• 한국의학물리학회지:의학물리
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• 제18권2호
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• pp.98-106
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• 2007

2005년 6월 연세의료원 세브란스병원에서는 진단목적으로 20대의 5 mesa 화소 Totoku ME511L 평판 LCD 표시장치를 추가하여 PACS를 확장하였다. 20대의 Totoku ME511L 표시장치를 대상으로 반사, 휘도 반응, 휘도 공간 의존, 분해능, 잡음, 베일링 그레어, 그리고 색도 항목에 대하여 AAPM TG 18보고서에 기준하여 정량적인(또는 시각적인) 인수검사를 실시하였다. 측정에 사용된 장치는 색도를 측정할 수 있는 만원경식 휘도계, 조도계, 반사 측정에 필요한 빛 선원, 빛 차단 장치, 그리고 TG18 테스트 패턴들이었다. 선택된 8대의 표시장치에 대한 평균 확산 반사계수($R_d$)는 $0.019{\pm}0.02sr^{-1}$이었다. 휘도 반응 검사에서, 휘도비(LR), 최대 휘도 변이($L_{max}$), 그리고 최대 대조도 반응 변이는 각각 $550{\pm}100,\;2.0{\pm}1.9%$, 그리고 $5.8{\pm}1.8%$이었다. 휘도 균일도 검사에서, 최대 휘도 변이는 TG18-UNL10 테스트 패턴의 10% 휘도에 대하여 $14.3{\pm}5.5%$이었다. 분해능 측정은 휘도 측정법으로 수행하였으며 중심에서 퍼센트 휘도(${\Dalta}L$)는 $0.94{\pm}0.64%$이었다. 시각적인 방법의 잡음측정의 모든 경우에서, 중앙 및 주위 4사분면에서 가장 작은 것을 제외하고 15개의 모든 정사각형의 표적을 인식할 수 있었다. 글레어 비(GR)은 $12,346{\pm}1,995$이었다. 최대 색도 균일도 지표(D)는 $0.0025{\pm}0.0008$이었다. 또한 국내 실정에 적합한 진단용 표시장치의 정도관리 가이드라인 연구 결과를 제시하였다. 모든 인수검사 결과는 AAPM TG18 보고서 기준에 포함되어 진단 목적으로 사용하기에 적합하였다. 결론으로 인수검사는 표시장치가 진단에 사용하기에 적합한 성능임을 알려줄 뿐만 아니라 정도관리의 가이드라인, 최적 판독 환경, 그리고 표시장치의 교체시기를 결정하여주는 중요한 역할을 할 수 있다.

• 한국농림기상학회지
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• 제11권4호
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• pp.162-173
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• 2009

기후변화에 따른 작물 재배적지의 이동에 관한 정보는 농업분야 적응전략의 기초이기 때문에 연구자들뿐 아니라 정책결정자들도 큰 관심을 보인다. 하지만 재배적지의 개념을 분석차원에서 구체적으로 구현하는 일이 어렵기 때문에 아직 실용적인 적지판정법이 개발된 적이 없다. 본 연구에서는 미래 시나리오 기후조건에서 사과 '후지'의 재배적지를 조사하기 위해 GIS 기반의 탐색기법을 이용하여 전자기후도, 토양전자지도, 수치지형정보, 농업기후 및 작물품질 예측모형 등을 종합적으로 활용, 체계적인 적지판정기법을 구현하였다. '후지'를 대상으로 한 적지판정 1차기준은 지표피복, 경사도, 토성이며, 2차 기준은 월동기간 중 동해위험도, 늦서리 피해위험도, 생육가능기간 등 기후조건, 3차기준은 과피의 색택, 과형지수 등 품질조건이다. 이들 조건을 지리정보시스템의 속성 레이어로 구현하고 중첩분석을 통해 재배적지를 검색하였다. 이 방법을 현재평년(1971-2000년)과 A1B 시나리오의 미래평년(2011-2040년, 2041-2070년, 2071-2100년) 기후에 적용하여 남한 전역을 대상으로 재배적지를 검색한 결과 현재평년의 경우 전국의 6.5%가 후지 재배적지에 해당하였고 2011-2040년 평년기후에는 전국의 약 1.8%, 2041-2070년 평년에는 0.3%, 2071-2100년 평년에는 전국의 0.1%까지 감소하여 전국규모에서 재배적지의 한계선 북상추세를 감지할 수 있었다. 뿐만 아니라 개별 주산지 내에서도 적지이동 양상을 정밀하게 추적할 수 있음을 확인하였다.

• 헤리티지:역사와 과학
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• 제53권2호
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• pp.254-269
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• 2020

