• 제목/요약/키워드: Clinical outcome

검색결과 3,182건 처리시간 0.039초

Effectiveness after Designation of a Trauma Center: Experience with Operating a Trauma Team at a Private Hospital

  • Kim, Kyoung Hwan;Han, Sung Ho;Chon, Soon-Ho;Kim, Joongsuck;Kwon, Oh Sang;Lee, Min Koo;Lee, Hohyoung
    • Journal of Trauma and Injury
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    • 제32권1호
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    • pp.1-7
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    • 2019
  • Purpose: The present study aimed to evaluate the influence of how the trauma care system applied on the management of trauma patient within the region. Methods: We divided the patients in a pre-trauma system group and a post-trauma system group according to the time when we began to apply the trauma care system in the Halla Hospital after designation of a trauma center. We compared annual general characteristics, injury severity score, the average numbers of the major trauma patients, clinical outcomes of the emergency department, and mortality rates between the two groups. Results: No significant differences were found in the annual patients' average age ($54.1{\pm}20.0$ vs. $52.8{\pm}18.2$, p=0.201), transportation pathways (p=0.462), injury mechanism (p=0.486), injury severity score (22.93 vs. 23.96, p=0.877), emergency room (ER) stay in minutes (199.17 vs. 194.29, p=0.935), time to operation or procedure in minutes (154.07 vs. 142.1, p=0.767), time interval to intensive care unit (ICU) in minutes (219.54 vs. 237.13, p=0.662). The W score and Z score indicated better outcomes in post-trauma system group than in pre-trauma system group (W scores, 2.186 vs. 2.027; Z scores, 2.189 vs. 1.928). However, when analyzing survival rates for each department, in the neurosurgery department, in comparison with W score and Z score, both W score were positive and Z core was higher than +1.96. (pre-trauma group: 3.426, 2.335 vs. post-trauma group: 4.17, 1.967). In other than the neurosurgery department, W score was positive after selection, but Z score was less than +1.96, which is not a meaningful outcome of treatment (pre-trauma group: -0.358, -0.271 vs. post-trauma group: 1.071, 0.958). Conclusions: There were significant increases in patient numbers and improvement in survival rate after the introduction of the trauma system. However, there were no remarkable change in ER stay, time to ICU admission, time interval to emergent procedure or operation, and survival rates except neurosurgery. To achieve meaningful survival rates and the result of the rise of the trauma index, we will need to secure sufficient manpower, including specialists in various surgical area as well as rapid establishment of the trauma center.

주의력결핍과잉행동 장애아동을 대상으로 제공되는 국내 중재에 대한 고찰 연구 (Effects of Therapeutic Interventions for Children With Attention Deficit Hyperactivity Disorder: A Systematic Review)

  • 박영주;김은주
    • 대한감각통합치료학회지
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    • 제17권1호
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    • pp.43-53
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    • 2019
  • 목적 : 본 연구는 주의력결핍과잉행동장애아동(Attention Deficit Hyperactivity disorder; ADHD)을 대상으로 국내에서 제공되는 중재 방법을 체계적으로 고찰하여 최신의 국내 치료 경향을 제시하고자 하였다. 연구방법 : 2004년 1월부터 2018년 12월까지 최근 15년간 국내 학회지에 게재된 연구를 대상으로 하였다. 누리미디어(DBpia), 스콜라(Scholar), 학술연구정보서비스(RISS), 한국학술정보(KISS)에서 '주의력결핍과잉행동', '아동', '중재'를 키워드로 검색하였다. 연구대상으로 선정된 연구는 총 14개로, 각 연구는 근거의 질적 수준과 방법론적 질적 수준으로 분석한 후 그 결과를 대상자, 중재, 대조, 결과의 순으로 제시하였다. 결과 : 분석 결과 근거기반 실행의 질적 수준은 수준 IV의 연구가 가장 많았고, 방법론적 질적 수준은 '보통'의 연구가 가장 많았다. 중재는 상호작용식 메트로놈 중재(Interactive metronome; IM)의 빈도가 가장 높았고, 측정된 평가도구는 상호작용식 메트로놈 전체형 검사(Long form assessment of IM), 아동 청소년 행동평가척도(Korean behavior child checklist; K-CBCL)의 사용이 높았다. 중재결과 ADHD아동의 집중력, 과잉행동, 과제 수행, 과다언어 사용, 그리고 타이밍 등에서 유의한 효과가 나타났다. 결론 : 국내 ADHD아동을 대상으로 다양한 중재방법이 제공되었고, 그 결과 ADHD증상에서 효과적인 결과가 나타났다. 따라서 본 연구결과는 임상에서 근거기반 실행을 위한 기초자료로 사용할 수 있다. 앞으로 ADHD아동을 대상으로 한 지속적인 연구가 이루어져야 할 것이다.

