• 사상체질의학회지
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• 제27권1호
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• pp.42-56
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• 2015

Objectives This research was proposed to present Clinical Practice Guideline(CPG) for Taeeumin Disease of Sasang Constitutional Medicine(SCM): Esophagus Cold-based Exterior Cold (Wiwansuhan-pyohan) disease. This CPG was developed by the national-wide experts committee consisting of SCM professors. Methods First, collection and organization of literature related to SCM such as Donguisusebowon, Text book of SCM, Clinical Guidebook of SCM and Fundamental research to standardize diagnosis of Sasang Constitutional Medicine was performed. Secondly, journals related to clinical trial or Human complementary medicine of SCM were searched. Finally, 7 articles were selected and included in CPG for Esophagus Cold-based Exterior Cold (Wiwansuhan-pyohan) disease. Results & Conclusions The CPG of Esophagus Cold-based Exterior Cold (Wiwansuhan-pyohan) disease in Taeeumin Disease include classification, definition and standard symptoms of each pattern. Esophagus Cold-based Exterior Cold (Wiwansuhan-pyohan) disease consists of two aspects : Esophagus-Cold (Wiwanhan) and Esophagus-Cold Lung-Dry (Wiwanhan-paejo) symptomatology. Esophagus-Cold (Wiwanhan) symptomatology is classified into mild and moderate pattern by severity. Mild pattern of Esophagus-Cold (Wiwanhan) symptomatology is classified into Supraspinal Exterior (Baechu-pyo) initial and Wheezing-Dyspnea (Hyocheon) pattern. Moderate pattern of Esophagus-Cold (Wiwanhan) symptomatology is classified into Cold-reversal (Hanguel) and Cold-reversal (Hanguel) advanced pattern. And Esophagus-Cold Lung-Dry (Wiwanhan-paejo) symptomatology is classified into severe and critical pattern by severity. Severe pattern of Esophagus-Cold Lung-Dry (Wiwanhan-paejo) is classified into Dry-Cold (Johan) pattern and Dry-Cold (Johan) advanced pattern. Critical pattern of Esophagus-Cold Lung-Dry (Wiwanhan-paejo) symptomatology consists of Dry-Cold (Johan) intense pattern (Eumhyeol-mogal handa pattern).

• 대한한의학원전학회지
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• 제29권4호
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• pp.17-36
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• 2016

Objectives : This paper seeks to study the provenances of 10 Symptoms of Para-cold damage from Yixuerumen, and discovers the rationality and originality of para-cold damages recognized by Li Chan. Methods : The paper looks through the books referenced by Yixuerumen to investigate the source text for Yixuerumen's Para-cold Damage chapter, and the contents of the referenced books will be compared to that of Yixuerumen. Results : The sources of the 10 symptoms of para-cold damage from Yixuerumen Chapter of Cold Damage can be traced to Leizhenghuorenshu (expectoration, indigestion, rising temperature due to lack of energy, and beriberi), Wang Zhen's Shanghanzhengzhimingtiao Xinzengxuleishanghansizheng(the infection in a boil, blood sattis, caused overexertion, and pox), and Liu Chun's Yujiweiyi's chapter on Common Cold. Here, Li Chan made his own addition of internal damage and damage of overworking. Li Chan seems to have considered para-cold damage not as a type of cold damage but as a "concept relative to the broader range of cold damage." In reflection of this understanding, Li Chan limited the number of categories to ten in accordance with the developmental trace leading from Leizhenghuorenshu to Shanghanzhengzhimingtiao. When we understand para-cold damage as a "concept relative to the narrower range of cold damage," it could be used as a mean as for "Wenbin diagnosis," but Yixuerumen's para-cold damage is only utilized for the "diagnosis of a broader concept of cold damage." Conclusions : Li Chan deserves credits for his academic rationality and originality displayed by the method he used to form para-cold damages where he used real cold damage and para-cold damage as principles, by the division of para-cold damage symptoms into ten provenances, by the creation of the concept of para-cold damage, and by his broad collection of prescription and treatment corresponding to each type.

