• Title/Summary/Keyword: Clinical statistics

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Maximum Tolerated Dose Estimation by Stopping Rule and SM3 Design in a Phase I Clinical Trial (제 1상 임상시험에서 멈춤 규칙과 SM3 디자인을 이용한 최대허용용량 추정법)

  • Kim, Byoungchan;Kim, Dongjae
    • The Korean Journal of Applied Statistics
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    • v.27 no.1
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    • pp.13-20
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    • 2014
  • Phase I Clinical Trials estimate a Maximum Tolerated Dose(MTD). In this paper, an MTD estimation method applied stopping rule is proposed for Phase I Clinical Trials. The suggested MTD estimation method is compared to the Continual Reassessment Method(CRM) method using a Monte Carlo simulation study.

Department of Statistics, Chonnam National University (임상시험을 위한 Case Report Form의 설계)

  • Park, Eun-Sik
    • Korean Journal of Clinical Pharmacy
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    • v.16 no.1
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    • pp.40-45
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    • 2006
  • In clinical trials, it is important to have well designed case report forms (CRF) in order to obtain good quality of data. If CRF design at the first stage of your study goes wrong, after all efforts have been made, you may find practical difficulties in data analysis at the final stage of your study because of incomplete or wrong information. In this paper, the following rules fundamental to CRF design are introduced: rules in general, rules of format or style, categorized responses, forms with multiple records per subject, and international studies. Investigators are well aware of research goals, however sometimes they do not know how to express it on CRF. If they understand the rules fundamental to CRF design, time for CRF development will be saved and CRF completeness will be enhanced.

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Stress, Anxiety and Fatigue of Nursing Students in Clinical Practice (일 간호학생의 임상실습 스트레스, 불안 및 피로조사)

  • Kim, Chang-Sook;Kim, Ran;Kim, Young-Jae;Park, Myung-Hee;Park, In-Soon
    • The Journal of Korean Academic Society of Nursing Education
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    • v.11 no.2
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    • pp.151-160
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    • 2005
  • Purpose: The purpose of this study was to identify the levels of stress, anxiety and fatigue of nursing students in clinical practice, and the relationship among these variables. Method: Data was collected by structured questionnaires from 223 nursing students who have practiced at the hospital in Gwangju. Data was analyzed by using descriptive statistics, ANOVA, t-test and Pearson's correlation coefficient. Result: The mean score for stress was 3.87. The mean score for anxiety was 44.88. The mean score for fatigue was 30.79. There was a significant difference of stress according to student grade, practice unit, practice time, satisfaction of clinical practice. There was a significant difference of anxiety according to religion, health status, satisfaction of clinical practice, satisfaction on nursing. There was a significant difference of fatigue according to religion, health status, practice time, satisfaction of clinical practice, selective motivation on nursing, satisfaction on nursing. Conclusion: This study revealed that there was a significant correlation among stress, anxiety and fatigue of nursing students in clinical practice.

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Effect of Ego-Resilience of Nursing Students on Clinical Practice Competency: Focus on the Mediating Effects of Critical Thinking Dispositions (간호대학생의 자아탄력성이 임상수행 능력에 미치는 영향: 비판적 사고성향의 매개효과를 중심으로)

  • Song, Eun Ju;Park, Sook Kyoung
    • Journal of Korean Public Health Nursing
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    • v.34 no.1
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    • pp.60-73
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    • 2020
  • Purpose: The purpose of this study was to determine the mediating effect of critical thinking dispositions in the relationship between ego-resilience and clinical practice competency. Method: This study used a descriptive design with a survey method. A total of 193 nursing students were recruited from 4 colleges of nursing in C city, and A and B province in Korea. The data was collected using questionnaires from October 6, 2017 to October 24, 2017. The data was analyzed using descriptive statistics, independent t-tests, one-way ANOVA, Pearson correlation analysis, and linear regression analysis. Result: There were showed significant positive relationships of clinical practice competency with ego-resilience. In addition, critical thinking dispositions had a partial mediating role in the relationship between ego-resilience and clinical practice competency. Conclusion: This study identified the mediating effects of critical thinking dispositions and how to improve clinical practice competency. The results of this study can be used as basic data for establishing an educational approach to enhance clinical practice competency, which is considered a key competency for nursing college students.

The Effect of Clinical Performance Improving by Application of Core Skill-TLP (Core Skill-TLP가 임상수행능력 향상에 미치는 효과)

  • Hwang, Hyun-Sook
    • Journal of the Korean Society of Physical Medicine
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    • v.7 no.2
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    • pp.231-239
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    • 2012
  • Purpose : The purpose of this study is to investigate the effect of clinical performance improved by the application of the Core-Skill TLP to students. Methods : The subject of the study were 48 students who are enrolled in the 2nd semester of the 3rd year in the department of physical therapy. In order to compare the difference in physical examination and intervention, clinical practice integration as well as interpersonal communication skills were measured before and after clinical performance experiments by using the questionnaire. Result : The results are as follows. There was an improvement after examination & intervention about mean 1.52(t=16.928, p=.000), in clinical practice integration 1.30(t=14.541, p=.000) and in interpersonal communication skills 0.86(t=9.510, p=.000). It shows the significant difference in statistics. Conclusion : According to these results, the Core-Skill TLP is proved as a good learning strategy and could be strongly recommended since it significantly improved physical examination & intervention, clinical practice integration and interpersonal communication skills.