본 연구는 '고도 이미지 찾기 사업' 중 가로경관개선 사업의 하나인 담장에 대한 이론과 담장 디자인 선행 연구를 통하여 고도에서의 담장에 어울리는 담장 정비 방향을 제언하고자 한다. 연구방법은 선행 연구를 유목화하고, 담장 디자인 이론을 고찰한 후, 고도 지정 지구의 의의와 '고도 이미지 찾기 사업'의 현황을 분석하였다. 이를 바탕으로 사례 대상지를 선정하여 고도담장정비 사례 현황과 문제점을 파악하고 개선 방안을 여러 특성을 비교하여 분석하였다. 담장의 선행 연구는 담장의 성격 분석, 담장 디자인 원리 응용, 담장 구조·색채와 형태 및 응용, 현대적 재해석, 궁궐 담장, 주택·사찰·마을의 담장 등 6개 항목으로 유목화되었다. 담장은 '고도 이미지 찾기 사업' 중 가로경관개선 사업에 해당하며 시지각적 인지도가 내부 건축물보다 선경험으로 제공되는 특성이 있다. 고도담장정비 사례 대상지는 고도별 특별보존지구와 보존육성지구의 구성 분포 비율을 기준으로 무령왕릉과 인접한 공주시 송산리길 주변 마을을 선정하였다. 공주시 송산리길 주변 마을의 '고도 이미지 찾기 사업'은 한옥 신축으로 시작되었다. 그러나 담장 정비는 한옥 신축과 동시에 시행된 게 아니었다. 가로변 건축물 외관 정비 사업으로 추후에 지원과 정비가 이루어진 것이다. 한옥과 담장이 동시에 설계되어 심의 후 신축되었다면 한옥의 규모 및 디자인과 조화를 이루는 담장이 되었을 것이지만 서로 기간을 두고 신청, 설계, 시공되었기에 한옥의 처마와 담장이 대지 경계선에 거의 맞닿아 있는 결과를 초래하였다. 공간적으로 가깝고 높은 한옥 본채와 담장의 배치는 답답하게 닫혀 있는 구조물로 인식된다. 송산리길의 담장 디자인은 고도의 특성을 나타낼 수 있는 형태와 색상과 재료로 차분하고 은은하며 안온한 분위기를 자아내야 하는데, 날카롭고 옹색하여 난처한 지경에 놓여 있다. 이러한 문제점을 개선하려면 담장 설계 디자인을 먼저 고려한 후, 한옥 본채 설계 디자인을 후순위로 진행하는 방안의 도입도 합리적 대안이 될 수 있다. 사례 대상지인 공주시 송산리길 담장 지원 사업의 문제 요인은 전통 담장이 가져야 할 미적 요건에 상당히 부족하다. 첫째, 담장의 자연 재료 선정 및 활용에서 미적 의식이 실종되었다는 것이다. 둘째, 디자인 완성도와 조화의 부재이다. 조사 대상지인 공주시 송산리길 고도담장정비의 문제 요인을 분석한 개선 방향은 다음과 같다. 첫째, 한옥 설계와 담장·대문 시공 설계 도면을 함께 심의해야 한다. 둘째, 한옥 담장 디자인의 자연석 돌담 일변도를 재검토 진단하여야 한다. 셋째, 계획·설계 과정에 주민과 전문가의 의견을 조정하는 상시 체계를 가동해야 한다. 넷째, 한옥의 개별성을 집단화하여 지역의 정체성을 대표하는 문화 자산으로 가치를 높여야 한다.

• 암석학회지
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• 제15권3호
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• pp.154-166
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• 2006

이 연구에서는 국내에서 가행되고 있거나 종료된 것으로 파악된 약 600여개소의 석재석산을 대상으로 지리적인 분포 유형 특성을 파악하는데 목적을 두었다. 국내의 석재석산은 전국적으로 비교적 고르게 분포하고 있으나 분포 유형의 구분은 가능하다. 석재석산이 가장 집중되어 분포하는 지역은 원주-제천-문경-거창-진안-남원-거금도로 이어지는 북북동 방향의 지역으로 국내 석재석산의 약 50%의 점유율을 보이며, 우리나라의 주요 석재벨트를 이루고 있다. 그 다음으로는 강경-익산-김제 벨트, 경기도의 포천-의정부 일대, 충청남도의 보령일대가 주 석재채석산지로 알려져 있다. 국내에서 채석되었던 석재의 암종은 사암, 대리암, 슬레이트, 편암, 편마암, 응회암, 현무암, 안산암, 유문암, 규장암, 각섬암, 반려암. 섬록암, 섬장암, 화강암의 15개 암종에 국한된다. 그러나 이들 중 현재는 화강암, 섬록암, 대리암 등의 $7{\sim}8$개 암종의 석재만이 생산되고 있으며 나머지 암종의 생산실적은 거의 없는 편이다. 국내에서 채석되었던 석재석산을 대표암종별로 분류하여 보면 심성암류가 87%, 퇴적암류 6%, 변성암류 4%, 화산암류 3%이며 심성암류에서는 화강암과 섬록암, 퇴적암류에서는 사암, 변성암류에서는 대리암이 주요 채석대상 암종이다. 도별 점유율을 보더라도 모든 도에 분포하는 석재자원의 $80{\sim}90%$는 심성암류이며, 예외적으로 지질학적 특수성으로 인하여 제주도는 화산암인 현무암 석재만이 개발되었다. 석재 암종별 분포를 보면 화강암 석재가 전국적으로 가장 많이 분포하나 전남지역은 타도와는 달리 섬륵암 석재 자원이 풍부한 것으로 조사되었다. 또한 강원도와 충청북도는 대리석 석재자원이 타도에 비해 비교적 우세하게 분포하고 있으며, 충청남도는 사암(오석) 석재자원이 생산되는 유일한 지역으로 조사되었다 이러한 도마다의 석재의 품종이 다른 것은 그 지역의 지질학적 암층발달의 특성에 따른다. 국내 석재의 입도 분포를 보면 600여개의 석산 중 중립질 내지 조립질의 입도를 보이는 석산이 50%이상을 점하고 있으며, 거의 모두 화강암 석재이다. 그 다음으로는 세립질 화강암 석재로 약 10% 내외의 점유율을 나타낸다.

• 대한원격탐사학회지
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• 제38권5_1호
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• pp.609-625
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• 2022

위성산출물의 검증은 위성자료를 이용하게 되는 후속 분석작업에 결정적인 영향을 미친다. 특히, 탁하고 얕은 수심의 육상 인근 해역에서의 해색산출물은 해수구성입자 분포의 복잡성으로 인하여 오랫동안 그 성능 개선이 이루어지지 않고 있어왔다. 또한, 선박이나 고정관측소를 이용한 검증은 위성산출물과 현저히 차이나는 공간범위로 인하여 명확한 한계점을 노출해왔었다. 본 연구는 우선 선박을 이용한 현장조사를 통해서 천리안해양위성2호(GOCI-II)의 주요 산출물인 원격탐사반사도, 엽록소농도, 총부유물농도, 용존유기물 등에 대한 검증을 수행하였다. 둘째로, 본 연구에서는 드론영상을 이용한 산출물 검증을 위한 초기분석결과를 제시하였다. 선박과 위성사이의 공간범위 차이를 메우기 위하여 각 선박 정점에서 드론에 탑재된 MicaSense RedEdge 카메라를 이용해 해수에 대한 다분광 영상을 획득하였다. 향후 드론을 이용한 위성산출물 검증에 활용되도록 드론 고도에 따른 해수복사휘도의 변화를 분석하였다. 제한된 숫자의 현장조사 자료 개수이지만, 검증결과, 555 nm 에서의 GOCI-II 원격탐사반사도는 약 30% 가량 과대추정 되는 것으로 나타났고, 엽록소농도 및 용존 유기물은 현장 측정값과의 상관도가 낮았다. 총부유물농도는 결정계수 약 0.6의 상관도를 나타내었고 약 20%의 불확도를 가지는 것으로 나타났다.

