• Title/Summary/Keyword: Circular cavity

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Complete genome sequence of Neisseria sp. KEM232 isolated from a human smooth surface caries (사람 평활면 치아우식에서 분리한 Neisseria sp. KEM232 균주의 유전체 서열 분석)

  • Kim, Eun Mi;Seong, Chi Nam
    • Korean Journal of Microbiology
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    • v.54 no.1
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    • pp.81-83
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    • 2018
  • We sequenced the genome of the Neisseria sp. KEM232 isolated from the smooth surface caries of human cavity of a 7-year old male in Republic of Korea by using the standard dilution plating technique. The genome comprises a single circular 2,371,912 bp chromosome with a G + C content of 58.5%, 2,210 protein-coding genes, 108 pseudo genes, 51 RNA genes, and one CRISPR array. Based on the 16S rRNA gene sequence similarity and average nucleotide identity, the strain KEM232 is most closely related to Neisseria baciliformis.

Functional annotation of uncharacterized proteins from Fusobacterium nucleatum: identification of virulence factors

  • Kanchan Rauthan;Saranya Joshi;Lokesh Kumar;Divya Goel;Sudhir Kumar
    • Genomics & Informatics
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    • v.21 no.2
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    • pp.21.1-21.14
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    • 2023
  • Fusobacterium nucleatum is a gram-negative bacteria associated with diverse infections like appendicitis and colorectal cancer. It mainly attacks the epithelial cells in the oral cavity and throat of the infected individual. It has a single circular genome of 2.7 Mb. Many proteins in F. nucleatum genome are listed as "Uncharacterized." Annotation of these proteins is crucial for obtaining new facts about the pathogen and deciphering the gene regulation, functions, and pathways along with discovery of novel target proteins. In the light of new genomic information, an armoury of bioinformatic tools were used for predicting the physicochemical parameters, domain and motif search, pattern search, and localization of the uncharacterized proteins. The programs such as receiver operating characteristics determine the efficacy of the databases that have been employed for prediction of different parameters at 83.6%. Functions were successfully assigned to 46 uncharacterized proteins which included enzymes, transporter proteins, membrane proteins, binding proteins, etc. Apart from the function prediction, the proteins were also subjected to string analysis to reveal the interacting partners. The annotated proteins were also put through homology-based structure prediction and modeling using Swiss PDB and Phyre2 servers. Two probable virulent factors were also identified which could be investigated further for potential drug-related studies. The assigning of functions to uncharacterized proteins has shown that some of these proteins are important for cell survival inside the host and can act as effective drug targets.

Paper-based Electrochemical Sensor Using a Self-operated Paper Pump (자발 구동형 종이 펌프를 이용한 종이 전기화학 센서)

  • Si Hiep Hua;Chikwan Kim;Duc Cuong Nguyen;Yong Shin Kim
    • Journal of Sensor Science and Technology
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    • v.33 no.3
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    • pp.158-164
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    • 2024
  • We developed a self-operated paper pump that can maintain a nearly constant flow rate of an aqueous solution along a paper strip channel in paper-based analytical devices (PADs). The quasi-stationary flow rate was controlled by increasing the crosssectional channel area (capillary force) using a fan-shaped absorption pad coupled with a paper strip channel. The flow rate is regulated by varying the fan angle of the circular absorbing pad. Furthermore, the flow rate can be increased by furnishing a hollow cavity at the center of a conventional paper strip channel. The rate was regulated by varying the length of the hollow paper channel in the flow rate range of 5.1-26.4 mm/min. As a preliminary work, a paper-pump-coupled PAD was fabricated, and its CV detection capability was evaluated for the redox reaction of Fe(CN)6+4/+3. The combination of a paper pump with a PAD resulted in an ideal CV curve with a higher limiting current and faster response time. These results are interpreted well by the Levich equation, which suggests that the paper pump is a very useful component in paper-based sensors.

Ultrasonographic Appearance of Postpartum Uterine Involution in Small Pet Dogs (소형 애완견에서 분만후 자궁수복의 초음파상)

