• Animal cells and systems
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• v.1 no.2
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• pp.341-344
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• 1997

Receptor-mediated endocytosis has been suggested for a stage-specific transport mechanism of vitellogenin into the oocytes of a sabellid poly chaete, Pseudopotamilla occelata. Membrane proteins of oocytes of three size classes, including small (30-70 $\mu\textrm{m}$ in diameter), intermediate (70-140 $\mu\textrm{m}$ in diameter) and large (180-200 $\mu\textrm{m}$ in diameter), showed a atage-specific variation. Coelomic fluid proteins (CP), ass$\mu\textrm{m}$ed to be vitellogenin, consists of several proteins, which showed quite a different pattern from that of yolk proteins. Incorporation of $^{125}I$-CP into the oocytes of the intermediate size class almost linearly increases with time, showing a contrast to the pattern of the large size class, in which the incorporation is low and approaches a plateau, suggesting the vitellogenin transports by a regulated process only in the intermediate size class. Vitellogenin receptor proteins were identified to be 60 kDa and 68 kDa only in the intermediate size class by a ligand blotting test.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.10 no.3
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• pp.25-37
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• 2007

The vascular plants of the study area in the Daemisaem region were listed as 302 taxa; 81 families, 196 genera, 251 species, 1 subspecies, 42 varieties, 7 forms and 1 hybrid. Based on the list of Korean endemic plants, 7 taxa were recorded; Carex okamotoi, Salix purpurea var. japonica, Thalictrum uchiyamai, Lespedeza ${\times}$ tomentella, Weigela subsessilis, Aster koraiensis, Cirsium chanroenicum. Specific plants by floral region were total 21 taxa; Silene jenisseensis, Cimicifuga heracleifolia in class IV, 3 taxa (Lilium leichtlinii var. tigrinum, Betula davurica, Lonicera subhispida) in class III, 3 taxa (Viola tokubuchiana var. takedana, Ligularia fischeri, Cirsium chanroenicum) in class II, 13 taxa (Glyceria leptolepis, Meliosma oldhamii, Fraxinus mandshurica, etc.) in class I. The naturalized plants in this site were 8 families, 20 genera, 23 species, 1 varieties, 24 taxa and naturalization rate was 7.9% of all 302 taxa vascular plants. The vegetation community of the selected Daemisaem region were growth of configuration to slope, ridge and valley; Quercus variabilis community, Quercus serrata community, Quercus mongolica community, Salix koreensis community in the slope, Quercus mongolica community, Carpinus tschonoskii community in the ridge, Fraxinus mandshurica community, Carpinus laxiflora community, Acer mono community, Cornus controversa community, Morus bombycis community in the valley.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.7
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• pp.4167-4175
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• 2013

A najor current challenge and constraint in cervical cancer research is the development of vaccines against human papilloma virus (HPV) epitopes. Although many studies are done on epitope identification on HPVs, no computational work has been carried out for high risk forms which are considered to cause cervical cancer. Of all the high risk HPVs, HPV 16, HPV 18 and HPV 45 are responsible for 94% of cervical cancers in women worldwide. In this work, we computationally predicted the promiscuous epitopes among the E6 proteins of high risk HPVs. We identified the conserved residues, HLA class I, HLA class II and B-cell epitopes along with their corresponding secondary structure conformations. We used extremely precise bioinformatics tools like ClustalW2, MAPPP, NetMHC, Epi,Jen, EpiTop 1.0, ABCpred, BCpred and PSIPred for achieving this task. Our study identified specific regions 'FAFR(K)DL' followed by 'KLPD(Q)LCTEL' fragments which proved to be promiscuous epitopes present in both human leukocyte antigen (HLA) class I, class II molecules and B cells as well. These fragments also follow every suitable character to be considered as promiscuous epitopes with supporting evidences of previously reported experimental results. Thus, we conclude that these regions should be considered as the important for design of specific therapeutic vaccines for cervical cancer.

• Journal of Information Technology Services
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• v.6 no.1
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• pp.151-158
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• 2007

D-class computation requires multiplication of three Boolean matrices for each of all possible triples of $n{\times}n$ Boolean matrices and search for equivalent $n{\times}n$ Boolean matrices according to a specific equivalence relation. It is easy to see that even multiplying all $n{\times}n$ Boolean matrices with themselves shows exponential time complexity and D-Class computation was left an unsolved problem due to its computational complexity. The vector-based multiplication theory shows that the multiplication of three Boolean matrices for each of all possible triples of $n{\times}n$ Boolean matrices can be done much more efficiently. However, D-Class computation requires computation of equivalent classes in addition to the efficient multiplication. The paper discusses a theory and an algorithm for efficient D-class computation, and shows execution results of the algorithm.

• International Journal of Advanced Culture Technology
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• v.11 no.3
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• pp.106-112
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• 2023

This study proposes learner participatory activities for learner-centered college liberal arts classes. In addition, it analyzes learners' perceptions of and satisfaction with learner-centered classes and identifies the issues that must be considered when planning learner-centered activities for college liberal arts classes. The study used a learner-centered participatory activity in which participants created a 4-cut cartoon addressing a specific theme. An open-ended questionnaire was administered to identify learners' attitudes about and satisfaction with the learner-centered classes. It showed that most learners (87.5%) were highly satisfied with the 4-cut cartoon creation activities in the learner-centered participatory class. Learners identified the burden- free nature of the class activities, the fact that they improved their understanding of class content, and that they were fun (not boring) as the main reasons they found the class activities satisfying. In liberal arts English classes, more diverse participatory class activities should be developed to arouse interest and motivation of learners and encourage learners' participation.

