• 제목/요약/키워드: Clinical Effectiveness

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위축성 질염의 좌훈 치료 연구에 관한 체계적 문헌 고찰 (Systematic Review of Fumigation Therapy for Atrophic Vaginitis)

  • 백선은;장새별;최경희;유정은
    • 대한한방부인과학회지
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    • 제29권1호
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    • pp.92-101
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    • 2016
  • Objectives: The purpose of this systematic review was to overview and evaluate the effectiveness of fumigation treatment for women with atrophic vaginitis. Methods: We searched articles from Pubmed, Chinese Academic Journals (CAJ) and Oasis online databases. Searching keywords were ‘fumigation’, ‘atrophic vaginitis’, ‘vaginitis’, ‘阴道炎’, ‘膣炎’, ‘老年性 阴道炎’, ‘坐熏’, ‘熏洗’, ‘熏浴’, ‘좌훈요법’, ‘질염’, ‘위축성질염’. After searching the articles, we performed quality assessment using Cochrane risk of bias (RoB) tool. Results: Among the 142 articles were searched, 5 randomized controlled clinical trials (RCTs) were finally selected. All of 5 studies showed that fumigation treatment has significant effect on atrophic vaginitis in terms of the effectiveness rate, but 3 studies were not statistically significant. Conclusions: Our systematic review found encouraging but limited evidence of fumigation therapy for atrophic vaginitis. We recommend clinical trials which obtain stronger evidence without the demerits of trial design.

운동 프로그램이 요추유합술 환자의 통증과 일상생활활동장애에 미치는 효과 (Effectiveness of a Post-operative Exercise Program on Pain and Disability Activities in Patients with Lumbar Spinal Fusion)

  • 이미영;김복자
    • 임상간호연구
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    • 제17권3호
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    • pp.388-398
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    • 2011
  • Purpose: This study was to develop a post-operative exercise program, apply it to patients undergone lumbar spinal fusion surgery, and evaluate the effectiveness of the program on pain and disability activities of daily living. Methods: Fifty six patients who had lumbar spinal fusion were enrolled in this study. The patients were divided into two groups; 28 patients in the intervention group completed post-operative lumbar exercise program including walking for four weeks and 28 patients in the control group only did walking exercises. The degrees of pain on low back and leg were evaluated using visual analog scale (VAS) and the functional outcome was evaluated using the Korean version of Oswestry Disability Index (KODI) before surgery and 5 weeks after surgery. The data were analyzed using descriptive statistics, Chi-square test, t-test with SPSS 18.0 program. Results: Low back and leg pain of the participants in both experimental and control groups were improved after surgery compared to pre-surgery pain. However, there was no statistically significant difference between the groups. KODI score in the intervention group was significantly lower than that of the control group (p=.014). Conclusion: The developed post-operative exercise program in patients with lumbar spinal fusion surgery seems to be a useful intervention to reduce disability in activities of daily living.

한포진 치료의 중의학 임상연구 동향 - 무작위 대조군 임상연구를 중심으로 - (An Overview of Clinical Studies for Pompholyx in Traditional Chinese Medicine - Literature Review based on Randomized Controlled Trials -)

  • 우정아;박범찬;최일신;김기봉;천진홍
    • 대한한방소아과학회지
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    • 제35권4호
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    • pp.82-95
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    • 2021
  • Objectives The purpose of this study is to analyze clinical studies on the effectiveness of TCM (traditional Chinese medicine) for pompholyx treatment and provide evidence for Korean medicine use. Methods Randomized controlled trials (RCT) which used TCM as a treatment for pompholyx were searched in China National Infrastructure (CNKI) platform. The risk of bias of studies was assessed by using Cochrane risk of bias (RoB) 2.0 tool. Results The selected 10 RCTs showed that the experimental group treated with either TCM alone or with a combination of TCM and Western medicine showed more significant therapeutic effect compared to the control group which Western medicine alone. Conclusions Based on the studies from China, TCM may be an effective treatment for pompholyx. This provides evidence for Korean medicine use, and its possible effectiveness in treating pompholyx

