• Journal of KIISE:Software and Applications
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• 제29권1_2호
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• pp.91-97
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• 2002

This paper describes a heuristic search technique carrying out collision avoidance for Autonomous Underwater Vehicles(AUVs). Fuzzy relational products are used as the mathematical implement for the analysis and synthesis of relations between obstacles that are met in the navigation environment and available candidate nodes. In this paper, we propose a more effective evaluation function that reflects the heuristic information of domain experts on obstacle clearance, and an advanced heuristic search method performing collision avoidance for AUVs. The search technique adopts fuzzy relational products to conduct path-planning of intelligent navigation system. In order to verify the performance of proposed heuristic search, it is compared with $A^*$ search method through simulation in view of the CPU time, the optimization of path and the amount of memory usage.

• Journal of Veterinary Science
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• 제21권3호
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• pp.35.1-35.11
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• 2020

Background: Despite common use of tylosin in turkeys, the pharmacokinetic (PK) data for this drug in turkeys is limited. Within a few months of growth, PK of drugs in turkeys undergoes changes that may decrease their efficacy due to variable internal exposure. Objectives: The objective of this study was to investigate the influence of age on the PK of a single intravenous (i.v.) and oral administration of tylosin to turkeys at a dose of 10 and 50 mg/kg, respectively. Methods: Plasma drug concentrations were measured using high-performance liquid chromatography with UV detection. The PK parameters were assessed by means of non-compartmental approach and were subjected to allometric analysis. Results: During a 2.5-month-long period of growth from 1.4 to 14.7 kg, the median value for area under the concentration-time curve after i.v. administration increased from 2.61 to 7.15 mg × h/L and the body clearance decreased from a median of 3.81 to 1.42 L/h/kg. Over the same time, the median elimination half-life increased from 1.03 to 2.96 h. For the oral administration a similar trend was noted but the differences were less pronounced. Bioavailability was variable (5.76%-21.59%) and age-independent. For both routes, the plasma concentration of the major tylosin metabolite, tylosin D, was minimal. Protein binding was age-independent and did not exceed 50%. Allometric analysis indicated a relatively poor predictivity of clearance, volume of distribution and elimination half-life for tylosin in turkeys. Conclusions: Age has a significant impact on tylosin PK in turkeys and dosage adjustment may be needed, particularly in young individuals.

• The Transactions of The Korean Institute of Electrical Engineers
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• 제57권11호
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• pp.1922-1928
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• 2008

The thermal rating of a conductor are maximum continuous current capacity and short time emergency current capacity. The overload operation for a faults have an effect on a conductor lifetime. Its time duration and overload level are limited to facility conditions of transmission lines. The short time emergency current capacity in KOREA observe the KEPCO's DESIGN RULE 1210, but its rules are not included to concept of an allowable short time duration. This papers are described to the calculation concept of short time emergency current capacity considering a time duration and an overload level. And we suggested a operation grouping and its maximum conductor temperature considering facility conditions - conductor lifetime, stability of connection points, conductor height above ground and clearance, in the operating and new T/L.

• The Korean Journal of Nuclear Medicine
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• 제32권3호
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• pp.266-275
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• 1998

Purpose: We measured pulmonary epithelial permeability by $^{99m}Tc-DTPA$ radioaerosol clearance in patients with diabetes and correlated with the presence of microangiopathy to understand the pathophysiology of pulmonary microangiopathy and evaluate $^{99m}Tc-DTPA$ radioaerosol clearance as a diagnostic test to assess pulmonary microangiopathy. Materials and Methods: We performed $^{99m}Tc-DTPA$ radioaerosol scan in 10 normal subjects, 10 asymptomatic smokers, 20 diabetic patients without history of smoking (10 with microangiopathy, 10 without microangiopathy). $^{99m}Tc-DTPA$ clearance half-time ($T_{1/2}$) was calculated, then compared with the result of chest radiography and pulmonary function test. Results: Chest radiography and pulmonary function test were normal in all subjects. There were no significant difference of clinical or laboratory characteristics between these groups except age. The diabetic patients with microangiopathy were significantly older (p<0.05). The $T_{1/2}$ of normal subjects and asymptomatic smokers were significantly different ($65.2{\pm}23.7min$ vs $39.6{\pm}9.8min$, p<0.05). For diabetic patients with microangiopathy, the $T_{1/2}$ was $90.5{\pm}46.5min$ and significantly delayed when compared with those of normals and asymptomatic smokers (p<0.05). However, the $T_{1/2}$ of diabetic patients without microangiopathy, $70.0{\pm}12.7min$, was not significantly different from those of normals or asymptomatic smokers (p>0.05). No significant correlation was found between the $T_{1/2}$ and spirometric parameters including DLco, FVC, $FEV_1,\;FEV_1/FVC$ (%) and $FEF_{25-75%}$ in all subjects, and between the $T_{1/2}$ and duration of diabetes ;in diabetic patients. Conclusion: Eventhough the influence of age can't be excluded, delayed $^{99m}Tc-DTPA$ clearance half-time ($T_{1/2}$) in diabetic patients with microangiopathy indicates decreased pulmonary capillary permeability as one of the pathophysiologic results of pulmonary microangiopaththy. Further studies are needed in larger number of age matched control and diabetic patients to evaluate the diagnostic efficacy.

