• Title/Summary/Keyword: Co-exposure

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Ambient Levels of CO and PM10 at Low- and High-floor Apartments in Industrial Complexes (산업단지 내 저층과 고층 아파트의 외기 중 호흡성분진과 일산화탄소 수준)

  • Jo, Wan-Kuen;Lee, Joon-Yeob
    • Journal of Environmental Science International
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    • v.15 no.8
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    • pp.719-725
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    • 2006
  • Since low-floor apartments ate vertically closer to patting lots and roadways, it is hypothesized that residents in low-floor apartments may be exposed to elevated ambient levels of motet vehicle emissions compared to residents in high-floor apartments. The present study examined this hypothesis by measuring two motor vehicle source-related pollutants(CO and PM10) in ambient air of high-rise apartment buildings within the boundary of industrial complexes according to atmospheric stability The ambient air concentrations of CO and PM10 were higher for low-floor apartments than for high-floor apartments, regardless of atmospheric stability, The median concentration ratio of the low-floor air to high-floor alt ranged from 1.3 to 2.0, depending upon atmospheric stabilities, seasons and compounds. Moreover, the CO and PM10 concentrations were significantly higher in the winter and in the summer, regardless of the Hoot height. Atmospheric stability also was suggested to be important for the residents' exposure of high-rise apartment buildings to both CO and PM10. The median ratios of surface inversion air to non-surface inversion air ranged from 1.2 to 1.7 and from 1.0 to 1.6 lot PM10 and CO, respectively, depending upon seasons. Conclusively, these parameters(apartment floor height, season, and atmospheric stability) should be considered when evaluating the exposure of residents, living in high-rise apartment buildings, to CO and PM10. Meanwhile, the median PMl0 outdoor concentrations were close to or higher than the Korean annual standards for PM10, and the maximum PM10 concentrations substantially exceeded the Korean PM10 standard, thus suggesting the need for a management strategy for ambient PM 10. Neither the median nor the maximum outdoor CO concentrations, however, were higher than the Korean CO standard.

Mobi-Kids Study: Exposure Assessment of Electromagnetic Radiation from Mobile Phones I. Analysis on Exposure Types (Mobi-Kids Study: 휴대전화의 전자파 노출량 평가 I. 노출 유형 분석)

  • Lee, Ae-Kyoung;Wi, Hyunho;Yoon, Yonghyun;Kim, Dae-Keon;So, Jae-Sang;Lee, Byungje;Choi, Hyung-Do
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.24 no.10
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    • pp.1017-1026
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    • 2013
  • Four countries are participating in exposure assessment for Mobi-Kids Study. Each country evaluates RF and ELF exposure from mobile phones considering telecommunication system and environment in the corresponding area. The results will be used to determine accumulation exposure level of each subject in case and control groups to assess the potential carcinogenic effects of childhood and adolescent exposure to radio frequency(RF) and extremely low frequency( ELF) from mobile phones on the central nervous system. This paper analyzes exposure types of mobile phones which have been used in Korea for about 10 years, based on Mobi-Kids protocol. It includes investigation of mobile phone models released in the domestic market, design of numerical phone models to represent each exposure type, and measurement of ELF radiation from mobile phones.

New evidences of neurotoxicity of aroclor 1254 in mice brain: potential of coenzyme q10 in abating the detrimental outcomes

  • Majumdar, Anuradha;Nirwane, Abhijit;Kamble, Rahul
    • Environmental Analysis Health and Toxicology
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    • v.29
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    • pp.1.1-1.7
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    • 2014
  • Objectives The present subacute study was designed to evaluate the effect of coenzyme Q 10 (CoQ10) in the 28 days aroclor 1254 exposure induced oxidative stress in mice brain. Methods Biochemical estimations of brain lipid peroxidation (LPO), reduced glutathione (GSH), and activities of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) and acetyl cholinesterase (AChE), and histopathological investigations of brain tissue were carried out. Results Oral exposure of aroclor 1254 (5 mg/kg) led to significant decrease in levels of GSH, and activities of SOD, CAT, GPx, and AChE, and increase in LPO. These aberrations were restored by CoQ10 (10 mg/kg, intraperitoneal injection [IP]). This protection offered was comparable to that of L-deprenyl (1 mg/kg, IP) which served as a reference standard. Conclusions Aroclor 1254 exposure hampers the activities of various antioxidant enzymes and induces oxidative stress in the brains of Swiss albino mice. Supplementation of CoQ10 abrogates these deleterious effects of aroclor 1254. CoQ10 also apparently enhanced acetyl cholinesterase activity which reflects its influence on the cholinergic system.

