• Title/Summary/Keyword: Colloidal stability

Search Result 125, Processing Time 0.024 seconds

A Note on Preparation of Acid Milk Drink Containing Natural Grape Juice (포도과즙(葡萄果汁) 우유(牛乳) 혼합음료(混合飮料)의 시제(試製))

  • Hah, Duk-Mo
    • Korean Journal of Food Science and Technology
    • /
    • v.7 no.4
    • /
    • pp.250-253
    • /
    • 1975
  • The acid milk containing grape juice was prepared from natural grape juice, acid milk and sugar as raw materials, and the stability of the drink was studied. The following results were obtained. 1. The milk mixed with natural grape juice formed coagulated precipitate by coupling of the colloidal materials in the juice with the milk protein and the formation of precipitate was accelerated by pasteurization. 2. The pectin in natural grape juice was affected on the stability of the product, and the stability increased with decrease in the content of pectin. When the content of pectin in natural grape juice was lower than 2.5mg%, the precipitate was not formed in the drink containing 10 to 20% of the juice. 3. The acid milk drink containing the natural grape juice treated with pectinase, not formed precipitate by pasteurization at $85^{\circ}C$, for 20 minutes and can be preserved for long term.

  • PDF

Synthesis and Characterization of Upconversion Nanoparticles for Cancer Therapy

  • Choe, Seung-Yu;Kim, Bo-Bae;Kim, Eun-Bi;Lee, Seung-U;Jeon, Seon-A;Park, Tae-Jeong
    • Proceedings of the Korean Vacuum Society Conference
    • /
    • 2016.02a
    • /
    • pp.420.2-420.2
    • /
    • 2016
  • Various fields have been paid attention to upconversion nanoparticles (UCNPs) because of its unique optical properties. Moreover, to use the UC luminescent techniques through cell images for identified apoptosis/necrosis of cancer cells have been performed. They have been studied for a versatile biomedical application such as a biosensing tool, or delivery of active forms of medicines inside living cells. UCNPs have distinctive characteristics such as photoluminescence, special emission, low background fluorescence signal and good colloidal stability, which have many advantages compared with the organic dyes and quantum dots. UCNPs have not only a great potential for imaging (UC luminescence) but also therapies (photo-thermal therapy, PTT and photo-dynamic therapy, PDT) in cancer diagnostics. Therefore, we report the enhancement of upconversion red emission in NaYF4:Yb3+,Er3+ nanoparticles, synthesized via solid-state method with the thermal decomposition of trifluoroacetate as precursors and organic solvent at a high boiling point. The UCNPs have an emission in the field of near infrared wavelength, cubic shape and nano-size in length. In this study, we will further investigate it for cancer therapy with NIR optical detection onto the solid substrate.

  • PDF

Preparation and Properties of ρ-alumina Bonded Alumina Vibrated Castable Refractory (진동성형용 ρ-알루미나결합 알루미나 캐스터블 내화재료의 제조와 특성)

  • 천승호;전병세
    • Journal of the Korean Ceramic Society
    • /
    • v.40 no.8
    • /
    • pp.791-797
    • /
    • 2003
  • The special binding mechanism developed provides higher density, lower porosity and higher strengths compared with conventional castables. $\rho$-alumina was employed as a binder materials and nano-sized clay colloidal was added to enhance the drying strength preparing for the alumina vibrated castable. Lower water requirement for casting results in a denser product. The mechanical properties with dimensional stability and corrosion resistance behaviors have been improved by controlling the matrix compositions of the castable. The modulus of rupture and compressive strength after heat treatment at 150$0^{\circ}C$ are 92.34 kgf/$\textrm{cm}^2$ and 370 kgf/$\textrm{cm}^2$ respectively. The activation energy of mullite formation is 11.47 kcal/mol.

