• 천문학회보
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• 제38권1호
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• pp.70.1-70.1
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• 2013

New space program for "Next-Generation Small Satellite (NEXTSat)" launched last year after the success of the series of Science & Technology Satellite (STSAT). KASI proposed the near-infrared imaging spectrometer as a scientific payload onboard NEXTSat-1. It was selected as one of two scientific payloads. The approved scientific payload is the near-infrared imaging spectrometer for the study of star formation history (NISS). The efficient near-infrared observation can be performed in space by evading the atmospheric emission as well as other thermal noise. The observation of cosmic near-infrared background enables us to reveal the early Universe in an indirect way through the measurement of absolute brightness and spatial fluctuation. The detection of near-infrared spectral lines in nearby galaxies, cluster of galaxies and star forming regions give us less biased information on the star formation. In addition, the NISS will be expected to demonstrate our technologies related to the development of the Korea's leading near-infrared instrument for the future large infrared telescope, SPICA.

• Nutrition Research and Practice
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• 제13권1호
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• pp.64-69
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• 2019

BACKGROUND/OBJECTIVES: Alzheimer's disease is a neurodegenerative disease that induces symptoms such as a decrease in motor function and cognitive impairment. Increases in the aggregation and deposition of amyloid beta protein ($A{\beta}$) in the brain may be closely correlated with the development of Alzheimer's disease. In this study, the effects of an adzuki bean extract on the aggregation of $A{\beta}$ were examined; moreover, the anti-Alzheimer's activity of the adzuki extract was examined. MATERIALS/METHODS: First, we undertook thioflavin T (ThT) fluorescence analysis and transmission electron microscopy (TEM) to evaluate the effect of an adzuki bean extract on $A{\beta}_{42}$ aggregation. To evaluate the effects of the adzuki extract on the symptoms of Alzheimer's disease in vivo, $A{\beta}_{42}$-overexpressing Drosophila were used. In these flies, overexpression of $A{\beta}_{42}$ induced the formation of $A{\beta}_{42}$ aggregates in the brain, decreased motor function, and resulted in cognitive impairment. RESULTS: Based on the results obtained by ThT fluorescence assays and TEM, the adzuki bean extract inhibited the formation of $A{\beta}_{42}$ aggregates in a concentration-dependent manner. When $A{\beta}_{42}$-overexpressing flies were fed regular medium containing adzuki extract, the $A{\beta}_{42}$ level in the brain was significantly lower than that in the group fed regular medium only. Furthermore, suppression of the decrease in motor function, suppression of cognitive impairment, and improvement in lifespan were observed in $A{\beta}_{42}$-overexpressing flies fed regular medium with adzuki extract. CONCLUSIONS: The results reveal the delaying effects of an adzuki bean extract on the progression of Alzheimer's disease and provide useful information for identifying novel prevention treatments for Alzheimer's disease.

• 한국경제지리학회지
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• 제27권1호
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• pp.38-52
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• 2024

산업생산 전반의 생산성 향상에 기여하는 디지털전환 산업과 함께 탄소중립 및 지속가능 성장을 위한 스마트그린 산업이 미래산업으로 성장하고 있다. 이 논문은 스마트그린 산업의 성장 동인과 입지패턴 변화 분석을 통해 미래산업 혁신생태계에서의 동 산업의 위상 및 역할 모색을 연구목적으로 한다. 동 산업은 수도권과 비수도권 모든 지역에서 증가세를 보이며, 비수도권 비도시 지역에서도 뚜렷한 산업 성장세를 확인할 수 있다. 특히, 스마트 그린 산단 시범사업, 광주전남 혁신도시 조성, 신재생에너지 정책 추진 등으로 호남권 및 충남 해안지역의 핵심 집적지(HH형) 부상, 경상권 지역에 고립 중심지(HL형) 형성 등 비수도권 지역에서 신재생에너지 생산기업의 집적이 이루어지고 있다. 따라서 스마트그린 산업은 정책적 요인이 성장 촉발 요인이며, 다극형 허브(Hub)-스포크(Spoke) 네트워크 구조를 형성하는 미래산업 혁신생태계에서 비도시지역의 다양한 특성화 소거점(Spoke) 형성을 촉진할 것으로 기대된다.

