• The Journal of the Korea institute of electronic communication sciences
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• v.19 no.1
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• pp.283-288
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• 2024

In this paper, a novel mechanism for overcoming obstacles is studied by designing an All-Directional RC car for obstacle traversal and creating test courses with various obstacles. We propose an algorithm for controlling the RDS3115 servo motor and utilize a gyro sensor to detect the incline of various obstacle terrains, adjusting the servo motor's angle to enable the RC car to navigate the terrain. Through terrain experiments in the test course, we determined the most suitable RC car turning angles for traversing all obstacle terrains created in the experimental terrain.

• Biomolecules & Therapeutics
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• v.21 no.4
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• pp.307-312
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• 2013

Quetiapine is an atypical or second-generation antipsychotic agent and has been a subject of a series of case report and suggested to have the potential for misuse or abuse. However, it is not a controlled substance and is not generally considered addictive. In this study, we examined quetiapine's dependence potential and abuse liability through animal behavioral tests using rodents to study the mechanism of quetiapine. Molecular biology techniques were also used to find out the action mechanisms of the drug. In the animal behavioral tests, quetiapine did not show any positive effect on the experimental animals in the climbing, jumping, and conditioned place preference tests. However, in the head twitch and self-administration tests, the experimental animals showed significant positive responses. In addition, the action mechanism of quetiapine was found being related to dopamine and serotonin release. These results demonstrate that quetiapine affects the neurological systems related to abuse liability and has the potential to lead psychological dependence, as well.

• Proceedings of the Korean Society for Agricultural Machinery Conference
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• 1993.10a
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• pp.1186-1195
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• 1993

The Japanese type combine harvester has adopted rubber crawlers for the driving mechanism from first production . However, combine harvesters with movable track rollers in the rubber crawler system have been adopted recently for the purpose of stability at the time of climbing over the footpaths between rice fields, as the results of the machines becoming large. However, the dynamic characteristics of movable track rollers have not been clarified. For this reason, the design of movable track rollers depends on trial and errors. It is known that vibration characteristics of the vehicle with movable track rollers are different from the vibration characteristics of the vehicles with fixed track rollers even though the track roller arrangements are the same. Therefore, the theoretical analyses of movable track rollers must be hurried in order to formulate a reasonable track roller arrangement design. the authors have studied the vibration characteristics of the rubber crawler ve icle with fixed track rollers. in this study, the dynamic model of the vehicle with movable track roller sis compared with the dynamic model of the vehicle with fixed track rollers. Next, motions are simulated to analyze the movable track rollers by expanding the motion equation which were constructed for the dynamic model of the fixed track rollers.

• Journal of Oriental Neuropsychiatry
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• v.19 no.2
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• pp.151-163
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• 2008

Objective : Recent studies indicate that the deposition of beta-amyloid ($A{\beta}$) is related in the pathogenesis of Alzheimer's disease (AD), but the underlying mechanism is still not clear. Method : To investigate the potential cellular functions of APP and LMK02, we use transgenic drosophila as a model was treated with either LMK02, and the effect in APP expression was determined by climbing assay. LMK02 have been shown to be neuroprotective in fly model systems. We asked whether dietary supplementation with LMK02 would influence behavior and AD-like pathology in a transgenic fly model. Result LMK02 water extract have attenuated fly death in vivo. LMK02-treated fly increased percentage of flight ability more longly and survival ratio more than controls. APP-GRIM drosophila treated with LMK02 had significantly less accumulation of APP deposition in the eye and brain as compared to control drosophila. Conclusion : These results suggest that LMK02 prevent APP-induced neurotoxicity through attenuating flies death induced by APP, and may be useful as potential therapeutic agents for AD.