• Parasites, Hosts and Diseases
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• 제33권3호
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• pp.219-224
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• 1995

새인두흡충에 의한 인체감염 제1례를 보고한다. 환자는 56세 된 남자로서 3-4일간의 인후부 이 물감과 염증성 증상으로 이비인후과의원을 방문하여 오른쪽 인두 후벽에 흡착한 충체를 제거하였다. 충체는 Clnostoumum complanatum으로 동정되었다. 환자는 평소 담수어의 생식을 즐겼으며 의원 방문 4일전에도 낚시로 포획한 담수어를 생식한 적이 있었다. 우리 나라에서도 이 흡충에 의한 인두염의 예방을 위해 담수어의 생식에 더 깊은 주의가 요망된다고 생각된다. Clinostomum complanatum의 우리 말 이름을 새인두흡충으로 제안한다.

• 한국어병학회지
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• 제25권2호
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• pp.85-93
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• 2012

노지 양식장에서 비단잉어와 함께 사육중인 참붕어의 미병부, 체측근, 복부 및 아가미 뚜껑 내부에 황백색의 cyst내의 metacercaria를 탈낭시켜 형태학적 및 분자생물학적으로 조사한 결과 Clinostomum complanatum으로 동정되었다. 병리조직학적으로는 상피세포의 박리와 괴사 및 cyst주변의 근섬유의 위축이외에 다른 조직의 변화는 발견되지 않았다.

• 한국임상수의학회지
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• 제25권4호
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• pp.307-309
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• 2008

The metacercariae species have often been isolated from fresh water fish in Korea. In this study, we reported Clinostomum complanatum, a species of metacercariae isolated from gill and muscle of Korean barbel (Hemibarbus mylodon), a natural monument fresh water fish in Korea, by morphological observation. The excysted metacercariae, tongue-shaped and progenetic, were 3.11-4.62 mm in length and 0.90-1.43 mm in width. Fresh water fishes are known as the second intermediate hosts of C. complanatum. This is the first isolation report from Korean barbel.

• Parasites, Hosts and Diseases
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• 제57권2호
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• pp.175-177
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• 2019

A 46-year old man visited our outpatient clinic with complaint of foreign body sensation in throat after consuming raw freshwater fish 5 days ago. Laryngoscopic examination revealed a motile worm attached on posterior pharyngeal wall. The worm was removed using biopsy forceps under transnasal endoscopy and evidently identified as Clinostomum complanatum after microscopic examination. Patient's subjective foreign body sensation of throat and hyperemia of laryngeal mucosa remained for approximately 2 weeks post-removal, which were eventually resolved after administration of non-steroidal anti-inflammatory drug and anti-refluxant drug for 2 weeks. Treatment was ended at three weeks since the first visit. C. complanatum infections in humans are rare, and only four cases have been reported in Korea. Symptoms resembling pharyngitis or laryngitis occurs by consumption of raw, infected freshwater fish and treatment is done by mechanically removing the parasite.

• 한국임상수의학회지
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• 제31권4호
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• pp.354-356
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• 2014

Clinostomum (C.) complanatum is one of the trematode helminthes in birds and causes incidental infection in human. A black-tailed gull (Larus crassirostris) was referred to the Jeju wildlife rescue center. Because of the death of bird after two weeks treatment, necropsy was performed to the bird. Grossly, many living worms adhered to the oral mucosa including pharynx and esophagus were observed. The worms removed were identified as C. complanatum after morphological observation. The linguiform adult worms were $5.19{\pm}0.48mm$ long and $1.80{\pm}0.18mm$ wide. Histopathologically, severe necrosis and surrounding inflammation were observed at the infection sites of adult worm in pharynx and esophagus. This is the first report for C. complanatum infection in wild black-tailed gull in Korea.

• 한국어병학회지
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• 제24권2호
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• pp.161-166
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• 2011

경상북도 영덕군의 하천에 서식하는 점몰개 spotted barbel gudgeon (Squalidus multimaculatus Hosoya et Jeon)의 근육에서 새인두흡충 Clinostomum complanatum (Rudolphi, 1814)의 피낭유충이 발견되었다. 감염된 점몰개는 "yellow grub"인 기생충의 피낭유충으로 인해 표면이 울퉁불퉁하게 보였으며, 수면위에 힘없이 유영하였고 일부 폐사한 개체도 발견되었다. 분리된 탈낭유충의 형태는 혓바닥모양이었으며, 크기는 2.85~5.89 mm${\times}$0.8~1.99 mm였다. 어체당 1~98개의 피낭유충을 분리하였으며 평균 감염수는 25개로 나타났다. 특히, 성어크기인 평균 7cm 정도의 점몰개는 100% 감염되어 있었다. 본 연구는 한국의 자연수계에 서식하는 어류에서 C. complanatum 의해 질병이 발생하고 폐사가 일어난 첫 보고이다.

• Parasites, Hosts and Diseases
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• 제47권4호
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• pp.401-404
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• 2009

A 33-year-old Korean man visited a medical clinic with complaints of throat discomfort and pain for one week. The symptoms occurred one day after eating raw brackish water fish, perch. Endoscopy revealed a fluke, about 5 mm in length, attaching to and peristaltically moving on the surface of the mucosa at the arytenoid region of the larynx. Microscopically, the testes were triangular, tandem, and separated by the uterus. The ovary and cirrus pouch were placed apart from median line between testes. Numerous blood cells were observed in the ceca. The worm was identified to be Clinostomum complanatum. This is the second human case of clinostomiasis in Korea.