• 대한원격탐사학회지
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• 제39권6_1호
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• pp.1211-1224
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• 2023

구름은 광학위성을 이용한 국토 관측 및 재난 대응, 변화 탐지 등 지표의 현상을 관측하는데 있어 많은 어려운 문제를 야기한다. 구름의 존재는 영상 처리 단계 뿐만 아니라 최종적으로는 데이터의 품질에 영향을 미치므로 이를 반드시 식별하고 제거하는 과정이 필요하다. 따라서 본 연구에서는 위성영상 내 구름의 분광패턴에 가장 근접한 화소를 탐색 및 추출해 최적의 임계값을 선정하고 임계값을 바탕으로 구름 산출물을 제작하는 일련의 과정을 자동으로 수행하는 새로운 구름 탐지 기법을 개발하고자 하였다. 구름 탐지 기법은 크게 세 단계로 구성된다. 첫 번째 단계에서는 Digital Number (DN) 단위 영상을 대기상층 반사율 단위로 변환하는 과정을 수행한다. 두 번째 단계에서는 대기상층 반사율 영상을 이용하여 Hue-Value-Saturation (HSV) 변환 및 삼각형 임계 처리, 최대우도 분류 등의 전처리를 적용하고 각 영상별로 초기 구름 마스크 생성을 위한 임계값을 결정한다. 세번째 후처리 단계에서는 생성된 초기 구름 마스크에 포함된 노이즈를 제거하고 구름 경계 및 내부를 개선한다. 구름 탐지를 위한 실험 자료로 구름의 공간적, 계절적 분포의 다양성을 보여주는 4~11월 시기에 한반도 지역에서 촬영된 국토위성 L2G 영상을 사용하였다. 제안 방법의 성능을 검증하기 위해 단일 임계화 방법으로 생성된 결과를 비교하였다. 실험 결과, 제안 방법은 기존 방법과 비교하여 전처리 과정을 통해 각 영상의 방사학적 특성을 고려할 수 있어 보다 정확하게 구름을 검출할 수 있었다. 또한, 구름 개체를 제외한 나머지 밝은 물체(판넬식 지붕, 콘크리트 도로, 모래 등)의 영향을 최소화하는 결과를 보여주었다. 제안 방법은 기존 방법 대비 F1-score 기준으로 30% 이상의 개선된 결과를 보여주었으나 눈이 포함된 특정 영상에서 한계점이 있었다.

• 대한원격탐사학회지
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• 제39권6_2호
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• pp.1635-1650
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• 2023

지구온난화로 인한 해수면온도 상승은 해양 생태계와 해양 생물에 열적 스트레스를 유발하여 해양 종의 생산성과 분포에 심각한 영향을 미친다. 이와 관련하여 최근 우리나라의 수산자원 중 살오징어의 어획량이 지속적으로 감소하고 있다. 본 연구에서는 지속적인 수산자원 관리를 위하여 어장 형성에 영향을 주는 해양환경을 분석하고 천리안해양관측위성 자료를 비롯한 여러 위성자료들을 이용하여 계절별 살오징어 서식지적합 모델을 개발하였다. 해수면온도는 14.11-26.16℃, 해수면높이는 0.56-0.82 m, 엽록소-a 농도는 0.31-1.52 mg m^-3, 일차생산량은 580.96-1574.13 mg C m^-2 day^-1인 범위에서 평균적으로 약 83%의 살오징어가 어획되는 것을 확인하였다. 계절별로 적합지수를 곡선 접합한 후, 네 가지 통계 방법으로 서식지적합지수를 개발하였고 그 중 산술평균을 사용한 모델이 가장 좋은 성능을 보였다. 개발한 통계 모델과 2019년 어획량 자료와 비교하였을 때, 계절별로 다른 해역에 생성되는 어장과 어획량이 높은 곳에 서식지적합지수가 높게 나타나는 것을 확인하여 모델이 잘 개발될 것을 볼 수 있었다. 또한, 살오징어의 어장 형성과 관련이 높은 해수면온도의 뚜렷한 증가 추세를 확인하였으며 앞으로 지속될 해양 온난화에 의해 어장이 변화할 것으로 예상이 된다. 수산자원 관리를 위해서는 꾸준히 모니터링하는 것이 필요하다고 보여진다.

• 한국전통조경학회지
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• 제41권4호
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• pp.21-29
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• 2023