변형-내초점 핀 고정술을 이용한 골성 망치 수지의 해부학적 직접 정복 (Anatomical Direct Reduction of Bony Mallet Finger Using Modified-Intrafocal Pinning Technique)

  • 강상우;박지강;정호승;차정권;김국종
    • Archives of Hand and Microsurgery
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    • 제23권4호
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    • pp.248-253
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    • 2018
  • 목적: 변형-내초점 핀 고정술을 통한 골성 망치 수지의 해부학적인 직접 정복에 대한 임상적 결과를 알아보고자 한다. 방법: 2014년 3월부터 2017년 10월까지 18명의 골성 망치 수지 환자를 대상으로 K-강선을 이용하여 골편을 직접 정복하는 방법인 변형-내초점 핀 고정술을 시행하였다. 수술 후 통증, 관절 운동 범위, 방사선적인 평가를 시행하였다. 또한 골유합 시기, 기능 회복 정도, 합병증 발생률을 평가하였고, 수술 후 기능적 예후를 판정하기 위해 Crawford의 평가 기준을 이용하였다. 결과: 평균 6주(5-7주)에 방사선적 골유합을 얻었다. 전체 환자에서 평균 $2.8^{\circ}$ ($0^{\circ}-10^{\circ}$)의 신전 소실(extension loss)이 발생하였다. 모든 환자에서 관절면의 일치와 만족스러운 관절면의 재형성이 관찰되었으며, 최종 외래 추시에서 원위지간 관절의 평균 굴곡각은 $72.2^{\circ}$ ($70^{\circ}-75^{\circ}$)였다. Crawford의 평가 기준으로 아주 만족이 12명(66.7%), 만족이 6명(33.3%)이었다. 결론: 변형-내초점 핀 고정술은 골편을 직접 정복 후 고정하여 해부학적 정복을 얻는 방법으로 기존의 다른 경피적 핀 고정술들과 결합하여 적절한 적응증에 적용한다면 좋은 결과를 얻을 수 있을 것으로 기대한다.

불면장애에 대한 천왕보심단의 체계적 문헌 고찰 및 메타분석 연구 (Herbal Medicine (Cheonwangbosim-Dan, Tianwangbuxin-Pellet) for Insomnia Disorder: A Systematic Review and Meta-Analysis of Randomized Controlled Trials)

  • 사공종원;김동희;하지원;조윤송;김보경
    • 동의신경정신과학회지
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    • 제29권4호
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    • pp.267-280
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    • 2018
  • Objectives: The objective of this study was to provide clinical evidence to support the use of a herbal medicine (Cheonwangbosim-Dan/Tianwangbuxin-Pellet (TWBXP)) for insomnia. Methods: Randomized controlled trials that verified effects of Herbal Medicine (Cheonwangbosim-Dan, Tianwangbuxin-Pellet) treating primary insomnia were carried out. A literature search of English, Chinese, Korean databases was also performed. The selected literature were assessed by Risk of Bias (RoB). Results: The total number of selected trials was 13 RCTs. Among the 13 RCTs, 10 were meta-analyzed. The Chinese Classification of Mental Disorders-3 (CCMD-3) was frequently used as the diagnostic criteria for interventions during the analysis of the use of herbal medicine (Cheonwangbosim-Dan/Tianwangbuxin-Pellet) for management of primary insomnia. As for outcome measurement, the effective rate was used. From the Meta-analysis of the studies, it was established that the insomnia cure effective rate in the TWBXP group was higher than that in the Western Medicine (WM) group (RR: 1.15, 95% CI: 1.07 to 1.24, p<0.0001, $I^2=33%$). Also, the effective rate in the TWBXP+ACU group was significantly different compared to the WM group (RR: 1.32, 95% CI: 1.13 to 1.54, p=0.0004, $I^2=0%$). The quality of the selected RCTs was low. Conclusions: Herbal medicine (Cheonwangbosim-Dan/Tianwangbuxin-Pellet) is effective for treating primary insomnia. It is worth noting that this studies were of relatively poor quality. The sample sizes were also small. Therefore, further investigations into the diagnosis and treatment of insomnia are warranted.

