• Title/Summary/Keyword: Clonal selection

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The Role of Dendritic Cells in Central Tolerance

  • Oh, Jaehak;Shin, Jeoung-Sook
    • IMMUNE NETWORK
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    • v.15 no.3
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    • pp.111-120
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    • 2015
  • Dendritic cells (DCs) play a significant role in establishing self-tolerance through their ability to present self-antigens to developing T cells in the thymus. DCs are predominantly localized in the medullary region of thymus and present a broad range of self-antigens, which include tissue-restricted antigens expressed and transferred from medullary thymic epithelial cells, circulating antigens directly captured by thymic DCs through coticomedullary junction blood vessels, and peripheral tissue antigens captured and transported by peripheral tissue DCs homing to the thymus. When antigen-presenting DCs make a high affinity interaction with antigen-specific thymocytes, this interaction drives the interacting thymocytes to death, a process often referred to as negative selection, which fundamentally blocks the self-reactive thymocytes from differentiating into mature T cells. Alternatively, the interacting thymocytes differentiate into the regulatory T (Treg) cells, a distinct T cell subset with potent immune suppressive activities. The specific mechanisms by which thymic DCs differentiate Treg cells have been proposed by several laboratories. Here, we review the literatures that elucidate the contribution of thymic DCs to negative selection and Treg cell differentiation, and discusses its potential mechanisms and future directions.

Clonal Selection in Early Potato Breeding Program and Determination of Plant Maturity by Using a Plug Culture System (감자(Solanum tuberosum L.)의 육종 초기세대에서 플러그 육묘법을 이용한 계통선발 및 숙기 구분)

  • Kim, Kwan-Soo;Cho, Hyun-Mook;Park, Young-Eun;Lim, Hak-Tae;Song, Yoong-Narm
    • Horticultural Science & Technology
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    • v.19 no.3
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    • pp.329-333
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    • 2001
  • The study was performed to investigate the effect of a plug culture method in the early stage of a potato breeding program. The 105, 200 and 288-cell plug trays were used for raising potato seedlings. The % germination in plug trays ranged between 94 and 96%. Percent tuberization measured at 50 and 60, and 70 days after sowing was the greatest in 105-cell and 200-cell trays, respectively. However, tuberization was most delayed in 288-cell trays. Thus, it is considered that 105-cell tray is the most effective for the selection of early maturing plants. Plant maturity was determined by the morphological characteristics at the seedling stage of stolons cultured in plug trays. Most of seedlings with shorter stolons at seedling stage (1st generation) were the early-maturing, while most of seedlings with longer stolons were the late-maturing at the clonal stage (2nd generation). These results mean that the plant maturity in the early potato breeding program can be effectively grouped by observing the morphological characteristics of stolons after plug culture.

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Cooperative Strategies and Swarm Behavior in Distributed Autonomous Robotic Systems based on Artificial Immune System

  • Sim, Kwee-bo;Lee, Dong-wook
    • Journal of the Korean Institute of Intelligent Systems
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    • v.11 no.7
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    • pp.591-597
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    • 2001
  • In this paper, we propose a method of cooperative control (T-cell modeling) and selection of group behavior strategy (B-cell modeling) based on immune system in distributed autonomous robotic system (DARS). Immune system is living body's self-protection and self-maintenance system. These features can be applied to decision making of optimal swarm behavior in dynamically changing environment. For applying immune system to DARS, a robot is regarded as a B-cell, each environmental condition as an antigen, a behavior strategy as an antibody and control parameter as a T-cell respectively. The executing process of proposed method is as follows. When the environmental condition changes, a robot selects an appropriate behavior strategy. And its behavior strategy is stimulated and suppressed by other robot using communication. Finally much stimulated strategy is adopted as a swarm behavior strategy. This control school is based on clonal selection and idiotopic network hypothesis. And it is used for decision making of optimal swarm strategy. By T-cell modeling, adaptation ability of robot is enhanced in dynamic environments.

