• 제목/요약/키워드: Clinical pathology

검색결과 3,994건 처리시간 0.029초

A clear cell hepatocellular carcinoma in an obese dog with hyperlipidemia: a case report

  • Jung, Jae-Ha;Lee, MaRo;Yang, Yeseul;Seo, Dansong;Hwang, Sung-Hyun;Kim, Wan Hee;Kim, Yongbaek
    • 대한수의학회지
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    • 제61권4호
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    • pp.34.1-34.4
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    • 2021
  • An 11-year-old obese dog was referred for a liver mass. Cytologic examination revealed vacuolated hepatocytes with mild pleomorphism. A partial liver lobectomy was performed. On histopathologic examination, the mass was diagnosed as hepatocellular carcinoma composed of hepatocytes with clear vacuoles. These findings were consistent with clear cell hepatocellular carcinoma (CCHCC). The CCHCC is a rare subtype of hepatocellular carcinoma in dogs, and clinical features are poorly defined. This is the first report on the cytological, histological and clinical aspects of CCHCC, suggesting that obesity and hyperlipidemia are potential risk factors for CCHCC in dogs.

Isolation Rate of Methicillin-Resistant Staphylococcus aureus (MRSA) from Nasal cavity inferior regions and Cellular phones

  • Kim, Chung Hwan;Lee, Jun Young;Kim, Mi Kyeong;Kim, Sung Hwan;Park, Geun Young;Bae, So Yeon;Seo, Myeong Jin;Go, In Hyeog
    • 대한임상검사과학회지
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    • 제44권3호
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    • pp.118-123
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    • 2012
  • Nosocomial infection and community-acquired infection with Staphylococcus aureus, especially methicillin-resistant S. aureus (MRSA), has become a strong concern in human body sites and related effects. The aim of this study is investigate the isolation rate of MRSA from nasal cavity inferior regions and cellular phones to assess the risk factor of nosocomial infection and community-acquired infection. 34.7% and 37.2% isolates were MRSA from the nasal cavity inferior regions and cellular phones according to a Mannitol salt agar (added oxacillin $6{\mu}g/mL$) culture and PCR according to S. aureus specific 16S rRNA and mecA primers. Thus, the distribution of S. aureus and the isolation rate of MRSA represent a very high risk factor regards nosocomial infection and community-acquired infection.

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임상병리학, 검사의학, 의료생물학 관련 지원보건직 명칭에 대한 제안 (Job Title Recommendations for Allied Health Professionals Related to Clinical Pathology, Laboratory Medicine, and Medical Biology)

  • 구본경;임대진;김상원;김철
    • 대한임상검사과학회지
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    • 제55권1호
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    • pp.1-8
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    • 2023
  • 본 연구의 목적은 임상병리사의 전공과 직업에 정체성을 부여할 수 있는 용어를 찾는 것이다. 임상병리학이라는 용어는 병리학의 모든 분야, 즉 해부병리학, 화학병리학, 혈액학, 미생물학 및 이들의 모든 하위 전문 분야를 포함하도록 의도되었다. 불행히도, 많은 나라에서 임상병리학이라는 용어는 해부병리학을 배제하는 것으로 생각되었는데, 이는 이름이 영어 이외의 언어로 번역되었을 때 문제가 복잡해졌다. 임상병리학(미국, 영국)은 의학의 한 전문 분야이다. 유사한 용어로는 검사의학(독일, 폴란드), 의료/임상생물학(프랑스, 네덜란드) 또는 임상분석학(스페인)이 있다. 의료기술은 개인, 회사 및 기관과 같이 질문하는 사람에 따라 약간 다르게 정의된다. 물론, 질문하는 언어에 따라 다르다. 의료기술은 임상검사기술학, 지원보건과학, 의료기기, 의생명공학, 보건기술로도 번역될 수 있다. 지원보건과학에서는 '임상병리기술학·병리기술학'이라는 용어를 사용하지 않는다. '보건계열 임상병리학 및 임상병리사'의 명칭은 '의생명검험과학·의생명검험사' 또는 '임상검사분석학·임상검사분석사'로 대체할 수 있다. 본 연구에서는 학문과 자격의 명칭을 '의생명'이 결합된 용어로 '의료생물학·의료생물사'로 변경할 것을 제안해 본다.