• 수산경영론집
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• 제37권2호
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• pp.111-139
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• 2006

Cold storage warehouse industry in Japan has been extended in its scale in terms of both the number of storages and cold storage capacity in order to meet the extended reproduction of the marine products industry. However, increasing total amount of the stored goods since mid 80s led to relative decrease of marine products while the number of storages was remained the same or decreased, though cold storage capacity was gradually increased and is maintained the increase of the average cold storage capacity. As structural change in the cold storage warehouse industry emerges, cold storage warehouses require new approach to individual storage management with 1)diversity of the stored goods; 2) more competition due to increase of the cold storage capacity; and 3) sizing of the average cold storage capacity. Therefore, this study analyzed how cold storage warehouse management activity with individual storage sizing changes; and significance of sizing and functional change in cold storage warehouses experiencing sizing, by observing leading cold storage warehouse industry of the metropolitan area in Japan. In conclusion, reorganization of cold storage warehouse industry in the metropolitan area in Japan can be summarized as follows: First, competition among cold storage warehouses in the metropolitan area in Japan is not simply limited to storage industry but extended to establishment and securing physical distribution function. Second, since cold storage warehouse industry is in Scrap & Build phase, decision of management executives on whether taking direction to maintain/continue enhancement of physical distribution function may cause drastic reorganization in the cold storage warehouse industry, Third, since profit of physical distribution management based on cold storage warehouses is insignificant, it is not easy to accomplish expected management outcome, Fourth, today's cold storage warehouse industry mainly characterized by diversity of the stored goods needs facility reorganization with comprehensive and functional integration covering from F class cold storage capacity to F&C class.

• 대한한의학원전학회지
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• 제31권1호
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• pp.1-14
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• 2018

Objectives : This paper reviews the possibility of confusing wind-cold and cold dryness that can be found in the critical discussion revolving Wu Jutong's concept of cold dryness. With this, the paper aims to refresh the understanding of the concept of cold dryness as put together by Wu Jutong. Methods : The paper reviews the concept of Wu Jutong's cold dryness based on today's critical discussions on the topic. At the same time, the paper searches for additional theoretical basis that can be proposed with regards to Wu Jutong's concept of cold dryness. Results : The core element of the criticisms against Wu Jutong's cold dryness is that cold dryness's cold dryness pattern proposes cold fluid as one of the main symptoms, and that Xiaoqinglongtang is referred to as a cure. However, the problem of the dryness and dampness that can be found in Wu Jutong's cold dryness seems that it can be explained by the discussions regarding Shenkuzao as written in Neijing. Moreover, considering the fact that the connection between cold paathogen and Shenkuzao that surfaced in historical medical theories can also be applied to the concept of cold dryness, it seems that it can be helpful in understanding the characteristics of disease mechanism of cold dryness. Conclusions : The discussion on the concept of cold dryness originally derives as a branch of the discussion on cold. Acknowledging this, it seems that reconsideration is required on the assertion that Wu Jutong confused the symptoms of wind-cold with that of cold dryness.

• 동의생리병리학회지
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• 제22권6호
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• pp.1410-1415
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• 2008

Acupuncture and herbal treatment are based on diagnosis of cold and heat pattern in Traditional Korean Medicine. This diagnosis is accomplished through pulse, tongue and question examination, which are not objective. Quantification and objectification of this diagnosis process are required for efficacious treatment and traditional medicine development. In this study, we developed the cold-heat pattern questionnaire for this purpose. Seventy nine patients who visited oriental medical hospital were included in this study. The cold-heat pattern questionnaire was composed of many questions about patient's physical condition, which were derived from The Traditional Oriental Medical Literature with Delphi Technique. Patients filled out the cold-heat pattern questionnaire by themselves. Diagnosis of cold and heat pattern are conducted separately by oriental medical doctors with more than 5 years' clinical experience. Various physical condition factors were derived for the cold-heat pattern questionnaire. (Preference temperature, Body temperature, Pain type, Face color, Urine, Stool and secretion features) Each cold and heat symptoms group acquired internal consistency. (Cronbach's ${\alpha}$ : Cold - 0.605, Heat - 0.722) There were significant associations between doctor's diagnosis and cold symptoms in 'Aversion to cold', 'Desire for heat', 'Pale face', 'Loose stools'. (p-value < 0.05) There were significant associations between doctor's diagnosis and heat symptoms in 'Desire for cold', 'Body feverishness', 'Thirst'. (p-value < 0.05) The internal consistency results suggest that the cold-heat pattern questionnaire assured reliability. Besides, these results showed that cold-heat symptoms are apt to appear together with, and this can be indirect evidence that diagnosis of cold-heat pattern is valuable for comprehension about disease pattern. Moreover, respective symptoms of cold-heat pattern showed different significance with doctor's diagnosis. Consequently these significant symptoms can be more considered for comprehension of cold-heat pattern.

