatible board that supports both Wi-Fi, Bluetooth, and cameras using an ESP32-based processor. The PCB on-board antenna may be used independently, and the sensitivity may be expanded by separately connecting the external antenna. This system has implemented an Arduino-based Unauthorized intrusion system that can significantly help prevent crimes in single-person households using the combination of PIR sensors, Arduino devices, and smartphones. unauthorized intrusion system, showing the connection between Arduino Uno and ESP32-CAM and with smartphone applications. Recently, if daily quarantine is underway around us and it is necessary to verify the identity of visitors, it is expected that it will help maintain a safety net if this system is applied for the purpose of facial recognition and restricting some access. This technology is widely used to verify that the characters in the two images entered into the system are the same or to determine who the characters in the images are most similar to among those previously stored in the internal database. There is an advantage that it may be implemented in a low-power, low-cost environment through image recognition, comparison, feature point extraction, and comparison.

• International Journal of CAD/CAM
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• v.3 no.1_2
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• pp.13-17
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• 2003

Hybrid method of representing geometric entities as combination of boundary (B-rep) and functional (F-rep) representations is presented which can be used as a basis of solid modeling kernel. It contains whole functionality of classic B-rep kernel, and also supports enveloping (sweep of solid body). Principles and keysolutions are considered. Example of a real task that comes from gearing is provided.

• Journal of Advanced Information Technology and Convergence
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• v.10 no.2
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• pp.167-175
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• 2020

In this paper, we propose a traffic accident detection on vehicle-mounted camera. In the proposed method, the minimum bounding box coordinates the central coordinates on the bird's eye view and motion vectors of each vehicle object, and ego-motions of the vehicle equipped with dash-cam are extracted from the dash-cam video. By using extracted 4 kinds features as the input of Bi-LSTM (bidirectional LSTM), the accident probability (score) is predicted. To investigate the effect of each input feature on the probability of an accident, we analyze the performance of the detection the case of using a single feature input and the case of using a combination of features as input, respectively. And in these two cases, different detection models are defined and used. Bi-LSTM is used as a cascade, especially when a combination of the features is used as input. The proposed method shows 76.1% precision and 75.6% recall, which is superior to our previous work.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2007.05a
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• pp.285-288
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• 2007

The use of commercial finite element analysis software to perform the entire process analysis and springback analysis has increased fast for last decade. Pamstamp2G is one of commercial software to be used widely in the world but it has still not been perfected in the springback prediction accuracy. We must select the combination of input parameters for the highest springback prediction accuracy in Pamstamp2G because springback prediction accuracy is sensitive to input parameters. Then we study the affect of input parameters to use member part for acquiring high springback prediction accuracy in Pamstamp2G. First, we choose important four parameters which are adaptive mesh level at drawing stage and cam flange stage, Gauss integration point number through the thickness and cam offset on basis of experiment. Second, we make a orthogonal array table L82[(7)] which is consist of 8 cases to be combined 4 input parameters, compare to tryout result and select main factors after analyzing affect factors of input parameters by Taguchi's method in 6 sigma. Third, we simulate after changing more detail the conditions of parameters to have big affect. At last, we find the best combination of input parameters for the highest springback prediction accuracy in Pamstamp2G. The results of the study provide the selection of input parameters to Pamstamp2G users who want to Increase the springback prediction accuracy.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.3
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• pp.1299-1308
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• 2016

Our previous studies clearly demonstrated that a combination of WP 631 and Epo B has higher activity against ovarian cancer cells than either of these compounds used separately. In order to fully understand the exact mechanism of action in combination, we assessed effects on the cell cycle of SKOV-3 cells. We evaluated three control points essential for WP 631 and Epo B action to determine which cell cycle-regulating proteins (CDK1/cyclin B complex, EpCAM or HMGB1) mediate activity. The effects of the drug on the cell cycle were measured based on the nuclear DNA content using flow cytometry. Expression of cell cycle-regulating genes was analyzed using real-time PCR. It was discovered that WP 631, at the tested concentration, did not affect the SKOV-3 cell cycle. Epo B caused significant G2/M arrest, whereas the drug combination induced stronger apoptosis and lower mitotic arrest than Epo B alone. This is very important information from the point of view of the fight against cancer, as, while mitotic arrest in Epo B-treated cells could be overcame after DNA damage repair, apoptosis which occurs after mitotic slippage in combination-treated cells is irreversible. It clearly explains the higher activity of the drug combination in comparison to Epo B alone. Epo B acts via the CDK1/cyclin B complex and has the ability to inhibit CDK1, which may be a promising strategy for ovarian cancer treatment in the future. The drug combination diminishes EpCAM and HMGB1 expression to a greater degree than either WP 631 and Epo B alone. Owing to the fact that the high expression of these two proteins is a poor prognostic factor for ovarian cancer, a decrease in their expression, observed in our studies, may result in improved efficacy of cancer therapy. The presented findings show that the combination of WP 631 and Epo B is a better therapeutic option than either of these drugs alone.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.4 no.3
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• pp.121-125
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• 2003

A switch box is metal box for electric wire pipes in building. In manufacturing this box, the first press is used to mold and the second to fifth presses are used to process four-sides of a box. So four presses, four molds and four workers are needed. This leads to raise the manufacturing cost including machine lease rent, molding fee, and wages. To make matters worse, the roaring sound, vibration, and dangers of safety accidents make employees avoid from working that job. To solve this problem, a new Handling Mechanism and a cam die which combined four-die-involving processes into one die process were developed. That results job automation of the Job with one press and one die. The job avoidance problem is solved and manufacturing cost is reduced as well.

• Journal of Digital Convergence
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• v.18 no.8
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• pp.427-433
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• 2020

Based on the natural colors and techniques of Korean traditional Dancheong, the image from splendor and magnificence is used as a jewel in making ornaments by subjective interpretation of the researcher. The purpose of this paper is to propose the possibility of using as a jewelry design by combining the possibilities of various color expressions, the combination of solidity and luster synthetic resin by utilizing natural pigments and mono images used in Korean traditional monophonic. In this study, this study presented the possibility of accessing in the life of a modern person pursuing a lifestyle by introducing a mono image into jewelry design, and at the same time, approaching ornaments by using traditional materials of the past, modern materials, and digital production methods. We are looking for a wide variety of jewelry designs to be utilized.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.38C no.9
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• pp.781-786
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• 2013

Multiplexing information over parallel data channels based on RF MIMO concept is possible to achieve considerable data rates over large transmission ranges with just a single transmitting element. Visual multiplexing MIMO techniques will send independent streams of bits using the multiple elements of the light transmitter array and recording over a group of camera pixels can further enhance the data rates. The proposed system is a combination of the reliance on computer vision algorithms for tracking and OOK cell frame modulation. LED array are controlled to transmit message in the form of digital information using ON-OFF signaling with ON-OFF pulses (ON = bit 1, OFF = bit 0). A camera captures image frames of the array which are then individually processed and sequentially decoded to retrieve data. To demodulated data transmission, a motion tracking algorithm is implemented in OpenCV (Open source Computer Vision library) to classify the transmission pattern. One of the most advantages of proposed architecture is Computer Vision (CV) based image analysis techniques which can be used to spatially separate signals and remove interferences from ambient light. It will be the future challenges and opportunities for mobile communication networking research.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.2
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• pp.532-539
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• 2010

This paper suggests the system for searching and application is to be in combination between existing hair art area and Image/Video processing area. This proposed system usually saves various hair types into a database, then, users send images of their face over the internet by using WebCam. Finally, they can find the hair types for users.