• 제목/요약/키워드: Co-exposure

검색결과 979건 처리시간 0.03초

Ecophysiological responses of Quercus gilva, endangered species and Q. glauca to long-term exposure to elevated CO2 concentration and temperature

  • Kim, Hae-Ran;You, Young-Han
    • Journal of Ecology and Environment
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    • 제35권3호
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    • pp.203-212
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    • 2012
  • The physiological effects of elevated $CO_2$ concentration and temperature were examined for Quercus gilva and Q. glauca grown under control (ambient $CO_2$ and temperature) and treatment (elevated $CO_2$ and temperature) conditions for 39 months. The objective of the study was to measure the long-term responses, in physiological parameters, of two oaks species exposed to elevated $CO_2$ and temperature. The photosynthetic rate of Q. gilva was found to be decreased, but that of Q. glauca was not significantly affected, after long-term exposure to elevated $CO_2$ and temperature. Stomatal conductance of Q. glauca was reduced by 21.7%, but that of Q. gilva was not significantly affected, by long-term exposure to $CO_2$ and temperature. However, the transpiration rate of the two oak species decreased. Water use efficiency of Q. gilva was not significantly affected by elevated $CO_2$ and temperature, while that of Q. glauca was increased by 56.6%. The leaves of Q. gilva grown under treatment conditions had an increased C:N ratio due to their reduced nitrogen content, while those of Q. glauca were not significantly affected by long-term exposure to elevated $CO_2$ and temperature. These results suggest that the long-term responses to elevated $CO_2$ and temperature between Q. gilva and Q. glauca are different, and that Q. gilva, the endangered species, is more sensitive to elevated $CO_2$ and temperature than Q. glauca.

Evaluation of Renal Toxicity by Combination Exposure to Melamine and Cyanuric Acid in Male Sprague-Dawley Rats

  • Son, Ji Yeon;Kang, Yoon Jong;Kim, Kyeong Seok;Kim, Tae Hyung;Lim, Sung Kwang;Lim, Hyun Jung;Jeong, Tae Cheon;Choi, Dal Woong;Chung, Kyu Hyuck;Lee, Byung Mu;Kim, Hyung Sik
    • Toxicological Research
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    • 제30권2호
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    • pp.99-107
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    • 2014
  • Melamine-induced nephrotoxicity is closely associated with crystal formation in the kidney caused by combined exposure to melamine (Mel) and cyanuric acid (CA). However, there are few dosage-finding studies for toxicological evaluation of chronic co-exposure to Mel and CA. The objective of this study was to investigate the possible mechanism by which a Mel and CA mixture lead to renal toxicity in rats. Mel and CA were co-administered to rats via oral gavage for 50 days. Nephrotoxicity was determined by measuring blood urea nitrogen (BUN) and serum creatinine (sCr) levels. Relative kidney weights were significantly increased in rats after co-exposure to Mel+CA (63/6.3 or 630/6.3 mg/kg) mixtures. BUN and sCr levels were significantly increased after Mel and CA co-exposure. Taken together, significant increase in KIM-1, NGAL, and calbindin levels were observed in the urine of rats exposed to Mel+CA (63/6.3 or 630/6.3 mg/kg) compared with the corresponding control group. Histological analysis revealed epithelial degeneration and necrotic cell death in the proximal tubules of the kidney after co-exposure to Mel+CA (63/6.3 or 630/6.3 mg/kg). Our data suggest that Mel-mediated renal toxicity may be influenced by CA concentrations in Mel-contaminated milk or foods.