  • 손창호;김혜령;김정훈;정경아;이주환;오기석;박인철;박상국;김성호
    • Journal of Veterinary Clinics
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    • v.18 no.2
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    • pp.139-145
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    • 2001
  • This study was undertaken to determine the normal serial ultrasonographic appearance of the postpartum uterine involution in small pet dogs (Yorkshire terrier and Maltese). Postpartum changes in uterine shape, architecture, echogenicity and diameter were monitored by ultrasonography in 12 small pet dogs. Serial ultrasonographic examinations were done daily during the first week, 3 days interval from 8 to 30 days, and weekly from 31 to 100 days postpartum. The excretory period of vaginal discharge in 12 normal bitches of uterine involution was finished completely within 3 weeks postpartum. The short axis shape of the uterus was initially often flaccid-appearing. It varied from circular to polygonal. This lasted until 15.75$\pm$3.84 days postpartum, during which time the short axis uterine shape gradually changed to circular. Also, the long axis shape of the uterus was a beaded appearance until 30.89$\pm$4.25 days postpartum. After 30 days, it was appeared as tubular shape between placental and interplacental sites. The ultrasonographic image of the postpartum uterus consisted of four echogenicity distinct layers. Uterine wall was represented as very hyperechoic serosa, hypoechoic myometrium, hyperechoic endometrium and anechoic structures of fluid in the uterine cavity until 7 days postpartum. The individual uterine layers were most prominent during the first week postpartum, and they became progressively less distinct throughout the course of uterine involution. The thickness of myometrium was decreased rapidly in the placental sites from 4.47$\pm$1.42 mm at 1 day to 1.92$\pm$0.26 mm at 16 day, and in the interplacental sites from 3.19$\pm$0.61 mm at 1 day to 1.39$\pm$0.61 mm at 16 day. And it was decreased slowly until 94 day and was been minimum thickness at 94 day. The thickness of endometrium was also decreased like that of myometrium. The uterine diameter in the placental sites was decreased from 22.28$\pm$3.01 mm at 1 day to 16.11$\pm$1.46 mm at 7 day, and in the interplacental sites was decreased from 13.65$\pm$2.34 mm at 1 day to 9.41$\pm$1.59 mm at 7 day postpartum. From 7 day to 93 day, the change of diameter was more and more slow. At 94 days postpartum, the uterine diameter was 5~6 mm both placental and interplacental sites, and the uterine horns were uniform hypoechoic, tubular structures without enlargement. Therefore, complete involution of the uterus occurred at 94 days. It was concluded that normal post partum uterine involution in small pet dogs appeared to be completed 94 days postpartum by gross findings such as vaginal discharges, and by ultrasonographic findings, uterine shape and echogenicity.

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Multipaction Sensitivity Analysis of X-band Output Filter for Geostationary Satellite (정지궤도위성 X-대역 출력필터 멀티팩션 민감도 해석)

  • Kim, Joong-Pyo;Lee, Sun-Ik;Lim, Won-Gyu;Kim, Sang-Goo;Lee, Sang-Kon
    • Journal of Satellite, Information and Communications
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    • v.10 no.3
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    • pp.131-136
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    • 2015
  • In this paper, prior to the flight model X-band dual-mode circular cavity filter required for the high power transmission of the observation payload in the geostationary satellite, the development model are designed and analyzed to show the analytical multipactor requirement margin. First of all, the multipaction breakdown power sensitivities were analyzed by changing the iris width and thickness within the filter, and through that the iris width and thickness was selected and then the multipaction threshold powers over the frequencies within the bandwidth were analyzed and the required margin of 8 dB was obtained. Also for the high power transmission filter, another important phenomena known as corona breakdown are analyzed for the iris width and thickness changes. Finally the development model manufactured was tested and the results met the key requirements.

A Study on the Improvement of the Directivity for Rectangular Microstrip Patch Array Antennas Conformed to a Cylindrical Surface (원통면에 정합-배열된 장방형 마이크로스트립 패치 안테나의 지향성 개선을 위한 연구)

  • 고광태;구연건
    • The Proceeding of the Korean Institute of Electromagnetic Engineering and Science
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    • v.5 no.2
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    • pp.46-54
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    • 1994
  • In this paper, an analysis and design method is proposed, which is to improve the directivity of microstrip array antennas conformed to a cylindrical surface. In the case of forming an arc-array in the circumferential direction on a circula-cylinder surface, the circular-cylinder can be approximated to a polygonal-pillar and on each pillar-planes the sub-arrays, Dolph-Tschebyscheff array and uniform array with a beam steered in the desired direction, would make a sharp directivity for the total cylin- drical array antenna. And the radiation pattern according to the type of its sub arrays is analyzed and compared using the cylindrical-cavity codel. A cylindrical microstrip array antenna, with 12 elements and uniform arra as a sub-array which have an equal distance$\lambda_0$/2between the elements, is manufactured and conformed to a cylinder with radius of 6 The measured data of side lobe level, HPBW and FNBW are - 13dB, $9^{\circ}$, and $15{\circ}$, ,respectively. This result shows a good improvement on the directivity comparing with a linear array.

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NATURAL CONVECTION IN A TRIANGULAR POOL WITH VOLUMETRIC HEAT GENERATION (삼각형 형상의 풀 내에서 열원에 의한 자연대류 수치해석)

  • Kim, Jong-Tae;Park, Rae-Joon;Kim, Hwan-Yeol;Song, Jin-Ho
    • 한국전산유체공학회:학술대회논문집
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    • 2011.05a
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    • pp.302-310
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    • 2011
  • A fluid in an enclosure can be heated by electric heating, chemical reaction, or fission heat. In order to remove the volumetric heat of the fluid, the walls surrounding the enclosure must be cooled. In this case, a natural convection occurs in the pool of the fluid, and it has a dominant role in heat transfer to the surrounding walls. It can augment the heat transfer rates tens to hundreds times larger than conductive heat transfer. The heat transfer by a natural convection in a regular shape such as a square cavity or semi-circular pool has been studied experimentally and numerically for many years. A pool of an inverted triangular shape with 10 degree inclined bottom walls has a good cooling performance because of enhanced boiling critical heat flux (CHF) compared to horizontal downward surface. The coolability of the pool is determined by comparing the thermal load from the pool and the maximum heat flux removable by cooling mechanism such as radiative or boiling heat transfer on the pool boundaries. In order to evaluate the pool coolability, it is important to correctly expect the thermal load by a natural convection heat transfer of the pool. In this study, turbulence models with modifications for buoyancy effect were validated for unsteady natural convections by volumetric heating. And natural convection in the triangular pool was evaluated by using the models.

