• Title/Summary/Keyword: College Faculty

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Edible mushroom (Pleurotus cornucopiae) extract vs. glibenclamide on alloxan induced diabetes: sub-acute in vivo study of Nrf2 expression and renal toxicity

  • Chinedu Godwin Uzomba;Uchenna Kenneth Ezemagu;Mary-Sonia Ofoegbu;Njoku Lydia;Essien Goodness;Chinedum Emelike;Uchewa Obinna;Alo Joseph Nwafor;Ejikeme Felix Mbajiorgu
    • Anatomy and Cell Biology
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    • v.57 no.3
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    • pp.446-458
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    • 2024
  • The study aims to compare the action of Pleurotus cornucopiae and glibenclamide on alloxan-induced diabetes and ascertain how an aqueous extract of the edible mushroom regulates the expression of nuclear factor erythroid 2-related factor 2 (Nrf2), oxidative stress biomarkers and renal toxicity in a diabetic male Wistar rat model. Twenty-five adult male Wistar rats were randomly grouped into five groups with five rats per. Group 1 and those in the treatment groups received normal feed and water ad libitum. Group 2 received intraperitoneal administration of alloxan monohydrate (150 mg/kg body weight). Group 3 received alloxan monohydrate and glibenclamide (5 mg/kg body weight bwt), group 4 received alloxan monohydrate plus the extract (250 mg/kg bwt) and group 5 received alloxan monohydrate plus the extract (500 mg/kg bwt). The administration of glibenclamide plus the extract was oral for 14 days. Glibenclamide and the extract lowered blood glucose level, catalase, and glutathione peroxidase activities, increased the superoxide dismutase (SOD) activity in rats with alloxan induced diabetes. The extract at 500 mg/kg bwt reduced the plasma urea and sodium concentration in the treated rats. The extract and glibenclamide could detoxify alloxan and restore its induced renal degeneration and glomeruli atrophy, intra renal hemorrhage and inflammation and oxidative biomarkers through activation of Nrf2 expression. The drug glibenclamide and P. cornucopiae have appreciable hypoglycemic activity and potential to restore the normal renal architecture in the rats, hence they offer similar curative effects. Additionally, the extract at 500 mg/kg bwt activated SOD and Nrf2 expression more than glibenclamide in rats with alloxan-induced diabetes.

Nursing Faculty Competence and Nursing Faculty's Attitude for Lecture Evaluation (간호학교수의 교수능력과 강의평가에 대한 태도조사)

  • Suh, Moon-Ja;Do, Bok-Neum;Park, Chun-Ja;Kim, Kem-Soon;Im, Nan-Young;Choi, Kyung-Sook;Lee, Sun-Ok;Kim, Soon-Re;Choi, S-Mi;Park, Young-Im;Choi, Sang-Soon;Jung, Eun-Soon;Cho, Nam-Ok
    • The Journal of Korean Academic Society of Nursing Education
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    • v.9 no.2
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    • pp.320-328
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    • 2003
  • Nurse educators' competence is considered to be important in relation to the quality of education for nursing students. The purpose of this study was to identify the nursing faculty competence and attitude for lecture evalutaion, evlauated by nursing faculty. This article presented results focusing on South Korean nursing faculty's attutude for lecture evalutaion done by students and their opinion of the importance of nurse educator competence domains. The data collection was done from October, 2002 to August, 2003 and 151 subjects were used for the analysis. The Ideal Nursing Teacher Questionnaire was used to assess nurse faculty competence. The results showed that all of the lecture were evaluated and 59.6% of clinical practice was evaluated by nursing studuents. Nursing faculty thought that lecture evaluation by students was resonable, even though it was stressful. The most important among 5 domains of nurse educators' competence assessed by nursing faculty was nursing competence. Moreover nursing faculty responed that teaching skills domain and evaluation skills domain were more important than relationship with students domain and personality factors domain. Compared to young nursing faculty, nursing faculty who was old aged reported that nurse educators' competences in 4 domains of nursing competence, teaching skills, evaluation skills and relationship with students were more important.

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Pereeption on curriculum reformation and evalution of medical school (의과대학 교육과정 개편에 대한 인식과 교육과정 평가)

  • Lee, Sookon;Chung, MyungHyun;Yang, Eunbae
    • Korean Medical Education Review
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    • v.9 no.2
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    • pp.1-12
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    • 2007
  • Purpose: The aim of this study is to identify the elements of success in curriculum reformation using focus group interview and faculty survey. Methods: We analyzed the 105 questionnaires that were collected horn 450 faculties in Yonsei University College of Medicine from September 1 to September 12, 2005. The interview of focus group was conducted to 105 faculty and students using 10 interview questions from July 25 to August 29, 2005. The data of focus group interview and faculty survey were analyzed by content analysis. frequency and percentile. Results : 66.7% of faculty have pointed out that it is right a direction of new curriculum but there are some problems in curriculum management. The most frequently addressed problem in the new curriculum is as follows : ability of self-directed learning(15.3%). deficiency of faculty understanding(10.5%). The faculty comments on the improvement areas of new curriculum such as curriculum revision (8.6%). efficiency of curriculum management (6.7%), reward and incentive system of education(6.7%). The focus groups pointed out the important factors of curriculum reformation such as horizontal and vertical integrity between subjects, improvement of student achievement test, enhancement of self-directed learning. responsibility and authorities of course director. Conclusions : It should be concluded. to succeed curriculum reformation, which the purpose of curriculum reformation announces obviously and management group should effort continuously so that professors may understand the new curriculum. The course directors have to responsibility and authorities operating the subjects and the university should develop the students' evaluation system and faculty performance appraisal system.