고투명도 입방정상 지르코니아(5Y-PSZ) 라미네이트를 이용한 왜소치의 비침습적 심미 수복 증례 (A noninvasive esthetic treatment of isolated microdontia using new high-translucent cubic-phase zirconia (5Y-PSZ) laminate veneers: A case report)

  • 안민진;안도관;표세욱;김희경
    • 대한치과보철학회지
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    • 제57권3호
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    • pp.263-270
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    • 2019
  • 치아수복의 최신 경향은 심미적인 개선과 건강한 치아 조직의 유지에 중점을 둔 보존적 심미 치료이다. 본 증례에서는 디지털 워크플로우를 사용하여 왜소치 환자에서 고투명도 입방정상 지르코니아(5Y-PSZ) 라미네이트를 이용한 비침습적 심미 치료의 성공적인 결과를 보고하고 임상적 의의를 평가하였다. 왜소치의 가족력이 있는 15세 여자 환자가 상악 전치부의 심미적 개선을 주소로 아주대학교 치과병원을 내원하였다. 별도의 치아 삭제 없이 디지털 인상 및 캐드캠 시스템을 통해 적절한 출현윤곽을 고려한 고투명도 입방정상 지르코니아(5Y-PSZ) 라미네이트를 제작하여 상악 6전치를 수복하였다. 최종 수복물 장착 6개월 후, 기계적 및 생물학적 합병증은 발견되지 않았으며 기능 및 심미적으로 만족스러운 결과를 보였다. 지르코니아의 치주 조직 친화성 및 개선된 투명도로 입방정상 지르코니아(5Y-PSZ)는 비침습적 심미보철 재료로 고려될 수 있다.

Triangular Resection of the Upper Lateral Cartilage for Middle Vault Deviation

  • Ryu, Gwanghui;Seo, Min Young;Lee, Kyung Eun;Hong, Sang Duk;Chung, Seung-Kyu;Dhong, Hun-Jong;Kim, Hyo Yeol
    • Clinical and Experimental Otorhinolaryngology
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    • 제11권4호
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    • pp.275-280
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    • 2018
  • Objectives. Middle vault deviation has a significant effect on the aesthetic and functional aspects of the nose, and its management continues to be a challenge. Spreader graft and its modification techniques have been focused, but there has been scarce consideration for removing surplus portion and balancing the upper lateral cartilage (ULC). This study aimed to report the newly invented triangular-shaped resection technique ("triangular resection") of the ULC and to evaluate its efficacy for correcting middle vault deviation. Methods. A retrospective study included 17 consecutive patients who presented with middle vault deviation and underwent septorhinoplasty by using triangular resection at a tertiary academic hospital from February 2014 and March 2016. Their outcomes were evaluated pre- and postoperatively including medical photographs, acoustic rhinometry and subjective nasal obstruction using a 7-point Likert scale. Results. The immediate outcomes were evaluated around 1 month after surgery, and long-term outcomes were available in 12 patients; the mean follow-up period was 9.1 months. Nasal tip deviation angle was reduced from $5.66^{\circ}$ to $2.37^{\circ}$ immediately (P<0.001). Middle vault deviation also improved from $169.50^{\circ}$ to $177.24^{\circ}$ (P<0.001). Long-term results were $2.49^{\circ}$ (P=0.015) for nasal tip deviation and $178.68^{\circ}$ (P=0.002) for middle vault deviation. The aesthetic outcome involved a complete correction in eight patients (47.1%), a minimally visible deviation in seven patients (41.2%) and a remaining residual deviation in two patients (11.8%). Pre- and postoperative minimal cross-sectional areas (summation of the right and left sides) were 0.86 and 1.07, respectively (P=0.021). Fifteen patients answered about their nasal obstruction symptoms and the median symptom score had alleviated from 6.0 to 3.0 (P=0.004). Conclusion. Triangular resection of the ULC is a simple and effective method for correcting middle vault deviation and balancing the ULCs without complications as internal nasal valve narrowing.

