• The Journal of Internal Korean Medicine
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• v.25 no.3
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• pp.388-397
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• 2004

Object: This study was designed to investigate the clinical and practical characteristics of stroke patients treated with the age-old herbal medicines, Bojungikki-tang and Bojungikki-tang-gamibang. Methods: The 80 patients studied were all diagnosed with stroke by neurological examination, B-CT and B-MRI scan. They were treated with Bojungikki-tang and Bojungikki-tang-gamibang over 5 days and symptoms were observed. There were inpatients and outpatients at the Oriental Medical hospital of Dong-eui University from January in 2000 to June in 2003. All patients were interviewed and medical charts examined. Result and Conclusion: The results were found: 1.Many were in their sixties. Average age was 64.54. 2.Cerebral infarction was diagnosed in 86.25% of all cases. 3.30% of stroke cases occurred in spring. 4.Average blood pressure was 129/84mmHg on the fifth day of treatment with Bojungikki-tang and Bojungikki-tang-gamibang and 135/86mmHg on the first day. 5.The white color were best in facial color about 85.29%. 6.There were many who returned for treatment within 6 to 10 days. 7.Bojungikki-tang and Bojungikki-tang-gamibang were used Rt. hemiplegia more than for Lt. hemiplegia.

• The Journal of Korean Medicine
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• v.18 no.2
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• pp.245-266
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• 1997

In order to study the effects of Guibitanggamibang on blood pressure and hyperlipidemia, experimental study were performed on hypertension in normal and SHR rats, and on hyperlipidemia induced by Triton WR-1339 in normal rats. Also the level of total cholesterol, triglyceride, LDL-cholesterol, HDL-cholesterol, phospholipid and transaminase(GOT, GPT) were measured. The results are summarized as follows: 1. After Guibitanggamibang was given to normal rats, the results showed that inhibitory effects on blood pressure and heart beat were not statistically significant. 2. After Guibitanggamibang was given to SHR rats, the results showed that inhibitory effects on blood pressure were statistically significant. 3. In the model of hyperlipidemia induced by 2% cholesterol food, Guibitanggarrubang had significantly-decreasing effects on total cholesterol, triglyceride, HDL-cholesterol, LDL-choleste rol, Transaminase(GOT, GPT) level in serum. 4. In the model of hyperlipidemia induced by Triton WR-1339, Guibitanggamibang had significantly-decreasing effects on total cholesterol, triglyceride, LDL-cholesterol, phospholipid, Transaminase(GOT, GPT) level in serum. 5. In the model of hyperlipidemia induced by Triton WR-1339, Guibitanggamibang had no significant effects on HDL-cholesterol level in serum. These results show that Guibitanggamibang(歸脾湯加味方) has significant inhibitory effects on blood pressure and hyperlipidemia and that it could be clinically applied for hypertension and hyperlipidemia.

• The Journal of Internal Korean Medicine
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• v.29 no.1
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• pp.278-284
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• 2008

Objective : The purpose of this clinical study was to investigate the effects of moxibustion on functional recovery in stroke patients. Methods : Forty two stroke patients were randomized into either the standard physiotherapy treatment combined with moxibustion group or a control group with standard physiotherapy alone. They were 8 weeks from onset to the start of this study. Moxibustion was applied at 合谷(LI14), 外關(TE5), 曲池(LI11), 太衝(LIV3), 懸鍾(絶骨,G39), 足三里(S36) in hemiplegic upper and lower extremity, once a day for 6 weeks. The effect of treatment on functional recovery was assessed using the Functional Independence Measure scale. Statistical significance was achieved if the probability was less than 5%(p<0.05). Result : These 2 groups had comparable clinical characteristics; sex, age, lesion, and pre-treatment FIM score. After 6 weeks, patients in the moxibustion group performed better on FIM. The differences were significant(P=0.001). Conclusion : These results suggest that moxibustion is an effective treatment for functional recovery in stroke patients.

• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.3
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• pp.519-524
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• 2010

This clinical study was done to examine comparison the prevalence of metabolic syndrome and obesity index between patients with silent lacunar infarction and normal controls. We compared the components of metabolic syndrome and obesity index between patients silent lacunar infarction(n=62) and normal controls(n=72). The analysis of the data was done by Frequency Analysis, two sample t-test, Chi-square Test. Hypertension and diabetes mellitus was significantly higher in patients of silent lacunar infarctions. Body mass index (BMI), waist-hip ratio (WHR), body fat percentage, obesity ratio, metabolic syndrome were higher significantly in patients of silent lacunar infarctions than normal controls. Although statistically insignificant, waist circumference showed relatively higher in patients of silent lacunar infarction. This result emphasizes the importance of managing that hypertension, diabetes, body mass index (BMI), waist-hip ratio (WHR), body fat percentage, obesity ratio, metabolic syndrome in silent lacunar infarction.

• The Journal of Korean Medicine
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• v.19 no.1
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• pp.251-270
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• 1998

The effects of Gamigunshimtang on the isolated perfused ischemic heart in rats, heart rates, left ventricular pressure, cardiac blood flow and cardiotoxicity were stu.died in H9C2 myoblast cell, myocardial slice culture The results were as follows: 1. The administration of Gamigunshimtang to the rat recovered effectively heart rate, left ventricular pressure and flow rate from the experimental ischemia in perfused rat heart. The release of lactic dehydrogenase after the ischemia also decreased compared to the control group. 2. The administration of Gamigunshimtang to H9C2 myoblast culture enhanced the cell proliferation and protected against doxorubicin and allylamine induced release of the lactic dehydrogenase into the culture medium. It also protected effectively against doxorubicin and allylamine induced decrease of Ca ATPase activity and the increase of NADPH-cytochrome C reductase activity in the microsome. 3. The administration of Gamigunshimtang to the rat myocardial slice culture protected effectively against doxorubicin and allylamine induced decreases of protein synthesis and ATP content, and increases of cvtosolic enzyme, creatin kinase into the medium and lipid peroxidation.