• 한국어병학회지
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• 제9권1호
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• pp.1-9
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• 1996

1995년 8월 전북소재 금붕어 양어지에서 금붕어의 체표 근육에 기생한 흡충, Clinostomum complanatum의 피낭 유충을 다량 검출 하였다. 피낭 유충의 크기는 $700\sim877{\times}700\sim775{\mu}m$었고, 탈낭 유충은 $2.4\sim5.5{\times}0.7\sim1.37mm$로서, 창자 내부의 황색 과립상 물질 때문에 충체는 황색으로 보인다. 충체의 앞쪽에는 $125\sim225{\times}175\sim300{\mu}m$의 구흡반이 있고, 복흡반은 $500\sim750{\times}525\sim750{\mu}m$크기로 충체의 앞쪽 1/4부위에 위치 한다. 어체 1마리당 최고 1,214개, 최저 1개가 기생 되었고, 총 276마리의 조사어에서 84.78%(234마리)의 기생율을 나타냈으며, 기생율이 가장 높은 크기는 체장 2.0~2.5cm로 94.29%, 가장 낮은 크기는 3.1~3.5cm 로 75.27%이었다. 어체 부위중 B(협부)가 가장 많이 기생(43.65%)되었고, C(가슴)부분이 가장 적게 기생(4.4%)되었다. 캬리코와 유금의 양종간에는 기생율에 큰 차이가 없었다. 본 충의 기생부위는 직경 0.4~0.8mm의 황색점으로 보이고, 그 부위는 팽융되어 울퉁불퉁하다. 200개 이상의 피낭유충이 기생된 금붕어는 수면위에 힘없이 유영하거나 쇠약해저서 폐사되었고, 특히 선별후 폐사 개체가 많았다.

• Parasites, Hosts and Diseases
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• 제57권4호
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• pp.389-397
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• 2019

The infection status of Clinostomum complanatum metacercariae (CcMc) was broadly surveyed in fishes from water systems of Nakdong-gang (River) in the Republic of Korea (Korea) for 5 years. All 4,468 fishes collected were individually examined by the artificial digestion methods. No CcMc were detected in fishes from Naeseongcheon in Yecheongun, Gigyecheon in Gyeongju-si, Gyeongsangbuk-do, and Hamancheon in Haman-gun, Gyeongsangnam-do. In fishes from Wicheon in Gunwi-gun, Gyeongsangbuk-do, CcMc were detected in 180 (15.4%) out of 1,168 fishes and their intensity was 5.8 per fish infected. The prevalences with CcMc in positive fish species from 3 other surveyed areas, i.e., Banbyeoncheon in Yeongyang-gun, Nakdong-gang in Sangju-si and Hoecheon in Goryeong-gun, in Gyeongsangbuk-do were 19.3%, 33.3%, and 19.0% and their intensities were 1.5, 17.6, and 2.6 per fish infected respectively. In fishes from Yangcheon in Sancheong-gun, Gyeongsangnam-do, CcMc were detected in 811 (45.6%) out of 1,779 fishes examined and their intensity was 9.8 per fish infected. The prevalence was most high in Squalidus spp. (97.7%) and followed by acheilognathinid fish (66.8%), Pungtungia herzi (52.0%), rasborinid fish (39.6%) and Hemibarbus spp. (25.9%) from Yangcheon. The intensity was also most high in Squalidus spp. (27.0). The endemicity with CcMc was very low in fishes from water systems of Nakdong-gang in the east coast of Korea. Conclusively, it is confirmed that various fish species act as the second intermediate hosts of C. complanatum, and the endemicities of CcMc are more or less different by the fish species and group from Yangcheon, in Sancheong-gun, Gyeongsangnam-do, Korea.

• Parasites, Hosts and Diseases
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• 제58권6호
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• pp.635-645
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• 2020

Morphological and molecular characterization of clinostomid metacercariae (CMc) was performed with the specimens collected in fish from Korea and Myanmar. Total 6 batches of clinostomid specimens by the fish species and geographical localities, 5 Korean and 1 Myanmar isolates, were analyzed with morphological (light microscopy and SEM) and molecular methods (the cytochrome c oxidase 1 gene and internal transcribed spacer 1/5.8S rRNA sequence). There were some morphological variations among CMc specimens from Korea. However, some morphometrics, i.e., the size of worm body and each organ, ratio of body length to body width, and morphology of cecal lumens, were considerably different between the specimens from Korea and Myanmar. The surface ultrastructures were somewhat different between the specimens from Korea and Myanmar. The CO1 sequences of 5 Korean specimens ranging 728-736 bp showed 99.6-100% identity with Clinostomum complanatum (GenBank no. KM923964). They also showed 99.9-100% identity with C. complanatum (FJ609420) in the ITS1 sequences ranging 692-698 bp. Meanwhile, the ITS1 sequences of Myanmar specimen showed 99.9% identity with Euclinostomum heterostomum (KY312847). Five sequences from Korean specimens clustered with the C. complanatum genes, but not clustered with Myanmar specimens. Conclusively, it was confirmed that CMc from Korea were morphologically and molecularly identical with C. complanatum and those from Myanmar were E. heterostomum.