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Studies on the Constituents of Polygonum sp. (호장(虎杖)의 성분(成分)에 관(關)한 연구(硏究))

  • Kim, Tae-Hee;Lee, Jong-Hee;Yang, Ki-Sook;Kim, Myung-Ja;Yoo, Yon-Hee
    • Korean Journal of Pharmacognosy
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    • v.9 no.2
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    • pp.89-91
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    • 1978
  • Free amino acids and mineral substance in radix of Polygonum cuspidatum, Polygonum elliptica, and Polygonum sachalinense were analyzed by amino acid autoanalyzer and atomic absorption spectrophotometer. Gross contents of free amino acids in root of P. cuspidatum and P. elliptica are 12.99mg/g and 9.58mg/g respectively. The analysis of inorganic constituents of Polygonum sp. showed that it generally contains copper, iron, manganese, zinc, potassium and potassium salt.

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Synthesis of Heterocycle-linked Thioureas and Their Inhibitory Activities of NO Production in LPS Activated Macrophages

  • Cheon, Ye-Jin;Gim, Hyo-Jin;Jang, Hee-Ryun;Ryu, Jae-Ha;Jeon, Raok
    • Bulletin of the Korean Chemical Society
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    • v.31 no.1
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    • pp.27-30
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    • 2010
  • A series of thioureas were synthesized as inhibitors of NO production in lipopolysaccharide-activated macrophages. We investigated the effect of lipophilic moiety and N-substituents of the thioureas on the activity. Phenoxazine and carbazole-containing derivatives revealed higher activity than indole-containing thioureas. The appropriate spacer between lipophilic tail and thiourea head and methyl substituent at N3 position of thiourea brought beneficial effect on the inhibition of NO production. Among prepared compounds, phenoxazine-containing derivative 2a was the most potent with $2.32 {\mu}M$ of $IC_{50}$ value. RT-PCR analysis suggested that the prepared thioureas inhibited NO production through the suppression of iNOS mRNA expression.

Female Crime Prevention System using safety delivery App in Smart Mobile Environments (스마트 모바일 환경에서의 안심택배 앱을 이용한 여성범죄 예방 시스템)

  • Kim, Seokhun;Yu, Hyesu;Yeo, Minji;Song, Miyeong;Sok, Yunyoung
    • Proceedings of the Korean Society of Computer Information Conference
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    • 2014.01a
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    • pp.261-262
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    • 2014
  • 최근 택배산업의 급격한 성장과 모바일 웹앱 환경의 급격한 발달 및 택배물량이 증가하면서 택배 피해 사례도 증가하고 있다. 현재 택배서비스 이용시 피해 발생시 책임소재 입증불가 및 책임회피의 문제점이 대두되었고, 택배기사를 사칭한 각종 여성 범죄 사고가 증가하고 있다. 본 논문에서는 모바일 환경에서의 택배정보 및 위치정보를 확인할 수 있도록 음성을 저장 및 인식할 수 있는 안심택배 관리 시스템을 연구하고 설계하였다.

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Assessment on combined repeated dose and reproduction/developmental toxicity of benzoyl peroxide

  • Sanghwan Song;Kim, Su-Hyon;Heekyung Bae;Lee, Moon-Soon;Park, Kwangsik
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2002.11b
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    • pp.171-171
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    • 2002
  • This study was carried out by an Korean GLP laboratory to assess the combined repeated dose, reproduction and developmental toxicity of benzoyl peroxide for OECD SIDS(Screening Information Data Set) program. Male and female Sprague Dawley rats were exposed to benzoyl peroxide at levels of 0, 250, 500 and 1,000 mg/kg/day for 29 days for male and for 41-51 days for female.(omitted)

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Service for connecting Shopping mall using Image Search (이미지 검색을 이용한 쇼핑몰 연계 서비스)

  • Ha, Yan;Jeong, Ji-Won;Kim, Ru-Bi;Choi, Ji-Yeon;Heo, Jeong-Yun
    • Proceedings of the Korean Society of Computer Information Conference
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    • 2011.06a
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    • pp.173-174
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    • 2011
  • 본 논문에서는 그림을 그려서 원하는 이미지를 그리고, 이를 인식하여 상품을 찾아주는 정보전달 방식을 제안한다. 사용자가 원하는 이미지에 맞는 상품을 검색할 수 있도록 하는데, 그림 그리기가 가능하고, 개인의 "공감", "신뢰"를 실현하는 공간과 개인과 기업을 연결해주는 정보성 검색으로 쇼핑몰을 연계하는 것을 목표로 한다. 본문 내에서는 고객이 직접 찾는 디자인을 간단히 그리면 비슷한 그림의 상품이 나오게 되는 공간을 제작, 상품이 나오면 기업과의 연계를 통하여 구매로까지 이어질 수 있는 공간을 제시하는 것을 목표로 한다.

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Dissolution Test for Indomethacin by the Portable Near-Infrared(NIR) System

  • Kim, Do-Hyung;Lim, Hun-Rang;Chang, Soo-Hyun;Woo, Young-Ah;Kim, Hyo-Jin
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.399.3-399.3
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    • 2002
  • Near-infrared (NIR) system was used to determine rapidly and simply indomethacin in buffer solution for a dissolution test for tablets and capsules. Indomethacin standards were prepared ranging from 10 to 50ppm using mixture of phosphate buffer(pH 7,2) and water(1:4), The near infrared(NIR) transmittance spectra of indomethacin standard solutions were collected by using a quartz cell in 1 mm and 2mm pathlength, Partial least-square regression (PLSR) was explored to develop calibration models over the spectral range 1100-1700nm. (omitted)

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Synthesis of Quinolinones for Novel Flavonoid Derivatives

  • Park, Myung-Sook;Park, Hae-Sun;Yoon, Myung-Sun;Kim, Nan-Young;Lee, Jae-In
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.241.2-241.2
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    • 2003
  • We report the synthesis of key intermediates for the development novel flavonoid derivatives with potential antiinflammatory activity and propose a mechanism of the one-pot reaction. The various amines (1) for this work were commercially available. Secondary amines (2) were formed by nucleophilic attraction using ethyl benzoylacetate. The C-N bond formation proceeded at refluxing in toluene with catalytic amount of p-toluenesulfonic acid and a removal of water was important in this reaction. (omitted)

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Further Studies on Anti-angiogenic Activity of Gardenia jasminoides Fruit

  • Kim, Sun-Hyoung;Koo, Hye-Jin;Won, So-Young;Jung, Hyun-Joo;Park, Eun-Hee
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.266.1-266.1
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    • 2002
  • Gardenia jasminoides Ellis has been used in traditional medicine for the treatment of inflammation. jaundice, headache, fever and hypertension. The 70% ethanolic extract of gardenia fruit was previously shown to possess strong anti-angiogenic activity in the CAM assay. In this work, hexane, ethyl acetate. n-butanol and aqueous fractions were prepared in succession from the 70% ethanolic extract. (omitted)

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