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HIGH Ra NUMBER NATURAL CONVECTION IN A TRIANGULAR POOL WITH A HEAT GENERATION (열원이 있는 삼각형 풀의 높은 Ra수 자연대류)

  • Kim, Jong-Tae;Park, Rae-Joon;Kim, Hwan-Yeol;Hong, Seong-Wan;Song, Jin-Ho;Kim, Sang-Baik
    • Journal of computational fluids engineering
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    • v.16 no.3
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    • pp.66-74
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    • 2011
  • A fluid in an enclosure can be heated by electric heating, chemical reaction, or fission heat. In order to remove the volumetric heat of the fluid, the walls surrounding the enclosure must be cooled. In this case, a natural convection occurs in the pool of the fluid, and it has a dominant role in heat transfer to the surrounding walls. It can augment the heat transfer rates tens to hundreds times larger than conductive heat transfer. The heat transfer by a natural convection in a regular shape such as a square cavity or semi-circular pool has been studied experimentally and numerically for many years. A pool of an inverted triangular shape with 10 degree inclined bottom walls has a good cooling performance because of enhanced boiling critical heat flux (CHF) compared to horizontal downward surface. The coolability of the pool is determined by comparing the thermal load from the pool and the maximum heat flux removable by cooling mechanism such as radiative or boiling heat transfer on the pool boundaries. In order to evaluate the pool coolability, it is important to correctly expect the thermal load by a natural convection heat transfer of the pool. In this study, turbulence models with modifications for buoyancy effect were validated for unsteady natural convections by volumetric heating. And natural convection in the triangular pool was evaluated by using the models.

Serial Ultrasonographic Evaluation of Postpartum Uterine Involution in Miniature Schnauzer Dogs

  • Yeo, Woon-Chang;Kim, Bang-Sil;Yun, Chang-Jin;Park, Chul-Ho;Kim, Jung-Bae;Moon, Jin-San;Suh, Guk-Hyun;Oh, Ki-Seok;Son, Chang-Ho
    • Journal of Embryo Transfer
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    • v.22 no.4
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    • pp.229-234
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    • 2007
  • This study was undertaken to determine the normal appearance of the postpartum uterine involution. Postpartum changes in uterine shape, architecture, echogenicity and diameter were monitored with ultrasonography in 8 Miniature Schnauzer dogs. Vaginal discharge was observed visually during the 3 weeks of postpartum. A large amount of viscous dark green discharge changed progressively to a small amount of transparent discharge. In the uterine shape, the transverse images were crescent or polygonal at the beginning, but became circular after 16 days. At postpartum day 24, the longitudinal images of placental and interplacental sites were similar to each other The echogenicity of uterine structure was clearly distinguishable among the hyperechoic serous membrane, hypochoic myometrium, hyperechoic endometrium, and anechoic uterine contents during the first week postpartum, but afterward the interluminal boundaries and echogenicity became obscure gradually. In addition, the anechoic substance of the endometrial cavity was not observed after postpartum day 28. In the uterine diameter, the diameter of placental sites decreased markedly from 24 mm at the first day postpartum to 13 mm at day 7, and the diameter of interplacental sites decreased from 15 mm at postpartum day 1 to 10 mm at day 7. At postpartum day 65, the uterus (6.4 mm) changed little and had a uniform homogenous echo, and thus it was confirmed that uterine involution was completed at that time in Miniature Schnauzer dogs.

Post-endodontic Restoration on Erupting Permanent First Molars Using Endocrown with a Polyglass Composite Resin: Report of Two Cases (맹출 중인 제1대구치의 근관 치료 후 엔도크라운을 통한 수복 증례 보고)

  • Jeong, Hyuntae;Kim, Seonmi;Kim, Jaehwan;Choi, Namki
    • Journal of the korean academy of Pediatric Dentistry
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    • v.46 no.1
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    • pp.111-118
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    • 2019
  • Post-endodontic restorations are both important and challenging for clinical success in endodontically treated posterior teeth. Several options have been proposed to restore endodontically treated molars. In pediatric dentistry, restoration using conventional single crowns, especially for partially erupted molars with insufficient retentive tooth structure, has proven to be difficult. However, the endocrown presents a conservative and esthetic restorative alternative to conventional crowns with post-and-core, as it acquires additional retention within the pulp chamber. The tooth preparation consists of a circular, equigingival, butt-joint margin and a central retention cavity in the pulp chamber that helps to construct both the crown and core as a single unit. This case report describes the esthetic and conservative endocrown restorations of erupting permanent first molars with extensive coronal destruction.