Bio-functionalized Gold Nanoparticles for Surface-Plasmon- Absorption-Based Protein Detection

  • Kim, Wan-Joong;Choi, Soo-Hee;Rho, Young-S.;Yoo, Dong-Jin
    • Bulletin of the Korean Chemical Society
    • /
    • v.32 no.12
    • /
    • pp.4171-4175
    • /
    • 2011
  • Bio-functionalized gold nanoparticles (AuNPs), which bio-specifically interact with biotin-(strept)avidin, were investigated in this study. AuNPs were functionalized with a synthetically-provided biotin-linked thiol (BLT), which was synthesized by amidation of the active ester of biotin with 2-mercaptoethylamine. The BLT-attached AuNP was bio-specific for streptavidin, making it potentially useful for biosensor applications. To test the bio-specific interactions, the colors, absorption spectra and TEM images were investigated for proteins such as streptavidin, cytochrome C, myoglobin and hemoglobin. The colors and absorption spectra changed when streptavidin was added to the BLT-attached AuNP solution. However, the color and spectra did not change when the other proteins were added to the same solution. These results show that the AuNPs provided a colloidal solution with excellent stability and highly selective absorption characteristics for streptavidin as a target molecule. Proteins were also screened in order to identify a general strategy for the use of optical biosensing proteins based on AuNPs. In addition, TEM images confirmed that streptavidin led the BLT-attached AuNPs to aggregate or precipitate.

Study of Thermostable Chitinase Enzymes from Indonesian Bacillus K29-14

    • Journal of Microbiology and Biotechnology
    • /
    • v.14 no.4
    • /
    • pp.647-652
    • /
    • 2004
  • Thermophilic microorganisms capable of producing chitinase enzymes were screened from samples collected from several crater and geothermal areas. The chitinolytic microorganisms were grown in a selective medium containing colloidal chitin. The Bacillus K29-14 isolate was found to exhibit the highest chitinase and chitin deacetylase activities. When grown in a chitin-containing medium, the isolate produced extracellular chitinase after 24 h of incubation. The optimum temperature and pH for the chitinase were $55^\circ{C}$ and pH 7, respectively, while those for the chitin deacetylase were $55^\circ{C}$ and pH 8, respectively. The thermostable chitinase and chitin deacetylase also retained 80- 90% of their activity after incubation for 5 h at $70^\circ{C}$. The divalent cations $CoCl_2\;and\;NiCl_2$, increased the chitinase activity, while $ZnCl_2$, inhibited the enzyme. The chitin deacetylase was also activated by the presence of $MgCl_2$ and inhibited by $MnCl_2,\;NiCl_2,\;and\;CaCl_2$. A zymogram analysis revealed several forms of chitinase, with a 67 kDa form being the major enzyme.

Particle Size Distribution, Drug Loading Capacity and Release Profiles of Solid Lipid Nanoparticles of Phenylpropionic Acids (페닐프로피온산계 해열진통제 고형지질나노입자의 입도분포와 약물봉입 및 용출특성)

  • Kim, Yoon-Sun;Kim, Kil-Soo
    • Journal of Pharmaceutical Investigation
    • /
    • v.28 no.4
    • /
    • pp.249-255
    • /
    • 1998
  • Solid Lipid Nanoparticle(SLN), one of the colloidal carrier systems, has many advantages such as good biocompatibility, low toxicity and stability. In this paper, the effects of drug lipophilicity and surfactant on the drug loading capacity, particle size and drug release profile were examined. SLNs were prepared by homogenization of melted lipid dispersed in an aqueous surfactant solution. Ketoprofen, ibuprofen and pranoprofen were used as model drugs and tweens and poloxamers were tested for the effect of surfactant. Mean particle size of prepared SLNs was ranged from 100 to 150nm. The drug loading capacity was improved with the most lipophilic drug and low concentration of surfactant. Particle size and polydispersity of SLNs were changed according to the used lipid and surfactant. The rates of drug release were controlled by the loading drug and surfactant concentration. SLN system with effective drug loading efficiency and proper particle size for the intravenous or oral formulation can be prepared by selecting optimum drug and surfactant.

  • PDF

Eco-Friendly Synthesis of Rod-Like Potassium Hexatitanate Particles (친환경 공정에 의한 봉상형 육티탄산칼륨 입자의 제조)

  • Lee, Chongmin;Chang, Hankwon;Jang, Hee Dong
    • Particle and aerosol research
    • /
    • v.13 no.4
    • /
    • pp.183-189
    • /
    • 2017
  • Potassium hexatitanate ($K_2Ti_6O_{13}$) with high thermal insulating capacity, good mechanical properties, and excellent chemical stability are promising functional materials in the field of reinforcing material, heat insulating paints and automotive brake linings. In this study, we successfully synthesized rod-shaped potassium hexatitanate ($K_2Ti_6O_{13}$) by aerosol spray drying and post heat treatment as an eco-friendly process. The $KHCO_3-TiO_2$ porous particles were firstly synthesized from a colloidal mixture of $K_2CO_3$ and $TiO_2$ via aerosol spray drying. Size of $KHCO_3-TiO_2$ porous particles was ranged from $1{\mu}m$ to $5{\mu}m$. The porous particles were then heated to fabricate rod-type $K_2Ti_6O_{13}$. The length and width of rod-type composites were affected by temperature and heating time. The length and width of $K_2Ti_6O_{13}$ were increased by 830 nm and 500 nm, respectively, as the reaction temperature and time increased.

