• Herbal Formula Science
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• v.32 no.3
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• pp.325-343
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• 2024

Objective : To understand how Chungsangboha-tang (CSBHT) is being utilized in clinical practice and research in Korea, clinical studies related to CSBHT published in domestic academic journals were analyzed. Methods : The search was conducted using the following six databases: Korean Traditional Knowledge Portal, Oriental Medicine Advanced Searching Integrated System, ScienceON, Research Information Sharing Service, Koreanstudies Information Service System, and The Journal of Internal Korean Medicine. After selecting relevant literature published before June 24, 2024, the studies were classified and analyzed according to their research design. Results : The final selection comprised 20 studies categorized as follows: 1 non-randomized controlled trial and 10 before-and-after studies in prospective clinical research, along with 7 case reports and 2 retrospective chart reviews in retrospective clinical studies. Among the 233 participants included in these studies, 169 had asthma, 53 had chronic cough, and 5 had chronic obstructive pulmonary disease. Additionally, other conditions reported included Churg-Strauss syndrome, pulmonary Langerhans cell histiocytosis, non-tuberculous mycobacterial pulmonary disease, bronchiectasis, and pulmonary hypertension. CSBHT was administered as a decoction in 13 studies, as granules in 6 studies, and both in one study. The most frequently used assessment tools were pulmonary function tests and quality of life evaluations. For safety assessment, liver function test results and adverse events were reported. Conclusion : To enhance the utilization of CSBHT in Korean medicine clinical practice, continuous accumulation of domestic clinical research is essential. Moreover, meticulously designed randomized controlled trials are necessary to elevate the level of evidence.

• Journal of TMJ Balancing Medicine
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• v.8 no.1
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• pp.1-5
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• 2018

Objectives: The purpose of this review is to analyse the trends of clinical studies using oral appliance in Korean Medicine. Methods: We reviewed Korean Medicine papers by searching Korean web databases 'Korea Traditional Knowledge Portal (KTKP)', 'Korea Medical Information Portal (OASIS)', 'Academic Research Information Service (RISS)', 'Scientific and Technological Information Integration Service (NDSL)'. We classified the papers by the year of publishment, the title of journals, the type of study and contents. Results: 1. Clinical studies using oral appliance have been increasingly published since 2011. 2. Most of the studies were published in the Journal of TMJ Balancing Medicine. 3. 33 research papers were divided in to 6 original articles, 27 case reports. But almost presented a low level of evidence. 4. In the content of the studies, oral appliance were used for various diseases such as nervous system, musculoskeletal system and visceral system. Conclusions: We expect that various studies and clinical application will be actively carried out with the development of technology related to oral appliance.

• Journal of Korean Medicine for Obesity Research
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• v.18 no.2
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• pp.128-143
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• 2018

Objectives: The purpose of this study is to investigate the efficacy and the mechanisms of dietary supplements in cellulite treatment, and then to provide the theoretical and clinical basis for the cellulite treatment in Korean Medicine. Methods: We searched for articles from Korea, China, and English electronic database (Koreanstudies Information Service System [KISS], National Digital Science Library [NDSL], KMbase, Research Information Sharing Service [RISS], Oriental Medicine Advanced Searching Integrated System [OASIS], National Assembly Library, Korean Traditional Knowledge Portal, Google scholar, PubMed, Scopus, China National Knowledge Infrastructure [CNKI]) until April 2018. We chose clinical trial studies by inclusion criteria through titles, abstracts and articles. Results: A total of 10 studies were selected through search. The experimental group had shown more effective cellulite improvement in 90% of studies. Also, improvement of symptoms related with cellulite like pain, edema, heaviness and increase of skin surface temperature were observed in experimental group. In addition, the density of connective tissues of the dermal layer was increased in experimental group. Conclusions: The use of dietary supplements in cellulite treatment is thought to be effective through mechanisms that antioxidant efficacy, microcirculation improvement, interstitial matrix improvement, diuretic effect, and skin metabolic activity effect.

