• Biotechnology and Bioprocess Engineering:BBE
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• 제7권1호
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• pp.6-9
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• 2002

In this work we have investigated the feasibility of virus clearance by flocculation and tangential flow microfiltration. Chinese hamster ovary cell feed streams were spiked with minute virus of mice and then flocculated using cationic polyelectrolytes prior to tangential flow microfiltration. Our results indicate that flocculation prior to microfiltration leads to more than 100 fold clearance of minute virus of mice particles in the permeate. Today, validation of virus clearance is a major concern in the manufacture of biopharmaceutical products. Frequently new unit operations are added simply to validate virus clearance thus increasing the manufacturing cost. The results obtained here suggest that virus clearance can be obtained during tangential flow microfiltration. Since tangential flow microfiltration is frequently used for bioreactor harvesting this could be a low cost method to validate virus clearance.

• Journal of Advanced Marine Engineering and Technology
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• 제28권5호
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• pp.735-745
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• 2004

A linear cascade of NACA 65-1810 profiles are investigated for tip leakage flow characteristics. and calculation results are compared with experimental result. STAR-CD commercial code was used to solve the three dimensional incompressible Navier-Stokes equation that was adopted for steady flow and high Reynolds $\kappa$- $\varepsilon$turbulent model. Numerical calculation of a linear cascade is carried out to investigate effect of tip clearance on pitchwise variations of velocity Profiles. and static pressure distributions on the blade surface at spanwise positions. In case of evolution of tip vortex core location. tip vortex geometry and static pressure at the center of the tip vortex core compared with experimental results. Calculation results are agreed well with the experimental data, and validated. The static pressure losses by tip leakage flow at 2% tip clearance were more than those at 1% tip clearance.

• International Journal of Fluid Machinery and Systems
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• 제7권1호
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• pp.28-33
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• 2014

In order to research the relationship between the tip clearance and leakage flow of centrifugal compressor, a high speed centrifugal compressor was investigated by using CFD. A numerical study on the effect of four different rotor tip clearance sizes of centrifugal compressor, which were 0.5times, 1 times, 1.5times and 2.0times of the design tip clearance, was carried out. Efficiency and pressure ratio curves were obtained under different mass flow. The reasons of the clearance vortex and the factors of vortex size were analyzed. The result indicated that with the increase of tip clearance size, the performance of the compressor changed obviously, the performance parameters such as efficiency and pressure ratio tended to decrease obviously. While, the leakage flow does not always lead to leak vortex. The strength of the vortex increased with the tip clearance. The size of leak vortex was affected by the pressure difference between the suction side and the pressure side of blade tip.

• Nuclear Engineering and Technology
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• 제54권7호
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• pp.2540-2549
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• 2022

For a pressurized water reactor power plant, the reactor coolant pump (RCP) is a kernel component. And for a canned motor RCP, the rotor system's properties determines its safety. The liquid coolant inside the canned motor RCP fills clearance between the metal shields of rotor and stator, forming a lengthy clearance flow. The influence of inlet preswirl on rotordynamic coefficients of clearance flow in canned motor RCP and their effects on the rotordynamic characteristics of the pump are numerically and experimentally investigated in this work. A quasi-steady state computational fluid dynamics (CFD) method has been used to investigate the influence of inlet preswirl. A vertical experiment rig has also been established for this purpose. Rotordynamic coefficients on different inlet preswirl ratios (IR) are obtained through CFD and experiment. Results show that the cross-coupled stiffness of the clearance flow would change significantly with inlet preswirl, but other rotordynamic coefficients would not change significantly with inlet preswirl. For the case of clearance flow between the stator and rotor cans, influence of inlet preswirl is not so significant as the IR is not large enough.

