• 대한두경부종양학회지
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• 제36권2호
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• pp.73-77
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• 2020

Ovarian cancer is common malignant disease with high mortality in the female. However, lymph node metastasis in the head and neck of ovarian cancer is very rare than in para-aortic, pelvic lymph node. A 49-year-old female patient came to our clinic with a left neck mass. After total thyroidectomy and left selective neck dissection for the cervical neck level II, III, IV, V, VI for ovarian cancer and thyroid cancer, she had already undergone chemotherapy (Paclitaxel+Carboplatin) 18 month ago. CT scan showed only lymph node enlargement in left neck level II. Positron emission tomography-computed tomography (PET-CT) revealed a hypermetabolic lesion in same area but no other hypermetabolic lesion, especially in the pelvic and abdominal cavity. Fine needle aspiration cytology revealed metastatic carcinoma. The serum level of CA-125 was elevated to 43.8U/mL, whereas other tumor markers (CA 19-9, CEA) were in the normal range. She underwent a revision of selective neck lymph node dissection for the cervical neck levels I, II, and III, and on the review of surgical pathology, metastatic carcinoma was suspected. Thus, we performed immunohistochemical staining for the tissue; as a result, it was finally diagnosed as metastatic ovarian cancer (positive for CK7, ER and PR, and negative for CK20). Adjuvant chemotherapy (Paclitaxel+Carboplatin) was planned on the tumor board, and the patient successfully received chemotherapy.

• 한국작물학회지
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• 제5권1호
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• pp.51-56
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• 1969

소두의 형질상호간의 표현형상관, 유전상관 그리고 환경상관을 알고자 1963년 재래종 적두$\times$일본종서병을 지배하여 1967년 F4 세대 40계통을 재료로 선발실험을 하였다. 조사형채은 개화일수, 경직경, 분지수 1주래수, 입중, 전식물체중, 100입중의 8개형질이었고 이들 각형질상호간의 표현형공분산, 유전공분산, 환경공분산과 각형질의 표현형분산을 본봐 그 결과는 제1표와 같이 환경공분산과 표현형분산은 형질 또는 형질간의 조합에 따라 변동이 심하나 대체로 유전공분산은 표현형공분산보다 다소 크다.(표1) 각형질 상호간의 표현형상관, 유전상관, 환경상관을 계산한바 제2표와같이 대체로 유전상관의 값은 표현형상관보다 그값이 크다. (표2), 수량과의 상관을 보면 1주래수가 수량에 영향한다고 보이며 1주래수가 많은 것은 입수도 많은 것이 당연하므로 소두는 대두와 달리 수량과 개화일수 또는 수량과 경직경 같에는 상관이 보이지 아니하므로 1주래수와 1주입수의 2개형질은 소두의 다수계통, 선택을 위한 중요한 선택형질이 될것으로 믿는다.

• 대한의생명과학회지
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• 제9권4호
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• pp.195-201
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• 2003

Aromatic hydrocarbons are of major concern among genotoxic chemicals due to their toxicity and persistence. Some microorganisms can utilize aromatic hydrocarbons as carbon and energy sources by inducing expression of catabolic operon(s). The XylR regulatory protein activates transcription of the catabolic enzymes to degrade BTEX (benzene, toluene, ethylbenzene, and xylene) from its cognate promoters, Pu and Ps upon exposure of the cells to the aromatic hydrocarbons. The activity of XylR on the promoters was previously monitored using luciferase luc reporter system. The xylR, its promoter Pr and the promoter Po for the phenolic compound catabolic operon were introduced upstream of firefly luciferase luc in the pGL3b vector to generate about 7.1 kb of pXRBTEX. Here E. coli harboring the plasmid was freeze-dried under various conditions to fin,d optimal conditions for storage and transport. The cell viability and luciferase activity were maintained better, when the cells were freeze-dried at -7$0^{\circ}C$ in the addition of the 10% skim milk or 12% sucrose. However, coaddition of protectants such as 10% skim milk plus 10% glucose or 12% sucrose plus 10% glucose, resulted in much better viability and bioluminescence activity compared with the effect of single addition of each protectant. In addition, it was shown that the freeze-dried cells maintained almost intact bioluminescent activities and cell viability for at least 1 week after freeze-drying. This work demonstrated that the properly freeze-dried recombinant bacterial cells could be utilized as a whole-cell biosensor for simple and rapid monitoring of BTEX in the environment.