• 동의생리병리학회지
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• 제19권5호
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• pp.1191-1194
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• 2005

The aim of this study was to investigate the change of Heart Rate Variability(HRV) that mild cold stimulus on the forehead of healthy men induces. 34 healthy male subjects participated in the experiments. On the first test series, 15 subjects were applied to the mild cold stimulus by the devise for cold stimulation. In the second test series, 10 subjects With heat Syndrome and 5 subjects With cold Syndrome were applied to the mild cold Stimulus. Aa a additional test, 4 subjects with cold syndrome were applied to the warm stimulus in the last test series. We analyzed the HRV through measuring electrocardiogram.(ECG). The result of this study is comparatively clear. In the first test series, mild cold stimulus made parasympathetic nervous system be activated. In the second test series, mild cold stimulus made parasympathetic nervous system be activated both in subjects with heat syndrome and subjects with cold syndrome, and heat syndrome shows more active parasympathetic nervous system rather than cold syndrome subjects do. In the last test series, 2 subjects with cold syndrome respond the mild cold stimulus. That means warm stimulus of cold condition subjects made parasympathetic nervous system active in 2 of 4 subjects. We found out that mild cold stimulus on forehead makes parasympathetic nervous system be activated in healthy male, and it can be interpreted that mild cold stimulus make healthy human be relaxed. Also, subjects have different fondness of thermal stimulus according to their Cold or Heat condition Preferences. Last test series shows that we need to investigate effect of the warm stimulus heat syndrome subjects.

• 한국컴퓨터정보학회논문지
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• 제21권2호
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• pp.1-7
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• 2016

In this paper, we propose in this paper present a novel locality data allocation policy as COLD(Correlated Locality Data) allocation policy. COLD is defined as a set of data that will be updated together later. By distributing a COLD into a NAND block separately, it can preserve th locality. In addition, by handling multiple COLD simultaneously, it can obtain the parallelism among NAND chips. We perform two experiment to demonstrate the effectiveness of the COLD data allocation policy. First, we implement COLD detector, and then, analyze a well-known workload. And we confirm the amount of COLD found depending on the size of data constituting the COLD. Secondly, we compared the traditional page-level mapping policy and COLD for garbage collection overhead in actual development board Cosmos OpenSSD. Experimental results have shown that COLD data allocation policy is significantly reduces the garbage collection overhead. Also, we confirmed that garbage collection overhead vary depending on the COLD size.

• 기본간호학회지
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• 제6권3호
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• pp.452-463
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• 1999

This study was performed to inquire into recognition of cold and heat application. The subjects in the study were 429 adults who were collected by disproportional quota sampling according to age, sex. The instrument was 36 questions that constitured closed questions and semiopened questions that encluded general characteristics, recognition of cold and heat applications. and what will you do when requested cold and heat applications on abdomial and perineal areas. Data were collected from september 25 to October 25, 1998. Data was analysed by SPSS/win, into frequency, Pearson correlation, t-test, ANOVA. The results were following. 1) The subjects consisted of male and female who was from teenage to fifty year old above. According to general characteristics, who endureed moderate cold-heat application, had constitutional fever, good sweat, and taked a cold bath accationally. And the woman think that their body were more cold than man. and the number of cold bath was less than man. Woman felt more harder than man that endured exposing cold. According to the recognitions of cold-heat applications, the 61.9% of the subjects think that cold application is more positive, and the 61.7% of the subjects think that heat application is more positive. 2) The subjects think that oral cavity, abdomen, back, extremes must be warm. 3) The percents of cold or heat application at abdomen were 77.4%, 86.5% respectely and the percents of cold or heat application at perineum were 56.9%. 93.6% respectely. With the above results. we know that the subjects have the fixed perceptions that each body part has to maintain its temperature. especially, they think that postpartum care is correlated with cold-heat application. So when we intervent nursing care, we also must regard their recognitions of cold and heat applications. and we need to educate and explain correctly about cold-heat application.

