• Health Policy and Management
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• v.25 no.4
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• pp.253-255
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• 2015

The concept of precision medicine-prevention and treatment strategies that take individual variability into account-is hot issue of US in the year 2015. Precision medicine is a new concept that approach patients individually by there characteristics, such as genome, life style, environmental exposure, etc. For developing the precision medicine, National Institute of Health of US has been prepared the Precision Medicine Initiative Cohort Program, at least 1 million people cohort. The US President Obama announced the Precision Medicine Initiative on 30th January 2015. He announced that he will pioneer a new model of patient-powered research that promises to accelerate biomedical discoveries and provide clinicians with new tools, knowledge, and therapies to select which treatments will work best for which patients. Most medical treatments have been designed for the 'average patient.' As a result of this 'one-size-fits-all-approach,' treatments can be very successful for some patients but not for others. This is changing with the emergence of precision medicine, an innovative approach to disease prevention and treatment that takes into account individual differences in people's genes, environments, and lifestyles. Precision medicine gives clinicians tools to better understand the complex mechanisms underlying a patient's health, disease, or condition, and to better predict which treatments will be most effective. The healthcare researcher should prepare the new medicine era such as bio-information technology convergence, big data study.

• Journal of the Korean Society of Food Culture
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• v.17 no.4
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• pp.435-445
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• 2002

The purpose of this study was to identify the pattern and perception of food consumption, mass restaurant use, drinking style, and food purchasing factors by cohort groups i. e., World Cup(W) generation, baby boom, and silent generation. Data were collected from 412 respondents including three generations by questionnaire method in April through May 2002. Analysis of variance and chi-square results indicate that there were significant differences among three generation groups for the pattern and perception of food consumption, the use of mass restaurant, preferred drinking style, and influencing factors for food purchasing. W generation are more likely to be influenced by sensibility factor than baby boom and silent generation. Considering food preference pattern, baby boom as well as silent generation prefer green vegetables than meats, and they must have Kimche when having meals. Similarities and differences in perceptional pattern types are discussed, and future implications for food and nutrition specialists and food marketers are provided.

• Journal of the Korean housing association
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• v.22 no.1
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• pp.11-23
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• 2011

The purpose of this study is to explore cohort changes in first-time homeownership in Korea. The study collected qualitative data from individual interviews to explore the housing trajectories of different birth cohorts. As a result, Individual interviews facilitated an exploration of the decision making process of first-time homeowner with in a cohort context. The cohorts born in the 1950s seek a sense of security through homeownership, and have strong Korean sentiments of ownership. They tried various means to buy a house, and real estate market boom at that time played a role in the driving force. The cohorts born in the 1960s have less insecurity of tenure than the previous cohorts, but they still feel the need for homeownership. Since the currency crisis in 1997 caused the fluctuation of housing price, the 1960s cohort experienced a dramatic decline and rebound of assets while the previous cohorts had experienced a steady rise in housing prices. Finally, the attitude towards housing in the group of 1970s cohorts has changed from ownershiporiented to use-oriented.

• Child Health Nursing Research
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• v.17 no.4
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• pp.281-287
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• 2011

Purpose: The study was done to explore growth variation in head circumference (HC) in extremely premature infants (EPI) with brain injury. Methods: A retrospective cohort study was conducted with 79 cohort samples from the archives of the catch-up growth project. Mean age of the infants was 29.2 weeks of gestation and mean HC, 27.1 cm at birth. Their HC measurements were retrieved from the archives up to 6 month of corrected age (CA) and analyzed against history of brain injury during hospitalization. Results: Overall growth retardation in HC was observed in the cohort sample compared to longer gestation premature infants. EPI with brain injury showed decreased HC compared to infants without brain injury, and resulting growth variation across 6 month of CA. Highest retardation in HC growth was observed in male infants with brain injury. Conclusion: Extreme preterm birth itself may function as a major obstacle against HC growth toward term age in EPI. Sustainability of brain injury could be observed with higher HC growth retardation after term. Evolutionary favor to female infants may exist in HC growth of EPI. Intensive education on HC monitoring is highly suggested for parents of EPI, particularly with children with brain injury.

• Journal of the Korean Home Economics Association
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• v.49 no.4
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• pp.67-76
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• 2011

This study had two goals: 1) to explore generational differences in traditional family rituals and 2) to investigate the association between family values and family rituals. Using survey data from 500 married men and women in their 20s to 60s, we classified three generations: 1) 1941-1950 birth cohort (aged 59-68), 2) 1951-1970 birth cohort (aged 39-58), and 3) 1971 and later cohort (aged 38 or less). These generations represented post-colonialism, modernization, and the information era in Korea, respectively. The results demonstrated that birth-related traditional family rituals had been maintained across the generations. Ancestor worship was less likely to be observed by later generations. Further, the way in which family values was associated with family rituals differed across the generations, indicating that traditional family values had different influences on everyday family life culture across generations.