Oseltamivir를 투약한 양성대조군과 비교한 인플루엔자의 한약 치료 효과 - RCT 연구를 중심으로 - (Review of Clinical Research for Herbal Medicine in the Treatment of Influenza Compared with Oseltamivir)

  • 장은하;민상연;김장현
    • 대한한방소아과학회지
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    • 제33권3호
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    • pp.1-14
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    • 2019
  • Objectives The purpose of this study is to analyze clinical studies on effectiveness of herbal medicine in influenza compared with Oseltamivir. Methods We searched the randomized controlled trials (RCTs) with herbal medicine treatment on influenza compared to Oseltamivir from the Pubmed, CNKI, OASIS, NDSL, J-stage, and CiNii. Results 14 out of 717 studies were selected and analyzed. The herbal medicine treatment had a significant effects on the alleviation of fever, cough, sore throat than the Oseltamivir control treatment. Herbal medicine had same therapeutic effectiveness like Oseltamivir on duration of influenza-like symptoms and viral shedding. No serious adverse reactions were reported from the herbal medicine treatment. Conclusions The results of these trials showed that the herbal medicine may be more effective than the Oseltamivir in the treatment of influenza. Well-designed RCTs for domestic herbal medicine treatment on influenza are needed to prove its efficacy clearly.

척추측만증의 추나치료에 대한 문헌 고찰 연구 보고 (Chuna Manual Therapy for Spinal Scoliosis : A Review of Clinical Study)

  • 허인
    • 척추신경추나의학회지
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    • 제14권1호
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    • pp.39-47
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    • 2019
  • Objectives : The purpose of this study was to evaluate the scientific literature demonstrating the effectiveness of Chuna manual therapy (CMT) in the treatment of spinal scoliosis. Methods : A literature search was conducted using eight electronic databases to identify all randomized controlled clinical trials (RCTs) that investigated CMT as a treatment for spinal scoliosis. The Cochrane risk of bias tool was used to assess the methodological quality of each RCT. Results : Five RCTs met our inclusion criteria and were included in the analysis. These studies demonstrated positive results of CMT with respect to the reduction of Cobb's angle, vertebral rotation angle score, bending test score, and efficacy rate compared with brace treatment. Positive results were also assured, in terms of the reduction of Cobb's angle, pulmonary function, and efficacy rate when comparing CMT combined with other therapy with brace treatment, gymnastic training, or traction therapy. Conclusions : This review has identified encouraging and limited evidence of CMT for the treatment of spinal scoliosis. However, to obtain stronger evidence, without the disadvantages of study design and quality, we recommend that treatment effectiveness of CMT for spinal scoliosis is investigated further using a well-designed RCT.

인유두종바이러스 관련 질환의 예방을 위한 남성 대상 백신의 임상적 유용성 (Clinical Benefit of Vaccinating Male Against HPV-related Disease)

  • 이세영
    • 대한두경부종양학회지
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    • 제38권1호
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    • pp.11-16
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    • 2022
  • HHPV (Human Papillomavirus) is a DNA virus that can cause benign lesions, genitourinary cancer, and oropharyngeal cancer by penetrating the mucous membrane and skin. It is widely known to be transmitted mainly through sexual contact. As with many viral infections, vaccines have been developed to prevent infection with HPV. Currently, in many countries, HPV vaccines are mainly used for national immunization for women to prevent diseases that traditionally occur frequently in women, especially cervical cancer. However, since the vaccination rate is relatively low, many countries are struggling with ways to increase the vaccination rate. Meanwhile, the incidence of oropharyngeal cancer caused by HPV in men has been increasing recently. In the United States, the annual number of oropharyngeal cancers in men already exceeds the number of cervical cancers in women, so HPV infection in men has emerged as a major problem. Accordingly, interest in HPV vaccination in men has also increased, and studies on the effectiveness and necessity of vaccination of both women and men compared to women alone are being actively conducted. In this paper, the evidence of HPV vaccination for men will be reviewed through previous studies, and its validity and cost-effectiveness will be analyzed to bolster the clinical usefulness of HPV vaccination for men.