일차성 만성불면증 환자에서 경두개 직류전기자극법 치료 효과: 개념 증명 연구 (Effects of Transcranial Direct-Current Stimulation Therapy on Primary Chronic Insomnia: A Proof-of Concept Clinical Trial)

  • 전진선;김태준;구선아;박지숙;김근태;양태원;임정아;변정익;선우준상;정기영
    • Journal of Sleep Medicine
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    • 제15권2호
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    • pp.37-42
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    • 2018
  • Objectives: To assess the effect and safety of transcranial direct-current stimulation (tDCS) in primary chronic insomnia. Methods: A one-month, double-blind, randomized, sham-controlled trial was performed. A total of 7 patients with primary chronic insomnia received tDCS using anodal (n=3), cathodal (n=2), or sham stimulation (n=2). They were followed up at 1 week and 1 month after treatment. The primary outcome measures included improvement in total sleep time (TST), sleep latency (SL), and sleep efficiency (SE) at 1 month follow-up. Results: TST and SE were improved with tDCS at 1 month follow-up in all patients (100%) of the anodal group, one (50%) of the cathodal group, and one (50%) of the sham group. tDCS improved SL at 1 month follow-up in two patients (67%) of the anodal group, one (50%) of the cathodal group, and none (0%) of the sham group. With respect to adverse events, transient itching sensation occurred in one patient of the anodal group. None of the other groups reported adverse events. Conclusions: Our results suggest that tDCS may be effective and safe for treatment of primary chronic insomnia. A larger controlled study needs to be further investigated.

접착치의학 개념에 따른 최소 침습적 치아 삭제법을 적용한 심미적인 치은 연상 변연 도재 부분피개관 수복 증례 (Clinical performance of esthetic ceramic partial-coverage restorations with supra-gingival margin using minimally invasive tooth preparation method according to the concept of adhesive dentistry)

  • 홍명식;최유성;이종혁;하승룡
    • 대한치과보철학회지
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    • 제59권3호
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    • pp.319-332
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    • 2021
  • 심미적인 도재 재료와 레진 시멘트의 비약적인 발전으로 임상에서 금속도재관에서 전부도재관으로의 전환이 활발히 이루어지고 있으며, 도재 수복물 제작 시 그에 적합한 형태와 기술을 이용하여야 그 장점을 최대화할 수 있다. 최근 법랑질을 최대한 보존하고 접착 효율을 높이는 최소 침습적 치아 삭제법을 적용하여 치은 연상 변연을 가진 심미적인 도재 부분피 개관 수복방법이 소개되었는데, 이를 통해 치질 삭제의 최소화, 시멘트 제거의 용이성 등 여러 장점들을 얻을 수 있다고 보고된다. 또한 이 제작법은 치은 압배사의 삽입이 불필요하여 치은 압배사 삽입에 소요되는 시간을 절약할 수 있으며 환자의 불편감도 감소시킬 수 있다. 더 나아가 치은 열구액이나 혈액의 개입 없이 명확하게 변연을 채득할 수 있어 더 정확한 수복물 제작이 가능하다고 보고된다. 본 증례에서는 각각 해당 치아 부위에 부분적인 결함이 있는 환자에서 통상적인 전부피개관이 아닌 접착치의학 개념에 따른 최소 침습적 치아 삭제법을 적용한 치은 연상 변연 도재 부분피개관으로 다양한 제작 방법을 활용하여 수복함으로써 불필요한 치아 삭제를 방지하고 잔존 치질을 최대한 보존할 수 있었다. 치료 후 환자와 술자 모두 심미적, 기능적으로 만족할 만한 결과를 얻었기에 이를 보고하는 바이다.