문화예술의 전성기였던 북송시기는 중국 원림사에서 큰 변화를 가져 온 시기이다. 이전 당대(唐代)에 발전하였던 은둔과 사념(思念)들이 문학과 회화 그리고 예술과 결합되며 원림은 예술작품으로 인식되는 경향을 보이고 있다. 특히 북송시기 문학과 예술을 관통한 소식의 등장은 개인적 정원조성을 뛰어넘어 공공원림의 발전과 원림의 다변화에 영향을 주고 그의 오랜 폄적기간들은 지역문화와 특색을 이해하고 원림에 반영하는 계기가 되었다. 이에 본 연구는 다양한 원림을 경영하였던 소식의 사상에 주목하여 그의 폄적생활과 사상의 관계성을 통해 문인으로서의 그의 원림 경영을 살펴보았다. 이를 위해 소식이 경영한 현존하는 혜주의 백학거 원림을 중심으로 소식이 경영한 문인원림의 양태를 살펴본 결과 다음과 같은 특징과 가치를 표출하였다. 첫째, 유불도 삼가(三家)에 능통했던 소식은 백학거의 입지와 원림 구성요소에 사상과 독특한 조망 기법을 결합하여 경관을 즐기고 있다. 고택은 소박한 형태이나 내경과 외경의 결합을 통해 확장성을 지니고 있고 내경은 단일공간으로 인식되도록 구성하되 공간의 중첩적 경험과 다경관의 동시적 감상이 가능하도록 계획되어 있다. 반면 공간에는 반드시 위계를 설정하여 질서를 두고 있다. 둘째, 원림은 지역의 특징을 반영하여 아열대성 식물이 다수 나타나고 있고 건조물과의 색채적 대비를 고려하여 활색생향(活色生香)적 식재 형태가 나타나고 있다. 또한 시의적 정신세계를 원림에 투영하여 심신수양과 이상세계의 탐구적 장소로 원림을 차용하였고 거욕과 수심적 마음수행을 위한 장소로서 식재는 간결하되 특징을 잘 내보일 수 있는 수종을 선별 식재하여 원림 공간에 율동감과 입체감을 주고 있다. 셋째, 백학거는 시대별 변화를 보이고 있으나 근본적으로 후손들에 의해 소식이 조영한 원림의 양태와 원림 요소들이 현존하여 유산적 가치를 확인할 수 있다.

• 대한의용생체공학회:의공학회지
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• 제6권2호
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• pp.1-8
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• 1985