• 한국전산유체공학회지
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• 제15권2호
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• pp.7-13
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• 2010

Flight vehicles such as wheel wells and bomb bays have many cavities. The flow around a cavity is characterized as an unsteady flow because of the formation and dissipation of vortices brought by the interaction between the free stream shear layer and the internal flow of the cavity. The resonance phenomena can damage the structures around the cavity and negatively affect the aerodynamic performance and stability of the vehicle. In this study, a numerical analysis was performed for the cavity flows using the unsteady compressible three-dimensional Reynolds-Averaged Navier-Stokes (RANS) equation with Wilcox's turbulence model. The Message Passing Interface (MPI) parallelized code was used for the calculations by PC-cluster. The cavity has aspect ratios (L/D) of 5.5 ~ 7.5 with width ratios (W/D) of 2 ~ 4. The Mach and Reynolds numbers are 0.4 ~ 0.6 and $1.6{\times}10^6$, respectively. The occurrence of oscillation is observed in the "shear layer and transient mode" with a feedback mechanism. Based on the Sound Pressure Level (SPL) analysis of the pressure variation at the cavity trailing edge, the dominant frequencies are analyzed and compared with the results of Rossiter's formula. The dominant frequencies are very similar to the result of Rossiter's formula and other experimental datum in the low aspect ratio cavity (L/D = ~4.5). In the high aspect ratio cavity, however, there are other low dominant frequencies of the leading edge shear layer with the dominant frequencies of the feedback mechanism.

• 천문학회보
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• 제40권1호
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• pp.67.4-68
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• 2015

We present a multi-wavelength observational study of a low-mass star-forming region, L1251-C, with observational results at wavelengths from the near-infrared to the millimeter. Spitzer Space Telescope observations confirmed that IRAS 22343+7501 is a small group of protostellar objects. The extended emission to east-west direction with its intensity peak at the center of L1251A has been detected at 350 and 850 mm with the CSO and JCMT telescopes, tracing dense envelope materials around L1251A. The single-dish data from the KVN and TRAO telescopes show inconsistencies between the intensity peaks of several molecular line emission and that of the continuum emission, suggesting complex distributions of molecular abundances around L1251A. The SMA interferometer data, however, show intensity peaks of CO 2-1 and $^{13}CO$ 2-1 located at the position of IRS 1, which is both the brightest source in IRAC image and the weakest source in the 1.3 mm dust continuum map. IRS 1 is the strongest candidate for being the driving source of a newly detected the compact CO 2-1 outflow. Over the whole region ($14^{\prime}{\times}14^{\prime}$) of L125l-C, 3 Class I and 16 Class II sources have been detected, including three YSOs in L1251A. A comparison with the average projected distance among 19 YSOs in L1251-C and that among 3 YSOs in L1251A suggests L1251-C is an example of low-mass cluster formation, where protostellar objects are forming in a small group.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2009년 추계학술대회논문집
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• pp.13-18
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• 2009

Flight vehicles such as wheel wells and bomb bays have many cavities. The flow around a cavity is characterized as an unsteady flow because of the formation and dissipation of vortices brought about by the interaction between the free stream shear layer and the internal flow of the cavity. The resonance phenomena can damage the structures around the cavity and negatively affect the aerodynamic performance and stability of the vehicle. In this study, a numerical analysis was performed for the cavity flows using the unsteady compressible three-dimensional Reynolds-Averaged Navier-Stokes (RANS) equation with Wilcox's turbulence model. The Message Passing Interface (MPI) parallelized code was used for the calculations by PC-cluster. The cavity has aspect ratios (L/D) of 2.5 ~ 7.5 with width ratios (W/D) of 2 ~ 4. The Mach and Reynolds numbers are 0.4 ~ 0.6 and $1.6{\times}106$, respectively. The occurrence of oscillation is observed in the "shear layer and transient mode" with a feedback mechanism. Based on the Sound Pressure Level (SPL) analysis of the pressure variation at the cavity trailing edge, the dominant frequencies are analyzed and compared with the results of Rossiter's formula. The dominant frequencies are very similar to the result of Rossiter's formula and other experimental data in the low aspect ratio cavity (L/D = ~ 4.5). In the large aspect ratio cavity, however, there are other low dominant frequencies due to the leading edge shear layer with the dominant frequencies of the feedback mechanism. The characteristics of the acoustic wave propagation are analyzed using the Correlation of Pressure Distribution (CPD).