간호진단 전산시스템 개발을 위한 연구 (A Study on the Development of a Computerized Nursing Diagnoses System)

  • 최영희;이향련;김혜숙;박현경
    • 대한간호학회지
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    • 제28권2호
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    • pp.468-478
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    • 1998
  • The purpose of this study was to develop the computerized nursing diagnoses system for clinical application and activation of nursing diagnoses based on validity verification. In addition, our research team also performed system tests in clinical situations, to identify ways to improve the program and make it more practical. Nursing Diagnoses System will increase nurses' knowledge and experience of the application of nursing diagnoses in clinical situations and development of nursing interventions by nurses as well as the effectiveness of hospital computerized systems. We expect this system can contribute to an improvement in the quality of nursing care. Also we will continuously evaluate and revise the system related to the utilization of the program.

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외과영역에서의 감염증에 대한 Vistamycin 의 사용경험 (Clinical Studies on Ribostamycin sulfate)

  • 강정호
    • Journal of Chest Surgery
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    • 제11권3호
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    • pp.368-372
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    • 1978
  • Ribostamycin sulfate is a new aminoglycoside antibiotic which is effective against organisms resistant to other conventional antibiotics, Particularly E. coli, and Staphylococcus group. Our clinical studies were performed on 20 patients who were admitted to Thoracic Surgical Dept of National Medical Center from May '77 to September '77, and the following results were obtained; 1. Among 20 patients, 13 were excellently improved and 4 responded moderataly, but 3 patients were not improved. So, 85% of the patients were controlled with Ribostamycin sulfate administration. 2. The rate of effectiveness of Ribostamycin sulfate was 85.7% against E. coli, 92.3% against Staphylococcus, and 75% against klebsiella, revealing 83.3% in average. 3. No side effects were observed. 4. From our clinical studies, Ribostamycin sulfate is expected to possess in high therapeutic value in surgical infectins caused by both gram positive and negative microorganisms.

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이비인후과 염증질환에 대한 데옥시리보뉴클레아제-브로멜라인정의 효과 조사 (The Effect of Deoxyribonuclease-Bromelain Tablet in Patients with Inflammation of Otorhinolaryngology)

  • 박성용
    • 한국임상약학회지
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    • 제14권2호
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    • pp.71-77
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    • 2004
  • The author has tested the clinical efficacy and safety of an anti-inflammatory drug in patients with inflammation of the otnrhinolaryngology. Deoxyribonuclease prepared from bovine pancreas destroyed fibers and reduced the viscosity of the exudates. Bromelain is a group of proteolytic enzymes which are known to have an effect on inflammation, swelling, and pain in inflammatory disorders. The mucolytic and anti-inflammatory properties of deoxyribonuclease associated with bromelain in inflammation of otorhinolaryngology were assessed in 67 patients. A standard dose of 3 tablets of deoxyribonuclease bromelain tablet was given for not less than 7 days. In all tile groups of patients considered, the drug showed a considerable therapeutic effectiveness. At the end of 7-28 days treatment, more than $89.6\%$ of treatment was improved. These findings suggest that it could be permitted to use deoxyribonuclease-bromelain tablet in patients with inflammation of the otorhinolaryngology.

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대편난(大便難)을 주소로 하는 소아 환자 5례에 대한 정장요법의 치료 효과에 대한 임상적 고찰 (A Clinical Study on the Effects of Jungjangyobup on 5 Constipation Children)

  • 석연희;민상연;김장현
    • 대한한방소아과학회지
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    • 제25권3호
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    • pp.27-34
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    • 2011
  • Objectives: The purpose of this study is to report the clinical effects of Jungjangyobup on children's constipation. Methods: We treated the 5 case with Jungjangyobup, one of retention enema therapies with Gwakhyangjunggisan. We observed its effects since March 2010 up to November 2011. Results 4 cases out of 5 cases improved constipation and other constipation-related symptomssuch as vomiting, and abdominal pain. Conclusions: This study has shown that oriental medical treatment on children's constipation was effective. The more clinical cases like this case might be needed to confirm this effectiveness of Jungjangyobup.