The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70$\pm$1.32mmHg/min)compared to CF dialyzers(4.32$\pm$0.55mmHg/min)(p<0.05). However, there was no observable difference in the UFR between the two dialyzers. Neither APD nor UFR showed any significant increase with an increasing number of reuses for up to more than 20reuses. A substantial number of failures observed in APD(larger than 20mmHe/min)on the reused dialyzers(2 out of 40 CP and S out 26 C-DAK) were attributed to the Possible damage on the fibers. The CF 15-11 HFDs which failed APD test did not show changes in the UFR compared to normal dialyzers indicating that APD is a more sensitive test than UFR test to evaluate the integrity of the fibers. 30527 T00401030527 ^x For quantitative measurement of reflected light from a clinical diagnostic strip, a prototype old reflectance photometer was designed. The strip loader and cassette were made to obtain more accurate reflectance parameters. The strip was illuminated at 45˚c through optical fiber and the intensity of reflected light was determined at rectanguLat angle using a photodiode. The kubelka-munk coefficient and reflection optical density were determined ar four different wavelengths(500, 550, 570 and 610nm) for blood glucose strip. For higher concentration than 300mg/41 about glucose, a saturation state of abforbance was observed at 500, 550 and 570nm. The correlation between glucose concentration and parameters was the best at 610nm. 30535 T00401030535 ^x Radiation-induced fibrosarcoma tumors were grown on the flanks of C3H mice. The mice were divided into two groups. One group was injected with Photofrin II, intravenously (2.5mg/kg body weight). The other group received no Photofrin II. Mice from both groups were irradialed for approximately 15 minutes at 100, 300, or 500 mW/cm2 with the argon (488nm/514.5 nm), dye(628nm) and gold vapor (pulsed 628 nm) laser light. A photosensitizer behaved as an added absorber. Under our experimental conditions, the presence of Photolfrin II increased surface temperature by at least 40% and the temperature rise due to 300 mW/cm2 irradiation exceeded values for hyperthermia. Light and temperature distributions with depth were estimated by a computer model. The model demonstrated the influence of wavelength on the thermal process and proved to be a valuable tool to investigate internal temperature rise. 30536 T00401030536 ^x We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs 3nd others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized tomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh IIci computer.The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal flare index are greater by the amount of approximately 8˚ and 0.5, respectively, (2) the shape of the isthmus cross section is more round, and (3) the distance between the teaser trochanter and the proximal border of the isthmus is shelter by about 15 mm. The results suggested that the femoral component suitable for Asians should be different from the currently-used components designed and manufactured mostly by European or American companies. 30537 T00401030537 ^x It is well known that nonlinear propagation characteristics of the wave in the tissue may give very useful information for the medical diagnoisis. In this paper, a new method to detect nonlinear propagation characteristics of the internal vibration in the tissue for the low frequency mechanical vibration by using bispectral analysis is proposed. In the method, low frequency vibration of f0( = 100Hz) is applied on the surface of the object, and the waveform of the internal vibration x (t) is measured from Doppler frequency modulation of silmultaneously transmitted probing ultrasonic waves. Then, the bispectra of the signal x (t) at the frequencies (f0, f0) and (f0, 2f0) are calculated to estimate the nonlinear propagation characteristics as their magnitude ratio, w here since bispectrum is free from the gaussian additive noise we can get the value with high S/N. Basic experimental system is constructed by using 3.0 MHz probing ultrasonic waves and the several experiments are carried out for some phantoms. Results show the superiority of the proposed method to the conventional method using power spectrum and also its usefulness for the tissue characterization. 30541 T00401030541 ^x This paper describes the implementation of a computerized radial pulse diagnosis by aids of a clinical expert. On this base, we composed of the radial pulse diagnosis system in korean traditional medicine. The system composed of a radial pulse wave detection system and a radial pulse diagnosis system. With a detection system, we detected Inyoung and Cheongu radial pulse wave and processed it. Then, we have got the characteristic parameters of radial pulse wave and also quantified that according to the method of Inyoung-Cheongu Comparison Radial Pulse Diagnosis. We defined the jugement standard of radial pulse diagnosis system and then we confirmed the possibility for realization of automatic radial pulse diagnosis in korean traditional medicine. 30545 T00401030545 ^x Microspheres are expected to be applied to biomedical areas such as solid-phase immunoassays, drug delivery systems, immunomagnetic cell separation. To synthesize microspheres for biomedical application, "two stage shot growth method" was developed. The uniformity ratio of synthesized microspheres was always smaller than 1.05. And the surface charge density (or the number of ionizable functional groups) of the microspheres synthesized by "two stage shot growth method" was 6~13 times higher than that of the microspheres synthesized by conventional seeded batch copolymerization. As a previous step for biomedical application, adsorption experiments of bovine albumin on microspheres were carried out under various conditions. The maximum adsorbed amount was obtained in the neighborhood of pH 4.5. Isoelectric point of bovine albumin is pH 5.0, so experimental result shows that it shifted to acid area. The adsorption isotherm was obtained, the plateau region was always reached at 2.Og/L (bulk concentration of bovine albumin).The effect of the kind and the amount of surface functional group was also examined. 30575 T00401030575 ^x A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors' reporting results. Input information was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed information can be transferred for patient diagnosis through LAN(local area network). 30592 T00401030592 ^x In the conventional infrared imaging system, complex infrared lens systems are usually used for directing collimated narrow infrared beams into the high speed 2-dimensional optic scanner. In this paper, a simple reflective infrared optic system with a 2-dimensional optic scanner is proposed for the realization of medical infrared thermography system. It has been experimentally proven that the intfrared thermography system composed of the proposed optic system has the temperature resolution of 0.1˚c under the spatial resolution of lmrad, the image matrix size of 256 X 240, and tile imaging time of 4 seconds. 30593 T00401030593 ^x In this paper, MIIS (Medical Image Information System) has been designed and implemented using INGRES RDBMS, which is based on a client/server architecture. The implemented system allows users to register and retrieve patient information, medical images and diagnostic reports. It also provides the function to display these information on workstation windows simultaneously by using the designed menu-driven graphic user interface. The medical image compression/decompression techniques are implemented and integrated into the medical image database system for the efficient data storage and the fast access through the network. 30594 T00401030594 ^x In this paper, computerized BEAM was implemented for the space domain analysis of EEG. Trans-formation from temporal summation to two-dimensional mappings is formed by 4 nearest point inter-polaton method. Methods of representation of BEAM are two. One is dot density method which classify brain electrical potential 9 levels by dot density of gray levels and the other is colour method which classify brain electrical 12 levels by red-green colours. In this BEAM, instantaneous change and average energy distribution over any arbitrary time interval of brain electrical activity could be observed and analyzed easily. In the frequency domain, the distribution of energy spectrum of a special band can easily be distinguished normality and abnormality. 30608 T00401030608 ^x Laboratory information system (LIS) is a key tool to manage laboratory data in clinical pathology. Our department has developed an information system for routine hematology using down-sized computer system. We have used an IBM 486 compatible PC with 16MB main memory, 210 MB hard disk drive, 9 RS-232C port and 24 pin dot printer. The operating system and database management system were SCO UNIX and SCO foxbase, respectively. For program development, we used Xbase language provided by SCO foxbase. The C language was used for interface purpose. To make the system use friendly, pull-down menu was used. The system connected to our hospital information system via application program interface (API), so the information related to patient and request details is automatically transmitted to our computer. Our system interfaced with fwd complete blood count analyzers(Sysmex NE-8000 and Coulter STKS) for unidirectional data tansmission from analyzer to computer. The authors suggests that this system based on down-sized computer could provide a progressive approach to total LIS based on local area network, and the implemented system could serve as a model for other hospital's LIS for routine hematology. 