• Korean Journal of Acupuncture
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• v.40 no.4
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• pp.149-155
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• 2023

Objectives : Hapgok (LI4) is one of the most widely used acupoints in clinical practice. This study aims to investigate the trend of clinical studies including LI4 acupoint stimulation in Korea. Methods : Papers of clinical researches including LI4 acupoint stimulation in Korean journals were searched in Korean databases of Korean Traditional Knowledge Portal, Korean Studies Information Service System, Korea Citation Index, DBpia, Research Information Sharing Service, and ScienceON. The papers were then analyzed focusing on the number of publications by year, the types of the clinical research, interventions, research topics, institutes, and journals. Results : A total of 154 publications were included in this study. The first paper was published in 1981, and the number of papers has gradually increased since the 1990s. Although LI4 acupoint stimulation was included, most of the papers had additional acupoints and interventions. Diseases of the nervous system were the most common, followed by diseases of the digestive system and diseases of the circulatory system. Kyung Hee University is the institution that published the most papers, and the journal that published the most papers is The Journal of Korean Oriental Internal Medicine. Conclusions : Since the 1990s, the number of clinical studies on LI4 acupoint has increased. However, the results of the studies are insufficient to prove the efficacy of LI4 acupoint because most of the studies were case reports using additional acupoints and interventions. Therefore, more rigorous studies are needed to prove the efficacy of LI4 acupoint.

• Journal of Korean Medicine for Obesity Research
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• v.22 no.2
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• pp.147-157
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• 2022

Objectives: The purpose of this study is to research domestic and foreign trend of pharmacopuncture treatment on obesity during recent 10 years. Methods: 5 Databases (Korean Studies Information Service System, Research Information Sharing Service, Oriental Medicine Advanced Searching Integrated System, Scopus, PubMed) were searched with keywords of ('pharmacopuncture', 'herbal acupuncture', 'aquapuncture', 'obesity') from 2012 to 2022. Results: 25 Articles were selected and analyzed. 15 articles (60%) were animal experimentations, 8 articles (32%) were case reports, 1 article (4%) was cell experimentation, and 1 article (4%) was clinical trial. In this study, 25 articles were analyzed by subject, acupoints, injections, metrics and results. Pharmacopuncture treatment for obesity is continuously being studied, and the anti-inflammatory effect as well as the effect of reducing obesity factors has been revealed. Conclusions: This study suggests the efficacy and future development of pharmacopuncture for obesity. The studies of the past decade have been concentrated on animal experiments, so many clinical trials and various studies on new complex pharmacopuncture for obesity are expected.

• The Journal of Korean Obstetrics and Gynecology
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• v.33 no.4
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• pp.23-35
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• 2020

Objectives: The purpose of this study is to confirm the effectiveness and safety of acupuncture for Endometriosis. So providing a clinical basis for abdominal acupuncture treatment helping to develop clinical practice guideline. Methods: Clinical studies applying acupuncture on Endometriosis were searched through Pubmed, China Academic journal (CAJ), Koreanstudies Information Service System (KISS), Research Information Sharing Service (RISS), Oriental Medicine Advanced Searching Integrated System (OASIS). Interventions and results of the selected clinical studies were analyzed. Results: 8 Clinical studies were finally included according to inclusion and exclusion criteria. Those were randomized controlled studies. All of those studies were searched in China Academic journal (CAJ) in Chinese. Interventions of control group were made with simple acupuncture and oral administration of Danazol or herbal medicine. Outcome measurements included Treat effect, Relief in related symptoms, and CA-125. All studies reported statistically significant results on abdominal acupuncture and there were no serious adverse effects. Conclusions: This study suggested abdominal acupuncture has statistically significant treat effect. Thus this treat helps improve quality of life for patients. However the results should be taken cautiously as more clinical studies are needed.

• The Journal of Korean Medicine
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• v.45 no.1
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• pp.80-99
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• 2024

Objectives: The objective of this study was to review clinical studies conducted over the last ten years that investigated weight or fat loss interventions that can preserve muscle or fat-free mass in Sarcopenic obesity Methods: PubMed, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), Research Information Sharing Service (RISS) and Korea Studies Information Service (KISS) were searched for Randomized clinical trials that had investigated all-type of interventions on the management of sarcopenic obesity from October 2013 to September 2023. Results: A total of 14 studies met all the inclusion criteria. Interventions that increase muscle mass while reducing body fat at the same time included resistance training (including using elastic bands) and whole-body electromyostimulation(WB-EMS) in exercise intervention and Hypocaloric high-protein diet in nutritional intervention, exercise and nutritional combined intervention, and combination intervention of electrical acupuncture and amino acid supplementation. Among them, the most positive method of changing the body composition in sarcopenic obesity was the electric acupuncture and amino acid supplements. Conclusion: Varying diagnostic criteria and management interventions for sarcopenic obesity in the included studies made it hard to maintain homogeneity across the studies. Well-defined criteria for diagnostic sarcopenic obesity should be considered. In addition, since all of the interventions examined did not show sufficient clinical effectiveness, follow-up studies are needed to confirm effective interventions for sarcopenic obesity patients in the future.

