• Analytical Science and Technology
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• v.34 no.2
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• pp.87-98
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• 2021

In this study, we developed the nanoparticle multi-generator by 3D printer fusion deposition modeling (FDM) method that can reliably generate and deliver nanoparticles at a constant concentration for inhalation risk assessment. A white ABS filament was used as the test material, and SMPS was used for concentration analysis such as particle size and particle distribution. In the case of particle size, the particle size was divided by 100 nm or less and 100 to 1,000 nm, and the number of particles concentration, mass concentration, median diameter of particles, geometric average particle diameter, etc were measured. The occurrence conditions were the extruder temperature, the extruding speed of the nozzle, and the air flow rate, and experiments were conducted according to the change of conditions including the manufacturer's standard conditions. In addition, the utility of inhalation risk assessment was reviewed through a stability maintenance experiment for 6 h. As a result of the experiment, the size of the nanoparticles increased as the discharger temperature increased, as the discharge speed of the nozzle increased, and as the air flow rate decreased. Also, a constant pattern was shown according to the conditions. Even when particles were generated for a long time (6 h), the concentration was kept constant without significant deviation. The distribution of the particles was approximately 80 % for particles of 60 nm to 260 nm, 1.7 % for 1 ㎛ or larger, 0.908 mg/㎥ for the mass concentration, 111 nm for MMAD and 2.10 for GSD. Most of the ABS particles were circular with a size of less than 10 nm, and these circular particles were aggregated to form a cluster of grape with a size of several tens to several hundred nm.

• Journal of the Korean Magnetic Resonance Society
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• v.24 no.4
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• pp.136-142
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• 2020

Apolipoprotein B-100 (apo B-100), the main protein component that makes up LDL (Low density lipoprotein), consists of 4,536 amino acids and serves to combine with the LDL receptor. The oxidized LDL peptides by malondialdehyde (MDA) or acetylation in vivo were act as immunoglobulin (Ig) antigens and peptide groups were classified into 7 peptide groups with subsequent 20 amino acids (P1-P302). The biomimetic peptide P99 (KGTYG LSCQR DPNTG RLNGE) out of B-group peptides carrying the highest value of IgM antigens were selected for structural studies that may provide antigen specificity. Circular Dichroism (CD) spectra were measured for peptide secondary structure in the range of 190-260 nm. Experimental results show that P99 has pseudo α-helice and random coil structure. Homonuclear (COSY, TOCSY, NOESY) 2D-NMR experiments were carried out for NMR signal assignments and structure determination for P99. On the basis of these completely assigned NMR spectra and proton distance information, distance geometry (DG) and molecular dynamic (MD) were carried out to determine the structures of P99. The proposed structure was selected by comparisons between experimental NOE spectra and back-calculated 2D NOE results from determined structure showing acceptable agreement. The total Root-Mean-Square-Deviation (RMSD) value of P99 obtained upon superposition of all atoms were in the set range. The solution state P99 has mixed structure of pseudo α-helix and β-turn(Gln[9] to Thr[13]). These NMR results are well consistent with secondary structure from experimental results of circular dichroism. Structural studies based on NMR may contribute to the prevent oxidation studies of atherosclerosis and observed conformational characteristics of apo B-100 in LDL using monoclonal antibodies.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.29 no.5A
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• pp.421-431
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• 2009

This paper is the study on the verification of structural health monitoring (SHM) algorithm based on the ultrasonic guided wave. An active inspection system using Lamb wave (LW) for SHM was considered. The basic study about the application of this algorithm was performed for detecting the circular notch defect in steel plate. LW testing technique, pitch-catch method, was used for interpretation of circular notch defect with depth of 50% of plate thickness and 7 mm width. Damage characterization takes place by comparing $S_0$ mode sensor signals collected before and after the damage event. By subtracting the signals of both conditions from each other, a scatter signal is produced which can be used for damage localization. The continuous Gabor wavelet transform is used to attain the time between the arrivals of the scatter and sensor signals. A new practical damage monitoring algorithm, based on damage monitoring polygon and pitch-catch method, has been proposed and verified with good accuracy. The possible damage location can be estimated by the average on calculated location points and the damage extent by the standard deviation.

• Tunnel and Underground Space
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• v.13 no.5
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• pp.397-402
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• 2003

Generally it is likely that rock mass properties are expressed not by a mean value but by values with variation due to its characteristic uncertainty. This characteristic is one of the most important parts for the design of undergound structures, but yet to be fully examined. Stochastic finite element method (SFEM) is contrary to deterministic finite element method in its concept as the former has been developed in order to take the randomness of structural systems into account. Using SFEM, the response variability of structural system can be obtained and it leads probabilistic stability of structure to be analyzed. In this study, displacement response variability of circular opening with hydrostatic stress field are analyzed in terms of rock mass properties having a certain mean and a standard deviation using the SFEM. The analyzed response variability shows that the necessity of probabilistic stability analysis of underground structures using reliable mean value and standard deviation of deformation modulus.