30609 T00401030609 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed a composite that is consisted of calcium phosphate and collagen. To use as the structural matrix of the composite, collagen was purified from human umbilical cord. The obtained collagen was treated by pepsin to remove telopeptides, and finally, the immune-free atelocollagen was produced: The cross linked atelocollagen was highly resistant to the collagenase induced collagenolysis. The cross linked collagen demonstrated an improved tensile strength. 30618 T00401030618 ^x This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively. 30619 T00401030619 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased. 30620 T00401030620 ^x We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane, To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medical prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volume and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate. 30621 T00401030621 ^x Explosive evaporative removal process of biological tissue by absorption of a CW laser has been simulated by using gelatin and a multimode Nd:YAG laser. Because the point of maximun temperature of laser-irradiated gelatin exists below the surface due to surface cooling, evaporation at the boiling temperature is made explosively from below the surface. The important parameters of this process are the conduction loss to laser power absorption (defined as the conduction-to-laser power parameter, Nk), the convection heat transfer at the surface to conduction loss (defined as Bi), dimensionless extinction coefficient (defined as Br.), and dimensionless irradiation time (defined as Fo). Dependence of Fo on Nk and Bi has been observed by experiment, and the results have been compared with the numerical results obtained by solving a 2-dimensional conduction equation. Fo and explosion depth (from the surface to the point of maximun temperature) are increased when Nk and Bi are increased.To find out the minimum laser power for explosive evaporative removal process, steady state analysis has been also made. The limit of Nk to induce evaporative removal, which is proportional to the inverse of the laser power, has been obtained. 30622 T00401030622 ^x N1 and N2 gross neural action potentials were measured from the round window of the guinea pig cochlea at the onset of the acoustic stimuli. N1-N2 audiograms were made by means of regulating stimulant intensities in order to produce constant N1-N2 potentials as criteria for different input tone pip frequencies. The lowest threshold was measured with an input tone pip I5 dB SPL in intensity and 12 KHz in frequency when the animal was in normal physiological condition. The procedure of experimental measurements is explained in detail. This experimental approach is very useful for the investigation of the Cochlear function. Both noN1inear and active functions of the Cochlea can be monitored by N1-N2 audiograms. 30623 T00401030623 ^x In electrical impedance tomography(EIT), we use boundary current and voltage measurements toprovide the information about the cross-sectional distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. We propose a new image reconstruction method using internal current density data measured by NMR. We obtained a two-dimensional current density distribution within a phantom by processing the real and imaginary MR images from a 4.77 NMR machine. We implemented a resistivity mage reconstruction algorithm using the finite element method and sensitivity matrix. We presented computer simulation results of the mage reconstruction algorithm and furture direction of the research. 30624 T00401030624 ^x A new method of digital image analysis technique for discrimination of cancer cell was presented in this paper. The object image was the Thyroid eland cells image that was diagnosed as normal and abnormal (two types of abnormal: follicular neoplastic cell, and papillary neoplastic cell), respectively. By using the proposed region segmentation algorithm, the cells were segmented into nucleus. The 16 feature parameters were used to calculate the features of each nucleus. A9 a consequence of using dominant feature parameters method proposed in this paper, discrimination rate of 91.11% was obtained for Thyroid Gland cells. 30625 T00401030625 ^x An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients. 30626 T00401030626 ^x Two-Dimensional modelling of the Cochlear biomechanics is presented in this paper. The Laplace partial differential equation which represents the fluid mechanics of the Cochlea has been transformed into two-dimensional electrical transmission line. The procedure of this transformation is explained in detail. The comparison between one and two dimensional models is also presented. This electrical modelling of the basilar membrane (BM) is clearly useful for the next approach to the further. Development of active elements which are essential in the producing of the sharp tuning of the BM. This paper shows that two-dimension model is qualitatively better than one-dimensional model both in amplitude and phase responses of the BM displacement. The present model is only for frequency response. However because the model is electrical, the two-dimensional transmission line model can be extended to time response without any difficult. 30627 T00401030627 ^x A method has been proposed for the fully automatic detection of left ventricular endocardial boundary in 2D short axis echocardiogram using geometric model. The procedure has the following three distinct stages. First, the initial center is estimated by the initial center estimation algorithm which is applied to decimated image. Second, the center estimation algorithm is applied to original image and then best-fit elliptic model estimation is processed. Third, best-fit boundary is detected by the cost function which is based on the best-fit elliptic model. The proposed method shows effective result without manual intervention by a human operator. 30628 T00401030628 ^x The intelligent trajectory control method that controls moving direction and average velocity for a prosthetic arm is proposed by pattern recognition and force estimations using EMG signals. Also, we propose the real time trajectory planning method which generates continuous accelleration paths using 3 stage linear filters to minimize the impact to human body induced by arm motions and to reduce the muscle fatigue. We use combination of MLP and fuzzy filter for pattern recognition to estimate the direction of a muscle and Hogan's method for the force estimation. EMG signals are acquired by using a amputation simulator and 2 dimensional joystick motion. The simulation results of proposed prosthetic arm control system using the EMf signals show that the arm is effectively followed the desired trajectory depended on estimated force and direction of muscle movements. 30638 T00401030638 ^x A new neural network architecture for the recognition of patterns from images is proposed, which is partially based on the results of physiological studies. The proposed network is composed of multi-layers and the nerve cells in each layer are connected by spatial filters which approximate receptive fields in optic nerve fields. In the proposed method, patterns recognition for complicated images is carried out using global features as well as local features such as lines and end-points. A new generating method of matched filers representing global features is proposed in this network. 30659 T00401030659 ^x An implementation scheme of the magnetic nerve stimulator using a switching mode power supply is proposed. By using a switching mode power supply rather than a conventional linear power supply for charging high voltage capacitors, the weight and size of the magnetic nerve stimulator can be considerably reduced. Maximum output voltage of the developed magnetic nerve stimulator using the switching mode power supply is 3, 000 volts and switching time is about 100 msec. Experimental results or human nerve stimulations using the developed stimulator are presented. 30768 T00401030768 ^x In this paper, we describe the design methodology and specifications of the developed module-based bedside monitors for patient monitoring. The bedside monitor consists of a main unit and module cases with various parameter modules. The main unit includes a 12.1" TFT color LCD, a main CPU board, and peripherals such as a module controller, Ethernet LAN card, video card, rotate/push button controller, etc. The main unit can connect at maximum three module cases each of which can accommodate up to 7 parameter modules. They include the modules for electrocardiograph, respiration, invasive blood pressure, noninvasive blood pressure, temperature, and SpO2 with Plethysmograph.SpO2 with Plethysmograph.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
• /
• 한국우주과학회 1993년도 한국우주과학회보 제2권2호
• /
• pp.17-17
• /
• 1993

