• Korean Journal of Construction Engineering and Management
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• v.23 no.3
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• pp.95-103
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• 2022

Recently, the fourth industrial revolution has a great influence on the development of many industries as well as the construction industry. Various technologies related to the industrial revolution 4.0, such as AI and big data, have gained much attention. However, little has been known about the importance and preparedness of stakeholders of the construction industry in Korea for the industry 4.0 technologies so far. This study revealed how the stakeholders perceive and prepare for industry 4.0 using a survey. In addition, collaboration potential score for each technology was calculated to find technologies with high potential for collaboration. Result is that the importance of the technologies was evaluated high in overall, but the preparedness and implementation in university education or business was evaluated low. Technologies with high potential for industry-university collaboration are AI/big data and 3D printing/3D scanning. This study can contribute to the training of industry 4.0 experts and improving preparedness, which would enable the innovation and application of industry 4.0 technologies in the construction industry.

• Asian Journal for Public Opinion Research
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• v.9 no.3
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• pp.240-265
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• 2021

Public services need to be evaluated regularly to identify areas that need further improvement. Data collection via Twitter is affordable and timely, so it has the potential to be utilized to evaluate the quality of public service. This study utilizes tweets mentioning three service units of the provincial government of Jakarta and applies both sentiment analysis and topic classification to predict a rating/score of public service quality. The research goal is to examine if the evaluation of public services based on social media data is possible. The findings indicate that the use of Twitter has an advantage in terms of sample size and variety of opinions. Tweets can be translated into scores as well. Nonetheless, the representativeness issue and the predominance of complaint tweets can affect the reliability of the results.

• Korean Journal of Ecology and Environment
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• v.50 no.4
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• pp.478-482
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• 2017

In order to identify key nations and bird species of conservation concern we described multinational collaborations as defined using network analysis linked by birds that are found in all nations in the network. We used network analysis to assess the patterns in bird occurrence for 10,422 bird inventories from 244 countries and territories. Nations that are important in multinational collaborations for bird conservation were assessed using the centrality measures, closeness and betweenness centrality. Countries important for the multinational collaboration of bird conservation were examined based on their centrality measures, which included closeness and betweenness centralities. Comparatively, the co-occurrence network was divided into four groups that reveal different biogeographical structures. A group with higher closeness centrality included countries in southern Africa and had the potential to affect species in many other countries. Birds in countries in Asia, Australia and the South Pacific that are important to the cohesiveness of the global network had a higher score of betweenness centrality. Countries that had higher numbers of bird species and more extensively distributed bird species had higher centrality scores; in these countries, birds may act as excellent indicators of trends in the co-occurrence bird network. For effective bird conservation in the world, much stronger coordination among countries is required. Bird co-occurrence patterns can provide a suitable and powerful framework for understanding the complexity of co-occurrence patterns and consequences for multinational collaborations on bird conservation.

• Molecules and Cells
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• v.39 no.2
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• pp.103-110
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• 2016

As a degenerative joint disease, osteoarthritis (OA) constitutes a major cause of disability that seriously affects the quality of life of a large population of people worldwide. However, effective treatment that can successfully reverse OA progression is lacking until now. The present study aimed to determine whether two small non-coding RNAs miR-29a and miR-140, which are significantly down-regulated in OA, can be applied together as potential therapeutic targets for OA treatment. MiRNA synergy score was used to screen the miRNA pairs that potentially synergistically regulate OA. An in vitro model of OA was established by treating murine chondrocytes with IL-$1{\beta}$. Transfection of miR-29a and miR-140 via plasmids was investigated on chondrocyte proliferation and expression of nine genes such as ADAMTS4, ADAMTS5, ACAN, COL2A1, COL10A1, MMP1, MMP3, MMP13 and TIMP metallopeptidase inhibitor 1 (TIMP1). Western blotting was used to determine the protein expression level of MMP13 and TIMP1, and ELISA was used to detect the content of type II collagen. Combined use of miR-29a and miR-140 successfully reversed the destructive effect of IL-$1{\beta}$ on chondrocyte proliferation, and notably affected the MMP13 and TIMP1 gene expression that regulates extracellular matrix. Although co-transfection of miR-29a and miR-140 did not show a synergistic effect on MMP13 protein expression and type II collagen release, but both of them can significantly suppress the protein abundance of MMP13 and restore the type II collagen release in IL-$1{\beta}$ treated chondrocytes. Compared with single miRNA transfection, cotransfection of both miRNAs exceedingly abrogated the suppressed the protein production of TIMP1 caused by IL-$1{\beta}$, thereby suggesting potent synergistic action. These results provided1novel insights into the important function of miRNAs' collaboration in OA pathological development. The reduced MMP13, and enhanced TIMP1 protein production and type II collagen release also implies that miR-29a and miR-140 combination treatment may be a possible treatment for OA.