• Title/Summary/Keyword: College of Engineering

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Simulation of photon propagation for transcutaneous optical communication (피부투과 광통신을 위한 세포내 광진행 시뮬레이션)

  • Lee, J.J.;Kim, W.E.;Lee, J.H.;Choi, J.H.;Ahn, J.M.;Choi, W.W.;Park, S.K.;Choi, J.S.;Kim, H.C.;Min, B.G.
    • Proceedings of the KOSOMBE Conference
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    • v.1996 no.11
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    • pp.65-67
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    • 1996
  • Optical property of tissue is characterized by its high scattering of light. In near infrared range$(800{\sim}1200nm)$ scattering is dominant than absorption. Communication using NIR through tissue is applicable to immplantable device. In this paper, simulation of unit impulse response of light in tissue is carried out to estimate the amplitude, phaselength and phaselength deviation.

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NaCl Concentration-Dependent Aminoglycoside Resistance of Halomonas socia CKY01 and Identification of Related Genes

  • Park, Ye-Lim;Choi, Tae-Rim;Kim, Hyun Joong;Song, Hun-Suk;Lee, Hye Soo;Park, Sol Lee;Lee, Sun Mi;Kim, Sang Hyun;Park, Serom;Bhatia, Shashi Kant;Gurav, Ranjit;Sung, Changmin;Seo, Seung-Oh;Yang, Yung-Hun
    • Journal of Microbiology and Biotechnology
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    • v.31 no.2
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    • pp.250-258
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    • 2021
  • Among various species of marine bacteria, those belonging to the genus Halomonas have several promising applications and have been studied well. However, not much information has been available on their antibiotic resistance. In our efforts to learn about the antibiotic resistance of strain Halomonas socia CKY01, which showed production of various hydrolases and growth promotion by osmolytes in previous study, we found that it exhibited resistance to multiple antibiotics including kanamycin, ampicillin, oxacillin, carbenicillin, gentamicin, apramycin, tetracycline, and spectinomycin. However, the H. socia CKY01 resistance pattern to kanamycin, gentamicin, apramycin, tetracycline, and spectinomycin differed in the presence of 10% NaCl and 1% NaCl in the culture medium. To determine the mechanism underlying this NaCl concentration-dependent antibiotic resistance, we compared four aminoglycoside resistance genes under different salt conditions while also performing time-dependent reverse transcription PCR. We found that the aph2 gene encoding aminoglycoside phosphotransferase showed increased expression under the 10% rather than 1% NaCl conditions. When these genes were overexpressed in an Escherichia coli strain, pETDuet-1::aph2 showed a smaller inhibition zone in the presence of kanamycin, gentamicin, and apramycin than the respective control, suggesting aph2 was involved in aminoglycoside resistance. Our results demonstrated a more direct link between NaCl and aminoglycoside resistance exhibited by the H. socia CKY01 strain.

In vitro Estimation of Cardiac Output for the TAH using an Adaptive Fuzzy Identifier

  • Choi, W.W.;Jo, Y.H.;Ahn, J.M.;Park, S.K.;Choi, J.S.;Om, K.S.;Lee, J.J.;Choi, J.H.;Kim, H.C.;Min, B.G.
    • Proceedings of the KOSOMBE Conference
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    • v.1996 no.11
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    • pp.263-267
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    • 1996
  • An estimation algorithm based on training of fuzzy logic system using back-propagation is proposed, in this paper, for determining cardiac output in the TAH. The proposed estimation utilizes only a motor current waveform generated from the moving actuator of the electromechanical TAH without using any extra transducers as an information source for estimation. In in vitro tests, the resultant estimation performance was acceptable to alppy the proposed algorithm to animal experiments and further clinical applications.

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Comparative Study of the Difference in Behavior of the Accessory Gene Regulator (Agr) in USA300 and USA400 Community-Associated Methicillin-Resistant Staphylococcus aureus (CA-MRSA)

  • Lee, Hye Soo;Song, Hun-Suk;Lee, Hong-Ju;Kim, Sang Hyun;Suh, Min Ju;Cho, Jang Yeon;Ham, Sion;Kim, Yun-Gon;Joo, Hwang-Soo;Kim, Wooseong;Lee, Sang Ho;Yoo, Dongwon;Bhatia, Shashi Kant;Yang, Yung-Hun
    • Journal of Microbiology and Biotechnology
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    • v.31 no.8
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    • pp.1060-1068
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    • 2021
  • Community-associated Methicillin-Resistant Staphylococcus aureus (CA-MRSA) is notorious as a leading cause of soft tissue infections. Despite several studies on the Agr regulator, the mechanisms of action of Agr on the virulence factors in different strains are still unknown. To reveal the role of Agr in different CA-MRSA, we investigated the LACΔagr mutant and the MW2Δagr mutant by comparing LAC (USA300), MW2 (USA400), and Δagr mutants. The changes of Δagr mutants in sensitivity to oxacillin and several virulence factors such as biofilm formation, pigmentation, motility, and membrane properties were monitored. LACΔagr and MW2Δagr mutants showed different oxacillin sensitivity and biofilm formation compared to the LAC and MW2 strains. Regardless of the strain, the motility was reduced in Δagr mutants. And there was an increase in the long chain fatty acid in phospholipid fatty acid composition of Δagr mutants. Other properties such as biofilm formation, pigmentation, motility, and membrane properties were different in both Δagr mutants. The Agr regulator may have a common role like the control of motility and straindependent roles such as antibiotic resistance, biofilm formation, change of membrane, and pigment production. It does not seem easy to control all MRSA by targeting the Agr regulator only as it showed strain-dependent behaviors.

The relationship among self-efficacy, engineering interest and social support on adjustment to college and learning persistence in first year engineering college students (공과대학 신입생의 자기효능감, 공학흥미, 사회적지지, 대학생활적응 및 학업지속의향 간의 관계)

  • Lee, Myunghwa;Lee, Jeongmin
    • Journal of Engineering Education Research
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    • v.21 no.6
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    • pp.13-24
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    • 2018
  • The purpose of this research is to investigate the relationship among self-efficacy, engineering interest and social support on adjustment to college and learning persistence in first year engineering college students. The participants were 74 freshman of engineering college students, SPSS and SmartPLS were used to analyze the data. The key findings revealed were as follows: First, self-efficacy, engineering interest and social support had a significant influence on adjustment to college. Second, engineering interest and adjustment to college had a significant influence on learning persistence. This research suggested the implications for adjustment to college and learning persistence in engineering education.