The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70${\pm}$1.32mmHg/min)compared to CF dialyzers(4.32${\pm}$0.55mmHg/min)(p<0.05). However, there was no observable difference in the UFR between the two dialyzers. Neither APD nor UFR showed any significant increase with an increasing number of reuses for up to more than 20reuses. A substantial number of failures observed in APD(larger than 20mmHe/min)on the reused dialyzers(2 out of 40 CP and S out 26 C-DAK) were attributed to the Possible damage on the fibers. The CF 15-11 HFDs which failed APD test did not show changes in the UFR compared to normal dialyzers indicating that APD is a more sensitive test than UFR test to evaluate the integrity of the fibers. 30527 T00401030527 ^x For quantitative measurement of reflected light from a clinical diagnostic strip, a prototype old reflectance photometer was designed. The strip loader and cassette were made to obtain more accurate reflectance parameters. The strip was illuminated at 45˚c through optical fiber and the intensity of reflected light was determined at rectanguLat angle using a photodiode. The kubelka-munk coefficient and reflection optical density were determined ar four different wavelengths(500,550,570 and 610nm) for blood glucose strip. For higher concentration than 300mg/41 about glucose, a saturation state of abforbance was observed at 500,550 and 570nm. The correlation between glucose concentration and parameters was the best at 610nm. 30535 T00401030535 ^x Radiation-induced fibrosarcoma tumors were grown on the flanks of C3H mice. The mice were divided into two groups. One group was injected with Photofrin II, intravenously (2.5mg/kg body weight). The other group received no Photofrin II. Mice from both groups were irradialed for approximately 15 minutes at 100,300, or 500 mW/cm2 with the argon (488nm/514.5 nm), dye(628nm) and gold vapor (pulsed 628 nm) laser light. A photosensitizer behaved as an added absorber. Under our experimental conditions, the presence of Photolfrin II increased surface temperature by at least 40% and the temperature rise due to 300 mW/cm2 irradiation exceeded values for hyperthermia. Light and temperature distributions with depth were estimated by a computer model. The model demonstrated the influence of wavelength on the thermal process and proved to be a valuable tool to investigate internal temperature rise. 30536 T00401030536 ^x We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs 3nd others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized tomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh IIci computer.The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal flare index are greater by the amount of approximately 8˚ and 0.5, respectively, (2) the shape of the isthmus cross section is more round, and (3) the distance between the teaser trochanter and the proximal border of the isthmus is shelter by about 15 mm. The results suggested that the femoral component suitable for Asians should be different from the currently-used components designed and manufactured mostly by European or American companies. 30537 T00401030537 ^x It is well known that nonlinear propagation characteristics of the wave in the tissue may give very useful information for the medical diagnoisis. In this paper, a new method to detect nonlinear propagation characteristics of the internal vibration in the tissue for the low frequency mechanical vibration by using bispectral analysis is proposed. In the method, low frequency vibration of f0( = 100Hz) is applied on the surface of the object, and the waveform of the internal vibration x (t) is measured from Doppler frequency modulation of silmultaneously transmitted probing ultrasonic waves. Then, the bispectra of the signal x (t) at the frequencies (f0, f0) and (f0, 2f0) are calculated to estimate the nonlinear propagation characteristics as their magnitude ratio, w here since bispectrum is free from the gaussian additive noise we can get the value with high S/N. Basic experimental system is constructed by using 3.0 MHz probing ultrasonic waves and the several experiments are carried out for some phantoms. Results show the superiority of the proposed method to the conventional method using power spectrum and also its usefulness for the tissue characterization. 30541 T00401030541 ^x This paper describes the implementation of a computerized radial pulse diagnosis by aids of a clinical expert. On this base, we composed of the radial pulse diagnosis system in korean traditional medicine. The system composed of a radial pulse wave detection system and a radial pulse diagnosis system. With a detection system, we detected Inyoung and Cheongu radial pulse wave and processed it. Then, we have got the characteristic parameters of radial pulse wave and also quantified that according to the method of Inyoung-Cheongu Comparison Radial Pulse Diagnosis. We defined the jugement standard of radial pulse diagnosis system and then we confirmed the possibility for realization of automatic radial pulse diagnosis in korean traditional medicine. 30545 T00401030545 ^x Microspheres are expected to be applied to biomedical areas such as solid-phase immunoassays, drug delivery systems, immunomagnetic cell separation. To synthesize microspheres for biomedical application, "two stage shot growth method" was developed. The uniformity ratio of synthesized microspheres was always smaller than 1.05. And the surface charge density (or the number of ionizable functional groups) of the microspheres synthesized by "two stage shot growth method" was 6~13 times higher than that of the microspheres synthesized by conventional seeded batch copolymerization. As a previous step for biomedical application, adsorption experiments of bovine albumin on microspheres were carried out under various conditions. The maximum adsorbed amount was obtained in the neighborhood of pH 4.5. Isoelectric point of bovine albumin is pH 5.0, so experimental result shows that it shifted to acid area. The adsorption isotherm was obtained, the plateau region was always reached at 2.Og/L (bulk concentration of bovine albumin).The effect of the kind and the amount of surface functional group was also examined. 30575 T00401030575 ^x A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors' reporting results. Input information was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed information can be transferred for patient diagnosis through LAN(local area network). 30592 T00401030592 ^x In the conventional infrared imaging system, complex infrared lens systems are usually used for directing collimated narrow infrared beams into the high speed 2-dimensional optic scanner. In this paper, a simple reflective infrared optic system with a 2-dimensional optic scanner is proposed for the realization of medical infrared thermography system. It has been experimentally proven that the intfrared thermography system composed of the proposed optic system has the temperature resolution of 0.1˚c under the spatial resolution of lmrad, the image matrix size of 256 X 240, and tile imaging time of 4 seconds. 30593 T00401030593 ^x In this paper, MIIS (Medical Image Information System) has been designed and implemented using INGRES RDBMS, which is based on a client/server architecture. The implemented system allows users to register and retrieve patient information, medical images and diagnostic reports. It also provides the function to display these information on workstation windows simultaneously by using the designed menu-driven graphic user interface. The medical image compression/decompression techniques are implemented and integrated into the medical image database system for the efficient data storage and the fast access through the network. 30594 T00401030594 ^x In this paper, computerized BEAM was implemented for the space domain analysis of EEG. Trans-formation from temporal summation to two-dimensional mappings is formed by 4 nearest point inter-polaton method. Methods of representation of BEAM are two. One is dot density method which classify brain electrical potential 9 levels by dot density of gray levels and the other is colour method which classify brain electrical 12 levels by red-green colours. In this BEAM, instantaneous change and average energy distribution over any arbitrary time interval of brain electrical activity could be observed and analyzed easily. In the frequency domain, the distribution of energy spectrum of a special band can easily be distinguished normality and abnormality. 30608 T00401030608 ^x Laboratory information system (LIS) is a key tool to manage laboratory data in clinical pathology. Our department has developed an information system for routine hematology using down-sized computer system. We have used an IBM 486 compatible PC with 16MB main memory, 210 MB hard disk drive, 9 RS-232C port and 24 pin dot printer. The operating system and database management system were SCO UNIX and SCO foxbase, respectively. For program development, we used Xbase language provided by SCO foxbase. The C language was used for interface purpose. To make the system use friendly, pull-down menu was used. The system connected to our hospital information system via application program interface (API), so the information related to patient and request details is automatically transmitted to our computer. Our system interfaced with fwd complete blood count analyzers(Sysmex NE-8000 and Coulter STKS) for unidirectional data tansmission from analyzer to computer. The authors suggests that this system based on down-sized computer could provide a progressive approach to total LIS based on local area network, and the implemented system could serve as a model for other hospital's LIS for routine hematology. 