Administrative dose control for occupationally-exposed workers in Korean nuclear power plants

  • Kong, Tae Young;Kim, Si Young;Jung, Yoonhee;Kim, Jeong Mi;Cho, Moonhyung
    • Nuclear Engineering and Technology
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    • v.53 no.1
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    • pp.351-356
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    • 2021
  • Korean nuclear power plants (NPPs) have various radiation protection programs to attain radiation exposure as low as reasonably achievable (ALARA). In terms of ALARA, this paper provides a comprehensive overview of administrative dose control for occupationally-exposed workers in Korean NPPs. In addition to dose limits, administrative dose constraints are implemented to resolve an inequity of radiation exposure in which some individuals in NPPs receive relatively higher doses than others. Occupational dose constraints in Korean NPPs are presented in this paper with the background of how those values were determined. For pressurized water reactors, 80% and 90% of the annual average limit for an effective dose, 20 mSv/y, are set as the primary and secondary dose constraints, respectively. Pressurized heavy water reactors (PHWRs) have also established the primary and secondary dose constraints corresponding to 70% and 80% of the effective dose limit, and additional constraints for tritium concentration are provided to control internal exposure in PHWRs. Follow-up measures for exceeding these administrative dose constraints are also introduced compared to exceeding the dose limits. Finally, analysis results of dose distributions show how the implementation of administrative dose constraints impacted the occupational dose distributions in Korean NPPs during the years 2009-2018.

Effect of Carbon Dioxide Concentration on Malate and Titratable Acidity in Pereskia aculeata and Kalanchoe rosea

  • Park Shin Young;Furukawa Akio
    • Environmental Sciences Bulletin of The Korean Environmental Sciences Society
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    • v.2 no.2
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    • pp.109-114
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    • 1998
  • The induction of crassulacean acid metabolism(CAM) characterized by day/night acid fluctuation was investigated in leaves from 10 days exposure to elevated $CO_2$ concentration(1,000 ${\mu}L\;L^{-1}CO_2).$ For Pereskia aculeata, have $C_3-like$ gas exchange pattern in well watered condition and shift into CAM-like in water stress, showed a more typical CAM-like diurnal acid fluctuation. Whereas the massive diurnal fluctuation of acidity in typical CAM of Kalanchoe rosea was declined. The effect of short-term exposure to various concentrations of $CO_2$ on titratable acidity in P. aculeata and K. rosea was also investigated. To investigate the response of various $CO_2$ concentrations, four different $CO_2$ levels(350, 700, 1,000 and 1,500 ${\mu}L\;L^{-1})$ were imposed for 24hr and measured the titratable acidity at 06:00, when the acidity was maximum, and 14:00, when the acidity was minimum. The accumulation of acid in P. aculeata was enhanced markedly by higher concentration of $CO_2,$ while the level of acidity in f rosea did not highly respond to $CO_2.$ A notable difference between P. aculeata and K. rosea was the response of de-acidification to a higher concentration of $CO_2$ Increasing with $CO_2,$ the degree of do-acidification of P. auleata was increased while that of K. rosea was depressed.

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Exposure to PM10 and Carbon Monoxide (CO) Associated with Automobile Travels (자동차 운행과 관련한 PM10 및 일산화탄소 노출 평가)

