• Proceedings of the SAREK Conference
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• 2009.06a
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• pp.1129-1134
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• 2009

A numerical study has been conducted to investigate the effect of tube arrangement on the heat transfer and the pressure loss for cross flow heat exchangers. By defining a transverse deviation factor, ${\varepsilon}_t=l_T/S_T$, the flow pattern and the heat transfer characteristics are compared for selected ${\varepsilon}_t$ values of 0.0(in-lined), 0.1, 0.2, 0.3, 0.4, 0.5(staggered) by using a commercial software. Computational domain includes 1 pitch in the transverse direction and 5 pitches in the flow direction with due periodic boundary conditions.

• Transactions of Materials Processing
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• v.10 no.2
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• pp.130-136
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• 2001

The mathematical set-up model was developed to reduce the mechanical property deviation in annealed and slightly rolled steel strip. The mechanical peculiarities of skin pass rolling process, such as high friction value and non-circular contact arc, low reduction and non-negligible entry and exit elastic zones as well as central restricted deformation zone are all taken into account. The deformation of work rolls is calculated with the influence function method and arbitrary contact arc shape is permitted. The strip deformation is modeled by slab method and the entry and exit elastic deformation zones are included. The strip restricted deformation zone near the neutral point is also considered. It was revealed that the new model has better accuracy than present regression model by statistical analysis with actual mill rolling data.

• 제어로봇시스템학회:학술대회논문집
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• 2000.10a
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• pp.317-317
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• 2000

The mathematical set-up model was developed to reduce the mechanical property deviation in annealed and slightly rolled steel strip. The mechanical peculiarities of temper rolling process, such as high friction value and non-circular contact arc, Low reduction and non-negligible entry and exit elastic zones as well as central restricted deformation zone are all taken into account. The deformation of work rolls is calculated with the influence function method and arbitrary contact arc shape is permitted. The strip deformation is modeled by slab method and the entry and exit elastic deformation zones are included. The restricted deformation Bone near the neutral point is also considered. It was revealed that the new model has better accuracy than present regression model by statistical analysis with actual mill rolling data.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2006.05a
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• pp.243-244
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• 2006

In this paper, the development of an error measurement system of 5-axis mill & turn machine tool presented by double ball bar test, which has been widely used to measure the overall accuracy of machining center. and the reliability of an error measurement system of 5-axis mill & turn machine tool was secured by the direct cutting test.

• Bulletin of the Korean Chemical Society
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• v.17 no.4
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• pp.358-362
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• 1996

The ionic strength dependent binding mode of 9-aminoacridine (9AA), a well-known DNA intercalator, to DNA is studied by flow linear dichroism, circular dichroism, fluorescence techniques and equilibrium dialysis. The DNA-bound 9AA exhibits spectral properties corresponding to the intercalative binding mode disregarding the salt concentrations; the angle between the long-axis transition moment of the 9AA molecule and DNA helix axis is calculated to be about 65°, indicating a significant deviation from the classical intercalation. At low salt concentrations, however, upwards bending curve in Stern-Volmer plot is observed (where 9AA is a fluorophore and DNA a quencher), indicating the coexistence of both static and dynamic quenching mechanisms or the existence of an additional binding site.

• Design & Manufacturing
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• v.17 no.1
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• pp.20-26
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• 2023

Lab-on-a-disc is a circular disc shape of cartridge that can be used for blood-based liquid biopsy to diagnose an early stage of cancer. Currently, liquid biopsies are regarded as a time-consuming process, and require sophisticated skills to precisely separate cell-free DNA (cfDNA) and circulating tumor cells (CTCs) floating in the bloodstream for accurate diagnosis. However, by applying the lab-on-a-disc to liquid biopsy, the entire process can be operated automatically. To do so, the lab-on-a-disc should be designed to prevent blood leakage during the centrifugation, transport, and dilution of blood inside the lab-on-a-disc in the process of liquid biopsy. In this study, the main components of lab-on-a-disc for liquid biopsy are fabricated by injection molding for mass production, and ultrasonic welding is employed to ensure the bonding strength between the components. To guarantee accurate ultrasonic welding, the flatness of the components is optimized numerically by using the response surface methodology with four main injection molding processing parameters, including the mold & resin temperatures, the injection speed, and the packing pressure. The 27 times finite element analyses using Moldflow® reveal that the injection time and the packing pressure are the critical factors affecting the flatness of the components with an optimal set of values for all four processing parameters. To further improve the flatness of the lab-on-a-disc components for stable mass production, a quarter-disc shape of lab-on-a-disc with a radius of 75 mm is used instead of a full circular shape of the disc, and this significantly decreases the standard deviation of flatness to 30% due to the reduced overall length of the injection molded components by one-half. Moreover, it is also beneficial to use a quarter disc shape to manage the deviation of flatness under 3 sigma limits.