반도체 FAB근무에 대한 정량적 노출지표 개발 (Development of Quantitative Exposure Index in Semiconductor Fabrication Work)

  • 신규식;김태훈;정현희;조수헌;이경호
    • 한국산업보건학회지
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    • 제27권3호
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    • pp.187-192
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    • 2017
  • Objectives: It is difficult to identify exposure factors in the semiconductor industry due to low exposure levels to hazardous substances and because various processes take place in fabrication (FAB). Furthermore, a single worker often experiences a variety of job histories, so it is difficult to classify similar exposure groups (SEG) in the semiconductor industry. Therefore, we intend to develop a new exposure index, the period of working in FAB, that is applicable to the semiconductor industry. Methods: First, in specifying the classification of jobs, we clearly distinguished whether they were FAB workers or non-FAB workers. We checked FAB working hours per week through questionnaires administered to FAB workers. We derived an exposure index called FAB-Year that can represent the period of working in FAB. FAB-Year is an index that can quantitatively indicate the period of working in FAB, and one FAB-Year is defined as working in FAB for 40 hours per week for one year. Results: A total of 8,453 persons were surveyed, and male engineers and female operators occupied 90% of the total. The average total years of service of the subjects was 9.7 years, and the average FAB-Year value was 6.8. This means that the FAB-working ratio occupies 70% of total years of service. The average FAB-Year value for female operators was 8.4, for male facility engineers it was 7.7, and for male process engineers it was 3.5. A FAB-Year standardization value according to personal information (gender, job group, entry year, retirement year) for the survey subjects can be calculated, and standardized estimation values can be applied to workers who are not participating in the survey, such as retirees and workers on a leave of absence (LOA). Conclusions: This study suggests an alternative method for overcoming the limitations on epidemiological study of the semiconductor industry where it is difficult to classify exposure groups by developing a new exposure index called FAB-Year. Since FAB-Year is a quantitative index, we expect that various approaches will be possible in future epidemiological studies.

수산생물 중 유해물질의 인체 노출 및 위해평가 시스템 개발 (Development of Human Exposure and Risk Assessment System for Chemicals in Fish and Fishery Products)

  • 이재원;이승우;최민규;이헌주
    • 한국환경보건학회지
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    • 제47권5호
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    • pp.454-461
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    • 2021
  • Background: Fish and fishery products (FFPs) unintentionally contaminated with various environmental pollutants are major exposure pathways for humans. To protect human health from the consumption of contaminated FFPs, it is essential to develop a systematic tool for evaluating exposure and risks. Objectives: To regularly, accurately, and quickly evaluate adverse health outcomes due to FFPs contamination, we developed an automated dietary exposure and risk assessment system called HERA (the Human Exposure and Risk Assessment system for chemicals in FFPs). The aim of this study was to develop an overall architecture design and demonstrate the major features of the HERA system. Methods: For the HERA system, the architecture framework consisted of multi-layer stacks from infrastructure to fish exposure and risk assessment layers. To compile different contamination levels and types of seafood consumption datasets, the data models were designed for the classification codes of FFP items, contaminants, and health-based guidance values (HBGVs). A systematic data pipeline for summarizing exposure factors was constructed through down-scaling and preprocessing the 24-hour dietary recalls raw dataset from the Korea National Health and Nutrition Examination Survey (KNAHES). Results: According to the designed data models for the classification codes, we standardized 167 seafood items and 2,741 contaminants. Subsequently, we implemented two major functional workflows: 1) preparation and 2) main process. The HERA system was developed to enable risk assessors to accumulate the concentration databases sustainably and estimate exposure levels for several populations linked to seafood consumption data in KNAHES in a user-friendly manner and in a local PC environment. Conclusions: The HERA system will support policy-makers in making risk management decisions based on a nation-wide risk assessment for FFPs.

