• Journal of Environmental Health Sciences
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• v.31 no.5 s.86
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• pp.411-414
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• 2005

Clean Natural is a new disinfectant of which main components are propolis and wood vinegar from Quercus mongolica. The mutagenicity of Clean Natural was studied by a micronucleus test in male ICR mice. The maximally tolerated dose (MTI) of Clean Natural was determined to >2.0 g/kg body weight. Therefore, the doses adopted for the micronucleus test was 2.0 g/kg as a high dose, 1.0 g/kg as a medium and 0.5 g/kg as a low of dose, respectively. Each of group was consisted of three doses of Clean Natural, positive control 2 mg/kg of mitomycin C and negative control 20 ml/kg of saline. A slide preparation was made at 24 hours following administration. No significant induction of micronuclei was observed in any of the three doses of Clean Natural orally administered. No cytotoxicity such as inhibition of hemopoiesis was observed in any group of test agent as the rate of polychromatic erythrocytes to total erythrocytes was over 40%. These results indicate that Clean Natural is not capable of inducing micronuclei in vivo mouse cells and thus has no genotoxicity in micronucleus test.

• Journal of Food Hygiene and Safety
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• v.20 no.3
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• pp.175-178
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• 2005

Clean Natural is a new disinfectant of which main components are propolis and wood vinegar from Quercus mongolica. To evauate the bacterial reverse mutation of Clean Watural, the in vitro Ames test using Salmonella typhimurium TA98, TA100, TA102, TA1535 and TA1537 were performed with clean natural at the concentrations 0, 5, 2.5, and 1.25 mg/ml/plate. Clean Natural was negative in Ames test with Salmonella typhymuyium with and without rat liver microsomal enzyme (S-9 fraction). These results indicate that Clean Watural does not cause bacterial reverse mutation.

• Toxicological Research
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• v.21 no.3
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• pp.263-269
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• 2005

This study was performed to investigate repeated-dose toxicities of Clean natural, a new disinfectant, in Sprague-Dawley(SD) rats. In the 4-week repeated oral toxicity study, Clean Natural was orally administered once daily via gavage to male and female rats at dose levels of 0, 500, 1,000 and 2,000 mg/kg body weight for 4-weeks. There were no deaths and clinical signs during the dosing period. In both sexes, there were no statistically significant differences between the administered and control groups in urinalysis indicators and hematological parameters. In serum biochemistry, aspartate aminotransferase(AST) was significantly decreased and sodium content was increased in the 2,000 mg/kg male group, while chlorine was significantly decreased in the 2,000 mg/kg female group. Also, albumin, total cholesterol and total bilirubin were significantly increased in the 2,000 mg/kg male and female group. In histopathological examinations, centrilobular hepatocellular hypertrophy in the liver was observed in the 2,000 mg/kg male and female groups. And pigmentation in the spleen was observed in the 2,000 mg/kg male group. In conclusion, four-week repeated oral dose of Clean Natural to rats did not cause apparent toxicological change at the dose less than 2,000 mg/kg body weight. Thus it is suggested that no-observed adverse-effect level(NOAEL) for Clean Natural in rats was considered to be 1,000 mg/kg/day.

• The Korean Journal of Ecology
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• v.20 no.5
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• pp.375-384
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• 1997

The effects of three different irrigating water qualities(clean water, life sewage and animal sewage) on the pattern of arthropod communities in the rice fields were investigated at Banwol, Kyonggi-do, mid-western part of Korea from 1994 to 1996. The total density of arthropod was highest in the rice field which was irrigated with clean water(clean water field), and the arthropod community was mainly composed of aphids and collembolans. Each functional group was found in the order of 'pests>non-pests>natural enemies' in its density. The dominant taxa in the pest group were aphids, planthoppers(Delphacidae), leafhoppers(Cicadelidae) and rice water weevil(L. oryzophilus). In the non-pest group collembolans, non-biting midges and dipterans were main arthropods, and in the natural enemy group Araneae was the dominant taxon. In the early growth stage of rice plant the dominant functional group was pests, and in the mid growth stage both the pest and the natural enemy group became dominant. But in the late growth stage none of the functional group was dominant over the other functional groups. The densities of spiders were much more higher in the clean water field than in the other fields. And through all the growth stages of rice plants the density of spiders in clean water field kept increase in contrast to the others. The species composition of spiders in the life sewage field was similar to that in the animal sewage field, but in the clean water field it was different from the other two fields.