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Teak (Tectona grandis Linn. f.): A Renowned Commercial Timber Species

  • Palanisamy, K.;Hegde, Maheshwar;Yi, Jae-Seon
    • Journal of Forest and Environmental Science
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    • v.25 no.1
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    • pp.1-24
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    • 2009
  • Teak (Tectona grandis) is one of the most valuable timber yielding species in the world, with predominant distribution in tropical or sub-tropical countries. However, natural teak available only in few countries like India, Myanmar, Laos People's Democratic Republic and Thailand. Teak grows well in deep, well-drained alluvial soils, fairly moist, warm, tropical climate with pH ranges from 6.5-7.5. Teak is cultivated in many Asian, African and South American countries for timber production. The global teak plantations are estimated to be three million hectare with major share in India (44%) followed by Indonesia (33%). India is considered as richest genetic resources of teak with large areas of natural teak bearing forests (8.9 million ha), plantations (1.5 million ha), clonal seed orchards (1000 ha) and seed production areas (5000 ha). The studies on diversity of teak populations showed that teak is an out crossing species with major portion of diversity present within the populations. The productivity and quality of teak timber varies depending upon the site and environmental conditions. Teak wood is moderately heavy, strong and tough,straight grained, coarse textured and ring porous with specific gravity varies from 0.55 to 0.70. The sapwood is white to pale yellow in colour and clearly demarcated while heartwood is dark brown or dark golden yellow in colour. Teak is one of the most durable timbers in the world, practically, impervious to fungus and white ant attack and resistant to decay. Teak wood is used in ship and boat constructions, furnitures and aesthetic needs. Genetic improvement programmes have been undertaken in countries like Thailand, India, Malaysia and Indonesia. The programme includes provenance identification and testing, plus tree selection and clonal multiplication, establishment of seed orchards and controlled hybridization. Several aspects like phenology, reproductive biology, fruit characteristics, silvicultural practices for cultivation, pest and diseases problems, production of improved planting stock, harvesting and marketing, wood properties and future tree improvement strategy to enhance productivity have been discussed in this paper.

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Dynamic behavior control of a collective autonomous mobile robots using artificial immune networks (인공면역네트워크에 의한 자율이동로봇군의 동적 행동 제어)

  • 이동욱;심귀보
    • 제어로봇시스템학회:학술대회논문집
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    • 1997.10a
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    • pp.124-127
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    • 1997
  • In this paper, we propose a method of cooperative control based on immune system in distributed autonomous robotic system(DARS). Immune system is living body's self-protection and self-maintenance system. Thus these features can be applied to decision making of optimal swarm behavior in dynamically changing environment. For the purpose of applying immune system to DARS, a robot is regarded as a B lymphocyte(B cell), each environmental condition as an antigen, and a behavior strategy as an antibody respectively. The executing process of proposed method is as follows. When the environmental condition changes, a robot selects an appropriate behavior strategy. And its behavior strategy is simulated and suppressed by other robot using communication. Finally much simulated strategy is adopted as a swarm behavior strategy. This control scheme is based on clonal selection and idiotopic network hypothesis. And it is used for decision making of optimal swarm strategy.

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Optimal nonlinear Parameter Estimation of Steady-State Induction Motor using Immune Algorithm

  • Kim, Dong-Hwa;Cho, Jae-Hoon;Hong, Won-Pyo;Lee, Seung-Hack;Lee, Hwan
    • 제어로봇시스템학회:학술대회논문집
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    • 2004.08a
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    • pp.891-895
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    • 2004
  • This paper suggests the techniques in determining the values of the steady-state equivalent circuit parameters of a three-phase squirrel-cage induction machine using immune algorithm. The parameter estimation procedure is based on the steady state phase current versus slip and input power versus slip characteristics. The proposed estimation algorithm is of a nonlinear kind based on clonal selection in immune algorithm. The machine parameters are obtained as the solution of a minimization of least-squares cost function by immune algorithm. Simulation shows better results than the conventional approaches.

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Intelligent Parameter Estimation of a Induction Motor Using Immune Algorithm

  • Kim, Dong-Hwa;Cho, Jae-Hoon
    • Proceedings of the Korean Institute of Intelligent Systems Conference
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    • 2004.10a
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    • pp.21-25
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    • 2004
  • This paper suggests the techniques in determining the values of the steady-state equivalent circuit parameters of a three-phase squirrel-cage induction machine using immune algorithm. The parameter estimation procedure is based on the steady state phase current versus slip and input power versus slip characteristics. The proposed estimation algorithm is of a nonlinear kind based on clonal selection in immune algorithm. The machine parameters are obtained as the solution of a minimization of least-squares cost function by immune algorithm. Simulation shows better results than the conventional approaches.

