• 한국건설관리학회논문집
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• 제23권3호
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• pp.95-103
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• 2022

4차산업혁명은 건설뿐만 아니라 많은 산업의 발전에 큰 영향을 미치고 있으며, 인공지능 및 빅데이터와 같은 4차산업혁명과 관련된 다양한 기술이 주목받고 있다. 하지만 4차산업혁명 기술에 대한 우리나라 건설산업 구성원들의 중요도 및 준비도와 같은 인식에 대해서 알려진 바는 부족하다. 본 연구는 우리나라 건설산업 구성원들이 4차산업혁명 기술들에 대해 어떻게 인식하고 준비하고 있는지 설문을 통해 파악하였다. 또한, 산업계와 학계의 협력가능점수를 바탕으로 협력 가능성이 높은 기술은 어떤 것이 있는지 제시하였다. 설문 결과 전체적으로 4차산업혁명 기술의 중요도는 높게 평가되었지만, 준비도 및 대학교육이나 사업에서의 활용 정도는 낮게 평가되었다. 또한, 산학협력 가능성이 높은 4차산업혁명 기술은 빅데이터/인공지능, 3D 프린팅/3D 스캐닝 순서로 높게 나타났다. 이를 바탕으로 4차산업혁명 전문인력 양성 및 준비도 향상에 도움이 될 수 있으며, 나아가 4차산업혁명 기술들을 건설산업에 적용시켜 혁신을 이루는데 기여할 것이다.

• Asian Journal for Public Opinion Research
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• 제9권3호
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• pp.240-265
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• 2021

Public services need to be evaluated regularly to identify areas that need further improvement. Data collection via Twitter is affordable and timely, so it has the potential to be utilized to evaluate the quality of public service. This study utilizes tweets mentioning three service units of the provincial government of Jakarta and applies both sentiment analysis and topic classification to predict a rating/score of public service quality. The research goal is to examine if the evaluation of public services based on social media data is possible. The findings indicate that the use of Twitter has an advantage in terms of sample size and variety of opinions. Tweets can be translated into scores as well. Nonetheless, the representativeness issue and the predominance of complaint tweets can affect the reliability of the results.

• 생태와환경
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• 제50권4호
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• pp.478-482
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• 2017

In order to identify key nations and bird species of conservation concern we described multinational collaborations as defined using network analysis linked by birds that are found in all nations in the network. We used network analysis to assess the patterns in bird occurrence for 10,422 bird inventories from 244 countries and territories. Nations that are important in multinational collaborations for bird conservation were assessed using the centrality measures, closeness and betweenness centrality. Countries important for the multinational collaboration of bird conservation were examined based on their centrality measures, which included closeness and betweenness centralities. Comparatively, the co-occurrence network was divided into four groups that reveal different biogeographical structures. A group with higher closeness centrality included countries in southern Africa and had the potential to affect species in many other countries. Birds in countries in Asia, Australia and the South Pacific that are important to the cohesiveness of the global network had a higher score of betweenness centrality. Countries that had higher numbers of bird species and more extensively distributed bird species had higher centrality scores; in these countries, birds may act as excellent indicators of trends in the co-occurrence bird network. For effective bird conservation in the world, much stronger coordination among countries is required. Bird co-occurrence patterns can provide a suitable and powerful framework for understanding the complexity of co-occurrence patterns and consequences for multinational collaborations on bird conservation.

• Molecules and Cells
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• 제39권2호
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• pp.103-110
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• 2016

As a degenerative joint disease, osteoarthritis (OA) constitutes a major cause of disability that seriously affects the quality of life of a large population of people worldwide. However, effective treatment that can successfully reverse OA progression is lacking until now. The present study aimed to determine whether two small non-coding RNAs miR-29a and miR-140, which are significantly down-regulated in OA, can be applied together as potential therapeutic targets for OA treatment. MiRNA synergy score was used to screen the miRNA pairs that potentially synergistically regulate OA. An in vitro model of OA was established by treating murine chondrocytes with IL-$1{\beta}$. Transfection of miR-29a and miR-140 via plasmids was investigated on chondrocyte proliferation and expression of nine genes such as ADAMTS4, ADAMTS5, ACAN, COL2A1, COL10A1, MMP1, MMP3, MMP13 and TIMP metallopeptidase inhibitor 1 (TIMP1). Western blotting was used to determine the protein expression level of MMP13 and TIMP1, and ELISA was used to detect the content of type II collagen. Combined use of miR-29a and miR-140 successfully reversed the destructive effect of IL-$1{\beta}$ on chondrocyte proliferation, and notably affected the MMP13 and TIMP1 gene expression that regulates extracellular matrix. Although co-transfection of miR-29a and miR-140 did not show a synergistic effect on MMP13 protein expression and type II collagen release, but both of them can significantly suppress the protein abundance of MMP13 and restore the type II collagen release in IL-$1{\beta}$ treated chondrocytes. Compared with single miRNA transfection, cotransfection of both miRNAs exceedingly abrogated the suppressed the protein production of TIMP1 caused by IL-$1{\beta}$, thereby suggesting potent synergistic action. These results provided1novel insights into the important function of miRNAs' collaboration in OA pathological development. The reduced MMP13, and enhanced TIMP1 protein production and type II collagen release also implies that miR-29a and miR-140 combination treatment may be a possible treatment for OA.