• 한국환경과학회지
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• 제23권7호
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• pp.1321-1332
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• 2014

The key objective of this study was to evaluate trophic state and empirical water quality models along with analysis of fish trophic guilds in relation to water chemistry (N, P). Trophic state index (TSI), based on total phosphorus (TP) and chlorophyll-a (CHL), ranged between oligotrophic and hypereutrophic state, by the criteria of Nurnberg(1996), and was lower than the trophic state of total nitrogen (TN). Trophic relations of Secchi depth (SD), TN, TP, and CHL were compared using an empirical models of premonsoon (Pr), monsoon (Mo), and postmonsoon (Po). The model analysis indicated that the variation in water transparency of Secchi depth (SD) was largely accounted (p < 0.001, range of $R^2$ : 0.76-0.80) by TP during the seasons of Mo and Po and that the variation of CHL was accounted (p < 0.001, $R^2=0.70$) up to 70% by TP during the Po season. The eutrophication tendency, based on the $TSI_{TP}$ vs. $TSI_{N:P}$ were predictable ($R^2$ ranged 0.85-0.90, p < 0.001), slope and y intercept indicated low seasonal variability. In the mean time, $TSI_{N:P}$ vs. $TSI_{CHL}$ had a monsoon seasonality in relation to values of $TSI_{N:P}$ during the monsoon season due to a dilution of reservoir waters by strong monsoon rainfall. Trophic compositions of reservoir fish reflected ambient contents of TN, TP, and CHL in the reservoir waters. Thus, the proportions of omnivore fish increased with greater trophic conditions of TP, TN and CHL and the proportions of insectivore fish decreased with greater trophic conditions.

• Asian Pacific Journal of Cancer Prevention
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• 제15권14호
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• pp.5535-5538
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• 2014

Background: To determine the amount of co-expression of IDO and EGFR in breast cancer patients. Materials and Methods:In order to obtain the distribution of co-expression of IDO and EGFR in breast cancer, we tested 110 breast cancer paraffin tissue blocks with immunohistochemical methods. Then we investigated the relationship between the diagnostic and pathologic characteristics (tumor size, lymph node status, histologic grade, the gene expression of ER, PR, HER2, p53, Ki67 and PCNA) with the situation of co-expression of IDO and EGFR by reviewing the medical records of 32 breast cancer patients. Results: Among 110 breast cancers, 32 cases demonstrated IDO and EGFR co-expression (29.1%), IDO and EGFR synchronous co-expression being found in 19.1% and asynchronous in 10.0%. Conclusions: IDO and EGFR were co-expressed in breast cancer, including synchronous and asynchronous co-expression. The results suggest that considering IDO and EGFR as two indicators for breast cancer treatment or prognosis analysis provides a potential option of individual treatment for the portion of breast cancer patients with co-expression of IDO and EGFR.

• Journal of Periodontal and Implant Science
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• 제32권3호
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• pp.631-642
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• 2002

The present study evaluated of regeneration effect of platelet rich plasma on the treatment of classII furcation involvement, with allograft in humans. The control was treated without bioabsorbable membrane, and the test was treated with bioabsorbable membrane. Pocket depth, clinical attachment level, and gingival recession were measured at baseline, postoperative 3, 6months. Both groups were statistically analyzed by Wilcoxon signed Ranks Test & Mann-whitney Test using SPSS program (5% significance level). The results were as follows: 1. The change of pocket depth and clinical attachment level in both groups was decreased significantly at 3, 6months.(p<0.05) 2. The change of gingival recession in both groups was increased significantly at 3, 6months than at baseline.(p (0.05) 3. The change of pocket depth and clinical attachment level in both groups was increased significantly at 3, 6months, but there were no statistically or clinically significant differences with both groups. 4. The change of gingival recession in both groups was increased significantly at 3, 6months, but there were no statistically or clinically significant differences with both groups. 5. The significant reduction of the pocket depth and clinical attachment level exhibited marked changes at 3 months in both groups. In conclusion, the results of this study suggest that there are no statistically or clinically significant differences between with and without bioabsorbable membrane on treatment of classII furcations using allograft and PRP

• Radiation Oncology Journal
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• 제11권1호
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• pp.83-90
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• 1993

During the period from January, 1975, to June, 1989, one hundred patients with histopathologically proven polymorphic reticulosis in the upper respiratory tract were treated with radiation therapy and the analysis of treatmemt results was undertaken. One hundred patients (69 males, 31 females) with a mean age of 46 years (range 12-79 years) were presented. Nasal cavity was the most frequent site of involvement ($56{\%}$), and 44 cases had multifocal sites of involvement. The incidence of cervical lymph node metastasis at initial diagnosis was $24{\%}$. Staging was determined by Ann-Arbor classification, retrospectively. The number of patients of stage IE, IIE, IIIE and IVE were 35, 60, 1, and 4, respectively. The overall 5 year actuarial survival rates were $38.4{\%}$. The difference in 5 year survival rates between patients with stage IE and IIE, with solitary and multiple, with CR and PR after irradiation were significant statistically. For the analysis of failure patterns, failure sites include the following: local failure alone (30/55=$54.6{\%}$), systemic failure alone (9/55=$16.4{\%}$), both local and systemic failure (16/55=$29.0{\%}$). Retrograde slide review was available in 29 cases of PMR with respect to histopathologic bases, and immunohistochemical studies were performed using MT1 and DACO-UCHL-1 as T-cell markers, MB2 as a B-cell marker and alpha-1-antichymotrypsin as a histiocytic markers. All that 29 cases showed characteristic histologic features similar to those of peripheral T-cell lymphoma and showed positive reactio to the T-cell marker. These findings suggest strongly that quite a significant portion of PMR may be in fact T-cell lymphoma.