  • 조완근;이진우
    • Journal of Korean Society for Atmospheric Environment
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    • v.17 no.4
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    • pp.321-329
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    • 2001
  • This study included three experiments to evaluate in-vehicle exposures to PM10 and CO: 1) evaluation of in-passenger car exposures, 2) evaluation of in-public bus exposures, and 3) simultaneous evaluation of in-passenger car and in -university bus exposures. The tests of four factors (transportation mode, passenger-car type, commute period, and commute season were focused. A total of 40 actual passenger car commuters, 20 public bus commuters, and four university buses were recruited or surveyed. The same commuters ware participated in both the summer and winter studied. Two factory such as transportation mode and passenger-car type were found to have little effect on the in-vehicle levels of PM10 and CO. Commute period was found to have little effect on the in-vehicle CO levels. Conversely, the other factor, commuting season was found to influence on the in-vehicle levels of PM10 and CO. The present study also confirmed that under the Korean commute conditions, vehicle interiors are an important microenvironment for exposure to PM10 and CO. This was supported by finding that the in-vehicle Air levels were much higher than ambient air levels reported by several previous studies. The mean in -vehicle PM10 concentrations were 114 and 103$\mu\textrm{g}$/m$^3$for passenger cars and public buses, respectively. For CO, the mean in-vehicle concentrations were 2.9 and 2.6 ppm for passenger cars and public louses, respectively.

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Gene Expression Analysis of Rat Liver Epithelial Cells in Response to Thioacetamide

  • Park, Joon-Suk;Yeom, Hye-Jung;Jung, Jin-Wook;Hwang, Seung-Yong;Lee, Yong-Soon;Kang, Kyung-Sun
    • Molecular & Cellular Toxicology
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    • v.1 no.3
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    • pp.203-208
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    • 2005
  • Thioacetamide (TA) is potent haptotoxincant that requires metabolic activation by mixed-function oxidases. Micrcarray technology, which is massive parallel gene expression profiling in a single hybridization experiment, has provided as a powerful molecular genetic tool for biological system related toxicant. In this study we focus on the use of toxicogenomics for the determination of gene expression analysis associated with hepatotoxicity in rat liver epithelial cell line WB-F344 (WB). The WB cells was used to assess the toxic effects of TA. WB cells were exposed to two concentrations of TA-doses which caused 20% and 50% cell death were chosen and the cells exposed for periods of 2 and 24 h. Our data revealed that following the 2-h exposure at the both of doses and 24-h exposure at the low doses, few changes in gene expression were detected. However, after 24-h exposure of the cells to the high concentration, multiple changes in gene expression were observed. TA treatment gave rise predominantly to up-regulation of genes involved in cell cycle and cell death, but down-regulation of genes involves in cell adhesion and calcium ion binding. Exposure of WB cells to higher doses of the TA gave rise to more changes in gene expression at lower exposure times. These results show that TA regulates expression of numerous genes via direct molecular signaling mechanisms in liver cells.

An Investigation of Consumer Product Co-use Patterns - Focusing on air-fresheners and deodorizer - (생활화학제품 동시 사용현황 조사 - 방향제와 탈취제를 중심으로 -)

  • Lee, Daeyeop;Lim, Hyunwoo;Kim, Joo-Hyon;Kim, Taksoo;Hwang, Moonyoung;Seok, Kwangseol;Seo, Jungkwan
    • Journal of Environmental Health Sciences
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    • v.44 no.3
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    • pp.275-282
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    • 2018
  • Objective: Since certain chemicals are widely applied in a variety of consumer products, exposure via simultaneous use of multiple consumer products can put human health at risk. For this reason, use patterns of consumer products are an important factor inhuman health risk assessment. The aim of this study is to investigate co-use patterns of air-fresheners and deodorizers in Korea in order to estimate potential cumulative exposure. Methods: To collect the information on use patterns of air-fresheners and deodorizers, ten air-fresheners and 14 deodorizers were selected. A total of 3,000 participants were recruited and asked through on line questionnaires whether they had simultaneously used the selected air-fresheners and deodorant products in their daily lives. Results: Among the 3,000 participants, 45.6% had used more than two air fresheners and 46.3% used more than two deodorizers. The most common types of air fresheners used concurrently include liquid and candle types for indoor environments, while those of deodorizers were fabric trigger sprays and refrigerator gels. In addition, 73.7% used more than two products without product categories. Fabric trigger sprays were contained in all of the high-ranking product combinations. Conclusions: This study showed that many consumers concurrently used air-fresheners and deodorizers in their daily routines. For accurate exposure assessment, co-use patterns of consumer products should be further investigated.