• Journal of Society of Preventive Korean Medicine
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• v.22 no.2
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• pp.55-63
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• 2018

Objectives : This study was conducted to survey on the research trends of Pharmacopuncture in Korea. Methods : We searched Korean research database by using keyword 'Pharmacopuncture', 'Bee venom'. Korean research databases were Korean Studies Information Service System(KISS), Research Information Service System(RISS), National Digital Science Library(NDSL) and Korean Medicine Information System(OASIS). We classified articles identified by publish year, type of research and diseases. Results : We analyzed 533 studies. Clinical studies and non-clinical studies except literature studies were decreased from 2015. However, Literature studies had not shown particular change over the past decade. Pharmacopuncture treated disease was classified by Korean standard classification of disease(KCD), M-code (37.8%), G-code(18.4%) were frequently used. Conclusions : A variety of disease was treated by pharmacopuncture. It is necessary to increase the level of evidence of pharmacopuncture. through additional studies in the future.

• Journal of Korean Medicine Rehabilitation
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• v.31 no.4
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• pp.75-86
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• 2021

Objectives This study aimed to analyze the research trends in clinical studies on the traditional Korean medicine used for cancer treatment between 2011 and 2020. Methods We searched 7 Korean web databases (Research Information Sharing Service [RISS], Oriental Medicine Advanced Searching Integrated System [OASIS], Koreanstudies Information Service System [KISS], Korean Medical database [KMBASE], DBpia, Korea Institute of Science and Technology Information [KISTI], and KoreaMed) and classified collected papers dated between 2011 and 2020 by the year of publication, publication journal, study design, type of cancer affecting the patients, interventions used, evaluation system used, and combination with conventional medicine. Results A total of 167 papers were collected. More than 10 papers were published annually. The papers were mainly published in the Journal of Korean Traditional Oncology (28.7%). The predominant type of the study was case study (67.7%). The main type of cancer was breast cancer, affecting 262 patients. Most of the studies reported using multiple traditional Korean medicine treatments (55.1%). Eighty-nine studies reported using clinical laboratory tests for evaluation. Most of the patients took conventional medicine simultaneously (608 patients). Conclusions Research related to Korean medicine for cancer patients is at a rudimentary level. Therefore, for further clarity, high evidence-based researches, including randomized controlled trials and cohort studies, should be conducted.

• The Journal of Korean Medicine
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• v.38 no.3
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• pp.73-85
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• 2017

Objectives: The purpose of this study was to investigate the status of Korean medicine treatment, and to analyze problems and demands to provide basic data on Korean medicine in military medical services. Methods: This survey was completed by 30 volunteer Korean medicine military doctors on service via a web-based questionnaire system. The questionnaire was developed through in-depth interviews with Korean medicine military doctors and consisted of general information on the subject, overall characteristics of the medical environment, current status of Korean medicine care in each workplace, problems and needs, and related clinical evidence and education. Results: Korean medicine military doctors administered acupuncture treatment most frequently in clinical practice. The most common complaints were related to musculoskeletal diseases, which accounted for 86.5% of all diseases, including those of the respiratory, digestive, and nervous systems. Most of the problems in Korean medicine care were pointed out as being due to a lack of awareness of Korean medicine in the military. Many doctors were aware that it is necessary to establish clinical evidence for Korean medicine in the military, and were also positive about the possibility of performing clinical research in the military, but the experience of actual participation in clinical research or related education was uncommon. Conclusions: Korean medicine military treatment differs from private medical care due to the specificity of each workplace and the military medical system. In the future, it will be necessary to establish an appropriate Korean medicine treatment model in the military suitable for these characteristics and strategic plans for clinical evidence.