• Journal of the Korean Society of Food Culture
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• v.35 no.3
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• pp.311-322
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• 2020

Recently, there is growing interest in studying the dietary patterns that affect the risk of circulatory system diseases (CSDs). We investigated the relationship between CSDs and dietary patterns through a follow-up study in Korea (2001-2016). The participants of this study were obtained from the Korean Genome and Epidemiology Study (KoGES). This study was a large community-based cohort study (the Ansan-Ansung areas) conducted to assess the effects of various factors, especially diet, on the onset of chronic diseases among the Korean population aged 40-69 yrs. Baseline data were collected from 2001 to 2002, and follow-up studies were performed every 2 yrs, with over 7 follow-up studies performed (2015-2016). Three dietary patterns were identified using factor analysis: "vegetable and seafood (men)/soup and stew (women)" pattern, "sweet foods and breads-rice cake" pattern, and "multigrain rice and cooked white rice" pattern. None of the dietary patterns were significantly associated with the risk of CSDs in either men or women. Our follow-up study is meaningful as it investigated whether the dietary patterns of individuals according to sex affects the development of CSDs.

• Journal of Korean Society for Atmospheric Environment
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• v.25 no.4
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• pp.339-346
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• 2009

The objectives of this study were to introduce spatial interpolation methods which have been applied in recent papers, to apply three methods (nearest monitor, inverse distance weighting, kriging) to domestic data (Ulsan cohort) as an example of estimating the personal exposure levels. We predicted the personal exposure estimates of 2,102 participants in Ulsan cohort using spatial interpolation methods based on information of their residential address. We found that there was a similar tendency among the estimates of each method. The correlation coefficients between predictions from pairs of interpolation methods (except for the correlation coefficient between nearest montitor and kriging of CO and $SO_2$) were generally high (r=0.84 to 0.96). Even if there are some limitations such as location and density of monitoring station, spatial interpolation methods can reflect spatial aspects of air pollutant and spatial heterogeneity in individual level so that they provide more accurate estimates than monitor data alone. But they may still result in misclassification of exposure. To minimize misclassification for better estimates, we need to consider individual characteristics such as daily activity pattern.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.9
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• pp.5153-5155
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• 2013

Background: Because of the gender disparity in the incidence of thyroid cancer, this study aimed to determine the association between reproductive factors and thyroid cancer. Methods: A total of 10,767 eligible women from the Khon Kaen Cohort, recruited and interviewed between 1990 and 2001, were followed up until 2011. The data were linked to the Khon Kaen Population-Based Cancer Registry to detect thyroid cancer cases. Results: There was 17 thyroid cancer cases detected, an incidence of 11.2 per 100,000 person-years, of which 70.6 % were papillary tumors. The incidence was apparently greater among those with an early age of menarche, nulligravida women, and oral contraceptive users. Conlusions: There was a trend for thyroid cancer to develop in relation to longer estrogen exposure. This evidence is inconclusive but warrants further investigation.

• Journal of Ginseng Research
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• v.27 no.4
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• pp.158-164
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• 2003

Recently, there are much concerns about ginseng as disease therapeutics. There are no epidemiologic study on relationship between ginseng intake and all cause mortality based from general population Cohort. This study sought to examine relationships between ginseng intake and all cause mortality from Kangwha Cohort data. From March 1985 through December 1999, 2696 males and 3595 females who were aged 55 or over as of 1985 were followed up. We calculate the mortality rate, standardized mortality ratio and risk ratios by ginseng intake. Cox proportional hazard model was used to adjust various confounding factors. Ginseng intake group had the lower all cause mortality(Risk ratio(RR)=0.88, 95%Confidence Interval(CI)=0.79-0.97) among males. Increasing ginseng intake, lower all cause mortality(Low ginseng intake: RR=0.88, 95%CI=0.79-0.98; high ginseng intake : RR=0.87, 95%CI=0.75-1.00) among males. There is no statistically significant difference between ginseng intake and mortality among females. The results of this study suggests that ginseng intake may prolong the human life among males.

• Journal of the Korean Society of Food Culture
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• v.19 no.1
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• pp.118-127
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• 2004

The purpose of this study was to identify the preferred types and consumption patterns of food away from home by socio-demographic factors including cohort groups, sex. and consumption patterns consisting of 6 types. Data were collected from 412 respondents by questionnaire method in April through May 2002. Regression results indicate that sex, age, family income, family type and size as well as the consumption patterns were significant in explaining the determinants of food away from home expenditures. Four logit function (each for Korean, American, Japanese, and bunsik) results showed that each type of food away from home was likely to vary depending on socio-demographic factors (i.e., cohort groups and sex) and the consumption patterns (i.e., convenience and simple, distinction and variety, tradition oriented, foreign design, health and quality oriented, sensible taste and mood). Similarities and differences in food away from home types are discussed, and future implications for food and nutrition specialists as well as food industrial marketers are provided.