• 디지털융복합연구
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• 제15권3호
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• pp.99-106
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• 2017

본 연구는 직업전문학교 재학생의 학습동기와 학습 자율성이 직무창의성과 전공만족도 및 학교만족도와 어떤 영향관계인지 파악하는 것을 연구목적으로 하였다, 국내 전문직업학교가 비교적 최근에 활성화되었고 학술적 연구가 매우 부족한 현실이다. 직업전문학교 제과제빵 전공 재학생 설문조사를 통해 이론적 선행연구에 근거한 연구가 설들을 검증하였다. 직무창의성은 학생의 학습동기와 학습 자율성의 복합적인 영향을 받는 것으로 나타났다. 내재적 학습동기와 학습 자율성은 전공만족도에 유의한 수준의 긍정적 영향을 미치나 외재적 학습동기는 전공만족도에 부적 영향관계를 보였다, 직업전문학교 교육은 실무중심의 기술전달 방식 위주라서 본 연구는 학습동기, 창의성, 학습 자율성 등의 심리적 성향이 학생 만족도에 미치는 영향을 파악하였고 교과정책 반영에 참고할 결과를 제시하였다. 향후 신입생 홍보나 교과운영, 학사관리를 위하여 더 체계적이며 복합적인 연구가 필요하다.

• 대한한방부인과학회지
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• 제24권4호
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• pp.50-61
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• 2011

Purpose: This study was performed to analyse autonomic nerve function of some examinees with dysmenorrhea by comparing the characteristics of dysmenorrhea patients' Heart Rate Variability(HRV) in examinees group with non-examinees group. Methods: We studied 110 patients visiting OO Korean hospital to take medical treatment for dysmenorrhea from September, 2006 to August, 2010. The subjects were categorized in two groups, 36 examinees and 57 non-examinees controls. We investigated the difference of HRV between two groups by student's T-test using SPSS for Windows(version 12.0). Results: 1. SDNN in examinees group is statistical significantly lower than non-examinees group. RMS-SD in examinees group is lower than non-examinees group non-statistical significantly. Mean PR in examinees group is higher than non-examinees group non-statistical significantly. 2. VLF, ln TP, ln VLF and ln HF are statistically significantly lower than non-examinees group. TP, HF and ln LF are lower than non-examinees group non-statistical significantly. LF is higher than non-examinees group non-statistical significantly. Conclusions: The results suggest that stress is related to especially examinees in dysmenorrhea patients by effecting autonomic nerve function. HRV can be useful to diagnose examinees' dysmenorrhea. The further studies would be needed to study about relation between stress, dysmenorrhea and HRV for settling this.

• Steel and Composite Structures
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• 제49권2호
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• pp.215-230
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• 2023

Cable-girder anchorage joint is the critical part of cable-supported bridges. Tensile-plate anchorage (TPA) is one of the most commonly used types of cable-girder anchorage joints in steel girder cable-supported bridges. In recent years, it has been proposed by bridge designers to apply TPA to concrete girder cable-supported bridges to form composite cable-girder anchorage joint (CCGAJ). In this paper, the mechanical performance of CCGAJ under tensile force is studied through experimental and numerical analyses. Firstly, the effects of the external prestressing (EP) and the bearing plate (BP) on the mechanical performance of CCGAJ were investigated through three tests. Then, finite element model was established for parametrical study, and was verified by the experimental results. Then, the effects of shear connector forms, EP, BP, vertical rebar rate, and perforated rebar rate on the tensile capacity of CCGAJ were investigated through numerical analyses. The results show that the tensile capacity of CCGAJ depends on the first row of PR. The failure mode of CCGAJ using headed stud connectors is to form a shear failure surface at the end of the studs while the failure mode using PBLs is similar to the bending of a deep girder. Finally, based on the strut-and-tie model (STM), a calculation method for CCGAJ tensile capacity was proposed, which has a high accuracy and can be used to calculate the tensile capacity of CCGAJ.