• 대한기계학회논문집B
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• 제27권3호
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• pp.389-397
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• 2003

Effect of tip leakage flow on through flow and performance of a centrifugal compressor impeller was numerically studied using CFX-TASC flow. Seven different tip clearances were used to consider the influence of tip clearance on performance. Secondary flow and loss factor were evaluated to understand the loss mechanism inside the impeller due to tip leakage flow. The calculated results were circumferentially averaged along the passage and at the impeller exit for quantitative discussion. Tip clearance effect on Performance could be decomposed into inviscid and viscous components using one dimensional equation. The inviscid component is related with the specific work reduction and the viscous component is related with the additional entropy generation. Two components affected Performance equally. while efficiency drop was mainly influenced by viscous loss. Performance and efficiency drop due to tip clearance were proportional to the ratio of tip clearance to exit blade height. A simple model suggested in the present study predict performance and efficiency drop quite successfully.

• Journal of Advanced Marine Engineering and Technology
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• 제26권3호
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• pp.353-361
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• 2002

The tip leakage flow passing through the clearance between rotor blade tip and casing shroud has been known to occupy an important portion of the rotor overall loss. In this study, flow characteristics in axial flow rotors with different tip clearances is investigated by experimental and numerical methods. The experimental study was carried out to measure static pressure and velocity profiles at the real rotating test rig. The axial flow rotors used for the experiments have ten blades and three different rotor diameter. The tip clearance heights are 1mm, 3mm, and 4.5mm. Measurements were done using spherical type five-hole probe by non-nulling method. The numerical study was carried out to calculate pressure distributions and velocity vectors at the same condition as the experiments in the flow fields of axial flow rotors using Phoenics code.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2008년도 춘계학술대회논문집
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• pp.240-243
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• 2008

In this paper, the design of Centrifugal Compressor which is used in sizes 50 horse power has 8 pressure ratio and numerical analysis of the flow within compressor varying tip clearance length are performed. To get high pressure ratio with low power the exit height of impellers is low but compressor has very high speed of revolution. So compressor has high specific speed although mass flow rate is very small. The shape of impellers at the first stage is carried out. Flow and performance characteristics of impellers has been analyzed by using a commercial CFD program, $Fine^{TM}$/turbo. The result shows that loss coefficient is affected by tip clearance length and compressor has proper tip clearance length. It is possible to decrease loss by selecting apt tip clearance length.

• 한국유체기계학회 논문집
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• 제2권1호
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• pp.73-80
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• 1999

Leakage vortices formed new blade tip causes an increase of total pressure loss near the casing endwall region and as a result, the efficiency of rotor decreases. The reduction of rotor efficiency is related to the size of the tip clearance. In this study, the three-dimensional flowfields in an axial flow rotor were calculated by varying the tip clearance under various flow rates, and the numerical results were compared with experimental ones. The effects of tip clearance and attack angle on the leakage vortex and overall performance, and the loss distributions were investigated through numerical calculations. In this study, tip leakage flow rate and total pressure loss by tip clearance were evaluated using numerical results and approximate equations were presented to evaluate the reduction of rotor efficiency by tip leakage flow.

• 한국전산유체공학회지
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• 제18권1호
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• pp.7-12
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• 2013

This paper presents a numerical investigation of the influences of various non-uniform tip clearances on the performance and flow field in a centrifugal compressor. Numerical simulations were conducted for three centrifugal compressor impellers in which the tip clearance height varied linearly from the leading edge to the trailing edge. The numerical result was compared with the experimental data for validation. Although the performance improved for low tip clearances, a smaller tip clearance at the trailing edge reduced the overall tip leakage flow more effectively than a smaller tip clearance at the leading edge. Therefore, a smaller tip clearance at the trailing edge lowered the mixing loss caused by interactions between the tip leakage flow and the main passage flow.

• 대한기계학회논문집B
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• 제23권8호
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• pp.957-968
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• 1999

Performance tests of an airfoil fan and measurement of flow fields at the impeller exit are carried out to investigate the effects of the tip clearance between the rotor and inlet casing on the impeller performance. The impeller is twelve bladed of NACA 65-810 airfoils and tested with 3 different size of gap; 1, 2, 4mm. The relative decrease of pressure rising performance of the fan is 15 percent for the design flow rate when the gap size is 1 percent of the impeller diameter. The reduction of performance becomes large as the flow rate increases. The leakage flow through the clearance affects the through flow of the impeller, which results in decrease of the slip factor as well as the impeller efficiency. The data base obtained in the present study can be used for the design and flow analysis of the airfoil fans.