생활화학제품의 알레르기반응가능 향료성분 함유 현황 및 동시 출현 패턴 조사 (Characteristics and Co-Occurrence Patterns of Fragrance Allergens in Consumer Chemical Products)

  • 김수민;이기영;임미영
    • 한국환경보건학회지
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    • 제48권4호
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    • pp.206-215
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    • 2022
  • Background: Fragrance substances in consumer products can cause adverse health effects such as contact allergy. In South Korea, consumer chemical products must list 26 known fragrance allergens on product labels when they contain more than 0.01%. Fragrance substances are mostly used in combination, so co-exposure can occur via use of a consumer chemical product. Co-exposure to fragrance allergens may show a synergistic effect on the human body. Objectives: The aims of the study were to analyze the characteristics of fragrance allergens in consumer chemical products available on public websites and to identify the co-occurrence patterns of fragrance allergens. Methods: The chemicals in 1,443 ingredient disclosures for consumer chemical products were collected through the Ecolife database. The 26 labelled fragrance allergens were identified by category of consumer chemical product. The co-occurrence patterns of the 26 labelled fragrance allergens were analyzed by frequent pattern mining. The unlabelled fragrance allergens presented by European Union Scientific Committee on Consumer Safety were also identified. Results: Consumer chemical products contained an average of 5.3±4.2 substances among the 26 labelled fragrance allergens. More than 85% of air fresheners, deodorizing agents, and fabric softeners contained at least one of the 26 labelled fragrance allergens. The most frequently contained fragrance allergens were limonene (50.5%), linalool (49.9%), hexyl cinnamal (34.0%), and citronellol (28.3%). 16.7% of consumer chemical products showed a co-occurrence of limonene, linalool, hexyl cinnamal, and citronellol. Thirty-eight unlabelled fragrance allergens were found in the consumer chemical products, with hexamethylindanopyran (25.2%) being the most frequently contained substance. Conclusions: The characteristics and co-occurrence patterns of 26 labelled fragrance allergens would be useful information for the management of co-exposure to fragrance allergens in consumer chemical products. It is necessary for attention to be paid to unlabelled fragrance allergens.

탄산 시비 농도와 시비 시간이 착색단고추 생육에 미치는 영향 (Effects of $CO_2$ Enrichment Concentration and Duration on Growth of Bell Pepper (Capsicum annuum L.))

  • 강윤임;이시영;김학주;전희;정병룡
    • 생물환경조절학회지
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    • 제16권4호
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    • pp.352-357
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    • 2007
  • 본 연구는 착색단고추의 겨울철 시설재배시 탄산가스 시비의 이용효율을 높이기 위한 시비 농도 및 시간을 구명하기 위해 수행하였다. 탄산가스의 공급 설정농도 수준은 400ppm과 700ppm이였으며, 시비 시간은 09:00-12:00(3h)과 09:00-15:00(6h)로 농도와 시간을 조합한 4 수준과 무처리구를 합하여 5 처리를 하였고, 정식 후 55일간 처리하였다. 그 결과 전반적으로 탄산가스 농도가 높고, 시비시간이 길어질수록 전반적인 생육이 증가하였다. 그러나 겨울철에는 광도가 제한 요소로 작용하기 때문에 탄산가스의 높은 농도보다는 시비 시간이 길어질수록 생육이 더 증가하였다. 그러므로 광이 적은 겨울철에는 높은 농도의 이산화탄소를 짧은 시간 시비하는 것보다 낮은 농도로 긴 시간 시비하는 것이 효율적인 것으로 판단된다.

Comparative Study on Convective and Microwave-Assisted Heating of Zeolite-Monoethanolamine Adsorbent Impregnation Process for CO2 Adsorption