• 대한한의학방제학회지
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• 제24권1호
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• pp.31-43
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• 2016

Objectives Based on related literature, cold and heat, deficiency and excess, true and false, and actually used formulas, paradoxical treatments presented in the 『Plain Questions of Inner Canon of Yellow Emperor』 including ‘treating pseudo-heat symptoms and real cold syndrome with cold herbs, treating pseudo-heat symptoms and real cold syndrome with cold herbs’ were analyzed.Methods Out of literature, paradoxical treatment related classics and papers were investigated and analyzed. Among diseases and syndromes, real cold syndrome with pseudo-heat symptoms, real heat syndrome with pseudo-cold symptoms, real deficiency syndrome with pseudo-excess symptoms, and real excess syndrome with pseudo-deficiency symptoms were reviewed. Among formulas, typical examples of the above mentioned paradoxical treatments were used as examples to analyze paradoxical treatments.Results Treating pseudo-heat symptoms and real cold syndrome with cold herbs is a method that uses herbs with cool and cold nature to treat real cold syndrome with pseudo-heat symptoms and Tongmaeksayeokgajeodamjeuptang is suitable for this method. Treating pseudo-cold symptoms and real heat syndrome with hot herbs is a method that uses herbs with warm and hot nature to treat real heat syndrome with pseudo-cold symptoms and Baekhogainsamtang is suitable for this method.Conclusions Based on the related literature, cold and heat, deficiency and excess, true and false, and actually used formulas examined as mentioned above, the paradoxical treatments presented in the 『Plain Questions of Inner Canon of Yellow Emperor』 are thought to be reasonable paradoxical treatments that fit the diseases and syndromes that actually appeared in our bodies.

• 대한한방부인과학회지
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• 제18권4호
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• pp.85-105
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• 2005

Purpose : Investigate the effects of Chungganhaewooltang(CHT) on immobilization-stress or cold-stress in C576BL/6J mice. Methods : Male C57BL/6J 30 mice of weighting 18${\pm}$2g, were divided into sixs groups including the immobilization-stress group(5heads), after immobilization-stress CHT oral administration(500mg/kg) groups(5heads), cold-stress group(5heads) and after cold-stress CHT oral administration(500mg/kg) groups(5heads). then we observed changes in the serum histamine and corticosterone level and changes immune system Results : Immobilization-stress or cold-stress increased the serum level of histamine and corticosterone. CHT decreased the serum level of histamine and corticosterone increased by cold-stress. CHT inhibited the release of histamine from mast cells at the concentration of 0.1 mg/ml. In addition, immobilization-stress or cold-stress decreased the cell viability of murine thymocytes and splenocytes. CHT increased the cell viability of thymocytes decreased by immobilization-stress or cold-stress, but did not affect the cell viability of splenocytes decreased by immobilization-stress or cold-stress. Also immobilization-stress or cold-stress increased DNA fragmentation of thymocytes and splenocytes. CHT decreased DNA fragmentation of thymocytes increased by immobilization-stress or cold-stress, but did not affect DNA fragmentation of splenocytes increased by immobilization-stress or cold-stress. Immobilization-stress increased the population of thymic $CD4^+$ cells. CHT decreased the population of thymic $CD4^+$ cells increased by immobolization-stress. Immobilization-stress or cold-stress decreased the population of $B220^+$ cells and increased the population of $thy1^+$ cells. CHT decreased the population of $thy1^+$ cells increased by immobilization-stress or cold-stress. Immobilization-stress or cold-stress increased the population of splenic $CD4^+$ cells and $CD8^+$ cells. CHT decreased the population of splenic $CD4^+$ cells increased by immobolization-stress or cold-stress. Immobilization-stress or cold-stress decreased the production of ${\gamma}-interferon$(IFN) interleukin(IL)-2 and IL-4. CHT enhanced the production of ${\gamma}-IFN$ decreased by immobilization-stress or cold-stress but did not affect the production of IL-2 and IL-4 decreased by immobilization-stress or cold-stress. Furthermore, Immobilization- stress or cold-stress decreased the phagocytic activity of peritoneal macrophages and the production of nitric oxide. CHT enhanced the phagocytic activity and nitric oxide production decreased by cold-stress. Conclusion : CHT may be useful for the prevention and treatment of stress via suppression of serum histamine and corticosterone level and enhancement of immune response.