• The Journal of Internal Korean Medicine
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• v.18 no.2
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• pp.229-235
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• 1997

Background and Purpose : The aim of the present study was to investigate the prodromes of stroke in already attacked patients and to prove the traditional hypothesis that some symptoms were to be prodromes of stroke in the oriental medicine. Methods : The questionnaire which was based on symptoms of traditional hypothesis was distributed to subacute stroke patients who were confirmed by Brain CT or MRI in Oriental Medical Hospital, Kyung Hee University, except patients with indistinct onset, symptoms proved any other disease. Results : Eighty-three patients(82.2%) felt some prodromal symptoms and fifty-nine patients (58.4%) underwent a change in their life within one week before onset. Most common prodromal symptoms was the weakness or numbness of limbs, single or unilateral. Conclusion : Our results suggest that the prodromal symptoms before stroke can be regarded as predicting sign. And we think that these research may contribute to preventing stroke and relapse.

• The Journal of Internal Korean Medicine
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• v.22 no.3
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• pp.477-482
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• 2001

Tremor refers to rhythmic shaking of a body part. Tremor is a symptom of many disorders, including Parkinson's disease, essential tremor, orthostatic tremor, cerebellar disease, peripheral neuropathy and alcohol withdrawal. Tremors may be classified as postural, rest or action tremors. Symptomatic treatment is tailored to the tremor type. Because Dansambohyul-tang has been used to treat patients differentiated with an insufficiency of the heart and the spleen(心脾兩虛) in oriental medicine, we treated a 78 year-old female patient who suffered from tremor in mouth, chin and hand and insomnia, with improvement of general condition, who was differentiated with an insufficiency of the heart and the spleen(心脾兩虛) with Dansambohyul-tang, herb complex. After 78 days of treatment with Dansambohyul-tang and some other herb complex, we observed improvement of tremor, insomnia and general condition So Dansambohyul-tang shows therapeutic effects on tremor.

• The Journal of Internal Korean Medicine
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• v.37 no.4
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• pp.661-668
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• 2016

Objectives: To describe the effect of traditional Korean medicine and treatment on Miller Fisher syndrome (MFS).Methods: A 54-year-old woman diagnosed with MFS presented with eyeball dysfunction, diplopia, vertigo, right facial palsy, and back dysesthesia. The patient had been treated with immunoglobulin for 21 d, but her symptoms failed to improve. Thus, herbal medicine, acupuncture, electropuncture, pharmacopuncture, and moxibustion were added. Length of eyeball movement, distance that the patient recognize double images in the eyes and Visual Analogue Scale (VAS) are measures for the syndrome.Results: The symptoms of the patient considerably improved, with the return of eyeball movement to normal and disappearance of diplopia.Conclusions: The results suggest that Korean medicine may be an effective therapy for MFS.

• Journal of The Korean Society of Integrative Medicine
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• v.10 no.4
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• pp.35-47
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• 2022

Purpose : As the number of patients with systemic diseases is increasing in the old, the relevance of oral health is gaining particular research interest. To provide fundamental resources for dental services, this study examined the relationship between doctors' diagnoses of circulatory diseases and patients' awareness of oral health and oral care behaviors. Methods : SPSS 26.0 was used to assess various variables, including doctor's diagnosis of circulatory diseases, gender, age, household income quintile, participation in economic activity, marital status, subjective level of oral health awareness, mastication discomfort, speaking and chewing discomfort, dental inspection, use of oral care goods, teeth brushing during the previous day, and untreated oral conditions. Results : The circulatory diseases suffered by the subjects were as follows: 56 % high blood pressure, 36 % dyslipidemia, 6 % stroke, and 8 % myocardial infarction or angina. A higher age meant a higher diagnosis rate of high blood pressure (p<.001) and stroke (p<.001). Those with dyslipidemia showed a higher rate of receiving oral inspection (p=.040), and an untreated oral condition was more frequently observed among those not diagnosed with the disease (p=.035). The subjects who were not diagnosed with stroke showed a higher rate of oral inspection (p<.001), while those who had a prior experience of stroke suffered a higher rate of mastication discomfort (p=.020). People who had high blood pressure showed a lower rate of using oral care goods (p<.001), and those diagnosed with stroke showed a lower rate of brushing teeth the previous day. Conclusion : This study found a correlation between the diagnosis of circulatory diseases and the awareness of oral health and oral care behavior. Consequently, oral health education should be included in mental health-related education, and customized training to teach teeth brushing and the use of oral care goods should be provided to patients with circulatory diseases during dentist visits.

• The Journal of the Society of Stroke on Korean Medicine
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• v.14 no.1
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• pp.115-121
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• 2013

A 67 year-old Taeeumin(太陰人) female patient with Thalamic pain Syndrome(Dejerine-Roussy Syndrome) was treated. She was suffering from rt. side numbness, pain and weakness, rt. facial palsy, dizziness, dysarthria and lassitude. She was diagnosed as Cerebral lacunar infarction(Lt. thalamus) by Brain MRI(Magnetic Resonance Imaging) and adminstered Yeoldahanso-tang(熱多寒少湯). After taking Yeoldahanso-tang(熱多寒少湯), her symptoms had improved. Result suggest that Yeoldahanso-tang(熱多寒少湯) is an effective for Taeeumin Thalamic pain Syndrome. Though, results support a role for oriental medical treatment for Cerebrovascular Accident(CVA) connected Sasang Constitution, further research into the effectiveness of oriental medical treatments for CVA connected Sasang Constitution is needed.