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Artificial immune network-based cooperative beharior strategies in collective autonomous mobile rotos (인공면역계 기반의 자율이동로봇군의 협조행동전략 결정)

  • 이동욱;심귀보
    • Journal of the Korean Institute of Telematics and Electronics S
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    • v.35S no.3
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    • pp.102-109
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    • 1998
  • In this paper, we propose a method of cooperative control based on immune system in distributed autonomous robotic system(DARS). Immune system is living body's self-protection and self-maintenance system. Thus these features can be applied to decision making of optimal swarm behavior in dynamically changing environment.For the purpose of applying immune system to DARS, a robot is regarded as a B lymphocyte(B cell), each environmental condition as an antigen, and a behavior strategy as an antibody respectively. The executing process of proposed method is as follows. When the environmental codintion changes, a robot select an appropriate beharior stategy. And its behavior stategy is stimulated and suppressed by other robot using communiation. Finally much stimulated strategy is adopted as a swarm behavior strategy. This control scheme is based on clonal selection and idotopic network hypothesis. And it is used for decision making of optimal swarm stragegy.

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Freezing Resistance of Cryptomeria japonica - Its clonal and Seasonal Differences - (삼나무의 내한성(耐寒性) - 품종별(品種別) 채취시기별(採取時期別) 차이(差異) -)

  • Hwang, Jeung;Hong, Sung Gak
    • Journal of Korean Society of Forest Science
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    • v.39 no.1
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    • pp.47-56
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    • 1978
  • This study aimed to know difference in freezing resistance among different clonal seedlings or different seed source seedlings of Cryptomeria japonica which has been selected where extreme cold prevails in Korea and Japan. The freezing resistance of three 12-50 year old trees was also measured in the experiment. The freezing resistance was measured in different tissue parts: mainly leaf, cambiam and xylem, at three different collection dates in two different collection places during the winter of 1977-1978. The following results and discussions were made: 1. The clonal difference in freezing resistance of Cryptomeria japonica was $9^{\circ}$ to $15^{\circ}C$ in maximum according to the collection place. However, the clonal difference in freezing resistance was not related to the difference in climatic conditions where the parent tree have been growing. This impiled that the natural selection of cold resistant genes in Cryptomeria japonica has not reached its evolutional equilibrium yet since most of the Cryptomeria forest has been established by artificial regeneration. 2. The difference in freezing resistance among leaf, cambium and xylem was not apparent except that leaf of several clones showed higher freezing resistance than cambium or xylem when they collected at mid-winter. The least freezing resistant tissue part, thought its freezing resistance was not measure in all clones and all temperatures were appeared in the apical buds. The new shoot growth was observed in the next spring with being replaced by its dormant or adventitious bud growth when the apical bud was injured dy cold during winter. 3. The freezing resistance of leaf, cambium and xylem was shown high enough so that freezing resistance Cryptomeria clones in this experiment were supposed to be able to survive in cold winter conditions at the middle part of Korea. However, it was reported that the most susceptible tissue part to winter injury was the basal stem, but of which freezing resistance was not-measured in this experiment. Several silvicultural methods for prevention of Cryptomeria seedlings from cold damage were discussed in literature.

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Selection of New Cultivars with Red Fall Leaf Color in Zelkova serrata Makino as Street Trees (가로수용 적색 단풍 느티나무(Zelkova serrata Makino) 신품종 선발)

  • 심경구;하유미;박형순;이정호
    • Journal of the Korean Institute of Landscape Architecture
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    • v.27 no.2
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    • pp.1-8
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    • 1999
  • This study was carried out to develop new cultivars of Z. serrata showing red fall leaf as street trees. Z. serrata which had red fall leaves were selected and then examined for contents of leaf anthocyanin and chlorophyll. In addition, for the progeny test, selected trees were grafted. Of 21 trees having red autumn leaves, three individuals, 'S-6', 'S-20', and 'I-24' were finally selected. They contained higher level of anthocyanin in the leaves. Once developed, the red color remained till late autumn. Grafted plants of the selected strains showed high grafting efficiency and red foliage color in autumn. The soil pH of the survey sites ranged from 5.9 to 7.24. However, other soil characteristics did not show much difference among the sites with regard to inorganic nutrients including N(%), $P_2O_5$, CEC(mg/meq), $K^+$, $Ca^{3+}$, and $Mg^{2+}$, 'S-6', 'S-20', and 'I-24', clonal lines with red fall leaf were selected as new cultivars and propagates by grafting.

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