  • Oktavian, Rama;Poerwadi, Bambang;Pardede, Kristian;Aulia, Zuh Rotul
    • Korean Chemical Engineering Research
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    • 제59권2호
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    • pp.260-268
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    • 2021
  • Adsorption is the most promising technology used to adsorb CO2 to reduce its concentration in the atmosphere due to its functional effectiveness. Various porous materials have been extensively synthesized to boost CO2 adsorption efficiency, for example, zeolite. Here, we report the synthesis process of zeolite adsorbent impregnated with amine, combining the benefit of these two substances. We compared conventional heating with microwave-assisted heating by varying concentrations of monoethanolamine in methanol (10% v/v and 40% v/v) as a liquid solution. The results showed that monoethanolamine impregnation helps significantly increase adsorption capacity, where adsorption occurs as a physisorption and not as chemisorption due to the adsorbent's steric hindrance effect. The highest adsorption capacity of 0.3649 mmol CO2 / gram adsorbent was reached by microwave exposure for 10 minutes. This work also reveals that a decrease in CO2 adsorption capacity was observed at a longer exposure period, and it reached a constant 40-minute adsorption rate. Impregnating activated zeolite with 40% monoethanolamine for 10 minutes in addition to microwave exposure (0.8973 mmol CO2 / gram adsorbent) is the maximum adsorption ability achieved.

Improved dynamic range of the camera image by using double-exposure image processing method for mobile phone cameras

  • Jang, Won-Woo;Kwak, Boo-Dong;Ha, Joo-Young;Kang, Bong-Soon;Lee, Gi-Dong
    • Journal of information and communication convergence engineering
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    • 제7권3호
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    • pp.323-329
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    • 2009
  • In this paper, we propose the improvement method of the camera images regardless of exposure environments. By using a double-exposure method, we could improve camera images with clear recognition. We applied the improvement method on the mobile phone. For the feasibility of the proposed algorithm, we compared simulated camera images with the proposed method to conventional images by using auto-exposure image. Experimental results are also shown in this paper.

Possible Biomarker Gene for Radiation Workers in Hospital

  • Jin, Young-Woo;Jeong, Mee-Seon;Moon, Kien;Lee, Chee-Young;Bae, Sang-Woo;Choi, Soo-Yong;Lee, Yun-Sil
    • Molecular & Cellular Toxicology
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    • 제5권2호
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    • pp.165-171
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    • 2009
  • Biomarkers indicating past exposure to radiation have not yet been entirely satisfactory. In this study, we validated several genes reported as radiation response genes, as biomarkers to detect past exposure to radiation in occupationally exposed workers, especially workers in the medical field. A total of 54 radiation workers in hospital were investigated for radiation exposure dose. Their average radiation dose of recent one year was 1.09 mSv ($\pm$1.63) with a 10.63 mSv ($\pm$12.91) cumulative dose. The results of the multiple regression analysis for the various variables indicate that the Hsc70 (P=0.0292) and ORAL (P=0.0045) may be candidate biomarkers for the recent 1 year radiation exposure in radiation workers, whereas AEN (P=0.0334) and PGAMI (P=0.0003) might be for cumulative exposure.

금속 패터닝과 Blank노광을 이용한 감광성 유리의 미세가공 (Microfabrication of Photosensitive Glass Using Metal Patterning and Blank Exposure)

  • 조재승;강형범;윤혜진;김효진;임현우;조시형;임실묵
    • 한국표면공학회지
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    • 제46권3호
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    • pp.99-104
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    • 2013
  • The simple and cost-effective microfabrication method of photosensitive glass (PSG) using metal patterning and blank exposure was proposed. Conventional photolithography for micromachining of PSG needs a costly quartz mask which has high transmittance as an optical property. However, in this study the process was improved through the combination of micro-patterned Ti thin film and blank UV exposure without quartz mask. The effect of UV exposure time as well as the DHF etching condition was investigated. UV exposure test was performed within the range from 3 min to 9 min. The color and etch result of PSG exposed for 5 min were the most clear and effective to etch more precisely, respectively. The etching results of PSG in diluted hydrofluoric acid (DHF) with a concentration of 5, 10, 15 vol% were compared. The effect on the side etch was insignificant while the etch rate was proportional as the concentration increased. 10 vol% DHF results not only high etch rate of 75 ${\mu}m/min$ also lower side etch value after PSG etching. This method facilitates the microfabrication of PSG with various patterns and high aspect ratio for applying to advanced applications.