• Journal of Welding and Joining
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• 제15권4호
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• pp.126-135
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• 1997

$H_2/O_2$ 비에 따른 Hybrid HVOF 용사된 $Cr_3C_2$-7wt%(NiCr) 용사층의 특성 및 산화거동 This study was performed to investigate the influence of fuel/oxygen ratio (F/O=3.2, 3.0, 2.8) on the characteristics and the oxidation behavior of the hybrid-HVOF sprayed $Cr_3C_2$-7wt%NiCr coatings. Decomposition and the oxidation of the $Cr_3C_2$was occured during spraying. The degree of transformation from $Cr_3C_2$to $Cr_7C_3$ was increased with decreasing the F/O ratio. The microstructural differences of the as sprayed coating with F/O ratio can not be distinguished, However, large pores were diminished and then the coatings became dense by heat treatment. Microhardness of the as-sprayed specimen which sprayed with F/O=3.0 condition was hightest ($Hv_{300}$=1140) and the hardness was increased to 1500 after heat treatment at $600^{\circ}C$ for 50hrs in air. It was supposed that hardness was increased due to the formation of $Cr_2O_3$ within $Cr_3C_2$/$Cr_7C_3$matrix and the densification of coating layer during heat treatment. Apparent activation energy for oxidation was varied from 21.2 kcal$mol^{-1}K^{-1}$ to 23.8 kcal$mol^{-1}K^{-1}$ with respect to the F/O ratio. The surface morphology was changed to porous and oxide chusters were grown after oxidation $1000^{\circ}C$ for 50 hours by the aggressive evolution of gas phase ($CrO_3$ and$CO_2$). The oxide cluster was composed of Ni and Cr.

• 한국재료학회지
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• 제17권1호
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• pp.11-17
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• 2007

Turbulent in-situ mixing process is a new material process technology to get dispersed phase in nanometer size by controlling reaction of liquid/solid, liquid/gas, flow ana solidification speed simultaneously. In this study, mixing which is the key technology to this synthesis method was studied by computational fluid dynamics. For the simulation of mixing of liquid metal, static mixers investigated. Two inlets for different liquid metal meet ana merge like 'Y' shape tube having various shapes and radios of curve. The performance of mixer was evaluated with quantitative analysis with coefficient of variance of mass fraction. Also, detailed plots of intersection were presented to understand effect of mixer shape on mixing. The simulations show that the Reynolds number (Re) is the important factor to mixing and dispersion of $TiB_2$ particles. Mixer was designed according to the simulation, and $Cu-TiB_2$ nano composites were evaluated. $TiB_2$ nano particles were uniformly dispersed when Re was 1000, and cluster formation and reduction in volume fraction of $TiB_2$ were found at higher Re.

• Journal of Microbiology and Biotechnology
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• 제19권10호
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• pp.1092-1097
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• 2009

A novel exopolysaccharide named Ebosin was produced by Streptomyces sp. 139, with medicinal activity. Its biosynthesis gene cluster (ste) has been previously identified. For the functional study of the ste7 gene in Ebosin biosynthesis, it was disrupted with a double crossover via homologous recombination. The monosaccharide composition of EPS-7m produced by the mutant strain Streptomyces sp. 139 ($ste7^-$) was found altered from that of Ebosin, with fucose decreasing remarkably. For biochemical characterization of Ste7, the ste7 gene was cloned and expressed in Escherichia coli BL21. With a continuous coupled spectrophotometric assay, Ste7 was demonstrated to have the ability of catalyzing the transfer of fucose specifically from GDP-$\beta$-L-fucose to a fucose acceptor, the lipid carrier located in the cytoplasmic membrane of Streptomyces sp. 139 ($ste7^-$). Therefore, the ste7 gene has been identified to code for a fucosyltransferase, which plays an essential role in the formation of repeating sugars units during Ebosin biosynthesis.

• 한국지역지리학회지
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• 제18권4호
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• pp.400-413
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• 2012

본 연구는 지방첨단산업단지의 형성과정과 특성을 살펴보기 위해 오창과학단지를 사례로 입주한 기업체의 업종별, 종사자 수규모별 특성과 기업의 이전과정을 분석하였다. 분석 자료는 기업통계 자료와 기업체들을 대상으로 설문조사 내용이었으며 분석 결과는 다음과 같다. 첫째, 오창과학단지에 입지한 기업체들은 IT산업과 BT산업이 혼재되어 나타났다. 둘째, 오창과학단지 내에 입주한 기업들의 규모별 특성은 대기업보다는 중소규모의 기업체가 많았다. 그리고 입주한 기업들은 새로운 상품을 개발하고 마케팅을 하는 단계에 있으며, 핵심적인 기술이나 벤처 인증을 받은 혁신성이 높은 부품 소재 업체들이 많았다. 셋째 오창과학단지에 입주한 기업들은 수도권과 충청권에서 이주한 기업의 비율이 높았고 본사와 함께 입주한 비율이 70% 이상을 차지했다. 넷째 기업들은 생산품 유형과 기술의 보유 정도에 따라 크게 4가지 유형으로 분류되었다.