• Korean Institute of Interior Design Journal
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• v.15 no.6 s.59
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• pp.77-88
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• 2006

According to critics and architects, non-linear structure is not only an organic form of space, but also a form of space detached from modem style. Accordingly, non-linear structure can be accepted as an alternative to what has remained unsolved by deconstructionist. However, they are criticized for not clarifying the interdependent relationship between non-linearity of space and cognitive structure of human being. They ended up remaining the hypothesis just an intuitive and abstract one. This research began on the basis that their hypothesis is hard to be objectified, and it needs further inquiry. The purpose of this thesis is to explore how the redundant factors constitute non-linear structures of digital media centered space design. Geometric compositions of space structure were analyzed to define what types of redundant factors are contrived in the process of visual information. This study about the visual form, researching the Information Theory, and then offer a quantitative analysis that makes those more objective. Space structure and geometric composition were analyzed to define what types of redundancy are contrived in the process of visual information. In particular, I put higher theoretical emphasis on what characteristics are ensued in the process of structuring spaces than any other subjects. Followings are the conclusion of analysis. First, as a result of examining, we can assume that NOX' space structure is not a chaotic form, but has an operating the form of its own. Second, in case of curvilinear, the structure was found redundancy on mid deviation ratio and discontinuous circular fabric. Although most of their structures appeared complex with a higher coherent constant, they were found to be stable factors because of the low deviation ratio between systems. The amount of surplus information was stable structure as well.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.21 no.7
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• pp.1166-1173
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• 1997

Due to progress in manufacturing techniques, the performance of the harmonic drive has been improved but not sufficiently. One of the important problems which the current harmonic drive has is that while there is the potential for having a wider tooth contact area, the total number of teeth engaged simultaneously is still small. This is mainly due to the involute tooth profile. Hence, in this study, the cycloid-type tooth profile is developed to improve this problem. This paper represents the design methodology and performance evaluation f the cycloid-type harmonic drive. Cycloide tooth profile was derived by analyzing geometry of the tooth engagement and the contact mechanisms of the tooth which were examined and analyzed by load analysis. The stress due to elastic deformation of a flexspline was also obtained by approximate formula and computer analysis. Finally, the cycloid-type harmonic drive with 1:100 speed ratio was manufactured and the performance of the harmonic drive was evaluated.

• Transactions of the Korean Society of Mechanical Engineers
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• v.15 no.1
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• pp.154-162
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• 1991

In this study, the simulation program is developed where the tooth profile error in internal gear shaping is calculated considering several factors which affect it. This factors are the circular feed of the pinion cutter, the interference by the geometric conditions of the cutter and the internal gear, the deviation from the theoretical involute profile of the cutter and the eccentricity of the cutter and the internal gear. With this program, the effects are investigated which the geometric conditions and the cutting conditions in internal gear shaping have on the tooth profile error of the internal gear. The condition for the minimization of it is derived and then the results of simulation are adequately verified by measurements of internal gears cut by a pinion cutter.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.48 no.3
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• pp.235-241
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• 2012

The efficiency tests of automatic positioning transmitter (APT) using satellite on life jacket were carried out to minimize casualties of fishermen and to make system optimization for effective SAR (Search and Rescue) operation. As the result of the tests, average position was equaled on the comparison between SPOT using low earth orbit satellite and DGPS (Differential Global Positining System), but standard deviation of DGPS for latitude and longitude were 66.4% and 46.3% smaller than those of SPOT. The position precision of SPOT was almost two times lower than LGT using geostationary satellite to compare 95% circular error probability. However, the success rate of receiver for SPOT was revealed as 86.5~94.1% on the experiments in the South Sea and the West Sea and it was 4.5 times higher than LGT. Therefore, SPOT is expected to contribute greatly to the rapid rescue of victim.

• Proceedings of the SAREK Conference
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• 2009.06a
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• pp.804-809
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• 2009

The present study measured frost pattern on a cylinder to propose empirical correlation equations for the local and average frost thickness, frost density and frost mass. The key parameters were diameter of the cylinders (7mm, 20mm), cooling surface temperature of the circular tube, absolute humidity of air, air temperature and air velocity. A 50% ethylene glycol aqueous solution was applied as a coolant. The frost thicknesses at both front and rear were larger than those at the other parts, while they were increased as diameter of the cylinder was increased. The local frost thicknesses at high air velocity were more uniform than those at low air velocity. The values predicted by Kim et al. under the freezer condition showed larger by the maximum of $30{\sim}50%$ than the measured data under heat pump condition. The empirical correlations for the local and average frost thickness and frost mass were proposed. The correlation equations for the frost thickness and frost mass under the heat pump condition in the present study might predict more accurate than the other correlation equations. The proposed correlations might be applied for the freezer condition within the maximum 15% deviation from the previous correlations under freezer condition.

• Advances in materials Research
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• v.6 no.2
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• pp.155-168
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• 2017

The terrorist attacks and dangers by bomb blast have turned into an emerging issue throughout the world and the protection of the people and structures against terrorist acts depends on the prediction of the response of structures under blast and shock load. In this paper, behavior of aluminum and unidirectionally reinforced E-Glass Epoxy composite plates with and without focal circular holes subjected to shock loading has been identified. For isotropic and orthotropic plates (with and without holes) the classical normal mode approach has been utilized as a part of the processing of theoretical results. To obtain the accurate results, convergence of the results was considered and a number of modes were selected for plate with and without hole individually. Using a shock tube as a loading device, tests have been conducted to composite plates to verify the theoretical results. Moreover, peak dynamic strains, investigated by experiments are also compared with the theoretical values and deviation of the results are discussed accordingly. The strain-time histories are likewise indicated for a specific gauge area for aluminum and composite plates. Comparison of dynamic-amplification factors between the isotropic and the orthotropic plates with and without hole has been discussed.