The Effect of Temperature on the Photoluminescence Properties of the InZnP/ZnSe/ZnS (Core/Multishell) Quantum Dots (온도에 따른 InZnP/ZnSe/ZnS (핵/다중껍질) 양자점의 형광 특성 변화)

  • Son, Min Ji;Jung, Hyunsung;Lee, Younki;Koo, Eunhae;Bang, Jiwon
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
    • /
    • v.31 no.7
    • /
    • pp.443-449
    • /
    • 2018
  • We investigated the temperature-dependent photoluminescence spectroscopy of colloidal InZnP/ZnSe/ZnS (core/shell/shell) quantum dots with varying ZnSe and ZnS shell thickness in the 278~363 K temperature range. Temperature-dependent photoluminescence of the InZnP-based quantum dot samples reveal red-shifting of the photoluminescence peaks, thermal quenching of photoluminescence, and broadening of bandwidth with increasing temperature. The degree of band-gap shifting and line broadening as a function of temperature is affected little by shell composition and thickness. However, the thermal quenching of the photoluminescence is strongly dependent on the shell components. The irreversible photoluminescence quenching behavior is dominant for thin-shell-deposited InZnP quantum dots, whereas thick-shelled InZnP quantum dots exhibit superior thermal stability of the photoluminescence intensity.

Characteristics on Cured Thin Film of Sol-Gel Materials Synthesized from CS/MTMS/ES (CS/MTMS/ES 졸겔코팅제 경화박막의 특성)

  • Myung, In-Hye;Kang, Dong-Pil;Ahn, Myeong-Sang;Na, Moon-Kyong;Kang, Young-Taec
    • Proceedings of the KIEE Conference
    • /
    • 2005.07c
    • /
    • pp.1930-1932
    • /
    • 2005
  • Colloidal Silica(CS)/methyltrimethoxy silane(MTMS) and CS/MTMS/epoxy silane(Es) sol solutions were prepared in variation with synthesizing parameters such as kinds of CS, kinds of silane and reaction time. In order to understand its physical and chemical properties, sol-gel coating films on glass were fabricated. In the case of CS/MTMS sol, the coating films had high contact angle and more enhanced flat surface than those in the case of CS/MTMS/ES sol. Also, the coating films obtained from single CS had a better flat surface than those obtained from mixed CS. In the case of thermal stability, thermal dissociation of CS/MTMS and CS/MTMS/ES sol-gel coating films did not occur up to $550^{\circ}C$ and $440^{\circ}C$ respectively. The thickness of coating films obtained from CS/MTMS sol increased than those of CS/MTMS/ES sol. In addition, the coating films obtained from single CS were more thicker than those obtained from mixed CS.

  • PDF

Synthesis of Polystyrene Nanoparticles with Monodisperse Size Distribution and Positive Surface Charge Using Metal Stearates

  • Kim, Mi-Sun;Kim, Seok-Ki;Lee, Jun-Young;Cho, Seung-Hyun;Lee, Ki-Hoon;Kim, Jun-Kyung;Lee, Sang-Soo
    • Macromolecular Research
    • /
    • v.16 no.2
    • /
    • pp.178-181
    • /
    • 2008
  • Polystyrene (PS) nanospheres with a monodisperse size distribution, positive surface charge and high molecular weight were successfully synthesized using various types of metal stearates in an aqueous NaOH medium. The diameter of the PS nanospheres was controlled from 80 to 450 nm by changing the type of metal stearate. It was also found that controlling the NaOH concentration in solution was important for producing monodisperse PS nanoparticles. The nanospheres prepared with zinc stearate possessed a positive surface charge of 60 to 80 mV, confirming that PS particles were functionalized with metal stearates. It is believed that the metal stearates provide PS particles with not only colloidal stability but also a positive surface charge.