• The Pure and Applied Mathematics
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• v.25 no.2
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• pp.115-125
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• 2018

In this paper, we introduce the notion of a clean ordered Krasner hyperring and investigate some properties of it. Now, let (R, +, ${\cdot}$, ${\leq}$) be a clean ordered Krasner hyperring. The following is a natural question to ask: Is there a strongly regular relation ${\sigma}$ on R for which $R/{\sigma}$ is a clean ordered ring? Our motivation to write the present paper is reply to the above question.

• Food Industry And Nutrition
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• v.20 no.1
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• pp.11-14
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• 2015

• Food Science of Animal Resources
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• v.41 no.2
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• pp.173-184
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• 2021

Clean labeling is emerging as an important issue in the food industry, particularly for meat products that contain many food additives. Among synthetic additives, nitrite is the most important additive in the meat processing industry and is related to the development of cured color and flavor, inhibition of oxidation, and control of microbial growth in processed meat products. As an alternative to synthetic nitrite, preconverted nitrite from natural microorganisms has been investigated, and the applications of pre-converted nitrite have been reported. Natural nitrate sources mainly include fruits and vegetables with high nitrate content. Celery juice or powder form have been used widely in various studies. Many types of commercial starter cultures have been developed. S. carnosus is used as a critical nitrate reducing microorganism and lactic acid bacteria or other Staphylococcus species also were used. Pre-converted nitrite has also been compared with synthetic nitrite and studies have been aimed at improving utilization by exploiting the strengths (positive consumer attitude and decreased residual nitrite content) and limiting the weaknesses (remained carcinogenic risk) of pre-converted nitrite. Moreover, as concerns regarding the use of synthetic nitrites increased, research was conducted to meet consumer demands for the use of natural nitrite from raw materials. In this report, we review and discuss various studies in which synthetic nitrite was replaced with natural materials and evaluate pre-converted nitrite technology as a natural curing approach from a clean label perspective in the manufacturing of processed meat products.

• Journal of the Korean Professional Engineers Association
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• v.35 no.1
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• pp.55-59
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• 2002

• 한국가스학회:학술대회논문집
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• 1997.09a
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• pp.33-38
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• 1997

Demand of the clean and convenient natural gas has continuously increased with recognizing of the environment problem since liquefied natural gas was introduced in Korea. Clean fuel natural gas was supplied to each city through high tensile strength pipeline connected by welding. Grades of pipeline were divided into the high and middle pressure according to supply pressure. Pipeline was welded mainly SMA welding process due to its easy handling, the other welding process was adopted according to the constructing condition. We were examined on the microstructure variation and mechanical properties of weld metal for high pressure pipeline, API 5L X-42.

• Rapid Communication in Photoscience
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• v.2 no.2
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• pp.42-45
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• 2013

Natural photosynthesis utilizes solar energy to convert carbon dioxide and water to energy-rich carbohydrates. Substantial use of sunlight to meet world energy demands requires energy storage in useful fuels via chemical bonds because sunlight is intermittent. Artificial photosynthesis research focuses the fundamental natural process to design solar energy conversion systems. Nicotinamide adenine dinucleotide ($NAD^+$) and $NADP^+$ are ubiquitous as electron transporters in biological systems. Enzymatic, chemical, and electrochemical methods have been reported for NADH regeneration. As photochemical systems, visible light-driven catalytic activity of NADH regeneration was carried out using platinum nanoparticles, molecular rhodium and cobalt complexes in the presence of triethanolamine as a sacrificial electron donor. Pt nanoparticles showed photochemical NADH regeneration activity without additional visible light collector molecules, demonstrating that both photoactivating and catalytic activities exist together in Pt nanoparticles. The NADH regeneration of the Pt nanoparticle system was not interfered with the reduction of $O_2$. Molecular cobalt complexes containing dimethylglyoxime ligands also transfer their hydrides to $NAD^+$ with photoactivation of eosin Y in the presence of TEOA. In this photocatalytic reaction, the $NAD^+$ reduction process competed with a proton reduction.