• Nuclear Engineering and Technology
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• 제53권6호
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• pp.1979-1990
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• 2021

Evacuation Time Estimate (ETE) can provide decision-makers with a likelihood to implement evacuation of a population with radiation exposure risk by a nuclear power plant. Thus, the ETE is essential for developing an emergency response preparedness. However, studies on ETE have not been conducted adequately in Korea to date. In this study, different cohorts were selected based on assumptions. Existing local data were collected to construct a multi-model network by TSIS-CORSIM code. Furthermore, several links were aggregated to make simple calculations, and post-processing was conducted for dealing with the stochastic property of TSIS-CORSIM. The average speed of each cohort was calculated by the link aggregation and post-processing, and the evacuation time was estimated. As a result, the average cohort-based evacuation time was estimated as 2.4-6.8 h, and the average clearance time from ten simulations in 26 km was calculated as 27.3 h. Through this study, uncertainty factors to ETE results, such as classifying cohorts, degree of model complexity, traffic volume outside of the network, were identified. Various studies related to these factors will be needed to improve ETE's methodology and obtain the reliability of ETE results.

• Korean Journal of Clinical Pharmacy
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• 제11권2호
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• pp.57-61
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• 2001

The effect of circadian rhythm on the pharmacokinetics of acebutolol was studied in rabbits administered intravenous 5 mg/kg dose of acebutolol at 09:00 in the morning (a.m) and 22:00 in the evening (p.m). A significant effect of circadian rhythm of pbarmacokinetic parameters as a function of time of day was noted in rabbits, showing lower total body clearance (CLt), higher plasma concentration and the area under the plasma concentration time curve (AUC) when acebutolol was given in the evening. The plasma concentration of acebutolol was increased significantly (p<0.05) at 12-24 hr after dosing in the evening. The AUC was greater in the evening $(111\%)$ than that in the morning and $CL_t$, was higher when acebutolol was given in the morning ($1.12\pm0.24$ ml/hr) versus in the evening ($1.01\pm0.22$ ml/hr), but those were not significant. Therefore, It is reasonable to consider individual circadian rhythm for effective dosage regimen of acebutolol in clinical chronotherapeutics.

• Proceedings of the KSME Conference
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• 대한기계학회 2004년도 추계학술대회
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• pp.302-307
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• 2004

The major flow-induced vibration mechanisms such as fluid-elastic and turbulence excitation can cause the various types of wear of the steam generator tubes in unclear power plant. It is generally accepted that the tube wear due to vibration is affected by the presence of gap clearance between tube and support plate. Connors showed that the tube wear depth could be estimated by using the relationship between wear volume and sliding distance for contact time. Au-Yang predicted the wear depth by using the nonlinear characteristics of normal work rate to contact time. In this study the effect of gap size on the steam generator tubes wear is analyzed by deriving the wear depth versus normal work rate relationship from these previous results.

• Proceedings of the KIEE Conference
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• 대한전기학회 2011년도 제42회 하계학술대회
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• pp.706-707
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• 2011

The insertion of the crowbar system in the doubly fed induction generator rotor circuit for a short period of time during grid disturbance enables a more efficient way of limiting transient rotor current and hence protecting the rotor side converter (RSC) and the DC - link capacitor. When crowbar is activated at fault occurrence and clearance time, RSC is blocked while DC -link capacitor and the grid side converter (GSC) can be controlled to provide reactive power support at the PCC and improve the voltage which helps to comply with grid codes. In this paper, control strategies for crowbar system to limit the rotor current during fault is presented with RSC and GSC controllers are modified to control PCC voltage during disturbance to enhance DFIG wind farm to comply with some strict grid codes. Model simulated on MATLAB/Simulink verify the study through simulation results presented.

• International Journal of Automotive Technology
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• 제7권5호
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• pp.619-624
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• 2006

This paper presents design of a vehicle stop-and-go cruise control strategy based on analyzed results of the manual driving data. Human drivers driving characteristics have been investigated using vehicle driving data obtained from 100 participants on low speed urban traffic ways. The control algorithm has been designed to incorporate the driving characteristics of the human drivers and to achieve natural vehicle behavior of the controlled vehicle that would feel comfortable to the human driver under low speed stop-and-go driving conditions. Vehicle following characteristics of the cruise controlled vehicle have been investigated using a validated vehicle simulator and real driving radar sensor data.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 한국정밀공학회 1996년도 춘계학술대회 논문집
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• pp.635-640
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• 1996

A thermo-elastic system in the production machine has highly nonlinear dynamic characteristics. In general, the finite element method is utilized for accurate analysis. However, it requires large computing time. Thus, thermo-elastic systems are usuallymodeled as electric and fluid system using lumped para,eter. In this paper. we propose the bondgraph model and transient simulation methodology of thermo-elastic system in consideration of various boundary and joint contact conditions. Consequently, the proposed method ensures a possibility of its on-line compensation about undesirable phenomena by using real time estimate process and electronic cooling device for thermal appropriate behavior. Thermo-elastic model consisting of bush and shaft including contact condition is presented.