Species Identification of Nontuberculous Mycobacteria (NTM) by PCR-Restriction Fragment Length Polymorphism (PRA) of the rpoB Gene from Three Hospitals of Busan-Kyeongnam Area

  • Choi, Sung-Ran;Kang, Min-Jung;Park, Gyu-Hwan;Kim, Da-Hye;Jeong, Da-Woon;Seo, Eun-Hye;Lee, Hyang-Min;Park, Hyun-Kyung;Jeong, Jin-Yee;Lee, Jung-Min;Jeong, Soo-Young;Lee, Jun-Young;Cho, Eun-Jin;Jekal, Suk;Kim, Chung-Hwan
    • 대한임상검사과학회지
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    • 제45권2호
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    • pp.48-53
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    • 2013
  • Recently, the isolation rate of nontuberculous mycobacteria (NTM) in clinical laboratories and the incidence of NTM infections are on the increase in Korea, but there have been only a few studies that reveal the general aspect of NTM isolation or species distribution. Therefore, this study was performed to examine the species identification by PCR-restriction fragment length polymorphism analysis (PRA, PCR-RFLP), and the clinical significance of mycobacterial cultures. PRA was used during the novel region of the rpoB gene and was developed for rapid and precise identification of mycobacteria to the species level. From January 2012 to April 2012, we examined pre-identified nontuberculous mycobacteria (60 species in 3 hospital of Busan-Kyeongnam area). We confirmed 4 (6.6%) Mycobacterium tuberculosis (MTB) and 56 (93.4%) NTM from 60 pre-identified NTM species by multiplex PCR (MolecuTech $MTB-ID^R$ V3, YD Diagnostics, Korea) and PRA (Myco-ID, YD Diagnostics, Korea). The distribution of 56 NTM species were M. intracellulare type I 15 (26.7%), M. avium 14 (25%), M. abscessus 11 (19.5%), M. kansasii type I 3 (5.4%), M. pulveris 2 (3.6%), M. intracellulare type, M. chelonae, M. kansasii type V, M. gallinarum, M. wolinskyi. Respectively, 1 (1.8%) and 6 (10.7%) species were not identified.

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Phenotypic and Genotypic Detection of Metallo-β-Lactamase Producing Pseudomonas aeruginosa

  • Yang, Byoung-Seon;Hong, Keun-Seok;Jung, Seung-Bong;Kwon, Young-Hoon;Jeong, Jong-Yoon;Lee, Min-Joo;Lee, Hye-In;Park, Mi-Seon;Choi, Seung-Gu
    • 대한임상검사과학회지
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    • 제44권2호
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    • pp.81-85
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    • 2012
  • This study was undertaken to evaluate phenotypic and genotypic methods for detection of Metallo-Beta-Lactamases (MBLs) among nosocomial Pseudomonas aeruginosa. Of the 50 P. aeruginosa isolates from clinical specimens, 20 were evaluated for carbapenem resistance and screened for MBL by double-disk synergy test and combined-disk test. Nineteen strains (95%) were found to be MBL producers among the 20 P. aeruginosa. MBL positives were further confirmed by Polymerase Chain Reaction (PCR). For the IMP and VIM types of MBLs, PCR analysis was performed on 19 of the 20, and 10 were positive for VIM MBL type. This study reports the validation of a simple and accurate MBL detection method that can be easily incorporated into the daily routine of a clinical laboratory. Early detection of MBL-carrying organisms, including those with susceptibility to carbapenems, is of paramount clinical importance, as it allows rapid initiation of strict infection control practices as well as therapeutic guidance for confirmed infection.Key Words : Hepatitis A virus (HAV), Anti-HAV, Hospital workers, Prevalence, Vaccination

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