• Steel and Composite Structures
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• v.26 no.4
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• pp.485-499
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• 2018

In this paper, a hollow steel tube (HST) shear connector is proposed for use in a slim-floor system. The HST welded to a perforated steel beam web and embedded in concrete slab. A total of 10 push-out tests were conducted under static loading to investigate the mechanical behavior of the proposed HST connector. The variables were the shapes (circular, square and rectangular) and sizes of hollow steel tubes, and the compressive strength of the concrete. The failure mode was recorded as: concrete slab compressive failure under the steel tube and concrete tensile splitting failure, where no failure occurred in the HST. Test results show that the square shape HST in filled via concrete strength 40 MPa carried the highest shear load value, showing three times more than the reference specimens. It also recorded less slip behavior, and less compressive failure mode in concrete underneath the square hollow connector in comparison with the circular and rectangular HST connectors in both concrete strengths. The rectangular HST shows a 20% higher shear resistance with a longer width in the load direction in comparison with that in the smaller dimension. The energy absorption capacity values showed 23% and 18% improvements with the square HST rather than a headed shear stud when embedded in concrete strengths of 25 MPa and 40 MPa, respectively. Moreover, an analytical method was proposed and predicts the shear resistance of the HST shear connectors with a standard deviation of 0.14 considering the shape and size of the connectors.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.26 no.3
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• pp.432-438
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• 2002

In order to design and analyze the performance of an axial-flow pump it is necessary to know the flow deviation, deflection angle and pressure loss coefficient as a function of the angle of incidence for the hydrofoil section in use. Because such functions are unique to the particular section, however, general correlation formulae are not available for the multitude of hydrofoil profiles, and such functions must be generated by either experiment or numerical simulation for the given or selected hydrofoil section. The purpose of present study is to generate design correlations for hydrofoils with double circular arc (DCA) camber by numerical analysis using a commercial code, FLUENT. The cascade configuration is determined by a combination of the inlet blade angle, blade thickness, camber angle, and cascade solidity, and a total of 90 cascade configurations are analyzed in this study. The inlet Reynolds number based on the chord and the inlet absolute velocity is fixed at 5${\times}$10$\^$5/. Design correlations are formulated, based on the data at the incidence angle of minimum total pressure loss. The correlations obtained in this way show good agreement with the experiment data collected at NASA with DCA hydrofoils.

• Journal of Radiation Protection and Research
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• v.28 no.1
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• pp.19-24
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• 2003

The self-attenuation factor for an $^{198}Au$ sample and the 0.412 MeV gamma-ray penetration ratio in the circular Al-cover of the radiation detector have been determined using an analytical solution and MCNP code. The results show that the self-attenuation factors obtained from the analytical solution coincide with those of MCNP code for all but the Au sample with the relatively larger radius. Then the maximum difference between the two methods appears to be 9 % in the Au sample of 1.5 mm radius. It also is revealed that the analytical solutions of the 0.412 MeV gamma-ray penetration ratio in the Al-cover of 7.62 cm radius are consistent with those of the MCNP code within the standard deviation.

• Journal of the Korean Magnetic Resonance Society
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• v.20 no.3
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• pp.95-101
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• 2016

Apolipoprotein B-100 (Apo-B100) is a major component of low density lipoprotein (LDL). Apo B-100 protein has 4,536 amino acid sequence and these amino acids are classified into peptide groups A to G with subsequent 20 amino acids (P1-P302). The peptide groups were act as immunoglobulin (Ig) antigens which oxidized via malondialdehyde (MDA). The mimetic peptide P1 (EEEMLENVSLVCPKDAT RFK) out of D-group peptides carrying the highest value of IgG antigens were selected for structural studies that may provide antigen specificity. Circular Dichroism (CD) spectra were measured for peptide secondary structure in the range of 190-250 nm. Experimental results show that P1 exhibit partial of ${\beta}-sheet$ and random coil structure. Homonuclear (COSY, TOCSY, NOESY) 2D-NMR experiments were carried out for NMR signal assignments and structure determination for P1. On the basis of these completely assigned NMR spectra and distance data, distance geometry (DG) and Molecular dynamics (MD) were carried out to determine the structures of P1. The proposed structure was selected by comparisons between experimental NOE spectra and back calculated 2D NOE results from determined structure showing acceptable agreement. The total Root-Mean-Square-Deviation (RMSD) value of P1 obtained upon superposition of all atoms was in the range $0.33{\AA}$. The solution state P1 has mixed structure of ${\beta}-sheet$ (Glu[1] to Cys[12]) and random coil (Pro[13] to Lys[20]). These NMR results are well consistent with secondary structure from experimental results of circular dichroism. Structural studies based on NMR may contribute to the studies of atherosclerosis and observed conformational characteristics of apo B-100 in LDL using monoclonal antibodies.