Fibrinolysis with Lower Dose Urokinase in Patients with Complicated Parapneumonic Effusion

  • Lee, Seul;Lee, Heock;Lee, Dong Hyun;Kang, Bo Hyoung;Roh, Mee Sook;Son, Choohee;Kim, Sung Hyun;Lee, Hyun-Kyung;Um, Soo-Jung
    • Tuberculosis and Respiratory Diseases
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    • 제84권2호
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    • pp.134-139
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    • 2021
  • Background: Intrapleural urokinase is one of the most widely used fibrinolytic agents in the treatment of complicated parapneumonic effusion (CPPE). However, little research has been performed on the optimal urokinase dosage. The aim of this study was to evaluate the treatment efficacy of half dose urokinase compared with conventional dose urokinase. Methods: We retrospectively enrolled 92 patients with CPPE or empyema who underwent intrapleural urokinase treatment at two tertiary hospitals. Patients received antibiotics, chest tube drainage, and other treatments as part of routine care. The primary outcome was the treatment success rate in the half dose urokinase group (50,000 IU daily for maximal 6 days) and the conventional dose urokinase group (100,000 IU daily). Treatment success was defined as clinical and radiological improvements without surgical treatment or re-admission within one month. Results: Forty-four patients received half dose urokinase, whereas 48 patients were treated with conventional dose urokinase. Both groups were relatively well matched at baseline, excluding higher serum white blood cell count and higher empyema prevalence in the half dose urokinase group. The treatment success rate was not different between the two groups (p=0.048). There were no differences in the rate of in-hospital death and surgical treatment, hospitalization duration, and indwelling catheter duration. In the multivariate analysis, urokinase dose was not a predictor of treatment success. Conclusion: Half dose intrapleural urokinase is equally effective conventional dose urokinase in treating patients with CPPE or empyema.

상담자 요소가 이명재훈련치료의 효과에 미치는 영향 (The Effect of Different Counselors on Treatment Outcome of Tinnitus Retraining Therapy)

  • 김우진;공지선;박소영;정기환;김래형;여상원;박시내
    • Korean Journal of Otorhinolaryngology-Head and Neck Surgery
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    • 제60권5호
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    • pp.209-214
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    • 2017
  • Background and Objectives Tinnitus retraining therapy (TRT) is one of the most effective treatment modalities of tinnitus based on the neurophysiological model proposed by Jastreboff and Hazell. This study was performed to evaluate the effect of counselor factor on treatment outcomes of TRT. Subjects and Method The total of 78 patients who had TRT from three different counselors in a tinnitus clinic of tertiary referral center from Jan 2015 to Dec 2015 were included in this study. Their medical records were retrospectively reviewed to evaluate the therapeutic response to TRT. Results Among 78 patients who were followed-up for more than 6 months, 47, 20, and 11 patients were treated by counselors A, B, C (all ENT specialists), respectively. Counselor A had 15-year-experience of TRT counseling, whereas counselor B and C were well trained but beginners of TRT counseling. Initial clinical characteristics including Tinnitus Handicap Inventory (THI) and tinnitus Visual Analogue Scale (VAS) scores of the patients among three groups were not significantly different. Treatment responses evaluated via THI and most of the tinnitus VAS scores after at least 6 months after TRT were significantly improved in all three groups (p<0.05) with no significant difference between the senior (A) and junior (B, C) group. Conclusion TRT seems to be an effective treatment modality of tinnitus even in this short term follow-up study. Treatment outcomes of TRT may not depend on the counselors once they are well trained and follow the same protocol.