• Health Policy and Management
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• v.13 no.4
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• pp.99-114
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• 2003

This study was performed to determine the effect of social class distribution as measured by lower social class rate on all cause and cause specific mortality in Korea. I obtained data on social class, fiscal autonomy of municipalities, number of medical doctors, region(Si/Gun) from 1955 Korea Census Data and Regional Statistics Data. And all of the data on mortality adjusted for age for 1995 for each district from the National Statistics Office. Lower social class rate ranged from 18.9％ for Kangnam gu to 85.7％ for Imsil gun and age standardized mortality ranged from 385/100,000 population for Kangnam go to 803/100,000 population for Sinan gun. Lower social class showed had a significant correlation with total mortality adjusted for age(r=0.81, p<0.0001). The association of the rate to total mortality remained highly significant after adjusted for number of medical doctors per 1,000 population, fiscal autonomy of municipalities and region(p<0.0001). Effects of the lower social class were also found for neoplasm (p=0.0008)； cardiovascular disease (p<0.0001)； infectious disease(p=0.0115)； respiratory disease(p=0.0085)； gastrointestinal disease(p<0.0001)； accident ＆ poisoning (p<0.0001). The findings suggest that policies that deal with the inequality in social class may have an important impact on the health of the population.

• Proceedings of the Zoological Society Korea Conference
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• 1994.10a
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• pp.261.1-261
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• 1994

No Abstract, See Full Text

• English Language & Literature Teaching
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• v.12 no.1
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• pp.103-129
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• 2006

This paper presents a case study of the effectiveness of debate class in promoting speaking skills of advanced learners. The researcher adopted English debate techniques in an English speaking class during four-week teacher training program and investigated how teachers responded to the new technique. Forty-five middle and high school teachers participated in the study and classroom observation, pre-survey, post-survey, and focus group interviews were used as the major research methods. The teacher pre-survey results presented that teachers prefer a conversation class where they can directly acquire proper sentence patterns and speaking strategies rather than spend time in performing communicative events. The results of the focus group interview and post-survey confirmed that a debate class can meet this specific teachers' needs. Most teachers responded positively to the debate classes since: 1) debate techniques are relatively new ideas to Korean teachers; 2) debate techniques require speed and accuracy in speech; thus teachers could learn to present their ideas logically and efficiently in a limited time through repeated argument exercises. The study result implies that debate technique can be an effective vehicle in an EFL context to promote advanced learners' logical thinking skills and logical English sentence structures.

• Journal of Engineering Education Research
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• v.23 no.5
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• pp.16-25
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• 2020

This article aims to analyze the experience of designing and operating a class model linking undergraduate and graduate students in engineering education and suggest its development direction. To achieve these objectives, the undergraduate-graduate linked class model was applied to community problem-solving education and a case was analyzed. It also specifically presented the process of how we design the class model and what the actual operational performances and improvements are. This study found that undergraduate and graduate students could build integrated and horizontal cooperative relationships in their classes through undergraduate-graduate linked education and, particularly, graduate students could gain meaningful educational experiences. However, it was difficult to obtain tangible performances through the team activities of these students within a semester. In order for engineering colleges to operate undergraduate-graduate linked education, it would be necessary to provide a longer and more systematic educational environment and better curriculum. The study tried to seek specific tasks and ways to improve them.

• Korean Journal of Veterinary Research
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• v.34 no.2
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• pp.287-299
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• 1994

Plasma protein which has been known as one of nonspecific immunostimulators was added to feedstuff to examine its effect on the enhancement of cellular immune response in porcine immune system. A total of 40 piglets, 20 male and 20 female each, were fed for 30 days with or without plasma protein. The peripheral blood were collected and analyzed for the investigation of leukocyte subpopulations and their activities by using a panel of monoclonal antibodies specific to porcine leukocyte differentiation antigens and flow cytometry. The results obtained as follows. 1. Subpopulations expressing major histocompatibility complex(MHC) class I antigen were $96.2{\pm}3.1%$ and $86.6{\pm}3.8%$ in piglets fed with plasma protein and in piglets fed without plasma protein, respectively. 2. Proportion of leukocyte subpopulation expressing MHC class II antigens were significantly higher in the piglets fed with plasma protein than ones without plasma protein. The proportion was $27.6{\pm}3.6%$ and $16.6{\pm}2.2%$ in MHC class II DQ antigen, and $28.1{\pm}2.0%$ and $20.0{\pm}0.3%$ in MHC class II DR antigen, respectively. 3. A significant increase in the proportion of cells expressing poCD2 was not found in piglets fed plasma protein. 4. Proportion of subpopulation expressed porcine(Po) CD4 antigens which specific to helper T lymphocytes were not increased (18.3-19.1% vs. 25.6-28.8%), rather slightly decreased, in plasma protein-treated group. 5. The most important increase of proportion in plasma protein-treated group was the leukocyte subpopulation specific to $poCD8^+$ T cytotoxic/suppressor lymphocytes. The expression level was significantly higher up to 45.9-47.1% in plasma protein-treated group in comparing with 29.7-33.0% in non-plasma protein-treated group. 6. Lymphoblastogenetic responses using different concentrations of Con A mitogen and plasma protein has found that the responses of lymphocyte from piglets fed plasma protein was significantly activated (p<0.01). The activities measured by 3[H]-thymidine incorporation showed 3-6 times stronger in plasma protein-treated group than those in non-plasma protein-treated group. The study has concluded that plasma protein, which has known as a nonspecific immunostimulator, may have an immunoenhancing activities in porcine lymphoid system by increase the activated cell proportions and their blastogenetic properties which is critical to host immune responses.