30609 T00401030609 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed a composite that is consisted of calcium phosphate and collagen. To use as the structural matrix of the composite, collagen was purified from human umbilical cord. The obtained collagen was treated by pepsin to remove telopeptides, and finally, the immune-free atelocollagen was produced: The cross linked atelocollagen was highly resistant to the collagenase induced collagenolysis. The cross linked collagen demonstrated an improved tensile strength. 30618 T00401030618 ^x This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively. 30619 T00401030619 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased. 30620 T00401030620 ^x We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane, To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medical prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volume and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate. 30621 T00401030621 ^x Explosive evaporative removal process of biological tissue by absorption of a CW laser has been simulated by using gelatin and a multimode Nd:YAG laser. Because the point of maximun temperature of laser-irradiated gelatin exists below the surface due to surface cooling, evaporation at the boiling temperature is made explosively from below the surface. The important parameters of this process are the conduction loss to laser power absorption (defined as the conduction-to-laser power parameter, Nk), the convection heat transfer at the surface to conduction loss (defined as Bi), dimensionless extinction coefficient (defined as Br.), and dimensionless irradiation time (defined as Fo). Dependence of Fo on Nk and Bi has been observed by experiment, and the results have been compared with the numerical results obtained by solving a 2-dimensional conduction equation. Fo and explosion depth (from the surface to the point of maximun temperature) are increased when Nk and Bi are increased.To find out the minimum laser power for explosive evaporative removal process, steady state analysis has been also made. The limit of Nk to induce evaporative removal, which is proportional to the inverse of the laser power, has been obtained. 30622 T00401030622 ^x N1 and N2 gross neural action potentials were measured from the round window of the guinea pig cochlea at the onset of the acoustic stimuli. N1-N2 audiograms were made by means of regulating stimulant intensities in order to produce constant N1-N2 potentials as criteria for different input tone pip frequencies. The lowest threshold was measured with an input tone pip I5 dB SPL in intensity and 12 KHz in frequency when the animal was in normal physiological condition. The procedure of experimental measurements is explained in detail. This experimental approach is very useful for the investigation of the Cochlear function. Both noN1inear and active functions of the Cochlea can be monitored by N1-N2 audiograms. 30623 T00401030623 ^x In electrical impedance tomography(EIT), we use boundary current and voltage measurements toprovide the information about the cross-sectional distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. We propose a new image reconstruction method using internal current density data measured by NMR. We obtained a two-dimensional current density distribution within a phantom by processing the real and imaginary MR images from a 4.77 NMR machine. We implemented a resistivity mage reconstruction algorithm using the finite element method and sensitivity matrix. We presented computer simulation results of the mage reconstruction algorithm and furture direction of the research. 30624 T00401030624 ^x A new method of digital image analysis technique for discrimination of cancer cell was presented in this paper. The object image was the Thyroid eland cells image that was diagnosed as normal and abnormal (two types of abnormal: follicular neoplastic cell, and papillary neoplastic cell), respectively. By using the proposed region segmentation algorithm, the cells were segmented into nucleus. The 16 feature parameters were used to calculate the features of each nucleus. A9 a consequence of using dominant feature parameters method proposed in this paper, discrimination rate of 91.11% was obtained for Thyroid Gland cells. 30625 T00401030625 ^x An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients. 30626 T00401030626 ^x Two-Dimensional modelling of the Cochlear biomechanics is presented in this paper. The Laplace partial differential equation which represents the fluid mechanics of the Cochlea has been transformed into two-dimensional electrical transmission line. The procedure of this transformation is explained in detail. The comparison between one and two dimensional models is also presented. This electrical modelling of the basilar membrane (BM) is clearly useful for the next approach to the further. Development of active elements which are essential in the producing of the sharp tuning of the BM. This paper shows that two-dimension model is qualitatively better than one-dimensional model both in amplitude and phase responses of the BM displacement. The present model is only for frequency response. However because the model is electrical, the two-dimensional transmission line model can be extended to time response without any difficult. 30627 T00401030627 ^x A method has been proposed for the fully automatic detection of left ventricular endocardial boundary in 2D short axis echocardiogram using geometric model. The procedure has the following three distinct stages. First, the initial center is estimated by the initial center estimation algorithm which is applied to decimated image. Second, the center estimation algorithm is applied to original image and then best-fit elliptic model estimation is processed. Third, best-fit boundary is detected by the cost function which is based on the best-fit elliptic model. The proposed method shows effective result without manual intervention by a human operator. 30628 T00401030628 ^x The intelligent trajectory control method that controls moving direction and average velocity for a prosthetic arm is proposed by pattern recognition and force estimations using EMG signals. Also, we propose the real time trajectory planning method which generates continuous accelleration paths using 3 stage linear filters to minimize the impact to human body induced by arm motions and to reduce the muscle fatigue. We use combination of MLP and fuzzy filter for pattern recognition to estimate the direction of a muscle and Hogan's method for the force estimation. EMG signals are acquired by using a amputation simulator and 2 dimensional joystick motion. The simulation results of proposed prosthetic arm control system using the EMf signals show that the arm is effectively followed the desired trajectory depended on estimated force and direction of muscle movements. 30638 T00401030638 ^x A new neural network architecture for the recognition of patterns from images is proposed, which is partially based on the results of physiological studies. The proposed network is composed of multi-layers and the nerve cells in each layer are connected by spatial filters which approximate receptive fields in optic nerve fields. In the proposed method, patterns recognition for complicated images is carried out using global features as well as local features such as lines and end-points. A new generating method of matched filers representing global features is proposed in this network. 30659 T00401030659 ^x An implementation scheme of the magnetic nerve stimulator using a switching mode power supply is proposed. By using a switching mode power supply rather than a conventional linear power supply for charging high voltage capacitors, the weight and size of the magnetic nerve stimulator can be considerably reduced. Maximum output voltage of the developed magnetic nerve stimulator using the switching mode power supply is 3,000 volts and switching time is about 100 msec. Experimental results or human nerve stimulations using the developed stimulator are presented. 30768 T00401030768 ^x In this paper, we describe the design methodology and specifications of the developed module-based bedside monitors for patient monitoring. The bedside monitor consists of a main unit and module cases with various parameter modules. The main unit includes a 12.1" TFT color LCD, a main CPU board, and peripherals such as a module controller, Ethernet LAN card, video card, rotate/push button controller, etc. The main unit can connect at maximum three module cases each of which can accommodate up to 7 parameter modules. They include the modules for electrocardiograph, respiration, invasive blood pressure, noninvasive blood pressure, temperature, and SpO2 with Plethysmograph.