Effects of Clinical Decision-making on Job Satisfaction among Pediatric Nurses: The Mediating Effect of the Nurse-Parent Partnership (아동병동 간호사의 임상의사결정 능력이 직무만족도에 미치는 효과: 아동병동 간호사-환아 부모 간 파트너십 매개효과를 중심으로)

  • Shin, Kyoung-Suk;Kim, Hye-Young
    • Child Health Nursing Research
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    • v.24 no.1
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    • pp.9-17
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    • 2018
  • Purpose: The purpose of this descriptive survey study was to characterize the relationship between clinical decision-making and job satisfaction among pediatric nurses and to elucidate the mediating effects of the nurse-parent partnership on that relationship. Methods: The subjects of the study were 174 nurses who had worked in a pediatric ward in a university hospital, general hospital, or children's hospital. Data were collected from June 20, 2016 to August 10, 2016 and analysed using descriptive statistics, the t-test, analysis of variance, the Pearson correlation coefficient, and three-step mediated regression analysis in SPSS version 22.0 for Windows. Results: The nurse-parent partnership had significant effects on clinical decision-making and job satisfaction, with an explanatory power of 19% and 26%, respectively. The nurse-parent partnership had a partial mediating effect on the relationship between clinical decision-making and job satisfaction (Sobel test: Z=4.31, p<.001). Conclusion: The nurse-parent partnership had a partial mediating effect on the relationship between clinical decision-making and job satisfaction among pediatric nurses. Therefore, in order to improve the job satisfaction of pediatric nurses, it is necessary to develop effective educational programs and strategies to address their clinical decision-making and their experiences of the nurse-parent partnership.

The Relationship of Clinical Competency and Self-directed Learning in Nursing Students (간호학생의 임상수행능력과 자기주도적 학습의 관계)

  • Yang, Jin-Ju;Park, Mi-Young
    • The Journal of Korean Academic Society of Nursing Education
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    • v.10 no.2
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    • pp.271-277
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    • 2004
  • Purpose: The purpose of this study was to identify the relationship of clinical competency and self-directed learning in nursing students. Method: This study was conducted at two nursing colleges with students in a 2 year undergraduate nursing program. Data were collected from 182 students by means of self reporting questionnaires from October 1 to October 8, 2004. The data were analyzed by SPSS 10.0 PC programs using descriptive statistics, one-way ANOVA, Pearson correlation coefficient. Result: The questionnaire of students' clinical competency consisted of nineteen items based on a five point summated rating scale and was categorized into six subscales by factor analysis. The six subscales are nursing process, major nursing intervention, education for clients, observation and physical examination, and fundamental nursing. The more adaptable to major, the higher clinical competency (F= 3.406, p= .035) and self-directed learning (F= 7.444, p= .001). There was a positive correlation between students' clinical competency and self-directed learning (r= .367, p= .001). Conclusion: we concluded that future research should explore strategies for the development of self-directed learning to improve clinical competency of nursing students.

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A Comparison between the Contamination Level of Uniforms and the Nasal Staphylococcus aureus Colonization before and after the Clinical Practice of Nursing Students (간호대학생의 실습 전후 실습복 오염도 및 비강내 황색포도알균 집락정도 비교)

  • Park, Jin Hee;Shin, Gisoo;Kim, Jiyoung
    • Journal of Korean Biological Nursing Science
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    • v.16 no.2
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    • pp.90-97
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    • 2014
  • Purpose: The purpose of this study was to compare the contamination level of uniforms with nasal colonization of Staphylococcus aureus before and after the clinical practice of nursing students. Methods: This study was a survey research, conducting microbial culture by smearing the front surface and the pockets of uniforms, and the nasal cavity both before and after clinical practice on 70 nursing students. For the analysis, descriptive statistics, chi-square test, paired t-test were used for statistical analysis using SPSS 19.0. Results: The contamination level of uniforms increased more significantly after clinical practice on the front surface (p=.008) and pockets (p=.031) than before clinical practice, and Staphylococcus aureus, and Enterobacter aerogenes were detected. Conclusion: Through the results above, it is believed that it is reasonable to do the laundering of clinical uniforms of nursing students once a week. Because it is possible to disseminate disease germs with the contamination of clinical practice uniforms in a hospital environment, it is necessary to offer education for the laundering of uniforms with appropriate management.

The Mediating Effect of Resilience on the Relationship between Emotional Labor and Happiness of Clinical Nurses (임상간호사의 감정노동과 행복감의 관계에서 회복탄력성의 매개효과)

  • Kim, Hyun-Ji;Choi, Hyunkyung
    • Korean Journal of Occupational Health Nursing
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    • v.26 no.1
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    • pp.40-46
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    • 2017
  • Purpose: The purpose of this study was to investigate the mediating effect of resilience on the relationship between emotional labor and happiness of clinical nurses. Methods: A descriptive, cross-sectional study was conducted with 224 clinical nurses who had one or more years of clinical experiences from four general hospitals in D city in Korea. Data collected from the survey using self-reported questionnaires were analyzed by t-test, one-way ANOVA, Pearson's correlation coefficients, and multiple regression analysis using IBM SPSS statistics 21.0 program. Results: There were statistically significant correlations among variables; a negative correlation between happiness and emotional labor, a positive correlation between happiness and resilience, and a negative correlation between emotional labor and resilience. Meanwhile, resilience had a partial mediating effect on the relationship between emotional labor and happiness. That is, resilience can play an important role between emotional labor and happiness of clinical nurses as a mediator. Conclusion: Considering the findings of this study, developing programs that can improve resilience of clinical nurses who experience emotional labor are needed to increase their level of happiness.